CRESCENT BIOPHARMA INC. (CBIO)
Institutional ownership reported to the SEC as of Q2 2026, across 28 quarters.
80
Reporting holders
$520.7M
Reported value
77.9%
Of shares outstanding
0.0%
Held as options
+21
Holder change
Institutions report 28,928,248 shares against 37,143,940 outstanding. Shares only - option lines are excluded, which is why this can be compared with the company at all. The count comes from the cover page of the company's own most recent report, so it is dated when that was filed rather than at quarter end.
Options share is the part of reported value carried in derivative lines rather than shares. A high figure means institutions are expressing a view on this security without owning much of it.
Holders
| Filer | Value | Shares | Their book | Held | Change |
|---|---|---|---|---|---|
| FMR LLC | $74.4M | 4,133,514 | 0.00% | 5q | HELD |
| BVF INC/IL | $49.5M | 2,748,763 | 1.27% | 5q | HELD |
| Fairmount Funds Management LLC | $49.5M | 2,747,866 | 3.27% | 5q | HELD |
| Venrock Adviser, LLC | $38.4M | 2,133,576 | 1.16% | 5q | HELD |
| Logos Global Management LP | $34.2M | 1,900,000 | 1.47% | 5q | +293.8%+$25.5M |
| FCPM III SERVICES B.V. | $30.2M | 1,677,852 | 4.02% | 3q | HELD |
| Balyasny Asset Management L.P. | $29.9M | 1,662,917 | 0.04% | 3q | +10.1%+$2.8M |
| Vestal Point Capital, LP | $29.3M | 1,630,000 | 0.69% | 3q | +8.7%+$2.3M |
| Opaleye Management Inc. | $23.7M | 1,319,351 | 2.15% | 3q | +0.5%+$121.2K |
| BlackRock, Inc. | $22.9M | 1,271,762 | 0.00% | 5q | +999.0%+$20.8M |
| TANG CAPITAL MANAGEMENT LLC | $20.9M | 1,160,000 | 0.95% | 5q | HELD |
| VANGUARD CAPITAL MANAGEMENT LLC | $13.8M | 767,755 | 0.00% | 2q | -4.2%-$605.5K |
| MILLENNIUM MANAGEMENT LLC | $7.3M | 403,859 | 0.00% | 3q | +24.8%+$1.4M |
| GEODE CAPITAL MANAGEMENT, LLC | $6.9M | 384,576 | 0.00% | 4q | +269.0%+$5.0M |
| JENNISON ASSOCIATES LLC | $6.8M | 378,507 | 0.00% | 2q | +147.4%+$4.1M |
| RTW INVESTMENTS, LP | $6.7M | 372,856 | 0.06% | 3q | HELD |
| NEXTBio Capital Management LP | $6.7M | 372,856 | 3.09% | 3q | HELD |
| Remedium Capital Partners, LLC | $6.5M | 361,250 | 1.44% | new | NEW |
| STATE STREET CORP | $5.7M | 315,587 | 0.00% | 4q | +707.8%+$5.0M |
| AMERIPRISE FINANCIAL INC | $5.4M | 302,568 | 0.00% | new | NEW |
| Point72 Asset Management, L.P. | $5.4M | 300,000 | 0.01% | 3q | HELD |
| MARSHALL WACE, LLP | $3.9M | 214,300 | 0.00% | 4q | +6.7%+$243.4K |
| PERCEPTIVE ADVISORS LLC | $3.7M | 206,942 | 0.06% | 5q | HELD |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $3.4M | 188,803 | 0.00% | new | NEW |
| TWO SIGMA INVESTMENTS, LP | $3.4M | 186,874 | 0.00% | 4q | +61.3%+$1.3M |
| STEMPOINT CAPITAL LP | $3.3M | 182,382 | 0.57% | new | NEW |
| UBS Group AG | $3.2M | 175,182 | 0.00% | 5q | +111.8%+$1.7M |
| NORTHERN TRUST CORP | $2.5M | 138,778 | 0.00% | 4q | +705.5%+$2.2M |
| Exome Asset Management LLC | $2.3M | 127,769 | 1.42% | 2q | -16.6%-$457.6K |
| SECTORAL ASSET MANAGEMENT INC | $2.2M | 121,300 | 1.52% | new | NEW |
| Woodline Partners LP | $1.7M | 94,488 | 0.01% | 3q | +27.7%+$368.8K |
| Stonepine Capital Management, LLC | $1.4M | 80,000 | 0.37% | 3q | -5.9%-$90.0K |
| VANGUARD FIDUCIARY TRUST CO | $1.4M | 75,225 | 0.00% | 2q | +52.2%+$464.4K |
| Burkehill Global Management, LP | $1.3M | 74,000 | 0.05% | 3q | HELD |
| Blackstone Inc. | $1.1M | 62,647 | 0.00% | new | NEW |
| SILVERARC CAPITAL MANAGEMENT, LLC | $1.1M | 59,104 | 0.11% | 2q | -54.7%-$1.3M |
| Y-Intercept (Hong Kong) Ltd | $914.8K | 50,824 | 0.02% | new | NEW |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $904.6K | 50,258 | 0.00% | new | NEW |
| Sixth Street Partners Management Company, L.P. | $904.6K | 50,258 | 0.00% | new | NEW |
