AXSOME THERAPEUTICS INC (AXSM)
Institutional ownership reported to the SEC as of Q2 2026, across 31 quarters.
488
Reporting holders
$9.8B
Reported value
72.5%
Of shares outstanding
5.4%
Held as options
+92
Holder change
Institutions report 37,989,770 shares against 52,380,818 outstanding. Shares only - option lines are excluded, which is why this can be compared with the company at all. The count comes from the cover page of the company's own most recent report, so it is dated when that was filed rather than at quarter end.
Options share is the part of reported value carried in derivative lines rather than shares. A high figure means institutions are expressing a view on this security without owning much of it.
Holders
| Filer | Value | Shares | Their book | Held | Change |
|---|---|---|---|---|---|
| BlackRock, Inc. | $759.7M | 3,103,708 | 0.01% | 8q | -20.7%-$198.1M |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $485.5M | 1,983,514 | 0.02% | 2q | -3.6%-$18.3M |
| VANGUARD CAPITAL MANAGEMENT LLC | $481.0M | 1,965,086 | 0.01% | 2q | +1.4%+$6.7M |
| Invesco Ltd. | $409.2M | 1,671,684 | 0.03% | 30q | +28.8%+$91.5M |
| FMR LLC | $376.7M | 1,539,163 | 0.02% | 28q | -1.8%-$6.8M |
| GEODE CAPITAL MANAGEMENT, LLC | $236.8M | 967,172 | 0.01% | 31q | -16.8%-$47.9M |
| Assenagon Asset Management S.A. | $222.6M | 909,364 | 0.14% | 9q | +5.0%+$10.6M |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $222.1M | 87,815 | 0.02% | 31q | +86.1%+$102.7M |
| MORGAN STANLEY | $196.8M | 804,082 | 0.01% | 35q | +68.7%+$80.1M |
| STATE STREET CORP | $192.3M | 785,661 | 0.01% | 30q | -20.4%-$49.2M |
| JANE STREET GROUP, LLC | $183.5M | 403,995 | 0.02% | 30q | +9806.7%+$181.7M |
| Deep Track Capital, LP | $171.3M | 700,000 | 2.49% | 5q | -36.4%-$97.9M |
| TWO SIGMA INVESTMENTS, LP | $166.4M | 669,478 | 0.12% | 4q | +107.4%+$86.2M |
| FRANKLIN RESOURCES INC | $163.6M | 668,373 | 0.04% | 15q | +52.4%+$56.3M |
| WELLINGTON MANAGEMENT GROUP LLP | $160.1M | 653,920 | 0.03% | 13q | -42.9%-$120.3M |
| D. E. Shaw & Co., Inc. | $159.9M | 604,753 | 0.08% | 15q | HELD |
| ALETHEA CAPITAL MANAGEMENT, LLC | $158.8M | 648,756 | 65.78% | 31q | HELD |
| MILLENNIUM MANAGEMENT LLC | $139.8M | 556,088 | 0.05% | 14q | +2578.9%+$134.6M |
| NOMURA ASSET MANAGEMENT INTERNATIONAL INC. | $132.0M | 539,407 | 0.20% | 3q | -33.6%-$66.9M |
| CITADEL ADVISORS LLC | $126.1M | 255,878 | 0.01% | 30q | -9.1%-$12.6M |
| NORGES BANK | $125.9M | 514,266 | 0.01% | 24q | +3.8%+$4.6M |
| FIRST TRUST ADVISORS LP | $118.0M | 482,061 | 0.07% | 11q | -16.5%-$23.4M |
| Point72 Asset Management, L.P. | $117.4M | 416,516 | 0.13% | 17q | -1.9%-$2.3M |
| BANK OF AMERICA CORP /DE/ | $110.8M | 452,491 | 0.01% | 29q | -24.3%-$35.6M |
| AMERIPRISE FINANCIAL INC | $104.8M | 428,079 | 0.02% | 16q | +21.4%+$18.5M |
| Pictet Asset Management Holding SA | $104.4M | 426,527 | 0.10% | 12q | +2.5%+$2.6M |
| Qube Research & Technologies Ltd | $104.4M | 426,336 | 0.10% | 8q | +27.1%+$22.3M |
| Hood River Capital Management LLC | $98.6M | 402,678 | 0.71% | 5q | +8.4%+$7.6M |
