ORUKA THERAPEUTICS INC (ORKA)
Institutional ownership reported to the SEC as of Q2 2026, across 8 quarters.
249
Reporting holders
$6.9B
Reported value
108.9%
Of shares outstanding
0.5%
Held as options
+66
Holder change
Institutions report 72,074,735 shares against 66,209,699 outstanding. Shares only - option lines are excluded, which is why this can be compared with the company at all. The count comes from the cover page of the company's own most recent report, so it is dated when that was filed rather than at quarter end. Over 100% because an adviser and a sub-adviser can both report the same shares, and both are counted.
Options share is the part of reported value carried in derivative lines rather than shares. A high figure means institutions are expressing a view on this security without owning much of it.
Holders
| Filer | Value | Shares | Their book | Held | Change |
|---|---|---|---|---|---|
| FMR LLC | $862.0M | 9,057,645 | 0.04% | 8q | +21.9%+$154.8M |
| BlackRock, Inc. | $474.9M | 4,990,181 | 0.01% | 8q | +41.5%+$139.2M |
| Venrock Adviser, LLC | $394.8M | 4,148,428 | 11.97% | 8q | HELD |
| Fairmount Funds Management LLC | $352.6M | 3,705,262 | 23.31% | 8q | HELD |
| Capital World Investors | $323.7M | 3,401,639 | 0.04% | new | NEW |
| RTW INVESTMENTS, LP | $298.7M | 3,139,030 | 2.55% | 8q | +52.5%+$102.9M |
| STATE STREET CORP | $254.4M | 2,673,090 | 0.01% | 7q | +65.7%+$100.8M |
| VANGUARD CAPITAL MANAGEMENT LLC | $224.7M | 2,360,971 | 0.00% | 2q | +27.0%+$47.7M |
| Paradigm Biocapital Advisors LP | $204.1M | 2,144,526 | 3.82% | 3q | -7.6%-$16.7M |
| Deep Track Capital, LP | $183.3M | 1,926,000 | 2.67% | 8q | -5.3%-$10.3M |
| Bellevue Group AG | $157.7M | 1,657,190 | 3.32% | 2q | +226.9%+$109.5M |
| FRANKLIN RESOURCES INC | $154.3M | 1,621,451 | 0.03% | 8q | +61.5%+$58.8M |
| Remedium Capital Partners, LLC | $149.0M | 1,565,661 | 32.99% | 3q | HELD |
| RA CAPITAL MANAGEMENT, L.P. | $148.0M | 1,554,597 | 1.29% | new | NEW |
| VIKING GLOBAL INVESTORS LP | $143.1M | 1,503,478 | 0.41% | 4q | -43.6%-$110.7M |
| GEODE CAPITAL MANAGEMENT, LLC | $136.1M | 1,429,954 | 0.01% | 8q | +49.8%+$45.2M |
| Jupiter Topco LLC | $131.0M | 1,375,844 | 0.05% | new | FIRST |
| PERCEPTIVE ADVISORS LLC | $128.0M | 1,345,063 | 1.92% | 4q | -3.6%-$4.8M |
| Polar Capital Holdings Plc | $116.9M | 1,228,609 | 0.28% | 7q | +17.3%+$17.2M |
| CITADEL ADVISORS LLC | $109.7M | 1,119,011 | 0.01% | 4q | +11.1%+$10.9M |
| BNP PARIBAS FINANCIAL MARKETS | $102.7M | 1,079,015 | 0.04% | 7q | +9773.9%+$101.6M |
| Avidity Partners Management LP | $72.4M | 760,424 | 11.59% | 8q | -50.0%-$72.4M |
| SUMMIT PARTNERS PUBLIC ASSET MANAGEMENT, LLC | $62.7M | 658,301 | 1.10% | new | NEW |
| Aberdeen Group plc | $61.6M | 646,943 | 0.09% | 5q | +754.8%+$54.4M |
| UBS Group AG | $60.8M | 639,363 | 0.01% | 7q | +201.2%+$40.6M |
| JPMORGAN CHASE & CO | $60.7M | 655,027 | 0.00% | 7q | +2795.8%+$58.6M |
| WESTFIELD CAPITAL MANAGEMENT CO LP | $60.1M | 631,433 | 0.20% | 2q | +101.7%+$30.3M |
| Pictet Asset Management Holding SA | $58.9M | 619,076 | 0.06% | new | NEW |
| Affinity Asset Advisors, LLC | $56.2M | 590,000 | 2.54% | 8q | +18.1%+$8.6M |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $55.4M | 582,409 | 0.00% | 2q | +66.0%+$22.0M |
