HolderBook

PERCEPTIVE ADVISORS LLC

Reported holdings as of Q2 2026, from 31 quarterly filings.

CIK
1224962
Reported value
$6.7B
Positions
108
Top 10 weight
47.3%
Filed
2026-08-14
Days after quarter end
45

Holdings

SecurityTickerValue SharesWeightWeight change Held Change
PRAXIS PRECISION MEDICINES IPRAX$681.6M2,035,98610.23%-2.59pp10qHELD
SPYRE THERAPEUTICS INCSYRE$383.5M4,319,4965.76%+2.03pp12q+14.2%+$47.6M
CELCUITY INCCELC$334.5M3,197,2005.02%-1.95pp11q+2.2%+$7.3M
ASCENDIS PHARMA A/SASND$310.4M1,163,7214.66%-newNEW
RHYTHM PHARMACEUTICALS INCRYTM$287.2M2,586,2954.31%+0.28pp12q+9.0%+$23.6M
ROIVANT SCIENCES LTDROIV$286.1M8,085,4614.30%-0.19pp5q-2.4%-$7.1M
RELAY THERAPEUTICS INCRLAY$263.9M14,106,1873.96%+2.07pp3q+44.7%+$81.5M
TRAVERE THERAPEUTICS INCTVTX$213.2M3,752,5743.20%+0.80pp5q-9.4%-$22.2M
KARDIGAN INCKARD$195.6M8,200,6622.94%-newNEW
NUVALENT INCNUVL$195.2M1,580,5052.93%-0.23pp20qHELD
EDGEWISE THERAPEUTICS INCEWTX$177.7M4,373,9742.67%-0.06pp11q-1.1%-$2.0M
APOGEE THERAPEUTICS INCAPGE$173.6M1,308,1132.61%+0.07pp12q-15.1%-$30.8M
AMYLYX PHARMACEUTICALS INCAMLX$149.7M8,334,8822.25%flat8q+0.6%+$898.0K
MEIRAGTX HLDGS PLCMGTX$145.7M10,786,6582.19%+0.44pp31q+4.5%+$6.2M
ORUKA THERAPEUTICS INCORKA$128.0M1,345,0631.92%+0.58pp4q-3.6%-$4.8M
INHIBRX BIOSCIENCES INCINBX$123.0M1,297,7631.85%-0.05pp9q-10.0%-$13.7M
PROTAGONIST THERAPEUTICS INCPTGX$120.4M981,8791.81%-0.73pp14q-20.2%-$30.5M
SOLID BIOSCIENCES INCSLDB$118.9M11,906,6461.79%+0.11pp15qHELD
ZYMEWORKS INCZYME$109.3M4,182,9531.64%-0.08pp15q+19.2%+$17.6M
TANGO THERAPEUTICS INCTNGX$105.6M3,377,0001.58%+1.25pp3q+317.9%+$80.3M
IMMATICS N.VIMTX$105.2M10,383,4561.58%-0.42pp24qHELD
NURIX THERAPEUTICS INCNRIX$104.8M4,320,4221.57%+0.45pp7q+16.4%+$14.8M
BIOCRYST PHARMACEUTICALS INCBCRX$103.1M10,308,8881.55%+0.16pp3q+38.7%+$28.7M
REVOLUTION MEDICINES INCRVMD$98.8M527,6001.48%+0.99pp2q+104.0%+$50.4M
AVALYN PHARMACEUTICALS INCAVLN$88.1M2,675,2961.32%-newNEW
MODERNA INC OPTMRNA$70.0Moptions only1.05%+0.06pp2qOPTIONS
DYNE THERAPEUTICS INCDYN$59.7M2,689,2350.90%-0.76pp8q-42.4%-$44.0M
BIOGEN INCBIIB$59.7M276,1730.90%-newNEW
IMMUNOVANT INCIMVT$52.3M1,357,3830.79%+0.01pp15q-15.0%-$9.2M
UNITEDHEALTH GROUP INCUNH$48.5M116,8060.73%-newNEW
SPDR SERIES TRUST OPTXBI$47.5Moptions only0.71%-newOPTIONS
