ALTO NEUROSCIENCE INC (ANRO)
Institutional ownership reported to the SEC as of Q2 2026, across 10 quarters.
117
Reporting holders
$771.6M
Reported value
74.3%
Of shares outstanding
0.4%
Held as options
+8
Holder change
Institutions report 29,139,515 shares against 39,242,104 outstanding. Shares only - option lines are excluded, which is why this can be compared with the company at all. The count comes from the cover page of the company's own most recent report, so it is dated when that was filed rather than at quarter end.
Options share is the part of reported value carried in derivative lines rather than shares. A high figure means institutions are expressing a view on this security without owning much of it.
Holders
| Filer | Value | Shares | Their book | Held | Change |
|---|---|---|---|---|---|
| Alpha Wave Global, LP | $97.8M | 3,707,757 | 1.57% | 10q | HELD |
| Commodore Capital LP | $71.9M | 2,723,196 | 4.28% | 3q | HELD |
| BlackRock, Inc. | $56.0M | 2,121,009 | 0.00% | 8q | +218.4%+$38.4M |
| PERCEPTIVE ADVISORS LLC | $42.5M | 1,609,893 | 0.64% | 4q | -19.9%-$10.6M |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | $42.2M | 1,600,000 | 0.06% | 2q | +315.6%+$32.1M |
| VANGUARD CAPITAL MANAGEMENT LLC | $36.7M | 1,389,477 | 0.00% | 2q | +15.1%+$4.8M |
| Spruce Street Capital LP | $35.7M | 1,353,047 | 7.01% | 3q | +2.1%+$734.6K |
| Vivo Capital, LLC | $31.9M | 1,208,858 | 2.91% | 3q | +16.7%+$4.6M |
| FRANKLIN RESOURCES INC | $26.7M | 1,013,307 | 0.01% | 10q | -8.0%-$2.3M |
| ARMISTICE CAPITAL, LLC | $22.8M | 864,000 | 0.28% | 7q | -5.3%-$1.3M |
| Affinity Asset Advisors, LLC | $22.4M | 850,000 | 1.01% | 2q | +70.0%+$9.2M |
| Vestal Point Capital, LP | $20.7M | 785,000 | 0.48% | 10q | -62.0%-$33.8M |
| STATE STREET CORP | $18.1M | 685,945 | 0.00% | 10q | +243.8%+$12.8M |
| GEODE CAPITAL MANAGEMENT, LLC | $17.9M | 678,199 | 0.00% | 10q | +131.5%+$10.2M |
| 72 Investment Holdings, LLC | $17.6M | 667,778 | 35.27% | 10q | HELD |
| NORTHERN TRUST CORP | $16.7M | 632,701 | 0.00% | 10q | +33.6%+$4.2M |
| MILLENNIUM MANAGEMENT LLC | $14.7M | 558,320 | 0.01% | 6q | -32.1%-$7.0M |
| Point72 Asset Management, L.P. | $13.3M | 502,950 | 0.01% | 10q | HELD |
| Venrock Adviser, LLC | $13.2M | 500,000 | 0.40% | 2q | HELD |
| Integral Health Asset Management, LLC | $13.2M | 500,000 | 0.52% | 7q | HELD |
| Driehaus Capital Management LLC | $12.9M | 487,576 | 0.07% | 3q | HELD |
| Parkman Healthcare Partners LLC | $11.3M | 429,035 | 1.16% | new | NEW |
| Ikarian Capital, LLC | $10.7M | 407,338 | 1.16% | 8q | -20.9%-$2.8M |
| ORBIMED ADVISORS LLC | $6.8M | 257,852 | 0.13% | 7q | +53.9%+$2.4M |
| Schonfeld Strategic Advisors LLC | $6.8M | 257,631 | 0.02% | new | NEW |
| GOLDMAN SACHS GROUP INC | $6.2M | 236,830 | 0.00% | 9q | +126.2%+$3.5M |
| MARSHALL WACE, LLP | $6.0M | 225,503 | 0.00% | 7q | +27.9%+$1.3M |
| VANGUARD FIDUCIARY TRUST CO | $5.6M | 211,257 | 0.00% | 2q | +27.8%+$1.2M |
| AMERIPRISE FINANCIAL INC | $5.0M | 190,996 | 0.00% | 8q | +616.7%+$4.3M |
| Saturn V Capital Management LP | $4.8M | 182,829 | 0.69% | 2q | +105.4%+$2.5M |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $4.8M | 181,101 | 0.00% | new | NEW |
| TWO SIGMA INVESTMENTS, LP | $3.9M | 147,299 | 0.00% | 8q | -31.8%-$1.8M |
| Eversept Partners, LP | $3.4M | 128,286 | 0.18% | 2q | +2.5%+$82.3K |