| Cormorant Asset Management, LP | $50.8M | 533,340 | 2.60% | 4q | HELD |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $41.2M | 433,405 | 0.01% | 7q | +34.6%+$10.6M |
| Sixth Street Partners Management Company, L.P. | $41.2M | 433,405 | 0.01% | new | NEW |
| NORTHERN TRUST CORP | $40.8M | 428,891 | 0.00% | 7q | +43.4%+$12.4M |
| VOYA INVESTMENT MANAGEMENT LLC | $38.2M | 401,149 | 0.03% | 3q | +502.3%+$31.8M |
| VANGUARD FIDUCIARY TRUST CO | $34.8M | 365,630 | 0.01% | 2q | +42.2%+$10.3M |
| MASSACHUSETTS FINANCIAL SERVICES CO /MA/ | $34.7M | 364,102 | 0.01% | new | NEW |
| Synergy Asset Management, LLC | $33.9M | 356,301 | 3.20% | 3q | -25.2%-$11.4M |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | $33.8M | 355,003 | 0.05% | 2q | +86.8%+$15.7M |
| BANK OF AMERICA CORP /DE/ | $33.6M | 352,824 | 0.00% | 8q | +252.5%+$24.1M |
| SILVERARC CAPITAL MANAGEMENT, LLC | $33.6M | 352,802 | 3.49% | 2q | +133.8%+$19.2M |
| Candriam S.C.A. | $33.5M | 352,716 | 0.15% | 6q | -14.2%-$5.5M |
| Holocene Advisors, LP | $29.1M | 305,951 | 0.07% | 2q | +64.9%+$11.5M |
| JENNISON ASSOCIATES LLC | $28.5M | 299,257 | 0.02% | 2q | +69.4%+$11.7M |
| Woodline Partners LP | $27.1M | 285,247 | 0.08% | 8q | -50.4%-$27.6M |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $26.6M | 4,588 | 0.00% | 6q | -78.1%-$95.2M |
| BRAIDWELL LP | $26.5M | 278,164 | 0.98% | new | NEW |
| Siren, L.L.C. | $23.8M | 250,000 | 0.48% | new | NEW |
| Nuveen, LLC | $23.7M | 249,267 | 0.01% | 5q | +186.7%+$15.4M |
| EVENTIDE ASSET MANAGEMENT, LLC | $22.8M | 240,000 | 0.31% | new | NEW |
| Blackstone Inc. | $22.6M | 237,108 | 0.07% | new | NEW |
| NOMURA ASSET MANAGEMENT INTERNATIONAL INC. | $20.8M | 219,039 | 0.03% | new | NEW |
| SEB Asset Management AB | $18.7M | 196,753 | 0.07% | new | NEW |
| DEUTSCHE BANK AG\ | $18.6M | 195,204 | 0.01% | 5q | +38.7%+$5.2M |
| GREAT POINT PARTNERS LLC | $17.4M | 183,330 | 3.30% | 4q | HELD |
| GOLDMAN SACHS GROUP INC | $17.1M | 179,439 | 0.00% | 6q | -27.3%-$6.4M |
| Sio Capital Management, LLC | $16.9M | 177,118 | 2.79% | 3q | +33.7%+$4.2M |
| PFM Health Sciences, LP | $15.1M | 158,825 | 1.30% | 2q | -8.7%-$1.4M |
| First Turn Management, LLC | $14.8M | 155,343 | 1.58% | new | NEW |
| ExodusPoint Capital Management, LP | $14.1M | 148,212 | 0.09% | 2q | +46.2%+$4.5M |
| Bank of New York Mellon Corp | $13.4M | 140,870 | 0.00% | 5q | +31.8%+$3.2M |
| Invesco Ltd. | $11.9M | 124,658 | 0.00% | 5q | +28.5%+$2.6M |
| VICTORY CAPITAL MANAGEMENT INC | $11.8M | 124,278 | 0.01% | 2q | +2556.6%+$11.4M |
| WELLINGTON MANAGEMENT GROUP LLP | $11.4M | 119,601 | 0.00% | 4q | -1.3%-$154.6K |
| STEMPOINT CAPITAL LP | $11.1M | 116,461 | 1.91% | new | NEW |
| Parkman Healthcare Partners LLC | $10.8M | 113,188 | 1.10% | new | NEW |
| DIMENSIONAL FUND ADVISORS LP | $10.8M | 113,176 | 0.00% | 2q | HELD |
| Russell Investments Group, Ltd. | $10.7M | 112,943 | 0.01% | 4q | +148.5%+$6.4M |
| Apis Capital Advisors, LLC | $10.7M | 112,000 | 1.04% | new | NEW |
| SEVEN GRAND MANAGERS, LLC | $10.5M | 110,000 | 0.42% | new | NEW |
| KENNEDY CAPITAL MANAGEMENT LLC | $10.2M | 106,863 | 0.18% | 7q | -15.4%-$1.9M |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | $9.9M | 104,310 | 0.00% | 3q | +517.1%+$8.3M |
| TD Asset Management Inc | $9.8M | 102,944 | 0.01% | 8q | +36.0%+$2.6M |
| Moody Aldrich Partners LLC | $9.7M | 101,411 | 1.73% | 3q | -24.9%-$3.2M |