IONIS PHARMACEUTICALS INCIONS$44.9M566,0000.67%-0.07pp2q+12.3%+$4.9M
SUTRO BIOPHARMA INCSTRO$43.3M1,304,8460.65%+0.30pp2q+82.4%+$19.6M
ALTO NEUROSCIENCE INCANRO$42.5M1,609,8930.64%-0.25pp4q-19.9%-$10.6M
JAZZ PHARMACEUTICALS PLCJAZZ$41.0M170,0000.61%-0.01pp3qHELD
CORVUS PHARMACEUTICALS INCCRVS$39.9M2,667,4410.60%-0.06pp5q+16.4%+$5.6M
SIONNA THERAPEUTICS INCSION$39.8M905,0000.60%+0.08pp6q+37.4%+$10.8M
CYTOMX THERAPEUTICS INCCTMX$39.1M10,439,1850.59%-0.34pp5q+3.4%+$1.3M
ARTIVION INCAORT$39.0M1,737,2900.59%-0.59pp19q+6.1%+$2.2M
X4 PHARMACEUTICALS INCXFOR$37.0M7,933,4910.56%+0.01pp3q+17.7%+$5.6M
CAPRICOR THERAPEUTICS INC OPTCAPR$36.1Moptions only0.54%-newOPTIONS
CORCEPT THERAPEUTICS INCCORT$34.6M398,3850.52%+0.48pp2q+696.8%+$30.3M
REPLIGEN CORPRGEN$33.9M248,2120.51%-0.14pp6q-11.5%-$4.4M
ANTERIS TECHNOLOGIES GLOBALAVR$33.7M3,425,4760.51%+0.13pp7qHELD
RAPPORT THERAPEUTICS INCRAPP$32.2M773,3420.48%+0.07pp4q+14.8%+$4.1M
DAMORA THERAPEUTICS INCDMRA$31.8M1,223,0000.48%-0.14pp2qHELD
CHARLES RIV LABS INTL INCCRL$31.8M140,0000.48%-newNEW
AXSOME THERAPEUTICS INCAXSM$29.0M118,4500.44%-0.06pp13q-21.0%-$7.7M
EYEPOINT INC OPTEYPT$28.6Moptions only0.43%-newOPTIONS
DBV TECHNOLOGIES S ADBVT$27.1M1,653,3500.41%+0.01pp2q+71.4%+$11.3M
IRHYTHM HOLDINGS INCIRTC$26.6M223,7660.40%+0.16pp4q+113.1%+$14.1M
ADAPTIVE BIOTECHNOLOGIES CORADPT$26.1M1,217,3250.39%+0.35pp2q+698.2%+$22.8M
SAB BIOTHERAPEUTICS INCSABS$25.8M6,627,5010.39%-0.09pp3q+3.0%+$763.5K
DANAHER CORP DELDHR$24.8M130,0000.37%-newNEW
TENAX THERAPEUTICS INCTENX$24.7M1,700,0000.37%-0.08pp3q+17.4%+$3.7M
SELLAS LIFE SCIENCES GROUP I OPTSLS$22.1Moptions only0.33%-newOPTIONS
NAUTILUS BIOTECHNOLOGY INCNAUT$21.8M11,634,2110.33%-0.63pp21q-7.6%-$1.8M
ORCHESTRA BIOMED HLDGS INCOBIO$21.7M5,037,9060.33%-0.09pp14qHELD
INTUITIVE SURGICAL INCISRG$20.6M51,8840.31%-0.46pp11q-39.3%-$13.3M
ADLAI NORTYE LTDANL$20.6M1,793,1900.31%-newNEW
CONTINEUM THERAPEUTICS INCCTNM$20.6M1,255,5920.31%-0.01pp9qHELD
NUVECTIS PHARMA INCNVCT$18.4M1,000,0000.28%-newNEW
PALISADE BIO INCPALI$17.6M8,425,0650.26%-0.04pp3q-5.6%-$1.1M
OMADA HEALTH INCOMDA$17.3M786,3300.26%+0.07pp5qHELD
LEONABIO INCLONA$17.1M1,859,3220.26%-0.12pp4qHELD
EVOLUS INCEOLS$17.1M2,459,2850.26%+0.15pp2q+91.1%+$8.1M
NEWAMSTERDAM PHARMA COMPANY OPTNAMS$16.9Moptions only0.25%-newOPTIONS