| BOOTHBAY FUND MANAGEMENT, LLC | $2.8M | 106,234 | 0.04% | 8q | -23.7%-$872.7K |
| ALKEON CAPITAL MANAGEMENT LLC | $2.7M | 102,101 | 0.00% | 9q | -55.0%-$3.3M |
| STIFEL FINANCIAL CORP | $2.3M | 85,480 | 0.00% | 7q | -1.0%-$22.6K |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $2.1M | 80,583 | 0.00% | 3q | +373.5%+$1.7M |
| Sixth Street Partners Management Company, L.P. | $2.1M | 80,583 | 0.00% | new | NEW |
| AWM Investment Company, Inc. | $2.1M | 80,000 | 0.18% | 10q | -52.9%-$2.4M |
| Bank of New York Mellon Corp | $2.0M | 76,330 | 0.00% | new | NEW |
| MORGAN STANLEY | $2.0M | 74,940 | 0.00% | 10q | +9.2%+$165.9K |
| RENAISSANCE TECHNOLOGIES LLC | $1.9M | 71,399 | 0.00% | 5q | -31.0%-$847.1K |
| WELLINGTON MANAGEMENT GROUP LLP | $1.9M | 70,913 | 0.00% | 3q | +18.6%+$293.3K |
| AdvisorShares Investments LLC | $1.9M | 70,748 | 0.23% | 3q | +72.5%+$784.4K |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $1.8M | 7,998 | 0.00% | 8q | -96.6%-$52.7M |
| Nuveen, LLC | $1.6M | 62,342 | 0.00% | new | NEW |
| UBS Group AG | $1.5M | 58,697 | 0.00% | 10q | +240.3%+$1.1M |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | $1.3M | 50,653 | 0.02% | 6q | -3.8%-$52.8K |
| XTX Topco Ltd | $1.2M | 46,601 | 0.02% | 4q | +17.0%+$178.4K |
| TD Asset Management Inc | $1.2M | 43,800 | 0.00% | 2q | HELD |
| DIMENSIONAL FUND ADVISORS LP | $1.1M | 42,561 | 0.00% | 3q | +8.2%+$85.4K |
| Quantinno Capital Management LP | $1.0M | 38,556 | 0.00% | 5q | +6.9%+$65.6K |
| ALPS ADVISORS INC | $939.8K | 35,613 | 0.00% | 3q | +40.8%+$272.5K |
| RHUMBLINE ADVISERS | $834.9K | 31,636 | 0.00% | new | NEW |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | $797.8K | 30,233 | 0.00% | 2q | +27.3%+$171.2K |
| AMERICAN CENTURY COMPANIES INC | $707.8K | 26,820 | 0.00% | 3q | +89.1%+$333.4K |
| WELLS FARGO & COMPANY/MN | $694.1K | 26,303 | 0.00% | 3q | +1564.7%+$652.4K |
| DEUTSCHE BANK AG\ | $687.5K | 26,051 | 0.00% | new | NEW |
| BROWN ADVISORY INC | $659.8K | 25,000 | 0.00% | 7q | HELD |
| Allianz Asset Management GmbH | $640.7K | 28,500 | 0.00% | 8q | HELD |
| JANE STREET GROUP, LLC | $622.8K | options only | 0.00% | 5q | OPTIONS |
| ALLIANCEBERNSTEIN L.P. | $613.7K | 27,300 | 0.00% | new | NEW |
| UNIVERSITY OF TEXAS/TEXAS AM INVESTMENT MANAGEMENT CO | $585.2K | 22,175 | 0.07% | 10q | HELD |
| Squarepoint Ops LLC | $561.7K | 21,286 | 0.00% | 2q | -29.0%-$228.9K |
| CITIGROUP INC | $547.5K | 20,745 | 0.00% | 3q | +120.0%+$298.6K |
| BANK OF AMERICA CORP /DE/ | $504.1K | 19,101 | 0.00% | 10q | -25.6%-$173.5K |
| Revisor Wealth Management LLC | $452.1K | 17,130 | 0.11% | 2q | HELD |
| SCS Capital Management LLC | $444.4K | 16,840 | 0.00% | 6q | HELD |
| MetLife Investment Management, LLC | $412.8K | 15,644 | 0.00% | new | NEW |
| Virtus Investment Advisers, LLC | $402.2K | 15,239 | 0.09% | new | NEW |
| CITADEL ADVISORS LLC | $398.5K | options only | 0.00% | 8q | OPTIONS |
| BANK OF NOVA SCOTIA | $380.0K | 14,400 | 0.00% | new | NEW |
| Invesco Ltd. | $376.2K | 14,255 | 0.00% | new | NEW |
| BARCLAYS PLC | $351.5K | 13,318 | 0.00% | 10q | -46.8%-$309.2K |
| Vanguard Personalized Indexing Management, LLC | $334.0K | 12,658 | 0.00% | 5q | -19.1%-$78.9K |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | $316.9K | 12,009 | 0.00% | new | NEW |
