DYNE THERAPEUTICS INC (DYN)
Institutional ownership reported to the SEC as of Q2 2026, across 24 quarters.
237
Reporting holders
$3.6B
Reported value
85.6%
Of shares outstanding
0.2%
Held as options
+15
Holder change
Institutions report 159,892,212 shares against 186,746,431 outstanding. Shares only - option lines are excluded, which is why this can be compared with the company at all. The count comes from the cover page of the company's own most recent report, so it is dated when that was filed rather than at quarter end. A figure this high can overstate: where an adviser and a sub-adviser both report the same shares, both are counted.
Options share is the part of reported value carried in derivative lines rather than shares. A high figure means institutions are expressing a view on this security without owning much of it.
Holders
| Filer | Value | Shares | Their book | Held | Change |
|---|---|---|---|---|---|
| BlackRock, Inc. | $275.5M | 12,404,330 | 0.00% | 8q | +6.0%+$15.6M |
| Jupiter Topco LLC | $266.6M | 11,997,738 | 0.11% | new | FIRST |
| FMR LLC | $248.9M | 11,207,000 | 0.01% | 19q | +25.8%+$51.0M |
| STATE STREET CORP | $165.6M | 7,458,263 | 0.00% | 23q | +12.1%+$17.9M |
| Orbis Allan Gray Ltd | $155.6M | 7,006,542 | 0.53% | 3q | +3.6%+$5.4M |
| Atlas Venture Life Science Advisors, LLC | $151.0M | 6,800,099 | 17.14% | 19q | -25.5%-$51.8M |
| VANGUARD CAPITAL MANAGEMENT LLC | $140.2M | 6,310,969 | 0.00% | 2q | -1.5%-$2.1M |
| Palo Alto Investors LP | $109.8M | 4,942,563 | 5.06% | 6q | +199.0%+$73.1M |
| TCG Crossover Management, LLC | $102.5M | 4,615,144 | 2.46% | 14q | HELD |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $89.9M | 4,048,428 | 0.00% | 2q | -2.7%-$2.5M |
| FCPM III SERVICES B.V. | $85.5M | 3,848,256 | 11.39% | 11q | -17.1%-$17.7M |
| GEODE CAPITAL MANAGEMENT, LLC | $83.2M | 3,743,427 | 0.00% | 23q | +6.8%+$5.3M |
| Vestal Point Capital, LP | $75.0M | 3,375,000 | 1.75% | 6q | -15.6%-$13.9M |
| ORBIMED ADVISORS LLC | $71.9M | 3,235,684 | 1.33% | 10q | +10.9%+$7.1M |
| Frazier Life Sciences Management, L.P. | $70.0M | 3,153,082 | 1.53% | 6q | HELD |
| ARMISTICE CAPITAL, LLC | $68.6M | 3,087,226 | 0.84% | 13q | -2.8%-$2.0M |
| JPMORGAN CHASE & CO | $67.2M | 3,151,656 | 0.00% | 23q | -3.1%-$2.2M |
| PERCEPTIVE ADVISORS LLC | $59.7M | 2,689,235 | 0.90% | 8q | -42.4%-$44.0M |
| Logos Global Management LP | $56.6M | 2,550,000 | 2.44% | 24q | +82.1%+$25.5M |
| BANK OF AMERICA CORP /DE/ | $49.6M | 2,233,398 | 0.00% | 23q | +54.7%+$17.5M |
| Venrock Adviser, LLC | $48.3M | 2,173,913 | 1.46% | 13q | HELD |
| GOLDMAN SACHS GROUP INC | $47.9M | 2,157,195 | 0.00% | 24q | +25.2%+$9.6M |
| Siren, L.L.C. | $47.3M | 2,129,125 | 0.96% | 8q | -4.5%-$2.2M |