| Palo Alto Investors LP | $9.6M | 100,638 | 0.44% | 4q | +67.8%+$3.9M |
| Atika Capital Management LLC | $9.5M | 100,000 | 0.63% | 2q | -56.5%-$12.4M |
| TORONTO DOMINION BANK | $8.5M | 89,837 | 0.01% | new | NEW |
| Alyeska Investment Group, L.P. | $8.4M | 87,744 | 0.02% | 3q | -52.5%-$9.2M |
| PRUDENTIAL FINANCIAL INC | $8.2M | 85,895 | 0.01% | 2q | +1322.1%+$7.6M |
| Rhenman & Partners Asset Management AB | $7.6M | 80,000 | 0.72% | new | NEW |
| MORGAN STANLEY | $7.3M | 76,360 | 0.00% | 8q | -56.5%-$9.4M |
| B Group, Inc. | $7.1M | 75,000 | 3.35% | 7q | HELD |
| BARCLAYS PLC | $7.1M | 74,762 | 0.00% | 7q | -12.8%-$1.0M |
| AMERIPRISE FINANCIAL INC | $6.9M | 72,734 | 0.00% | new | NEW |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | $6.5M | 68,421 | 0.01% | 8q | -5.7%-$394.2K |
| Fisher Asset Management, LLC | $6.5M | 67,874 | 0.00% | new | NEW |
| Ensign Peak Advisors, Inc | $6.4M | 67,668 | 0.01% | 2q | -57.4%-$8.7M |
| CITIGROUP INC | $6.4M | 67,101 | 0.00% | 8q | +546.0%+$5.4M |
| Secure Asset Management, LLC | $6.3M | 65,899 | 0.88% | 3q | -9.0%-$620.8K |
| Swiss National Bank | $6.0M | 63,000 | 0.00% | 3q | +46.5%+$1.9M |
| ALPS ADVISORS INC | $5.8M | 61,014 | 0.03% | 3q | +54.8%+$2.1M |
| RHUMBLINE ADVISERS | $5.8M | 60,784 | 0.00% | 5q | +31.1%+$1.4M |
| Informed Momentum Co LLC | $5.6M | 59,014 | 0.50% | 2q | -1.6%-$88.7K |
| Atle Fund Management AB | $5.2M | 54,886 | 1.41% | new | NEW |
| WELLS FARGO & COMPANY/MN | $4.9M | 51,924 | 0.00% | 5q | +75.1%+$2.1M |
| Granahan Investment Management, LLC | $4.9M | 51,038 | 0.17% | new | NEW |
| Ghisallo Capital Management LLC | $4.8M | 50,000 | 0.09% | new | NEW |
| Burkehill Global Management, LP | $4.8M | 50,000 | 0.17% | new | NEW |
| Trexquant Investment LP | $4.7M | 49,616 | 0.03% | new | NEW |
| Rafferty Asset Management, LLC | $4.1M | 43,110 | 0.01% | 4q | +6.5%+$249.6K |
Five percent filings
Anyone crossing 5% of a company must say so within days - far sooner than the next quarterly holdings report. A 13D declares an intent to influence the company; a 13G is the passive version. See all activist filings →
| Filed | Form | Filer | % of class |
|---|---|---|---|
| 2026-08-14 | 13G/A | VIKING GLOBAL INVESTORS LPwith 9 co-filers | 2.5% |
| 2026-08-14 | 13G/A | Venrock Healthcare Capital Partners III, L.P.with 6 co-filers | 7.4% |
| 2026-08-14 | 13G | RTW Investments, LPwith 1 co-filers | 5.2% |
| 2026-08-12 | 13G | Capital World Investors | 5.6% |
| 2026-07-01 | 13D/A | Harwin Peter Evan INDIVIDUALwith 4 co-filers | 19.5% |
Quarter by quarter
Coverage begins with the quarter ending 2018-12-31. Earlier filings exist only as occasional late amendments, too sparse to describe a market, so they are not shown.
| Quarter | Holders | Value | Shares | New | Added | Trimmed | Options |
|---|---|---|---|---|---|---|---|
| Q2 2026 | 249 | $6.9B | 72,074,735 | 93 | 89 | 48 | 0.5% |
| Q1 2026 | 183 | $2.6B | 52,271,607 | 56 | 61 | 30 | 0.3% |
| Q4 2025 | 138 | $1.5B | 50,639,804 | 38 | 49 | 17 | 0.1% |
| Q3 2025 | 103 | $867.3M | 44,942,944 | 34 | 28 | 22 | 0.4% |
| Q2 2025 | 79 | $381.4M | 34,019,603 | 25 | 24 | 13 | 0.0% |
| Q1 2025 | 67 | $321.0M | 31,282,394 | 16 | 28 | 8 | 0.0% |
| Q4 2024 | 64 | $580.9M | 29,711,302 | 25 | 18 | 8 | 0.0% |
| Q3 2024 | 43 | $597.9M | 24,279,855 | 43 | 0 | 0 | 0.1% |