SIONNA THERAPEUTICS INC (SION)
Institutional ownership reported to the SEC as of Q2 2026, across 6 quarters.
149
Reporting holders
$2.1B
Reported value
106.0%
Of shares outstanding
0.5%
Held as options
+30
Holder change
Institutions report 47,918,240 shares against 45,212,399 outstanding. Shares only - option lines are excluded, which is why this can be compared with the company at all. The count comes from the cover page of the company's own most recent report, so it is dated when that was filed rather than at quarter end. Over 100% because an adviser and a sub-adviser can both report the same shares, and both are counted.
Options share is the part of reported value carried in derivative lines rather than shares. A high figure means institutions are expressing a view on this security without owning much of it.
Holders
| Filer | Value | Shares | Their book | Held | Change |
|---|---|---|---|---|---|
| RA CAPITAL MANAGEMENT, L.P. | $435.7M | 9,905,045 | 3.79% | 6q | HELD |
| TPG GP A, LLC | $285.7M | 6,494,962 | 5.71% | 6q | HELD |
| VIKING GLOBAL INVESTORS LP | $140.6M | 3,195,181 | 0.40% | 6q | HELD |
| Atlas Venture Life Science Advisors, LLC | $131.8M | 2,995,602 | 14.95% | 6q | HELD |
| ORBIMED ADVISORS LLC | $112.4M | 2,555,877 | 2.08% | 6q | -27.6%-$42.9M |
| ENAVATE SCIENCES GP, LLC | $109.0M | 2,478,030 | 31.56% | 6q | HELD |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | $70.4M | 1,600,000 | 0.10% | 2q | +966.7%+$63.8M |
| BlackRock, Inc. | $64.9M | 1,474,769 | 0.00% | 6q | +13.8%+$7.9M |
| JPMORGAN CHASE & CO | $64.1M | 1,490,508 | 0.00% | 6q | +1.7%+$1.1M |
| JENNISON ASSOCIATES LLC | $51.6M | 1,172,133 | 0.03% | 6q | -19.2%-$12.3M |
| CITADEL ADVISORS LLC | $50.9M | 1,147,636 | 0.01% | 6q | -1.7%-$855.0K |
| VANGUARD CAPITAL MANAGEMENT LLC | $49.8M | 1,132,001 | 0.00% | 2q | +10.0%+$4.5M |
| STATE STREET CORP | $44.9M | 1,021,534 | 0.00% | 6q | +35.1%+$11.7M |
| PERCEPTIVE ADVISORS LLC | $39.8M | 905,000 | 0.60% | 6q | +37.4%+$10.8M |
| DEERFIELD MANAGEMENT COMPANY, L.P. | $30.0M | 680,916 | 0.31% | 6q | -29.8%-$12.7M |
| Siren, L.L.C. | $26.9M | 610,515 | 0.54% | 6q | +103.5%+$13.7M |
| EVENTIDE ASSET MANAGEMENT, LLC | $20.9M | 474,981 | 0.28% | 3q | -26.4%-$7.5M |
| GEODE CAPITAL MANAGEMENT, LLC | $20.1M | 457,145 | 0.00% | 6q | +17.3%+$3.0M |
| BAKER BROS. ADVISORS LP | $17.6M | 400,000 | 0.09% | 6q | HELD |
| Casdin Capital, LLC | $17.6M | 400,000 | 0.88% | new | NEW |
| Kalehua Capital Management LLC | $17.3M | 394,144 | 5.53% | 3q | HELD |
| GOLDMAN SACHS GROUP INC | $17.1M | 388,810 | 0.00% | 6q | +47.7%+$5.5M |
| Driehaus Capital Management LLC | $17.0M | 385,447 | 0.10% | 6q | +403.0%+$13.6M |
| MILLENNIUM MANAGEMENT LLC | $14.3M | 276,733 | 0.01% | 6q | +96.8%+$7.0M |
| FRANKLIN RESOURCES INC | $12.8M | 290,113 | 0.00% | 6q | +65.3%+$5.0M |
| Aberdeen Group plc | $12.5M | 284,138 | 0.02% | 6q | -49.6%-$12.3M |
| FMR LLC | $12.2M | 278,292 | 0.00% | 4q | +241.9%+$8.7M |
| Candriam S.C.A. | $10.2M | 233,208 | 0.05% | 2q | -1.5%-$158.4K |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $9.8M | 222,949 | 0.00% | 2q | +56.9%+$3.6M |