| Nuveen, LLC | $857.3K | 47,629 | 0.00% | new | NEW |
| Bank of New York Mellon Corp | $824.0K | 45,778 | 0.00% | new | NEW |
| BANK OF AMERICA CORP /DE/ | $464.8K | 25,821 | 0.00% | 5q | -11.8%-$62.2K |
| RHUMBLINE ADVISERS | $458.8K | 25,487 | 0.00% | new | NEW |
| MOORE CAPITAL MANAGEMENT, LP | $450.0K | 25,000 | 0.01% | 3q | HELD |
| Squarepoint Ops LLC | $435.0K | 24,166 | 0.00% | new | NEW |
| AMERICAN CENTURY COMPANIES INC | $410.5K | 22,805 | 0.00% | new | NEW |
| WELLS FARGO & COMPANY/MN | $354.6K | 19,700 | 0.00% | new | NEW |
| ADAR1 Capital Management, LLC | $328.9K | 18,275 | 0.02% | 3q | -63.6%-$576.0K |
| Virtus Investment Advisers, LLC | $328.6K | 18,258 | 0.08% | new | NEW |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | $319.6K | 17,755 | 0.00% | 4q | -28.7%-$128.7K |
| MORGAN STANLEY | $318.6K | 17,698 | 0.00% | 5q | -4.7%-$15.8K |
| WELLINGTON MANAGEMENT GROUP LLP | $262.8K | 14,600 | 0.00% | new | NEW |
| BANK OF MONTREAL /CAN/ | $247.8K | 13,768 | 0.00% | new | NEW |
| MetLife Investment Management, LLC | $230.0K | 12,780 | 0.00% | new | NEW |
| Invesco Ltd. | $211.2K | 11,731 | 0.00% | new | NEW |
| Persistent Asset Partners Ltd | $197.4K | 10,968 | 0.06% | new | NEW |
| XTX Topco Ltd | $190.2K | 10,564 | 0.00% | new | NEW |
| CITIGROUP INC | $182.5K | 10,141 | 0.00% | 4q | -49.7%-$180.5K |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | $178.2K | 9,901 | 0.00% | new | NEW |
| JPMORGAN CHASE & CO | $162.4K | 9,020 | 0.00% | 4q | -78.0%-$575.7K |
| NEW YORK STATE COMMON RETIREMENT FUND | $136.8K | 7,600 | 0.00% | new | NEW |
| Police & Firemen's Retirement System of New Jersey | $114.6K | 6,369 | 0.00% | new | NEW |
| BARCLAYS PLC | $80.3K | 4,462 | 0.00% | 2q | -85.2%-$463.1K |
| BNP PARIBAS FINANCIAL MARKETS | $59.5K | 3,303 | 0.00% | 5q | -79.0%-$223.0K |
| Vanguard Global Advisers, LLC | $48.9K | 2,714 | 0.00% | 2q | -21.8%-$13.6K |
| Legal & General Group Plc | $37.7K | 2,097 | 0.00% | new | NEW |
| Tower Research Capital LLC (TRC) | $31.7K | 1,761 | 0.00% | new | NEW |
| Russell Investments Group, Ltd. | $31.1K | 1,726 | 0.00% | new | NEW |
| ROYAL BANK OF CANADA | $12.0K | 681 | 0.00% | 2q | +2096.8%+$11.5K |
| US BANCORP \DE\ | $7.3K | 403 | 0.00% | new | NEW |
| PRICE T ROWE ASSOCIATES INC /MD/ | $5.0K | 275,581 | 0.00% | 4q | -9.2% |
| Parallel Advisors, LLC | $4.8K | 264 | 0.00% | 2q | HELD |
| Allworth Financial LP | $2.9K | 161 | 0.00% | 2q | HELD |
| Sterling Capital Management LLC | $1.4K | 76 | 0.00% | new | NEW |
| SBI Securities Co., Ltd. | $1.2K | 68 | 0.00% | 5q | HELD |
| MERCER GLOBAL ADVISORS INC /ADV | $900 | 50 | 0.00% | new | NEW |
| Fortitude Family Office, LLC | $720 | 40 | 0.00% | 2q | HELD |
| Quarry LP | $522 | 29 | 0.00% | new | NEW |
| OSAIC HOLDINGS, INC. | $468 | 26 | 0.00% | 4q | HELD |
| Caitong International Asset Management Co., Ltd | $378 | 21 | 0.00% | 2q | +425.0% |
| NATIONAL BANK OF CANADA /FI/ | $54 | 3 | 0.00% | new | NEW |
Five percent filings
Anyone crossing 5% of a company must say so within days - far sooner than the next quarterly holdings report. A 13D declares an intent to influence the company; a 13G is the passive version. See all activist filings →
| Filed | Form | Filer | % of class |
|---|---|---|---|
| 2026-08-14 | 13G/A | BALYASNY ASSET MANAGEMENT L.P.with 4 co-filers | 6.0% |
| 2026-07-20 | 13D/A | Peter Harwin INDIVIDUALwith 3 co-filers | 16.5% |
Quarter by quarter
Coverage begins with the quarter ending 2018-12-31. Earlier filings exist only as occasional late amendments, too sparse to describe a market, so they are not shown.