| FRANKLIN RESOURCES INC | $45.1M | 2,030,819 | 0.01% | 24q | +1.1%+$482.8K |
| DIMENSIONAL FUND ADVISORS LP | $43.2M | 1,946,479 | 0.01% | 3q | +104.6%+$22.1M |
| MPM BIOIMPACT LLC | $42.7M | 1,922,093 | 2.60% | 5q | +36.5%+$11.4M |
| SAMLYN CAPITAL, LLC | $39.0M | 1,754,708 | 0.63% | 3q | -8.7%-$3.7M |
| Sofinnova Investments, Inc. | $36.8M | 1,658,384 | 1.90% | 13q | +1.5%+$543.9K |
| Vivo Capital, LLC | $34.6M | 1,557,466 | 3.16% | 24q | HELD |
| Aberdeen Group plc | $34.2M | 1,539,434 | 0.05% | 7q | +7.6%+$2.4M |
| Deep Track Capital, LP | $33.3M | 1,500,000 | 0.48% | 4q | -25.0%-$11.1M |
| MARSHALL WACE, LLP | $33.1M | 1,488,917 | 0.03% | 5q | +1690.7%+$31.2M |
| Polar Capital Holdings Plc | $28.6M | 1,286,811 | 0.07% | 4q | -5.3%-$1.6M |
| NORTHERN TRUST CORP | $28.4M | 1,278,081 | 0.00% | 23q | +6.6%+$1.8M |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $26.7M | 1,202,203 | 0.00% | 23q | +3.8%+$973.1K |
| Sixth Street Partners Management Company, L.P. | $26.7M | 1,202,203 | 0.00% | new | NEW |
| CITADEL ADVISORS LLC | $26.4M | 1,143,958 | 0.00% | 24q | +468.7%+$21.7M |
| Saturn V Capital Management LP | $23.5M | 1,057,493 | 3.37% | 5q | +9.4%+$2.0M |
| VANGUARD FIDUCIARY TRUST CO | $22.0M | 988,949 | 0.00% | 2q | +4.4%+$922.0K |
| NOVO HOLDINGS A/S | $21.3M | 960,394 | 1.24% | new | NEW |
| Rock Springs Capital Management LP | $20.9M | 942,154 | 1.02% | 10q | -3.1%-$667.3K |
| BRAIDWELL LP | $20.5M | 921,598 | 0.76% | 7q | -45.2%-$16.9M |
| FRONTIER CAPITAL MANAGEMENT CO LLC | $19.4M | 874,138 | 0.18% | 7q | +6.4%+$1.2M |
| BAKER BROS. ADVISORS LP | $18.1M | 813,449 | 0.09% | 3q | HELD |
| Fiera Capital Corp | $17.5M | 789,989 | 0.06% | 2q | -42.8%-$13.1M |
| MORGAN STANLEY | $16.6M | 746,200 | 0.00% | 23q | -19.7%-$4.1M |
| Artisan Partners Limited Partnership | $14.7M | 659,786 | 0.02% | 3q | +6.5%+$895.7K |
| RAYMOND JAMES FINANCIAL INC | $12.8M | 576,350 | 0.00% | 7q | +27.6%+$2.8M |
| TD Asset Management Inc | $12.2M | 548,112 | 0.01% | 4q | +3.6%+$417.5K |
| ALGERT GLOBAL LLC | $11.2M | 506,273 | 0.13% | 17q | -44.3%-$8.9M |
| WASATCH ADVISORS LP | $9.9M | 443,668 | 0.06% | 16q | HELD |
| UBS Group AG | $9.8M | 443,284 | 0.00% | 19q | +16.5%+$1.4M |
| MILLENNIUM MANAGEMENT LLC | $9.6M | 431,850 | 0.00% | 8q | +172.4%+$6.1M |
| Clearbridge Investments, LLC | $9.2M | 415,131 | 0.01% | 3q | +3.0%+$264.4K |
| Bank of New York Mellon Corp | $9.1M | 409,801 | 0.00% | 24q | +2.0%+$181.8K |
| ArrowMark Colorado Holdings LLC | $8.8M | 397,221 | 0.37% | 24q | -41.1%-$6.1M |
| Nuveen, LLC | $8.6M | 386,787 | 0.00% | 6q | -46.2%-$7.4M |
| RENAISSANCE TECHNOLOGIES LLC | $8.0M | 360,572 | 0.01% | 4q | -32.4%-$3.8M |
| Tetragon Partners GP Ltd | $7.9M | 356,657 | 1.25% | 5q | +38.2%+$2.2M |