| Longaeva Partners L.P. | $8.6M | 196,352 | 0.19% | 4q | +1446.9%+$8.1M |
| Artisan Partners Limited Partnership | $8.3M | 189,498 | 0.01% | new | NEW |
| Ensign Peak Advisors, Inc | $8.1M | 184,532 | 0.01% | 3q | -63.9%-$14.4M |
| Soleus Capital Management, L.P. | $7.8M | 177,687 | 0.27% | 6q | -39.5%-$5.1M |
| NORTHERN TRUST CORP | $6.8M | 154,476 | 0.00% | 6q | +32.3%+$1.7M |
| MORGAN STANLEY | $6.6M | 151,047 | 0.00% | 6q | +13.5%+$792.9K |
| Sofinnova Investments, Inc. | $6.4M | 144,432 | 0.33% | new | NEW |
| Qube Research & Technologies Ltd | $6.2M | 140,309 | 0.01% | 2q | +232.2%+$4.3M |
| Alyeska Investment Group, L.P. | $6.0M | 136,222 | 0.02% | 6q | HELD |
| GordonMD Global Investments LP | $6.0M | 136,000 | 2.89% | 2q | HELD |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $5.7M | 129,753 | 0.00% | 6q | +7.9%+$417.9K |
| Sixth Street Partners Management Company, L.P. | $5.7M | 129,753 | 0.00% | new | NEW |
| Sio Capital Management, LLC | $5.6M | 127,808 | 0.93% | 2q | -56.6%-$7.3M |
| VANGUARD FIDUCIARY TRUST CO | $5.3M | 121,442 | 0.00% | 2q | +8.3%+$407.7K |
| Artia Global Partners LP | $5.3M | 119,741 | 0.97% | 3q | HELD |
| UBS Group AG | $5.1M | 116,206 | 0.00% | 6q | -21.3%-$1.4M |
| First Turn Management, LLC | $4.9M | 110,493 | 0.52% | new | NEW |
| CITIGROUP INC | $4.8M | 110,163 | 0.00% | 5q | +510.1%+$4.1M |
| Ikarian Capital, LLC | $4.7M | options only | 0.51% | new | OPTIONS |
| D. E. Shaw & Co., Inc. | $4.5M | 101,644 | 0.00% | new | NEW |
| Rock Springs Capital Management LP | $4.4M | 99,429 | 0.21% | 6q | HELD |
| Walleye Capital LLC | $4.3M | 97,347 | 0.02% | 2q | +544.8%+$3.6M |
| Rhenman & Partners Asset Management AB | $4.3M | 97,100 | 0.40% | 2q | +11.0%+$422.3K |
| BANK OF AMERICA CORP /DE/ | $3.9M | 88,908 | 0.00% | 6q | +74.8%+$1.7M |
| AMERIPRISE FINANCIAL INC | $3.6M | 82,232 | 0.00% | 6q | -49.8%-$3.6M |
| Integral Health Asset Management, LLC | $3.3M | 75,000 | 0.13% | 2q | +50.0%+$1.1M |
| SUPERSTRING CAPITAL MANAGEMENT LP | $2.8M | 63,156 | 1.75% | 3q | -55.2%-$3.4M |
| STEMPOINT CAPITAL LP | $2.6M | 59,426 | 0.45% | 2q | -18.7%-$600.6K |
| DEUTSCHE BANK AG\ | $2.3M | 53,353 | 0.00% | 5q | +302.7%+$1.8M |
| SEVEN GRAND MANAGERS, LLC | $2.2M | 50,000 | 0.09% | 3q | HELD |
| Point72 Asset Management, L.P. | $2.2M | 49,328 | 0.00% | 2q | -63.9%-$3.8M |
| TD Asset Management Inc | $2.1M | 47,396 | 0.00% | 6q | -42.9%-$1.6M |
| ALPS ADVISORS INC | $2.0M | 45,525 | 0.01% | 3q | +24.3%+$391.4K |
| SILVERARC CAPITAL MANAGEMENT, LLC | $1.9M | 42,478 | 0.19% | 6q | +7.8%+$134.7K |
| Russell Investments Group, Ltd. | $1.9M | 42,258 | 0.00% | 4q | -12.7%-$271.0K |
| Bank of New York Mellon Corp | $1.8M | 41,586 | 0.00% | 5q | +23.1%+$343.5K |
| Nuveen, LLC | $1.8M | 41,259 | 0.00% | 5q | +73.8%+$770.9K |
| XTX Topco Ltd | $1.7M | 38,096 | 0.02% | 3q | +61.8%+$639.8K |
| WELLINGTON MANAGEMENT GROUP LLP | $1.6M | 37,365 | 0.00% | 4q | -18.9%-$383.3K |
| MUTUAL OF AMERICA CAPITAL MANAGEMENT LLC | $1.6M | 35,968 | 0.02% | new | NEW |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | $1.6M | 35,420 | 0.00% | 6q | -45.0%-$1.3M |
