HolderBook

DAFNA Capital Management LLC

Reported holdings as of Q2 2026, from 31 quarterly filings.

CIK
1389933
Reported value
$524.4M
Positions
88
Top 10 weight
56.2%
Filed
2026-08-14
Days after quarter end
45

Holdings

SecurityTickerValue SharesWeightWeight change Held Change
REVOLUTION MEDICINES INCRVMD$105.4M562,63020.09%+7.25pp23q-3.1%-$3.4M
SPDR SERIES TRUSTXBI$31.1M196,5055.93%-3.32pp18q-38.3%-$19.3M
COMPASS PATHWAYS PLCCMPS$28.5M2,011,9525.43%+2.39pp12q-16.8%-$5.8M
STEREOTAXIS INCSTXS$23.5M13,680,5544.49%-1.24pp31qHELD
NEKTAR THERAPEUTICSNKTR$22.2M318,3804.24%+1.54pp5q+92.7%+$10.7M
DENALI THERAPEUTICS INCDNLI$19.0M739,0143.62%+2.23pp6q+132.0%+$10.8M
IDEAYA BIOSCIENCES INCIDYA$18.5M497,2403.53%-0.08pp24q+4.3%+$764.0K
ATRICURE INCATRC$16.7M597,4313.19%-0.69pp31qHELD
XENON PHARMACEUTICALS INCXENE$15.1M250,7722.89%-0.43pp31qHELD
CYTOKINETICS INCCYTK$14.7M171,9982.79%-0.47pp20q-20.9%-$3.9M
ARCUS BIOSCIENCES INCRCUS$13.6M441,8292.60%+0.42pp26qHELD
ASCENDIS PHARMA A/SASND$12.9M48,4692.47%-newNEW
NEUROCRINE BIOSCIENCES INCNBIX$9.7M57,7691.86%-0.26pp31q-18.2%-$2.2M
AXOGEN INCAXGN$9.7M208,9601.84%-0.04pp19q-16.4%-$1.9M
INSULET CORPPODD$9.4M61,8701.80%+1.28pp10q+469.2%+$7.8M
EDGEWISE THERAPEUTICS INCEWTX$9.2M226,8191.76%+0.95pp18q+102.1%+$4.7M
BICARA THERAPEUTICS INCBCAX$8.5M284,9551.61%-0.29pp7q-32.4%-$4.1M
ISHARES TRIBB$8.1M42,5951.54%-0.84pp31q-31.4%-$3.7M
SYNDAX PHARMACEUTICALS INCSNDX$7.3M335,2551.40%+0.24pp25q+54.2%+$2.6M
MAPLIGHT THERAPEUTICS INCMPLT$6.1M171,0061.17%+0.38pp3qHELD
LARIMAR THERAPEUTICS INCLRMR$6.1M2,008,1641.17%-0.91pp25q-1.0%-$64.0K
CENTURY THERAPEUTICS INCIPSC$5.9M2,400,4581.12%-0.13pp21q-1.4%-$83.0K
DEXCOM INCDXCM$5.8M86,2791.11%-0.12pp31qHELD
IMMUNOVANT INCIMVT$5.8M149,5241.10%+0.25pp12q-0.7%-$38.5K
INOGEN INCINGN$5.5M845,1791.04%-0.15pp30qHELD
TANDEM DIABETES CARE INCTNDM$5.4M355,2081.02%-0.53pp13qHELD
ALKERMES PLCALKS$5.3M101,2661.01%-0.11pp9q-27.4%-$2.0M
STOKE THERAPEUTICS INCSTOK$4.3M130,8750.82%-0.15pp10qHELD
ALLOGENE THERAPEUTICS INCALLO$4.2M2,000,0000.79%+0.03pp9q+46.0%+$1.3M
BIOCRYST PHARMACEUTICALS INCBCRX$4.0M400,2480.76%-0.17pp15q-7.0%-$300.0K
LAKEFRONT BIOTHERAPEUTICS NVLKFT$3.9M130,1750.74%-0.14pp31qHELD
ORTHOPEDIATRICS CORPKIDS$3.6M189,1300.69%+0.34pp2q+97.7%+$1.8M
CYBIN INCHELP$3.4M514,0610.65%+0.10pp3q+3.2%+$103.8K
RAPPORT THERAPEUTICS INCRAPP$3.1M75,0000.60%+0.06pp4qHELD
KYMERA THERAPEUTICS INCKYMR$3.1M27,0000.59%-newNEW
PROQR THRAPEUTICS N VPRQR$2.8M1,530,3610.54%-0.03pp14q-2.4%-$69.2K
NEUROGENE INCNGNE$2.8M89,0320.53%+0.27pp9q+57.2%+$1.0M
ADLAI NORTYE LTDANL$2.8M239,5530.53%-newNEW
PROCEPT BIOROBOTICS CORPPRCT$2.7M120,0000.52%-0.17pp3qHELD
AQUESTIVE THERAPEUTICS INCAQST$2.7M645,9150.51%+0.16pp10q+75.3%+$1.2M