| NEW YORK STATE COMMON RETIREMENT FUND | $7.9M | 355,953 | 0.01% | 23q | +6.7%+$498.7K |
| Granahan Investment Management, LLC | $7.5M | 338,565 | 0.27% | new | NEW |
| University of Wisconsin Foundation | $7.0M | 313,559 | 5.51% | 4q | -35.3%-$3.8M |
| MOORE CAPITAL MANAGEMENT, LP | $6.8M | 305,794 | 0.10% | 2q | +288.2%+$5.0M |
| Squarepoint Ops LLC | $6.7M | 300,074 | 0.01% | 10q | -64.0%-$11.9M |
| Fisher Asset Management, LLC | $6.6M | 298,505 | 0.00% | 3q | -7.6%-$545.2K |
| AMERIPRISE FINANCIAL INC | $6.6M | 298,317 | 0.00% | 9q | -8.5%-$613.6K |
| Ensign Peak Advisors, Inc | $6.4M | 289,730 | 0.01% | 24q | -70.8%-$15.6M |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | $6.0M | 269,985 | 0.00% | 20q | +12.8%+$681.8K |
| Alyeska Investment Group, L.P. | $5.4M | 245,278 | 0.01% | new | NEW |
| Catalio Capital Management, LP | $5.4M | 244,929 | 1.02% | 3q | -13.4%-$844.5K |
| DEUTSCHE BANK AG\ | $5.4M | 242,392 | 0.00% | 23q | +9.6%+$472.4K |
| Swiss National Bank | $5.2M | 232,000 | 0.00% | 21q | +1.7%+$86.6K |
| WELLS FARGO & COMPANY/MN | $4.9M | 220,664 | 0.00% | 14q | -24.2%-$1.6M |
| SPHERA FUNDS MANAGEMENT LTD. | $4.4M | 199,594 | 0.58% | 8q | +24.3%+$866.2K |
| SummitTX Capital, L.P. | $4.3M | 194,643 | 0.11% | 6q | -0.8%-$34.3K |
| CITIGROUP INC | $4.2M | 187,915 | 0.00% | 23q | +397.2%+$3.3M |
| RHUMBLINE ADVISERS | $4.1M | 183,799 | 0.00% | 22q | -1.8%-$76.0K |
| VOYA INVESTMENT MANAGEMENT LLC | $3.9M | 174,457 | 0.00% | 21q | +101.4%+$2.0M |
| HighVista Strategies LLC | $3.8M | 171,961 | 0.87% | 3q | -6.0%-$243.6K |
| ALPS ADVISORS INC | $3.7M | 167,082 | 0.02% | new | NEW |
| Invesco Ltd. | $3.7M | 164,598 | 0.00% | 21q | -33.9%-$1.9M |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | $3.5M | 157,916 | 0.00% | 5q | -4.2%-$154.8K |
| Y-Intercept (Hong Kong) Ltd | $3.5M | 156,203 | 0.07% | 3q | +139.7%+$2.0M |
| AXXCESS WEALTH MANAGEMENT, LLC | $3.4M | 155,270 | 0.05% | new | NEW |
| Darwin Wealth Management, LLC | $3.4M | 155,270 | 0.94% | 7q | HELD |
| Aegis Wealth Management LLC | $3.3M | 150,030 | 1.57% | 6q | +11.1%+$333.1K |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | $3.3M | 150,000 | 0.00% | 5q | -85.0%-$18.9M |
| Woodline Partners LP | $3.3M | 149,388 | 0.01% | 3q | HELD |
| ALLIANCEBERNSTEIN L.P. | $3.1M | 172,080 | 0.00% | 18q | +26.6%+$655.2K |
| Schonfeld Strategic Advisors LLC | $3.0M | 134,752 | 0.01% | new | NEW |
| XTX Topco Ltd | $2.8M | 125,786 | 0.04% | 6q | +194.5%+$1.8M |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $2.8M | 47,127 | 0.00% | 16q | -56.7%-$3.6M |
| Jain Global LLC | $2.6M | 116,341 | 0.01% | new | NEW |
| Rafferty Asset Management, LLC | $2.6M | 115,102 | 0.01% | 13q | -37.1%-$1.5M |
| Russell Investments Group, Ltd. | $2.3M | 105,553 | 0.00% | 16q | +163.6%+$1.5M |
