TANGO THERAPEUTICS INC (TNGX)
Institutional ownership reported to the SEC as of Q2 2026, across 20 quarters.
236
Reporting holders
$6.4B
Reported value
123.3%
Of shares outstanding
0.3%
Held as options
+46
Holder change
Institutions report 207,821,682 shares against 168,610,367 outstanding. Shares only - option lines are excluded, which is why this can be compared with the company at all. The count comes from the cover page of the company's own most recent report, so it is dated when that was filed rather than at quarter end. Over 100% because an adviser and a sub-adviser can both report the same shares, and both are counted.
Options share is the part of reported value carried in derivative lines rather than shares. A high figure means institutions are expressing a view on this security without owning much of it.
Holders
| Filer | Value | Shares | Their book | Held | Change |
|---|---|---|---|---|---|
| RTW INVESTMENTS, LP | $434.5M | 13,900,620 | 3.71% | 3q | +4.5%+$18.8M |
| BlackRock, Inc. | $388.8M | 12,438,444 | 0.01% | 8q | +42.2%+$115.4M |
| FMR LLC | $385.5M | 12,333,339 | 0.02% | 20q | +24.5%+$75.9M |
| FARALLON CAPITAL MANAGEMENT, L.L.C. | $383.8M | 12,277,000 | 1.77% | 7q | +35.0%+$99.4M |
| Boxer Capital Management, LLC | $340.0M | 10,876,219 | 25.61% | 7q | HELD |
| GOLDMAN SACHS GROUP INC | $312.0M | 9,980,620 | 0.03% | 19q | +96.6%+$153.3M |
| TCG Crossover Management, LLC | $283.9M | 9,081,201 | 6.82% | 7q | -13.8%-$45.3M |
| Paradigm Biocapital Advisors LP | $198.7M | 6,357,523 | 3.72% | 2q | +58.6%+$73.4M |
| Siren, L.L.C. | $193.2M | 6,179,364 | 3.91% | 8q | +9.2%+$16.3M |
| STATE STREET CORP | $186.9M | 5,979,806 | 0.01% | 20q | +28.5%+$41.5M |
| VANGUARD CAPITAL MANAGEMENT LLC | $186.2M | 5,957,348 | 0.00% | 2q | +15.4%+$24.9M |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | $175.1M | 5,600,000 | 0.25% | 5q | -56.3%-$225.4M |
| Jupiter Topco LLC | $158.0M | 5,056,352 | 0.06% | new | FIRST |
| Deep Track Capital, LP | $131.3M | 4,200,000 | 1.91% | 4q | +52.7%+$45.3M |
| DEERFIELD MANAGEMENT COMPANY, L.P. | $131.0M | 4,190,611 | 1.37% | 3q | +1.1%+$1.4M |
| Woodline Partners LP | $125.1M | 4,000,567 | 0.39% | 7q | -50.0%-$125.0M |
| TRV GP IV, LLC | $120.2M | 6,374,574 | 47.37% | 20q | HELD |
| GEODE CAPITAL MANAGEMENT, LLC | $117.0M | 3,742,791 | 0.01% | 20q | +39.9%+$33.4M |
| PERCEPTIVE ADVISORS LLC | $105.6M | 3,377,000 | 1.58% | 3q | +317.9%+$80.3M |
| Seven Fleet Capital Management LP | $95.7M | 3,228,144 | 15.79% | 3q | +543.0%+$80.8M |
| Logos Global Management LP | $89.1M | 2,850,000 | 3.84% | 4q | -5.0%-$4.7M |
| Caligan Partners LP | $78.2M | 2,500,103 | 3.68% | 3q | +3.8%+$2.9M |
| Holocene Advisors, LP | $75.4M | 2,410,939 | 0.17% | 2q | -38.7%-$47.6M |