| BOOTHBAY FUND MANAGEMENT, LLC | $1.4M | options only | 0.02% | new | OPTIONS |
| BNP PARIBAS FINANCIAL MARKETS | $1.4M | 31,803 | 0.00% | 5q | -21.6%-$385.7K |
| Ishara Investments LP | $1.4M | 123,000 | 0.99% | 2q | +150.0%+$810.3K |
| Swiss National Bank | $1.2M | 27,000 | 0.00% | new | NEW |
| Quadrature Capital Ltd | $1.1M | 26,023 | 0.01% | new | NEW |
| Trexquant Investment LP | $1.0M | 23,810 | 0.01% | new | NEW |
| NEW YORK STATE COMMON RETIREMENT FUND | $1.0M | 23,586 | 0.00% | 5q | +345.0%+$804.4K |
| ALLIANCEBERNSTEIN L.P. | $1.0M | 25,450 | 0.00% | 3q | +55.1%+$362.4K |
| TUDOR INVESTMENT CORP ET AL | $993.1K | 22,575 | 0.00% | new | NEW |
| RHUMBLINE ADVISERS | $981.4K | 22,309 | 0.00% | 5q | +21.9%+$176.0K |
| Maven Securities LTD | $879.8K | 20,000 | 0.02% | 2q | -20.0%-$219.9K |
| LOS ANGELES CAPITAL MANAGEMENT LLC | $820.2K | 18,645 | 0.00% | 3q | +353.0%+$639.1K |
| Susquehanna Portfolio Strategies, LLC | $793.3K | 18,034 | 0.01% | new | NEW |
| Rafferty Asset Management, LLC | $792.0K | 18,004 | 0.00% | 3q | -18.7%-$181.8K |
| Shay Capital LLC | $791.8K | 18,000 | 0.05% | new | NEW |
| WELLS FARGO & COMPANY/MN | $740.0K | 16,821 | 0.00% | 5q | +42.7%+$221.4K |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $695.0K | options only | 0.00% | 2q | OPTIONS |
| Engineers Gate Manager LP | $686.4K | 15,603 | 0.01% | new | NEW |
| KENNEDY CAPITAL MANAGEMENT LLC | $555.2K | 12,621 | 0.01% | 3q | +2.7%+$14.8K |
| MARSHALL WACE, LLP | $554.2K | 12,599 | 0.00% | new | NEW |
| Invesco Ltd. | $546.3K | 12,418 | 0.00% | 3q | +15.1%+$71.7K |
| MetLife Investment Management, LLC | $482.7K | 10,972 | 0.00% | 5q | +28.1%+$105.9K |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | $467.3K | 10,622 | 0.00% | 2q | +9056.9%+$462.2K |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | $463.4K | 10,582 | 0.00% | 5q | +15.2%+$61.2K |
| Jump Financial, LLC | $460.7K | 10,473 | 0.00% | new | NEW |
| Verition Fund Management LLC | $439.9K | options only | 0.00% | new | OPTIONS |
| VANGUARD ASSET MANAGEMENT, Ltd | $419.4K | 9,535 | 0.00% | new | NEW |
| PROFUND ADVISORS LLC | $402.1K | 9,140 | 0.01% | 3q | -8.0%-$35.1K |
| Virtus Investment Advisers, LLC | $400.7K | 9,109 | 0.09% | 5q | +42.9%+$120.3K |
| Legal & General Group Plc | $397.8K | 9,044 | 0.00% | 5q | +531.6%+$334.9K |
Showing the largest 100 of 152 reported holders.
Quarter by quarter
Coverage begins with the quarter ending 2018-12-31. Earlier filings exist only as occasional late amendments, too sparse to describe a market, so they are not shown.
| Quarter | Holders | Value | Shares | New | Added | Trimmed | Options |
|---|---|---|---|---|---|---|---|
| Q2 2026 | 149 | $2.1B | 47,918,240 | 38 | 54 | 41 | 0.5% |
| Q1 2026 | 119 | $1.8B | 45,226,577 | 27 | 40 | 27 | 0.0% |
| Q4 2025 | 95 | $1.8B | 43,185,560 | 26 | 36 | 20 | 0.0% |
| Q3 2025 | 75 | $1.3B | 44,180,949 | 18 | 20 | 17 | 0.0% |
| Q2 2025 | 62 | $738.6M | 42,572,775 | 24 | 18 | 9 | 0.0% |
| Q1 2025 | 46 | $423.6M | 40,495,735 | 46 | 0 | 0 | 0.0% |