UNIQURE NV (QURE)
Institutional ownership reported to the SEC as of Q2 2026, across 31 quarters.
254
Reporting holders
$3.7B
Reported value
96.1%
Of shares outstanding
17.9%
Held as options
+36
Holder change
Institutions report 66,629,427 shares against 69,366,412 outstanding. Shares only - option lines are excluded, which is why this can be compared with the company at all. The count comes from the cover page of the company's own most recent report, so it is dated when that was filed rather than at quarter end. A figure this high can overstate: where an adviser and a sub-adviser both report the same shares, both are counted.
Options share is the part of reported value carried in derivative lines rather than shares. A high figure means institutions are expressing a view on this security without owning much of it.
Holders
| Filer | Value | Shares | Their book | Held | Change |
|---|---|---|---|---|---|
| Avoro Capital Advisors LLC | $309.9M | 6,727,777 | 2.78% | 7q | +12.9%+$35.4M |
| JPMORGAN CHASE & CO | $231.1M | 4,867,755 | 0.01% | 31q | +71.6%+$96.4M |
| RTW INVESTMENTS, LP | $181.5M | 3,941,572 | 1.55% | 8q | +52.4%+$62.4M |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $161.0M | 496,897 | 0.01% | 31q | -50.4%-$163.9M |
| STATE STREET CORP | $133.8M | 2,903,825 | 0.00% | 31q | +28.5%+$29.6M |
| Aberdeen Group plc | $131.2M | 2,848,117 | 0.18% | 11q | -46.3%-$113.2M |
| Nantahala Capital Management, LLC | $130.5M | 911,320 | 2.17% | 31q | +284.4%+$96.6M |
| CITADEL ADVISORS LLC | $115.5M | 910,338 | 0.01% | 31q | +125.0%+$64.2M |
| JANE STREET GROUP, LLC | $103.6M | 1,610,483 | 0.01% | 30q | +153.2%+$62.7M |
| BlackRock, Inc. | $86.5M | 1,877,453 | 0.00% | 8q | +8.3%+$6.6M |
| Caption Management, LLC | $84.9M | 15,000 | 0.40% | 9q | -95.1%-$1.6B |
| ORBIMED ADVISORS LLC | $83.3M | 1,807,486 | 1.54% | 4q | -15.4%-$15.1M |
| JENNISON ASSOCIATES LLC | $71.9M | 1,561,412 | 0.04% | 5q | +26.6%+$15.1M |
| Boxer Capital Management, LLC | $69.2M | 1,503,300 | 5.21% | 7q | +127.1%+$38.8M |
| GOLDMAN SACHS GROUP INC | $68.0M | 1,475,956 | 0.01% | 31q | +16.8%+$9.8M |
| TWO SIGMA INVESTMENTS, LP | $67.3M | 1,462,024 | 0.05% | 16q | -45.4%-$55.9M |
| Two Seas Capital LP | $66.4M | 1,441,410 | 1.31% | 2q | +10.9%+$6.5M |
| FMR LLC | $58.5M | 1,270,068 | 0.00% | 31q | -27.2%-$21.8M |
| MAK CAPITAL ONE LLC | $56.7M | 1,232,051 | 7.95% | 2q | +179.2%+$36.4M |
| MPM BIOIMPACT LLC | $56.5M | 1,225,855 | 3.44% | 3q | -10.5%-$6.6M |
| TUDOR INVESTMENT CORP ET AL | $49.8M | 328,889 | 0.07% | 4q | HELD |
| MORGAN STANLEY | $49.1M | 1,066,639 | 0.00% | 35q | +191.3%+$32.3M |
| Assenagon Asset Management S.A. | $47.3M | 1,027,060 | 0.03% | 3q | +599.9%+$40.5M |
| GROUP ONE TRADING LLC | $43.9M | options only | 0.06% | 31q | OPTIONS |
| Vestal Point Capital, LP | $43.1M | 935,000 | 1.01% | 2q | +160.4%+$26.5M |
| MAVERICK CAPITAL LTD | $42.6M | 925,383 | 0.38% | 3q | +32.6%+$10.5M |
| Fiera Capital Corp | $41.9M | 909,141 | 0.15% | 3q | +11.3%+$4.2M |
| Integral Health Asset Management, LLC | $41.5M | 900,000 | 1.64% | 8q | HELD |