| Legal & General Group Plc | $2.2M | 97,940 | 0.00% | 24q | +1.5%+$32.8K |
| FIDEURAM - INTESA SANPAOLO PRIVATE BANKING S.P.A. | $1.9M | 87,069 | 0.06% | new | NEW |
| AQR CAPITAL MANAGEMENT LLC | $1.9M | 84,054 | 0.00% | 6q | HELD |
| VANGUARD ASSET MANAGEMENT, Ltd | $1.8M | 81,238 | 0.00% | 2q | +10.8%+$176.1K |
| JANE STREET GROUP, LLC | $1.8M | options only | 0.00% | 12q | OPTIONS |
Five percent filings
Anyone crossing 5% of a company must say so within days - far sooner than the next quarterly holdings report. A 13D declares an intent to influence the company; a 13G is the passive version. See all activist filings →
| Filed | Form | Filer | % of class |
|---|---|---|---|
| 2026-08-13 | 13G/A | JANUS HENDERSON GROUP Ltd. | 7.3% |
| 2026-08-13 | 13G/A | Atlas Venture Fund XI, L.P.with 8 co-filers | 2.4% |
| 2026-08-06 | 13G/A | FMR LLCwith 1 co-filers | 6.8% |
| 2026-07-28 | 13G/A | BlackRock, Inc. | 7.0% |
Quarter by quarter
Coverage begins with the quarter ending 2018-12-31. Earlier filings exist only as occasional late amendments, too sparse to describe a market, so they are not shown.
| Quarter | Holders | Value | Shares | New | Added | Trimmed | Options |
|---|---|---|---|---|---|---|---|
| Q2 2026 | 237 | $3.6B | 159,892,212 | 42 | 82 | 73 | 0.2% |
| Q1 2026 | 222 | $2.8B | 156,327,877 | 35 | 99 | 54 | 0.2% |
| Q4 2025 | 219 | $3.1B | 158,223,906 | 48 | 89 | 58 | 0.4% |
| Q3 2025 | 197 | $2.0B | 155,484,471 | 37 | 104 | 37 | 0.3% |
| Q2 2025 | 184 | $1.2B | 125,140,022 | 22 | 87 | 51 | 0.1% |
| Q1 2025 | 192 | $1.3B | 118,774,768 | 41 | 74 | 40 | 0.3% |
| Q4 2024 | 191 | $2.6B | 109,158,852 | 28 | 63 | 58 | 0.5% |
| Q3 2024 | 191 | $4.0B | 109,860,829 | 42 | 67 | 52 | 0.4% |
| Q2 2024 | 182 | $3.8B | 108,733,326 | 41 | 75 | 42 | 0.2% |
| Q1 2024 | 161 | $2.7B | 96,135,614 | 59 | 65 | 26 | 0.4% |
| Q4 2023 | 119 | $977.6M | 72,032,098 | 20 | 40 | 35 | 2.2% |
| Q3 2023 | 109 | $528.5M | 58,792,522 | 13 | 44 | 29 | 0.6% |
| Q2 2023 | 112 | $655.9M | 58,523,889 | 15 | 51 | 26 | 0.0% |
| Q1 2023 | 112 | $617.0M | 53,785,726 | 19 | 46 | 22 | 0.0% |
| Q4 2022 | 93 | $541.0M | 46,756,392 | 16 | 29 | 25 | 0.2% |
| Q3 2022 | 103 | $576.1M | 45,327,447 | 27 | 31 | 24 | 0.1% |
| Q2 2022 | 88 | $320.7M | 46,680,147 | 8 | 24 | 29 | 0.0% |
| Q1 2022 | 93 | $456.6M | 47,732,363 | 11 | 23 | 32 | 0.0% |
| Q4 2021 | 92 | $568.3M | 47,795,414 | 14 | 32 | 17 | 0.0% |
| Q3 2021 | 81 | $572.8M | 35,266,443 | 15 | 23 | 20 | 0.0% |
| Q2 2021 | 75 | $753.4M | 35,805,178 | 15 | 29 | 13 | 0.0% |
| Q1 2021 | 73 | $533.3M | 34,339,631 | 17 | 34 | 11 | 0.0% |
| Q4 2020 | 69 | $614.7M | 29,301,578 | 31 | 13 | 9 | 0.0% |
| Q3 2020 | 50 | $553.5M | 27,487,960 | 49 | 0 | 0 | 0.0% |