| Commodore Capital LP | $70.3M | 2,250,000 | 4.19% | new | NEW |
| Balyasny Asset Management L.P. | $66.2M | 2,016,379 | 0.08% | 9q | -47.3%-$59.4M |
| Jefferies Financial Group Inc. | $62.8M | 2,010,534 | 0.41% | new | NEW |
| FRANKLIN RESOURCES INC | $59.0M | 1,887,211 | 0.01% | 11q | +45.6%+$18.5M |
| Candriam S.C.A. | $50.9M | 1,630,553 | 0.23% | 5q | +28.5%+$11.3M |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $49.6M | 1,585,111 | 0.00% | 2q | +75.8%+$21.4M |
| JPMORGAN CHASE & CO | $46.3M | 1,418,193 | 0.00% | 20q | +2006.5%+$44.1M |
| Polar Capital Holdings Plc | $46.3M | 1,480,740 | 0.11% | new | NEW |
| Vivo Capital, LLC | $43.1M | 1,379,769 | 3.94% | 5q | -36.0%-$24.2M |
| DV EQUITIES, LLC | $41.2M | 1,318,551 | 5.91% | new | NEW |
| Cormorant Asset Management, LP | $40.6M | 1,300,000 | 2.08% | 2q | -8.8%-$3.9M |
| NORTHERN TRUST CORP | $38.5M | 1,231,933 | 0.00% | 20q | +42.8%+$11.5M |
| STEMPOINT CAPITAL LP | $38.4M | 1,223,019 | 6.62% | 2q | +204.4%+$25.8M |
| FEDERATED HERMES, INC. | $38.0M | 1,214,613 | 0.05% | 6q | +343011.0%+$38.0M |
| VOYA INVESTMENT MANAGEMENT LLC | $34.5M | 1,103,030 | 0.03% | 17q | +528.6%+$29.0M |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $33.5M | 1,072,059 | 0.00% | 20q | +27.8%+$7.3M |
| Sixth Street Partners Management Company, L.P. | $33.5M | 1,072,059 | 0.00% | new | NEW |
| AMERICAN CENTURY COMPANIES INC | $31.7M | 1,013,794 | 0.01% | new | NEW |
| Nantahala Capital Management, LLC | $31.3M | 1,001,318 | 0.52% | 7q | -19.9%-$7.8M |
| Integral Health Asset Management, LLC | $31.3M | 1,000,000 | 1.23% | 3q | +122.2%+$17.2M |
| VANGUARD FIDUCIARY TRUST CO | $28.6M | 915,565 | 0.01% | 2q | +38.1%+$7.9M |
| Nuveen, LLC | $27.8M | 890,170 | 0.01% | 6q | +146.7%+$16.5M |
| SAMLYN CAPITAL, LLC | $24.0M | 766,473 | 0.39% | new | NEW |
| RENAISSANCE TECHNOLOGIES LLC | $23.4M | 748,300 | 0.03% | new | NEW |
| Soleus Capital Management, L.P. | $22.2M | 709,000 | 0.76% | 5q | +57.6%+$8.1M |
| ArrowMark Colorado Holdings LLC | $22.1M | 708,385 | 0.92% | 11q | HELD |
| Bellevue Group AG | $21.7M | 694,182 | 0.46% | 3q | -71.1%-$53.3M |
| Alyeska Investment Group, L.P. | $21.6M | 691,109 | 0.06% | 2q | +3918.5%+$21.1M |
| Assenagon Asset Management S.A. | $21.6M | 690,312 | 0.01% | new | NEW |
| Connor, Clark & Lunn Investment Management Ltd. | $19.9M | 636,070 | 0.04% | 3q | +79.1%+$8.8M |
| BANK OF AMERICA CORP /DE/ | $18.8M | 600,834 | 0.00% | 19q | +83.7%+$8.6M |
| JANE STREET GROUP, LLC | $18.5M | 514,265 | 0.00% | 3q | HELD |
| Pictet Asset Management Holding SA | $18.3M | 582,262 | 0.02% | new | NEW |
| Fisher Asset Management, LLC | $18.1M | 578,158 | 0.01% | 11q | +256.0%+$13.0M |