CELLDEX THERAPEUTICS INC NEWCLDX$2.5M68,5180.49%-0.01pp4qHELD
STRUCTURE THERAPEUTICS INCGPCR$2.5M46,5000.48%-0.03pp9qHELD
ALIGN TECHNOLOGY INCALGN$2.4M14,0000.45%-0.13pp7q-6.7%-$168.7K
VIKING THERAPEUTICS INCVKTX$2.3M59,5160.44%flat31qHELD
NERVGEN PHARMA CORPNGEN$2.2M1,050,0000.41%-newNEW
BIOHAVEN LTDBHVN$2.0M137,5930.39%-1.24pp16q-83.7%-$10.5M
MAZE THERAPEUTICS INCMAZE$1.9M65,0000.37%+0.13pp2q+85.7%+$895.2K
ALECTOR INCALEC$1.8M908,3510.35%-0.10pp20qHELD
LEXEO THERAPEUTICS INCLXEO$1.8M377,0590.33%-0.16pp8qHELD
PROFOUND MED CORPPROF$1.7M260,3600.33%-0.06pp3q-1.0%-$17.6K
ATRIUM THERAPEUTICS INCRNA$1.7M128,0000.33%-newNEW
ANNEXON INCANNX$1.7M297,8120.32%+0.18pp3q+152.8%+$1.0M
CYTOMX THERAPEUTICS INCCTMX$1.6M438,4070.31%+0.07pp2q+90.6%+$781.5K
ULTRAGENYX PHARMACEUTICAL INRARE$1.6M47,1000.30%+0.01pp3q-22.9%-$467.5K
EUPRAXIA PHARMACEUTICALS INCEPRX$1.5M225,6000.28%-newNEW
DESIGN THERAPEUTICS INCDSGN$1.5M102,6000.28%-newNEW
FATE THERAPEUTICS INCFATE$1.4M525,0000.27%+0.12pp3q-4.5%-$67.5K
MEDIWOUND LTDMDWD$1.4M94,4050.26%-0.08pp15qHELD
KURA ONCOLOGY INCKURA$1.3M120,5680.25%-0.18pp31q-48.9%-$1.3M
ARS PHARMACEUTICALS INCSPRY$1.3M164,2850.25%flat4q+17.9%+$200.3K
MINERALYS THERAPEUTICS INCMLYS$1.2M44,4900.23%-0.01pp11q+15.6%+$161.9K
IMMATICS N.VIMTX$1.2M116,9600.23%-0.28pp11q-48.2%-$1.1M
TELA BIO INCTELA$1.1M1,441,0290.21%flat7qHELD
POLYPID LTDPYPD$1.1M207,9000.20%-0.01pp10qHELD
CORBUS PHARMACEUTICALS HLDGSCRBP$1.0M107,7730.19%-newNEW
INSPIRE MED SYS INCINSP$811.9K18,2000.15%-0.06pp4qHELD
ADICET BIO INCACET$810.5K93,8120.15%+0.01pp3qHELD
SEAPORT THERAPEUTICS INCSPTX$703.7K32,4000.13%-newNEW
MBX BIOSCIENCES INCMBX$651.9K11,8090.12%-1.07pp4q-93.3%-$9.0M
BIONTECH SEBNTX$651.4K7,0000.12%-0.02pp8qHELD
ARTIVA BIOTHERAPEUTICS INCARTV$650.9K67,1010.12%-newNEW
PLIANT THERAPEUTICS INCPLRX$555.2K487,0000.11%-0.03pp2qHELD
SCYNEXIS INC$553.0K135,8680.11%-newNEW
EDITAS MEDICINE INCEDIT$552.3K170,4700.11%-newNEW
ORCHESTRA BIOMED HLDGS INCOBIO$547.3K126,8410.10%-0.02pp4qHELD
FOGHORN THERAPEUTICS INCFHTX$545.9K111,8590.10%-0.02pp9qHELD
ACCURAY INC DELARAY$433.2K1,680,5080.08%-0.07pp29qHELD
Q32 BIO INCQTTB$419.1K32,8960.08%-newNEW
NUVECTIS PHARMA INCNVCT$367.8K20,0000.07%-newNEW
COMPUGEN LTDCGEN$360.0K168,2320.07%-0.06pp26q-34.7%-$191.6K
IBIO INCIBIO$297.6K170,0530.06%-0.03pp2q-12.2%-$41.3K
AUTOLUS THERAPEUTICS LTDAUTL$286.9K179,3160.05%flat18qHELD
BICYCLE THERAPEUTICS PLCBCYC$273.4K64,4920.05%-0.02pp18qHELD
TENAYA THERAPEUTICS INCTNYA$221.7K300,0000.04%-newNEW
VERRICA PHARMACEUTICALS INCVRCA$145.3K23,7500.03%-0.16pp3q-84.5%-$795.4K
Engene Therapeutics IncENGN$129.1K74,6500.02%-newNEW
KARDIGAN INCKARD$119.2K5,0000.02%-newNEW
ADC THERAPEUTICS SAADCT$82.5K77,0810.02%-0.05pp9q+6.9%+$5.4K