| 683 Capital Management, LLC | $41.0M | 575,000 | 2.02% | 31q | +15.0%+$5.4M |
| GEODE CAPITAL MANAGEMENT, LLC | $39.7M | 860,631 | 0.00% | 31q | +7.0%+$2.6M |
| CITIGROUP INC | $37.5M | 127,944 | 0.01% | 31q | -75.9%-$118.4M |
| Longaeva Partners L.P. | $37.1M | 804,594 | 0.81% | new | NEW |
| VANGUARD CAPITAL MANAGEMENT LLC | $35.9M | 779,779 | 0.00% | 2q | +12.2%+$3.9M |
| Invesco Ltd. | $28.9M | 627,823 | 0.00% | new | NEW |
| First Turn Management, LLC | $28.0M | 608,925 | 3.00% | 3q | -1.1%-$302.3K |
| Point72 Asset Management, L.P. | $27.9M | 606,212 | 0.03% | new | NEW |
| Balyasny Asset Management L.P. | $27.0M | 586,582 | 0.03% | 11q | -39.2%-$17.4M |
| Kinetic Partners Management, LP | $26.8M | 581,000 | 0.64% | new | NEW |
| BANK OF AMERICA CORP /DE/ | $26.7M | 578,786 | 0.00% | 31q | +134.5%+$15.3M |
| MILLENNIUM MANAGEMENT LLC | $25.0M | 343,126 | 0.01% | 15q | -56.7%-$32.8M |
| DIADEMA PARTNERS LP | $24.6M | options only | 3.11% | 7q | OPTIONS |
| GILDER GAGNON HOWE & CO LLC | $24.5M | 530,979 | 0.25% | new | NEW |
| Nationale-Nederlanden Powszechne Towarzystwo Emerytalne S.A. | $24.0M | 521,677 | 1.32% | 4q | HELD |
| IMC-Chicago, LLC | $23.9M | options only | 0.01% | 3q | OPTIONS |
| UBS Group AG | $21.5M | 467,571 | 0.00% | 31q | -4.2%-$933.5K |
| Voss Capital, LP | $20.7M | 450,361 | 0.96% | 5q | -25.6%-$7.1M |
| Rubric Capital Management LP | $18.8M | 408,581 | 0.17% | new | NEW |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $18.6M | 403,338 | 0.00% | 24q | +7.3%+$1.3M |
| Sixth Street Partners Management Company, L.P. | $18.6M | 403,338 | 0.00% | new | NEW |
| READYSTATE ASSET MANAGEMENT LP | $18.5M | 400,989 | 0.63% | 3q | -20.5%-$4.8M |
| Creek Drive Management Group LLC | $17.8M | 337,000 | 8.65% | 3q | +124.7%+$9.9M |
| Affinity Asset Advisors, LLC | $17.3M | 175,000 | 0.78% | 6q | HELD |
| VANGUARD FIDUCIARY TRUST CO | $17.0M | 369,607 | 0.00% | 2q | +11.2%+$1.7M |
| Privium Fund Management B.V. | $15.1M | 328,322 | 2.78% | 19q | -32.5%-$7.3M |
| ADAR1 Capital Management, LLC | $15.0M | 324,672 | 0.68% | 4q | +326.0%+$11.4M |
| FourWorld Capital Management LLC | $14.1M | 87,000 | 12.86% | new | NEW |
| MARSHALL WACE, LLP | $14.0M | 304,702 | 0.01% | 9q | +148.3%+$8.4M |
| BRAIDWELL LP | $13.9M | 301,652 | 0.51% | new | NEW |
| SIMPLEX TRADING, LLC | $13.8M | 110,219 | 0.01% | 31q | -52.4%-$15.2M |
| Squarepoint Ops LLC | $12.9M | 280,300 | 0.01% | 8q | -19.0%-$3.0M |
| FRANKLIN RESOURCES INC | $11.3M | 245,272 | 0.00% | 8q | -49.0%-$10.9M |
| NEW YORK STATE COMMON RETIREMENT FUND | $11.2M | 244,238 | 0.01% | 3q | +65.5%+$4.5M |
| BARCLAYS PLC | $11.1M | 17,866 | 0.00% | 25q | -89.3%-$93.3M |
| NOMURA ASSET MANAGEMENT INTERNATIONAL INC. | $10.0M | 217,500 | 0.02% | 3q | -15.8%-$1.9M |
| FLAX POND CAPITAL, LLC | $10.0M | 324,757 | 3.69% | 3q | +113.6%+$5.3M |
| NORTHERN TRUST CORP | $9.8M | 212,935 | 0.00% | 31q | +25.3%+$2.0M |
| Parkman Healthcare Partners LLC | $9.6M | 208,170 | 0.98% | 7q | +0.6%+$61.2K |
| D. E. Shaw & Co., Inc. | $9.6M | 207,629 | 0.00% | 13q | +29.2%+$2.2M |
