CYTOMX THERAPEUTICS INC (CTMX)
Institutional ownership reported to the SEC as of Q2 2026, across 31 quarters.
178
Reporting holders
$809.7M
Reported value
98.1%
Of shares outstanding
1.0%
Held as options
+0
Holder change
Institutions report 213,809,925 shares against 217,899,284 outstanding. Shares only - option lines are excluded, which is why this can be compared with the company at all. The count comes from the cover page of the company's own most recent report, so it is dated when that was filed rather than at quarter end. A figure this high can overstate: where an adviser and a sub-adviser both report the same shares, both are counted.
Options share is the part of reported value carried in derivative lines rather than shares. A high figure means institutions are expressing a view on this security without owning much of it.
Holders
| Filer | Value | Shares | Their book | Held | Change |
|---|---|---|---|---|---|
| FMR LLC | $122.7M | 32,714,937 | 0.01% | 31q | +2.4%+$2.8M |
| Kynam Capital Management, LP | $81.4M | 21,703,093 | 4.50% | 5q | +44.6%+$25.1M |
| BlackRock, Inc. | $65.8M | 17,559,822 | 0.00% | 8q | +235.9%+$46.2M |
| BANK OF AMERICA CORP /DE/ | $56.6M | 15,082,617 | 0.00% | 31q | +47.8%+$18.3M |
| STATE STREET CORP | $44.1M | 11,747,236 | 0.00% | 31q | +107.4%+$22.8M |
| PERCEPTIVE ADVISORS LLC | $39.1M | 10,439,185 | 0.59% | 5q | +3.4%+$1.3M |
| VANGUARD CAPITAL MANAGEMENT LLC | $32.0M | 8,525,457 | 0.00% | 2q | -2.4%-$778.7K |
| Point72 Asset Management, L.P. | $29.3M | 7,811,033 | 0.03% | 7q | -0.8%-$241.3K |
| WELLINGTON MANAGEMENT GROUP LLP | $19.4M | 5,168,961 | 0.00% | 2q | +44.3%+$5.9M |
| Venrock Adviser, LLC | $18.7M | 4,982,124 | 0.57% | 5q | -50.1%-$18.8M |
| BAKER BROS. ADVISORS LP | $18.7M | 4,975,826 | 0.09% | 5q | HELD |
| GEODE CAPITAL MANAGEMENT, LLC | $17.5M | 4,678,716 | 0.00% | 31q | +126.4%+$9.8M |
| Elmind Capital, LP | $17.1M | 4,550,000 | 4.29% | 3q | HELD |
| Nextech Invest Ltd. | $16.7M | 4,449,932 | 0.79% | 2q | HELD |
| TWO SIGMA INVESTMENTS, LP | $15.5M | 4,132,643 | 0.01% | 31q | +52.5%+$5.3M |
| Eversept Partners, LP | $13.3M | 3,558,497 | 0.69% | 3q | +11.6%+$1.4M |
| UBS Group AG | $13.0M | 3,468,359 | 0.00% | 31q | +11.2%+$1.3M |
| Siren, L.L.C. | $13.0M | 3,457,711 | 0.26% | 2q | HELD |
| ADAR1 Capital Management, LLC | $12.6M | 3,365,118 | 0.58% | 10q | -1.3%-$169.0K |
| CITADEL ADVISORS LLC | $12.5M | 3,110,509 | 0.00% | 28q | -42.5%-$9.2M |
| MARSHALL WACE, LLP | $11.3M | 3,024,351 | 0.01% | 6q | -26.9%-$4.2M |
| Woodline Partners LP | $7.7M | 2,040,210 | 0.02% | 6q | +2.0%+$147.7K |
| GOLDMAN SACHS GROUP INC | $7.5M | 2,003,652 | 0.00% | 6q | +37.3%+$2.0M |
| DIMENSIONAL FUND ADVISORS LP | $7.0M | 1,860,290 | 0.00% | 5q | -3.7%-$264.9K |
| Qube Research & Technologies Ltd | $6.8M | 1,824,564 | 0.01% | 4q | -18.9%-$1.6M |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $6.6M | 1,751,167 | 0.00% | 2q | +120.3%+$3.6M |
| MILLENNIUM MANAGEMENT LLC | $6.3M | 1,685,830 | 0.00% | 31q | -53.9%-$7.4M |
| NORTHERN TRUST CORP | $6.3M | 1,675,183 | 0.00% | 31q | +173.7%+$4.0M |
| TUDOR INVESTMENT CORP ET AL | $5.4M | 1,380,687 | 0.01% | new | NEW |