INVIVYD INCIVVD$16.1M18,490,6360.24%-0.29pp3q-11.4%-$2.1M
CELCUITY INC$14.6M6,500,0000.22%-0.09pp4qDEBT
MIRUM PHARMACEUTICALS INCMIRM$13.5M115,3910.20%-newNEW
SURROZEN INCSRZN$13.1M503,9850.20%+0.07pp2q+119.7%+$7.1M
BETA BIONICS INCBBNX$13.1M832,9440.20%+0.03pp6q-1.2%-$156.7K
AXOGEN INCAXGN$11.4M247,3120.17%-0.28pp3q-64.5%-$20.8M
OSCAR HEALTH INCOSCR$11.4M400,0000.17%-newNEW
OCULIS HOLDING AGOCS$11.2M808,8270.17%-0.09pp3q+63.8%+$4.4M
SEAPORT THERAPEUTICS INCSPTX$10.9M500,0000.16%-newNEW
VIRIDIAN THERAPEUTICS INCVRDN$10.7M581,9800.16%-0.29pp21q-50.3%-$10.8M
BOSTON SCIENTIFIC CORPBSX$10.7M250,0000.16%-newNEW
BILLIONTOONE INCBLLN$10.4M86,8120.16%+0.01pp3q-5.4%-$599.9K
ABIVAX SAABVX$9.9M74,0000.15%-0.57pp4q-77.5%-$34.0M
NATERA INCNTRA$9.4M34,6890.14%-newNEW
Engene Therapeutics IncENGN$8.3M4,822,1690.13%-newNEW
RESEARCH ALLIANCE CORP IIIRACC$8.0M750,0000.12%-newNEW
AGOMAB THERAPEUTICS NVAGMB$7.8M600,0000.12%-0.01pp2qHELD
CULLINAN THERAPEUTICS INCCGEM$7.8M426,4780.12%-newNEW
UNIQURE NVQURE$7.7M168,0000.12%-newNEW
MOBIA MED INC$7.0M523,6540.11%-newNEW
ADAGIO MED HLDGS INCADGM$6.4M9,876,5860.10%-0.12pp8qHELD
GUARDANT HEALTH INCGH$6.2M41,3270.09%-0.45pp3q-86.2%-$38.8M
PHATHOM PHARMACEUTICALS INCPHAT$5.8M532,0000.09%-0.11pp2q-42.5%-$4.3M
OUTLOOK THERAPEUTICS INCOTLK$5.0M3,139,2160.07%-newNEW
COGENT BIOSCIENCES INCCOGT$4.7M121,0820.07%-0.02pp3qHELD
EDESA BIOTECH INCEDSA$4.6M563,2390.07%+0.01pp2qHELD
AVALO THERAPEUTICS INCAVTX$4.1M219,8130.06%+0.02pp6q+57.4%+$1.5M
TWIST BIOSCIENCE CORPTWST$3.8M36,8120.06%-0.08pp2q-75.5%-$11.6M
CRESCENT BIOPHARMA INC.CBIO$3.7M206,9420.06%-0.02pp5qHELD
XERIS BIOPHARMA HOLDINGS INCXERS$3.7M467,0130.06%-newNEW
OUTSET MED INCOM$3.6M833,3330.05%-0.01pp6qHELD
BIODESIX INCBDSX$2.5M108,6940.04%-newNEW
REVOLUTION MEDICINES INCRVMDW$2.3M250,0000.04%+0.03pp11qHELD
CONNECT BIOPHARMA HLDGS LTDCNTB$1.9M792,6960.03%-0.01pp3qHELD
KIORA PHARMACEUTICALS INCKPRX$1.2M438,4710.02%-newNEW
MEDLINE INCMDLN$1.1M28,0000.02%-0.01pp3qHELD
ADMA BIOLOGICS INCADMA$952.2K113,7650.01%-0.07pp31q-75.7%-$3.0M
CUMBERLAND PHARMACEUTICALS ICPIX$628.4K96,9820.01%flat3q-50.8%-$648.0K
EXAGEN INCXGN$534.3K114,8930.01%flat2qHELD
ENSYSCE BIOSCIENCES INCENSC$25.1K86,6660.00%flat7qHELD
SURROZEN INCSRZNW$2.8K166,6660.00%flat20qHELD