| LMR Partners LLP | $9.1M | options only | 0.03% | 2q | OPTIONS |
| Diametric Capital, LP | $9.1M | 197,242 | 0.96% | 4q | +972.3%+$8.2M |
| PICTON MAHONEY ASSET MANAGEMENT | $8.3M | 181,215 | 0.06% | new | NEW |
| Trexquant Investment LP | $7.9M | 171,149 | 0.05% | new | NEW |
| PERCEPTIVE ADVISORS LLC | $7.7M | 168,000 | 0.12% | new | NEW |
| Freshford Capital Management, LLC | $7.5M | 161,855 | 2.55% | new | NEW |
| Kalehua Capital Management LLC | $7.3M | 158,814 | 2.33% | 2q | -68.4%-$15.8M |
| AMERIPRISE FINANCIAL INC | $7.0M | 152,343 | 0.00% | 31q | +33.3%+$1.8M |
| Casdin Capital, LLC | $6.9M | 150,000 | 0.35% | new | NEW |
| WELLS FARGO & COMPANY/MN | $6.9M | 149,971 | 0.00% | 31q | -27.5%-$2.6M |
| Hennion & Walsh Asset Management, Inc. | $6.5M | 142,113 | 0.19% | 5q | +107.3%+$3.4M |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $6.5M | 141,093 | 0.00% | new | NEW |
| SIG BROKERAGE, LP | $6.1M | options only | 0.12% | 4q | OPTIONS |
| K2 PRINCIPAL FUND, L.P. | $5.9M | 78,601 | 0.43% | 2q | -33.7%-$3.0M |
| ENVESTNET ASSET MANAGEMENT INC | $5.8M | 126,576 | 0.00% | 4q | +31.1%+$1.4M |
| ROYAL BANK OF CANADA | $5.7M | 124,293 | 0.00% | 31q | +15.2%+$755.6K |
| Susquehanna Portfolio Strategies, LLC | $5.6M | 121,869 | 0.09% | 4q | -12.3%-$787.6K |
| Hudson Bay Capital Management LP | $5.5M | 120,000 | 0.02% | 27q | -24.3%-$1.8M |
| NAN FUNG TRINITY (HK) LTD | $5.3M | 115,494 | 0.53% | 3q | HELD |
| BOOTHBAY FUND MANAGEMENT, LLC | $4.9M | 28,551 | 0.06% | 13q | -68.8%-$10.8M |
| SILVERARC CAPITAL MANAGEMENT, LLC | $4.8M | 105,000 | 0.50% | new | NEW |
| Ghisallo Capital Management LLC | $4.6M | 100,000 | 0.09% | new | NEW |
| Pekin Hardy Strauss, Inc. | $4.3M | 94,250 | 0.38% | 3q | -16.3%-$844.0K |
| Swiss National Bank | $4.3M | 94,100 | 0.00% | 5q | +19.1%+$695.5K |
| STEMPOINT CAPITAL LP | $4.1M | 88,115 | 0.70% | 7q | -43.6%-$3.1M |
| PEAK6 LLC | $4.0M | 6,047 | 0.01% | 7q | +99.0%+$2.0M |
| Marex Group Ltd | $3.8M | 81,500 | 0.02% | 4q | +1.9%+$68.5K |
| Exome Asset Management LLC | $3.7M | 81,056 | 2.30% | new | NEW |
| Alyeska Investment Group, L.P. | $3.5M | 75,000 | 0.01% | new | NEW |
| Burkehill Global Management, LP | $3.5M | 75,000 | 0.12% | new | NEW |
| Walleye Capital LLC | $3.3M | 51,225 | 0.01% | 8q | -42.1%-$2.4M |
| FRED ALGER MANAGEMENT, LLC | $3.2M | 69,561 | 0.01% | 4q | +221.2%+$2.2M |
Five percent filings
Anyone crossing 5% of a company must say so within days - far sooner than the next quarterly holdings report. A 13D declares an intent to influence the company; a 13G is the passive version. See all activist filings →
| Filed | Form | Filer | % of class |
|---|---|---|---|
| 2026-08-14 | 13G/A | G1 Execution Services, LLCwith 4 co-filers | 4.8% |
| 2026-08-14 | 13G | RTW Investments, LPwith 1 co-filers | 5.7% |
| 2026-07-20 | 13G/A | Aberdeen Group plcwith 1 co-filers | 4.5% |
| 2026-07-16 | 13G | JPMORGAN CHASE & CO | 7.0% |
Quarter by quarter
Coverage begins with the quarter ending 2018-12-31. Earlier filings exist only as occasional late amendments, too sparse to describe a market, so they are not shown.