| Caption Management, LLC | $5.3M | 300,000 | 0.02% | 2q | -47.7%-$4.8M |
| VANGUARD FIDUCIARY TRUST CO | $4.8M | 1,267,430 | 0.00% | 2q | +14.9%+$617.1K |
| Seven Fleet Capital Management LP | $4.1M | 1,085,398 | 0.67% | 3q | +192.2%+$2.7M |
| SPHERA FUNDS MANAGEMENT LTD. | $3.3M | 879,000 | 0.43% | 2q | +299.5%+$2.5M |
| Ally Bridge Group (NY) LLC | $2.9M | 775,000 | 2.57% | 2q | -13.9%-$468.8K |
| Assenagon Asset Management S.A. | $2.7M | 728,346 | 0.00% | 16q | +100.0%+$1.4M |
| DV EQUITIES, LLC | $2.7M | 714,000 | 0.38% | new | NEW |
| GILDER GAGNON HOWE & CO LLC | $2.6M | 704,423 | 0.03% | 2q | -37.1%-$1.6M |
| Bank of New York Mellon Corp | $2.6M | 684,539 | 0.00% | 31q | +136.2%+$1.5M |
| DEUTSCHE BANK AG\ | $2.5M | 663,038 | 0.00% | 2q | +43.1%+$748.6K |
| FIRST TRUST ADVISORS LP | $2.2M | 599,696 | 0.00% | 4q | +5.5%+$116.8K |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $2.1M | 549,875 | 0.00% | 16q | +326.9%+$1.6M |
| Sixth Street Partners Management Company, L.P. | $2.1M | 549,875 | 0.00% | new | NEW |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $2.0M | 90,673 | 0.00% | 29q | -95.2%-$40.1M |
| Ensign Peak Advisors, Inc | $1.9M | 505,055 | 0.00% | 2q | -57.4%-$2.5M |
| RAYMOND JAMES FINANCIAL INC | $1.8M | 484,222 | 0.00% | 5q | +27.4%+$390.2K |
| SCHULHOFF & CO INC | $1.8M | 477,550 | 0.72% | 3q | HELD |
| Exome Asset Management LLC | $1.7M | 460,067 | 1.06% | 4q | -11.8%-$230.3K |
| Nuveen, LLC | $1.7M | 448,041 | 0.00% | new | NEW |
| DAFNA Capital Management LLC | $1.6M | 438,407 | 0.31% | 2q | +90.6%+$781.5K |
| Stonepine Capital Management, LLC | $1.5M | 410,000 | 0.39% | 2q | +105.0%+$787.5K |
| Jump Financial, LLC | $1.3M | 347,400 | 0.01% | 2q | +3139.5%+$1.3M |
| Swiss National Bank | $1.2M | 325,400 | 0.00% | 2q | +1.8%+$21.8K |
| CITIGROUP INC | $1.1M | 287,866 | 0.00% | 4q | +182.8%+$697.7K |
| LMR Partners LLP | $1.0M | 273,213 | 0.00% | 2q | +16.3%+$143.6K |
| Tidal Investments LLC | $925.1K | 246,697 | 0.00% | 17q | HELD |
| Tema ETFs LLC | $858.7K | 228,987 | 0.03% | 2q | +0.7%+$5.6K |
| RHUMBLINE ADVISERS | $834.4K | 222,514 | 0.00% | new | NEW |
| Rafferty Asset Management, LLC | $830.2K | 221,377 | 0.00% | 3q | -7.7%-$69.2K |
| Invesco Ltd. | $825.8K | 220,205 | 0.00% | 5q | +257.7%+$594.9K |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | $824.2K | 219,779 | 0.00% | 2q | +16.0%+$113.9K |
| Focus Partners Wealth | $742.0K | 197,878 | 0.00% | new | NEW |
| MORGAN STANLEY | $715.5K | 190,799 | 0.00% | 35q | -63.3%-$1.2M |
| Verdad Advisers, LP | $661.5K | 176,407 | 0.63% | 2q | +484.4%+$548.3K |
| LPL Financial LLC | $644.0K | 171,733 | 0.00% | 17q | +40.0%+$184.1K |
| HighVista Strategies LLC | $636.9K | 169,831 | 0.15% | 4q | -41.0%-$443.3K |
| WELLS FARGO & COMPANY/MN | $611.9K | 163,183 | 0.00% | 4q | +1137.2%+$562.5K |
| AWM Investment Company, Inc. | $562.5K | 150,000 | 0.05% | 2q | HELD |
| CANADA PENSION PLAN INVESTMENT BOARD | $530.6K | 141,500 | 0.00% | 3q | +30.1%+$122.6K |
| GROUP ONE TRADING LLC | $498.4K | options only | 0.00% | 16q | OPTIONS |
| ALLIANCEBERNSTEIN L.P. | $490.3K | 104,310 | 0.00% | new | NEW |
| Walleye Capital LLC | $474.5K | 126,526 | 0.00% | new | NEW |