| JPMORGAN CHASE & CO | $306.1K | 10,904 | 0.00% | 3q | +23604.3%+$304.8K |
| BANK OF MONTREAL /CAN/ | $301.2K | 11,415 | 0.00% | 5q | +0.6%+$1.9K |
| Vanguard Global Advisers, LLC | $281.0K | 10,649 | 0.00% | 2q | HELD |
| NEW YORK STATE COMMON RETIREMENT FUND | $242.8K | 9,200 | 0.00% | new | NEW |
| GK Wealth Management LLC | $226.0K | 8,565 | 0.12% | new | NEW |
| IEQ CAPITAL, LLC | $210.8K | 7,988 | 0.00% | 8q | -66.3%-$415.4K |
| PROFUND ADVISORS LLC | $208.7K | 7,908 | 0.01% | new | NEW |
| Police & Firemen's Retirement System of New Jersey | $203.9K | 7,725 | 0.00% | new | NEW |
| Persistent Asset Partners Ltd | $203.2K | 7,698 | 0.06% | new | NEW |
| State of Wyoming | $202.8K | 7,684 | 0.02% | new | NEW |
| FMR LLC | $166.9K | 6,325 | 0.00% | 10q | HELD |
| SIMPLEX TRADING, LLC | $113.5K | options only | 0.00% | new | OPTIONS |
| BNP PARIBAS FINANCIAL MARKETS | $102.4K | 3,880 | 0.00% | 9q | +1135.7%+$94.1K |
| ROYAL BANK OF CANADA | $95.0K | 3,575 | 0.00% | 9q | +8619.5%+$93.9K |
| Legal & General Group Plc | $67.1K | 2,543 | 0.00% | new | NEW |
| WHITTIER TRUST CO OF NEVADA INC | $63.8K | 2,482 | 0.00% | 7q | HELD |
| Russell Investments Group, Ltd. | $63.3K | 2,400 | 0.00% | 5q | +684.3%+$55.3K |
| Ameritas Investment Partners, Inc. | $62.7K | 2,377 | 0.00% | new | NEW |
| Tower Research Capital LLC (TRC) | $52.7K | 1,996 | 0.00% | 8q | +2970.8%+$51.0K |
| GROUP ONE TRADING LLC | $42.2K | options only | 0.00% | new | OPTIONS |
| PNC Financial Services Group, Inc. | $31.7K | 1,200 | 0.00% | 6q | HELD |
| LOS ANGELES CAPITAL MANAGEMENT LLC | $26.5K | 1,006 | 0.00% | new | NEW |
| ROTHSCHILD INVESTMENT LLC | $18.1K | 685 | 0.00% | 8q | -59.3%-$26.4K |
| STRS OHIO | $15.8K | 600 | 0.00% | new | NEW |
Five percent filings
Anyone crossing 5% of a company must say so within days - far sooner than the next quarterly holdings report. A 13D declares an intent to influence the company; a 13G is the passive version. See all activist filings →
| Filed | Form | Filer | % of class |
|---|---|---|---|
| 2026-08-14 | 13G/A | Vestal Point Capital, LPwith 1 co-filers | 2.2% |
| 2026-08-14 | 13G/A | Sirenia Capital Management LPwith 1 co-filers | 6.2% |
| 2026-08-14 | 13G/A | Perceptive Advisors LLCwith 2 co-filers | 10.0% |
| 2026-07-27 | 13G | BlackRock, Inc. | 6.0% |
| 2026-07-20 | 13G | EcoR1 Capital, LLCwith 2 co-filers | 5.8% |
Quarter by quarter
Coverage begins with the quarter ending 2018-12-31. Earlier filings exist only as occasional late amendments, too sparse to describe a market, so they are not shown.
| Quarter | Holders | Value | Shares | New | Added | Trimmed | Options |
|---|---|---|---|---|---|---|---|
| Q2 2026 | 117 | $771.6M | 29,139,515 | 30 | 37 | 24 | 0.4% |
| Q1 2026 | 109 | $603.9M | 26,413,531 | 22 | 26 | 40 | 1.8% |
| Q4 2025 | 95 | $442.4M | 24,399,108 | 26 | 25 | 23 | 1.8% |
| Q3 2025 | 74 | $68.0M | 16,878,004 | 8 | 18 | 23 | 0.2% |
| Q2 2025 | 79 | $37.9M | 17,218,439 | 17 | 19 | 24 | 0.1% |
| Q1 2025 | 80 | $45.0M | 20,787,653 | 18 | 15 | 25 | 0.2% |
| Q4 2024 | 76 | $92.1M | 21,684,692 | 21 | 29 | 10 | 0.4% |
| Q3 2024 | 79 | $260.7M | 20,992,623 | 27 | 33 | 9 | 6.7% |
| Q2 2024 | 55 | $183.0M | 17,122,221 | 16 | 17 | 11 | 0.0% |
| Q1 2024 | 50 | $226.9M | 14,801,220 | 50 | 0 | 0 | 0.0% |