| MORGAN STANLEY | $16.0M | 510,778 | 0.00% | 20q | -65.4%-$30.2M |
| FIRST TRUST ADVISORS LP | $15.9M | 509,309 | 0.01% | new | NEW |
| BOOTHBAY FUND MANAGEMENT, LLC | $15.6M | 500,497 | 0.21% | 3q | -12.4%-$2.2M |
| MILLENNIUM MANAGEMENT LLC | $15.5M | 496,036 | 0.01% | 7q | +16.5%+$2.2M |
| DIMENSIONAL FUND ADVISORS LP | $15.3M | 488,300 | 0.00% | 12q | HELD |
| Invesco Ltd. | $14.5M | 462,721 | 0.00% | 17q | -20.3%-$3.7M |
| Rock Springs Capital Management LP | $14.3M | 456,551 | 0.70% | 3q | +18.0%+$2.2M |
| BOONE CAPITAL MANAGEMENT LLC | $14.2M | 455,605 | 3.33% | new | NEW |
| Longaeva Partners L.P. | $13.0M | 414,902 | 0.28% | new | NEW |
| EVENTIDE ASSET MANAGEMENT, LLC | $12.5M | 400,000 | 0.17% | new | NEW |
| ACUTA CAPITAL PARTNERS, LLC | $12.2M | 390,949 | 8.52% | 3q | -11.5%-$1.6M |
| Bank of New York Mellon Corp | $12.2M | 390,920 | 0.00% | 20q | +22.8%+$2.3M |
| UBS Group AG | $12.0M | 383,694 | 0.00% | 10q | -45.1%-$9.9M |
| CONGRESS ASSET MANAGEMENT CO | $11.9M | 380,746 | 0.07% | 9q | +11.5%+$1.2M |
| Mass General Brigham, Inc | $11.1M | 354,192 | 3.07% | 6q | HELD |
| LMR Partners LLP | $10.9M | 347,106 | 0.04% | new | NEW |
| CITADEL ADVISORS LLC | $10.6M | 181,059 | 0.00% | 3q | +0.9%+$95.8K |
| BAKER BROS. ADVISORS LP | $10.4M | 333,333 | 0.05% | new | NEW |
| PFM Health Sciences, LP | $10.2M | 326,047 | 0.87% | 2q | -19.7%-$2.5M |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $10.1M | 105,985 | 0.00% | 14q | +22.7%+$1.9M |
| AMERIPRISE FINANCIAL INC | $9.6M | 306,345 | 0.00% | 2q | -69.7%-$22.1M |
| Point72 Asset Management, L.P. | $9.3M | 298,339 | 0.01% | 4q | -44.1%-$7.4M |
| WELLINGTON MANAGEMENT GROUP LLP | $9.3M | 297,106 | 0.00% | 4q | +2.7%+$247.8K |
| SCHRODER INVESTMENT MANAGEMENT GROUP | $9.1M | 278,511 | 0.01% | 2q | +34.2%+$2.3M |
| Russell Investments Group, Ltd. | $8.8M | 281,633 | 0.01% | 13q | +2093.4%+$8.4M |
| ALGERT GLOBAL LLC | $8.5M | 271,570 | 0.10% | 2q | -6.8%-$616.1K |
| HighVista Strategies LLC | $8.1M | 260,070 | 1.85% | 2q | +149.6%+$4.9M |
| SPHERA FUNDS MANAGEMENT LTD. | $7.9M | 254,250 | 1.04% | 3q | -26.0%-$2.8M |
| TWO SIGMA INVESTMENTS, LP | $7.6M | 241,783 | 0.01% | 14q | +39.7%+$2.1M |
| KVP Capital Advisors, LP | $7.2M | 230,264 | 5.28% | 2q | HELD |
| TD Asset Management Inc | $6.9M | 221,968 | 0.01% | 2q | +116.3%+$3.7M |
| Sio Capital Management, LLC | $6.5M | 208,500 | 1.08% | new | NEW |
| Atle Fund Management AB | $6.2M | 198,557 | 1.67% | 2q | +563.7%+$5.3M |
| TRV GP VI, LLC | $6.1M | 194,174 | 2.61% | 7q | HELD |
| Walleye Capital LLC | $6.0M | 192,270 | 0.02% | new | NEW |
| Swiss National Bank | $5.9M | 187,400 | 0.00% | 3q | +113.4%+$3.1M |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | $5.7M | 181,212 | 0.00% | 12q | +67.5%+$2.3M |