By sector

Industry comes from the SIC code on each company's own SEC filings, which is self-reported and sometimes out of date. Derivative exposure is counted with the shares. Securities the SEC assigns no industry - funds, trusts, foreign issues - are shown as not classified rather than dropped.

Biotech & Pharma 81.7%Healthcare Services 5.7%Medical Devices 2.8%Other sectors 1.3%Not classified 8.5%
 
SectorValueShare
Biotech & Pharma$5.4B81.7%
Healthcare Services$380.8M5.7%
Medical Devices$188.1M2.8%
Other sectors$84.7M1.3%
Not classified$566.9M8.5%

Quarter by quarter

QuarterValuePositions NewAddedTrimmed ExitedTop 10 Days to file
Q2 2026$6.7B1082829261447.3%45
Q1 2026$5.1B942023334251.4%59
Q4 2025$5.6B1163932211541.8%48
Q3 2025$3.5B922130171344.9%45
Q2 2025$2.7B842110332354.2%45
Q1 2025$2.8B861514282754.9%128
Q4 2024$3.6B982012432851.3%45
Q3 2024$4.7B1061523241846.4%45
Q2 2024$4.2B1092120302047.2%47
Q1 2024$5.7B1082636171739.5%128
Q4 2023$4.5B992126211748.4%57
Q3 2023$3.0B951220271045.9%45
Q2 2023$3.5B931520292143.6%55
Q1 2023$3.4B992019201646.4%46
Q4 2022$3.6B951418253548.2%45
Q3 2022$3.4B1161725241243.9%45
Q2 2022$3.2B1111113473552.7%46
Q1 2022$5.0B1351451142644.7%46
Q4 2021$13.0B1472411741643.2%103
Q3 2021$6.9B1392501143544.2%64
Q2 2021$15.4B1493011261939.1%47
Q1 2021$7.9B1383518373642.8%135
Q4 2020$9.3B1393921132643.1%47
Q3 2020$6.8B1263118232943.8%47
Q2 2020$6.2B1243724172445.7%48
Q1 2020$3.8B1112621162954.9%48
Q4 2019$5.0B1143124172553.6%50
Q3 2019$3.7B1082622142152.0%45
Q2 2019$4.4B1032423172353.1%45
Q1 2019$3.5B102282582451.4%46
Q4 2018$2.6B98000051.5%45

Rows marked UNVERIFIED ID, PLACEHOLDER ID, TICKER AS ID or NON-CUSIP ID carry an identifier that is not a valid CUSIP. They are shown because the filer reported that money, but treat the security named with caution - hover the chip for what is wrong with it, and see the methodology.

Held counts consecutive filings in which this manager reported the position, and can reach further back than the quarters listed above: the tabs begin at Q4 2018 because earlier coverage is too sparse to describe a market, but tenure is counted over every filing we hold, some reaching to 2007. A position sold and later rebought starts again from one.

Weight change is the shift in this position's share of the whole book, in percentage points. It is the more useful column: when money flows into or out of a broad fund, almost every holding is bought or sold at once, so added and trimmed largely track flows. A weight that rose while the book shrank is a decision. Both compare with the previous quarter this filer reported, not the previous calendar quarter.