| Quarter | Holders | Value | Shares | New | Added | Trimmed | Options |
|---|---|---|---|---|---|---|---|
| Q2 2026 | 80 | $520.7M | 28,928,248 | 33 | 17 | 13 | 0.0% |
| Q1 2026 | 59 | $455.7M | 24,823,929 | 15 | 16 | 7 | 0.0% |
| Q4 2025 | 52 | $277.3M | 23,390,590 | 18 | 16 | 7 | 0.0% |
| Q3 2025 | 39 | $130.0M | 10,935,287 | 14 | 6 | 8 | 0.0% |
| Q2 2025 | 29 | $173.5M | 10,751,740 | 29 | 0 | 0 | 0.0% |
| Q1 2025 | 1 | $170 | 22 | 1 | 0 | 0 | 0.0% |
| Q4 2024 | 1 | $182 | 15 | 1 | 0 | 0 | 0.0% |
| Q4 2023 | 1 | $1.7K | 66 | 1 | 0 | 0 | 0.0% |
| Q3 2023 | 27 | $745.3K | 1,457,903 | 5 | 5 | 6 | 5.6% |
| Q2 2023 | 24 | $471.7K | 1,263,495 | 5 | 3 | 6 | 5.8% |
| Q1 2023 | 26 | $394.1K | 1,747,777 | 2 | 8 | 5 | 4.7% |
| Q4 2022 | 25 | $1.6M | 3,044,941 | 7 | 2 | 6 | 2.4% |
| Q3 2022 | 35 | $5.2M | 7,734,424 | 3 | 8 | 9 | 25.0% |
| Q2 2022 | 40 | $20.9M | 8,034,517 | 7 | 3 | 15 | 32.0% |
| Q1 2022 | 45 | $6.6M | 9,682,236 | 2 | 6 | 20 | 2.5% |
| Q4 2021 | 51 | $14.3M | 15,118,809 | 11 | 12 | 13 | 3.1% |
| Q3 2021 | 68 | $80.9M | 18,384,844 | 13 | 7 | 30 | 6.4% |
| Q2 2021 | 72 | $89.6M | 20,239,985 | 10 | 17 | 30 | 2.1% |
| Q1 2021 | 92 | $116.5M | 22,426,246 | 22 | 38 | 18 | 3.0% |
| Q4 2020 | 82 | $92.8M | 14,380,290 | 16 | 29 | 17 | 2.2% |
| Q3 2020 | 79 | $60.9M | 14,095,053 | 9 | 33 | 20 | 0.5% |
| Q2 2020 | 79 | $83.7M | 14,018,278 | 37 | 21 | 16 | 1.7% |
| Q1 2020 | 45 | $48.0M | 10,757,534 | 13 | 16 | 11 | 2.0% |
| Q4 2019 | 45 | $52.4M | 7,659,600 | 11 | 12 | 16 | 0.4% |
| Q3 2019 | 40 | $36.6M | 7,443,807 | 8 | 11 | 15 | 0.1% |
| Q2 2019 | 49 | $56.9M | 7,671,438 | 11 | 19 | 16 | 0.6% |
| Q1 2019 | 62 | $67.8M | 8,230,666 | 7 | 22 | 24 | 1.6% |
| Q4 2018 | 65 | $60.8M | 7,584,410 | 3 | 0 | 2 | 1.6% |