| VICTORY CAPITAL MANAGEMENT INC | $5.5M | 176,748 | 0.00% | 3q | +234.7%+$3.9M |
| RHUMBLINE ADVISERS | $5.5M | 175,133 | 0.00% | 17q | +38.3%+$1.5M |
| MARSHALL WACE, LLP | $5.5M | 174,909 | 0.00% | new | NEW |
| RAYMOND JAMES FINANCIAL INC | $5.3M | 170,301 | 0.00% | new | NEW |
| CITIGROUP INC | $4.8M | 152,007 | 0.00% | 20q | +674.2%+$4.1M |
| Ghisallo Capital Management LLC | $4.7M | 150,000 | 0.09% | new | NEW |
Five percent filings
Anyone crossing 5% of a company must say so within days - far sooner than the next quarterly holdings report. A 13D declares an intent to influence the company; a 13G is the passive version. See all activist filings →
| Filed | Form | Filer | % of class |
|---|---|---|---|
| 2026-08-14 | 13G | THE GOLDMAN SACHS GROUP, INC.with 1 co-filers | 6.0% |
| 2026-08-14 | 13G/A | Farallon Capital Management, L.L.C.with 28 co-filers | 9.8% |
| 2026-08-14 | 13G/A | Woodline Partners LP | 2.5% |
| 2026-08-14 | 13G/A | TCG Crossover GP II, LLCwith 2 co-filers | 7.0% |
| 2026-08-14 | 13G/A | Nextech Crossover I GP S.a. r.l.with 4 co-filers | 0.0% |
| 2026-08-12 | 13G/A | Adage Capital Management, L.P.with 2 co-filers | 3.4% |
Quarter by quarter
Coverage begins with the quarter ending 2018-12-31. Earlier filings exist only as occasional late amendments, too sparse to describe a market, so they are not shown.
| Quarter | Holders | Value | Shares | New | Added | Trimmed | Options |
|---|---|---|---|---|---|---|---|
| Q2 2026 | 236 | $6.4B | 207,821,682 | 69 | 96 | 54 | 0.3% |
| Q1 2026 | 190 | $3.7B | 179,060,360 | 53 | 61 | 52 | 0.1% |
| Q4 2025 | 161 | $1.5B | 170,941,711 | 47 | 73 | 25 | 0.1% |
| Q3 2025 | 134 | $1.1B | 135,622,754 | 39 | 39 | 33 | 0.1% |
| Q2 2025 | 107 | $632.9M | 123,342,166 | 23 | 37 | 27 | 0.2% |
| Q1 2025 | 110 | $139.7M | 101,990,983 | 15 | 38 | 32 | 0.0% |
| Q4 2024 | 123 | $313.6M | 101,655,400 | 32 | 33 | 27 | 0.0% |
| Q3 2024 | 108 | $736.0M | 95,579,409 | 13 | 35 | 32 | 0.0% |
| Q2 2024 | 110 | $798.8M | 93,091,971 | 18 | 33 | 32 | 0.0% |
| Q1 2024 | 114 | $743.3M | 93,620,035 | 23 | 33 | 31 | 0.0% |
| Q4 2023 | 106 | $916.4M | 92,561,967 | 26 | 36 | 18 | 0.0% |
| Q3 2023 | 87 | $981.5M | 87,168,081 | 18 | 29 | 22 | 0.0% |
| Q2 2023 | 78 | $197.9M | 59,638,476 | 10 | 19 | 25 | 0.0% |
| Q1 2023 | 75 | $256.2M | 64,901,220 | 17 | 18 | 19 | 0.0% |
| Q4 2022 | 64 | $440.0M | 60,737,752 | 9 | 21 | 16 | 0.0% |
| Q3 2022 | 86 | $246.8M | 68,167,033 | 20 | 21 | 16 | 0.0% |
| Q2 2022 | 76 | $319.1M | 70,452,128 | 26 | 26 | 10 | 0.0% |
| Q1 2022 | 71 | $528.2M | 69,680,149 | 20 | 20 | 11 | 0.0% |
| Q4 2021 | 57 | $742.3M | 67,892,079 | 18 | 12 | 7 | 0.0% |
| Q3 2021 | 45 | $844.9M | 65,465,348 | 45 | 0 | 0 | 0.0% |