| Quarter | Holders | Value | Shares | New | Added | Trimmed | Options |
|---|---|---|---|---|---|---|---|
| Q2 2026 | 254 | $3.7B | 66,629,427 | 81 | 82 | 62 | 17.9% |
| Q1 2026 | 218 | $1.3B | 59,356,468 | 40 | 72 | 62 | 25.2% |
| Q4 2025 | 227 | $1.8B | 61,516,453 | 64 | 71 | 61 | 16.3% |
| Q3 2025 | 217 | $3.8B | 55,350,998 | 91 | 42 | 62 | 14.3% |
| Q2 2025 | 141 | $836.6M | 53,128,154 | 26 | 40 | 53 | 11.5% |
| Q1 2025 | 136 | $551.4M | 49,218,615 | 23 | 51 | 35 | 5.0% |
| Q4 2024 | 135 | $783.8M | 41,050,539 | 26 | 34 | 45 | 7.6% |
| Q3 2024 | 125 | $200.8M | 38,837,632 | 27 | 34 | 35 | 4.1% |
| Q2 2024 | 114 | $164.2M | 34,543,593 | 15 | 34 | 34 | 6.0% |
| Q1 2024 | 123 | $197.9M | 35,345,668 | 18 | 48 | 30 | 6.0% |
| Q4 2023 | 135 | $301.1M | 42,717,761 | 23 | 41 | 51 | 4.3% |
| Q3 2023 | 146 | $244.4M | 35,752,634 | 24 | 55 | 37 | 3.0% |
| Q2 2023 | 163 | $461.2M | 35,488,239 | 35 | 53 | 52 | 12.7% |
| Q1 2023 | 146 | $911.3M | 42,967,263 | 26 | 39 | 52 | 5.0% |
| Q4 2022 | 136 | $896.9M | 36,572,597 | 34 | 36 | 47 | 7.6% |
| Q3 2022 | 157 | $833.7M | 42,057,715 | 18 | 68 | 48 | 5.4% |
| Q2 2022 | 167 | $810.7M | 40,627,887 | 24 | 59 | 56 | 6.5% |
| Q1 2022 | 170 | $739.2M | 38,313,021 | 27 | 70 | 43 | 5.1% |
| Q4 2021 | 172 | $920.6M | 37,877,770 | 26 | 57 | 62 | 14.6% |
| Q3 2021 | 174 | $1.4B | 37,030,211 | 44 | 59 | 44 | 13.4% |
| Q2 2021 | 156 | $1.3B | 35,921,627 | 27 | 52 | 52 | 13.9% |
| Q1 2021 | 156 | $1.4B | 36,324,626 | 18 | 68 | 41 | 10.1% |
| Q4 2020 | 164 | $1.4B | 35,283,640 | 27 | 59 | 49 | 8.9% |
| Q3 2020 | 163 | $1.4B | 35,450,922 | 36 | 55 | 43 | 10.0% |
| Q2 2020 | 177 | $1.8B | 35,246,294 | 32 | 70 | 49 | 10.3% |
| Q1 2020 | 176 | $1.8B | 35,457,690 | 28 | 66 | 45 | 8.6% |
| Q4 2019 | 188 | $2.7B | 34,694,847 | 40 | 74 | 42 | 7.5% |
| Q3 2019 | 162 | $1.4B | 32,038,440 | 44 | 59 | 41 | 13.0% |
| Q2 2019 | 153 | $2.8B | 28,712,009 | 46 | 44 | 40 | 19.9% |
| Q1 2019 | 134 | $1.5B | 22,716,427 | 51 | 36 | 36 | 10.2% |
| Q4 2018 | 96 | $710.4M | 22,804,898 | 2 | 0 | 3 | 7.5% |