| HEALTHCARE OF ONTARIO PENSION PLAN TRUST FUND | $91.3M | 373,067 | 0.13% | 2q | +282.4%+$67.4M |
| Driehaus Capital Management LLC | $91.2M | 372,474 | 0.53% | 6q | +27.4%+$19.6M |
| PRINCIPAL FINANCIAL GROUP INC | $81.4M | 332,642 | 0.04% | 18q | -5.1%-$4.4M |
| EVENTIDE ASSET MANAGEMENT, LLC | $77.5M | 316,820 | 1.04% | 12q | -39.0%-$49.6M |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $77.4M | 316,104 | 0.01% | 29q | -20.0%-$19.3M |
| Sixth Street Partners Management Company, L.P. | $77.4M | 316,104 | 0.01% | new | NEW |
| Integral Health Asset Management, LLC | $73.4M | 300,000 | 2.90% | 2q | +757.1%+$64.9M |
| VANGUARD FIDUCIARY TRUST CO | $68.5M | 279,738 | 0.02% | 2q | -5.2%-$3.8M |
| NORTHERN TRUST CORP | $66.1M | 270,189 | 0.01% | 31q | -32.7%-$32.1M |
| RENAISSANCE TECHNOLOGIES LLC | $64.1M | 262,000 | 0.09% | 6q | +59.5%+$23.9M |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | $63.4M | 259,034 | 0.09% | 18q | -64.9%-$117.1M |
| FRONTIER CAPITAL MANAGEMENT CO LLC | $62.2M | 254,280 | 0.58% | 15q | +25.2%+$12.5M |
| SAMLYN CAPITAL, LLC | $60.2M | 246,015 | 0.98% | new | NEW |
| Clearbridge Investments, LLC | $60.1M | 245,574 | 0.05% | 10q | +445.5%+$49.1M |
| LOOMIS SAYLES & CO L P | $58.6M | 239,490 | 0.07% | 10q | -6.7%-$4.2M |
| Public Sector Pension Investment Board | $56.8M | 232,000 | 0.07% | new | NEW |
| BNP PARIBAS FINANCIAL MARKETS | $56.5M | 230,954 | 0.02% | 31q | +22.8%+$10.5M |
| GOLDMAN SACHS GROUP INC | $56.2M | 229,668 | 0.00% | 30q | -45.5%-$46.9M |
| CANADA PENSION PLAN INVESTMENT BOARD | $55.2M | 225,400 | 0.03% | 7q | +146.6%+$32.8M |
| MARSHALL WACE, LLP | $54.7M | 223,386 | 0.04% | 7q | +58.2%+$20.1M |
| PFM Health Sciences, LP | $53.8M | 219,596 | 4.61% | 17q | -16.9%-$10.9M |
| Tri Locum Partners LP | $53.7M | 219,308 | 6.60% | 15q | +253.1%+$38.5M |
| First Turn Management, LLC | $53.5M | 218,415 | 5.72% | 11q | +15.7%+$7.3M |
| GROUP ONE TRADING LLC | $49.9M | options only | 0.07% | 31q | OPTIONS |
| Bank of New York Mellon Corp | $48.3M | 197,226 | 0.01% | 31q | -4.6%-$2.3M |
| Nuveen, LLC | $46.5M | 190,080 | 0.01% | 6q | -43.4%-$35.7M |
| FEDERATED HERMES, INC. | $43.5M | 177,842 | 0.06% | 6q | +63.8%+$17.0M |
| Woodline Partners LP | $39.7M | 162,221 | 0.12% | 15q | HELD |
| JPMORGAN CHASE & CO | $39.5M | 162,065 | 0.00% | 29q | -40.0%-$26.4M |
| Sofinnova Investments, Inc. | $39.3M | 160,429 | 2.03% | 9q | -24.6%-$12.8M |
| Squarepoint Ops LLC | $38.3M | 154,605 | 0.04% | 8q | +35.5%+$10.0M |
| NEUBERGER BERMAN GROUP LLC | $38.3M | 156,523 | 0.03% | 5q | +157.6%+$23.4M |
| RAYMOND JAMES FINANCIAL INC | $38.1M | 155,855 | 0.01% | 7q | +5.5%+$2.0M |
| UBS Group AG | $37.2M | 151,903 | 0.00% | 30q | -72.2%-$96.8M |
| WESTFIELD CAPITAL MANAGEMENT CO LP | $35.5M | 145,145 | 0.12% | new | NEW |
| VOYA INVESTMENT MANAGEMENT LLC | $34.8M | 142,051 | 0.03% | 27q | -22.8%-$10.3M |
| CITIGROUP INC | $33.5M | 136,858 | 0.01% | 30q | -26.3%-$11.9M |
| ARROWSTREET CAPITAL, LIMITED PARTNERSHIP | $33.1M | 135,195 | 0.01% | new | NEW |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | $31.1M | 127,178 | 0.01% | 29q | +34.0%+$7.9M |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | $29.1M | 118,999 | 0.02% | 29q | +1.6%+$466.5K |