| BARCLAYS PLC | $474.1K | 126,415 | 0.00% | 6q | -11.2%-$60.0K |
| NLB Skladi, upravljanje premozenja, d.o.o. | $468.8K | 125,000 | 0.02% | 3q | +12.5%+$52.1K |
| Legal & General Group Plc | $462.4K | 123,313 | 0.00% | 2q | -13.1%-$69.7K |
| VANGUARD ASSET MANAGEMENT, Ltd | $460.8K | 122,893 | 0.00% | 2q | HELD |
| Velan Capital Investment Management LP | $450.0K | 120,000 | 0.27% | 7q | -77.8%-$1.6M |
| SIMPLEX TRADING, LLC | $422.2K | 10,286 | 0.00% | 8q | -95.9%-$9.8M |
| Squarepoint Ops LLC | $420.6K | 112,152 | 0.00% | 5q | -53.5%-$484.0K |
| PROFUND ADVISORS LLC | $417.7K | 111,378 | 0.01% | 3q | +6.5%+$25.7K |
| JPMORGAN CHASE & CO | $409.2K | 109,413 | 0.00% | 31q | +255.9%+$294.2K |
| Virtus Investment Advisers, LLC | $407.6K | 108,703 | 0.09% | 3q | +67.0%+$163.6K |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | $402.2K | 107,334 | 0.00% | 3q | +543.4%+$339.7K |
| ALPS ADVISORS INC | $401.6K | 107,100 | 0.00% | 2q | +1.2%+$4.8K |
| Merit Financial Group, LLC | $401.3K | 107,006 | 0.00% | 4q | +101.0%+$201.6K |
| MetLife Investment Management, LLC | $392.4K | 104,635 | 0.00% | new | NEW |
| Aspire Growth Partners LLC | $383.5K | 102,254 | 0.22% | 7q | HELD |
| Robertson Stephens Wealth Management, LLC | $360.0K | 96,000 | 0.01% | new | NEW |
| LANDSCAPE CAPITAL MANAGEMENT, L.L.C. | $353.4K | 94,240 | 0.02% | 2q | HELD |
| ALGERT GLOBAL LLC | $340.9K | 90,900 | 0.00% | new | NEW |
| Miller Financial Services LLC | $318.8K | 85,000 | 0.26% | 7q | +18.1%+$48.8K |
| Engineers Gate Manager LP | $311.7K | 83,130 | 0.00% | 3q | +182.0%+$201.2K |
| Zurcher Kantonalbank (Zurich Cantonalbank) | $299.3K | 79,816 | 0.00% | 2q | +66.3%+$119.4K |
| Vanguard Global Advisers, LLC | $268.6K | 71,617 | 0.00% | 2q | HELD |
| China Universal Asset Management Co., Ltd. | $242.4K | 64,647 | 0.01% | 3q | +17.4%+$35.9K |
| State of Wyoming | $206.2K | 54,987 | 0.02% | 3q | +4.4%+$8.6K |
| AMERICAN CENTURY COMPANIES INC | $205.9K | 54,899 | 0.00% | new | NEW |
| Private Advisor Group, LLC | $204.4K | 54,502 | 0.00% | 31q | +23.9%+$39.4K |
| Police & Firemen's Retirement System of New Jersey | $196.9K | 52,499 | 0.00% | new | NEW |
| State of New Jersey Common Pension Fund D | $196.6K | 52,424 | 0.00% | 2q | +64.6%+$77.2K |
| Universal- Beteiligungs- und Servicegesellschaft mbH | $189.5K | 50,529 | 0.00% | 2q | +89.5%+$89.5K |
Five percent filings
Anyone crossing 5% of a company must say so within days - far sooner than the next quarterly holdings report. A 13D declares an intent to influence the company; a 13G is the passive version. See all activist filings →
| Filed | Form | Filer | % of class |
|---|---|---|---|
| 2026-08-14 | 13G/A | Point72 Asset Management, L.P.with 2 co-filers | 3.6% |
| 2026-08-14 | 13G/A | Kynam Capital Management, LPwith 2 co-filers | 10.0% |
| 2026-08-07 | 13G | STATE STREET CORPORATION | 5.4% |
| 2026-08-03 | 13G | BANK OF AMERICA CORP /DE/ | 7.0% |
| 2026-07-27 | 13G | BlackRock, Inc. | 7.6% |
Quarter by quarter
Coverage begins with the quarter ending 2018-12-31. Earlier filings exist only as occasional late amendments, too sparse to describe a market, so they are not shown.