| PERCEPTIVE ADVISORS LLC | $29.0M | 118,450 | 0.44% | 13q | -21.0%-$7.7M |
| ORBIMED ADVISORS LLC | $28.8M | 117,578 | 0.53% | 6q | -45.0%-$23.6M |
| AQR CAPITAL MANAGEMENT LLC | $27.9M | 114,025 | 0.01% | 17q | +9.6%+$2.4M |
| Caption Management, LLC | $27.8M | options only | 0.13% | 8q | OPTIONS |
| EMERALD ADVISERS, LLC | $25.5M | 104,237 | 0.60% | 5q | -3.1%-$825.6K |
| Nicholas Investment Partners, LP | $24.2M | 98,974 | 1.36% | 8q | +21.5%+$4.3M |
| Connor, Clark & Lunn Investment Management Ltd. | $23.9M | 97,698 | 0.05% | 7q | -27.5%-$9.1M |
| ALGERT GLOBAL LLC | $23.3M | 95,335 | 0.28% | 6q | -64.8%-$43.0M |
| ROYCE & ASSOCIATES LP | $22.3M | 91,041 | 0.18% | 10q | -3.2%-$728.4K |
| MetLife Investment Management, LLC | $21.9M | 89,662 | 0.10% | 29q | -41.3%-$15.4M |
| DEUTSCHE BANK AG\ | $21.2M | 86,466 | 0.01% | 29q | -17.1%-$4.4M |
| Voleon Capital Management LP | $20.7M | 84,433 | 0.38% | 4q | -42.9%-$15.5M |
| Cannell & Spears LLC | $20.6M | 84,154 | 0.37% | 10q | HELD |
| Trexquant Investment LP | $20.5M | 83,679 | 0.12% | 4q | +1309.9%+$19.0M |
| Man Group plc | $20.2M | 82,526 | 0.03% | 7q | -42.0%-$14.6M |
| Granite Investment Partners, LLC | $19.6M | 80,124 | 1.00% | 7q | HELD |
| Weiss Asset Management LP | $19.6M | 80,000 | 0.21% | new | NEW |
| Swiss National Bank | $19.5M | 79,500 | 0.01% | 29q | +15.1%+$2.5M |
| Aberdeen Group plc | $19.1M | 78,236 | 0.03% | 9q | -47.7%-$17.5M |
| SEI INVESTMENTS CO | $18.7M | 76,462 | 0.02% | 30q | +9.1%+$1.6M |
| Balyasny Asset Management L.P. | $18.7M | 76,250 | 0.02% | new | NEW |
| California Public Employees Retirement System | $18.3M | 74,778 | 0.01% | 2q | +47.0%+$5.8M |
| WCM INVESTMENT MANAGEMENT, LLC | $18.3M | 75,713 | 0.03% | 26q | -29.8%-$7.7M |
| SIMPLEX TRADING, LLC | $18.0M | 19,643 | 0.01% | 22q | HELD |
| Science & Technology Partners, L.P. | $17.9M | 73,040 | 3.01% | new | NEW |
| TimesSquare Capital Management, LLC | $17.5M | 71,510 | 0.26% | new | NEW |
| IMC-Chicago, LLC | $16.9M | 10,187 | 0.00% | 4q | +29.8%+$3.9M |
| EMERALD MUTUAL FUND ADVISERS TRUST | $16.4M | 67,195 | 0.58% | 5q | HELD |
| US BANCORP \DE\ | $16.3M | 66,580 | 0.02% | 29q | -49.3%-$15.9M |
| DNB Asset Management AS | $16.0M | 65,199 | 0.04% | 10q | -27.6%-$6.1M |
| Eagle Health Investments LP | $15.9M | 65,051 | 2.64% | new | NEW |
| Universal- Beteiligungs- und Servicegesellschaft mbH | $15.6M | 63,551 | 0.02% | 6q | -10.1%-$1.8M |
Five percent filings
Anyone crossing 5% of a company must say so within days - far sooner than the next quarterly holdings report. A 13D declares an intent to influence the company; a 13G is the passive version. See all activist filings →
| Filed | Form | Filer | % of class |
|---|---|---|---|
| 2026-07-27 | 13G/A | BlackRock, Inc. | 5.3% |
Quarter by quarter
Coverage begins with the quarter ending 2018-12-31. Earlier filings exist only as occasional late amendments, too sparse to describe a market, so they are not shown.
| Quarter | Holders | Value | Shares | New | Added | Trimmed | Options |
|---|---|---|---|---|---|---|---|
| Q2 2026 | 488 | $9.8B | 37,989,770 | 125 | 143 | 142 | 5.4% |
| Q1 2026 | 396 | $6.5B | 36,870,657 | 63 | 133 | 123 | 3.8% |
| Q4 2025 | 378 | $6.8B | 36,088,425 | 62 | 126 | 115 | 4.1% |
| Q3 2025 | 340 | $4.5B | 36,094,093 | 45 | 131 | 98 | 3.5% |
| Q2 2025 | 334 | $4.0B | 37,019,141 | 51 | 140 | 81 | 3.2% |
| Q1 2025 | 328 | $4.5B | 36,888,145 | 79 | 96 | 104 | 4.2% |
| Q4 2024 | 281 | $3.3B | 36,221,110 | 53 | 83 | 75 | 8.3% |
| Q3 2024 | 261 | $3.6B | 38,299,996 | 42 | 72 | 86 | 4.9% |
| Q2 2024 | 239 | $3.3B | 40,467,065 | 29 | 71 | 83 | 2.7% |
| Q1 2024 | 238 | $3.3B | 40,368,401 | 37 | 88 | 64 | 3.3% |
| Q4 2023 | 224 | $3.2B | 39,075,498 | 29 | 62 | 76 | 3.6% |
| Q3 2023 | 209 | $2.7B | 37,686,137 | 16 | 75 | 63 | 3.3% |
| Q2 2023 | 217 | $2.7B | 35,741,541 | 45 | 79 | 50 | 5.8% |
| Q1 2023 | 178 | $2.0B | 31,061,962 | 17 | 60 | 58 | 6.0% |
| Q4 2022 | 193 | $2.4B | 28,132,664 | 51 | 48 | 59 | 11.5% |
| Q3 2022 | 193 | $1.4B | 25,729,739 | 48 | 63 | 46 | 16.5% |
| Q2 2022 | 179 | $1.0B | 21,592,119 | 31 | 65 | 39 | 20.7% |
| Q1 2022 | 179 | $952.6M | 19,120,961 | 30 | 38 | 63 | 16.8% |
| Q4 2021 | 170 | $923.0M | 18,840,165 | 20 | 48 | 58 | 22.9% |
| Q3 2021 | 169 | $733.6M | 19,063,155 | 36 | 66 | 38 | 14.5% |
| Q2 2021 | 173 | $1.6B | 22,922,004 | 19 | 62 | 49 | 5.4% |
| Q1 2021 | 185 | $1.4B | 23,053,635 | 34 | 61 | 50 | 4.9% |
| Q4 2020 | 180 | $2.1B | 24,063,600 | 18 | 63 | 54 | 6.1% |
| Q3 2020 | 174 | $1.8B | 24,039,492 | 21 | 45 | 71 | 6.1% |
| Q2 2020 | 193 | $2.1B | 24,274,052 | 55 | 67 | 50 | 5.7% |
| Q1 2020 | 171 | $1.5B | 22,878,707 | 47 | 61 | 42 | 11.8% |
| Q4 2019 | 177 | $2.7B | 22,744,536 | 68 | 41 | 48 | 13.8% |
| Q3 2019 | 115 | $432.9M | 18,920,865 | 26 | 44 | 23 | 10.5% |
| Q2 2019 | 112 | $540.2M | 18,432,791 | 59 | 25 | 20 | 11.4% |
| Q1 2019 | 67 | $250.0M | 14,817,945 | 40 | 12 | 10 | 13.7% |
| Q4 2018 | 36 | $11.4M | 3,920,871 | 2 | 0 | 1 | 3.0% |