| Quarter | Holders | Value | Shares | New | Added | Trimmed | Options |
|---|---|---|---|---|---|---|---|
| Q2 2026 | 178 | $809.7M | 213,809,925 | 44 | 69 | 35 | 1.0% |
| Q1 2026 | 178 | $936.1M | 193,657,845 | 71 | 60 | 24 | 2.8% |
| Q4 2025 | 119 | $615.9M | 143,047,156 | 32 | 37 | 25 | 1.1% |
| Q3 2025 | 104 | $441.4M | 136,250,528 | 32 | 28 | 22 | 1.5% |
| Q2 2025 | 81 | $299.4M | 131,229,118 | 32 | 25 | 14 | 0.5% |
| Q1 2025 | 61 | $26.2M | 41,176,357 | 7 | 15 | 24 | 0.1% |
| Q4 2024 | 63 | $44.6M | 43,346,442 | 7 | 22 | 17 | 0.0% |
| Q3 2024 | 65 | $56.7M | 47,913,887 | 8 | 16 | 23 | 0.3% |
| Q2 2024 | 67 | $58.2M | 47,652,549 | 12 | 23 | 23 | 0.1% |
| Q1 2024 | 78 | $92.1M | 42,075,059 | 26 | 17 | 21 | 0.4% |
| Q4 2023 | 60 | $44.3M | 28,565,877 | 6 | 14 | 19 | 0.1% |
| Q3 2023 | 57 | $37.2M | 28,752,521 | 3 | 10 | 22 | 0.2% |
| Q2 2023 | 57 | $50.5M | 29,290,721 | 3 | 14 | 19 | 0.2% |
| Q1 2023 | 61 | $46.9M | 31,013,585 | 6 | 13 | 26 | 0.2% |
| Q4 2022 | 62 | $44.0M | 27,470,661 | 11 | 13 | 13 | 0.2% |
| Q3 2022 | 81 | $52.6M | 36,288,657 | 11 | 22 | 23 | 0.1% |
| Q2 2022 | 92 | $83.5M | 45,587,716 | 21 | 22 | 27 | 0.0% |
| Q1 2022 | 116 | $144.1M | 53,916,493 | 21 | 31 | 39 | 0.1% |
| Q4 2021 | 108 | $238.1M | 54,751,041 | 16 | 26 | 37 | 0.3% |
| Q3 2021 | 115 | $275.1M | 53,985,129 | 9 | 36 | 45 | 0.1% |
| Q2 2021 | 121 | $369.8M | 58,331,757 | 14 | 54 | 34 | 0.1% |
| Q1 2021 | 127 | $423.5M | 54,615,185 | 25 | 50 | 34 | 0.3% |
| Q4 2020 | 125 | $249.2M | 38,009,926 | 8 | 43 | 47 | 0.1% |
| Q3 2020 | 130 | $245.1M | 36,839,152 | 15 | 41 | 47 | 0.0% |
| Q2 2020 | 135 | $315.3M | 37,847,801 | 33 | 44 | 38 | 0.0% |
| Q1 2020 | 116 | $298.2M | 38,862,949 | 16 | 33 | 40 | 0.0% |
| Q4 2019 | 119 | $304.6M | 36,658,312 | 21 | 40 | 33 | 0.0% |
| Q3 2019 | 114 | $265.0M | 35,897,965 | 22 | 37 | 32 | 0.0% |
| Q2 2019 | 109 | $401.2M | 35,792,521 | 20 | 43 | 29 | 0.0% |
| Q1 2019 | 113 | $399.3M | 37,077,308 | 16 | 42 | 34 | 0.0% |
| Q4 2018 | 112 | $578.7M | 38,339,228 | 0 | 1 | 3 | 0.0% |