By sector

Industry comes from the SIC code on each company's own SEC filings, which is self-reported and sometimes out of date. Derivative exposure is counted with the shares. Securities the SEC assigns no industry - funds, trusts, foreign issues - are shown as not classified rather than dropped.

Biotech & Pharma 75.0%Medical Devices 17.2%Not classified 7.7%
 
SectorValueShare
Biotech & Pharma$393.5M75.0%
Medical Devices$90.3M17.2%
Not classified$40.6M7.7%

Quarter by quarter

QuarterValuePositions NewAddedTrimmed ExitedTop 10 Days to file
Q2 2026$524.4M881717251256.2%45
Q1 2026$439.6M83102029452.4%45
Q4 2025$430.5M771216291054.9%48
Q3 2025$404.8M757924857.1%45
Q2 2025$362.3M76321201055.8%45
Q1 2025$352.7M8382315752.8%45
Q4 2024$393.4M8262920852.5%45
Q3 2024$423.3M8461826548.9%45
Q2 2024$418.6M83141715347.8%45
Q1 2024$439.3M721012281449.5%45
Q4 2023$417.3M7671424649.6%45
Q3 2023$321.5M75102212850.5%45
Q2 2023$365.7M7381815749.4%45
Q1 2023$333.5M72423121152.0%45
Q4 2022$355.1M79516231350.3%45
Q3 2022$371.8M87910311247.8%45
Q2 2022$366.9M9043913847.4%46
Q1 2022$383.8M94113512446.5%46
Q4 2021$397.7M87132317651.4%45
Q3 2021$376.9M80720131150.7%46
Q2 2021$478.2M84725161253.5%47
Q1 2021$421.5M89222221750.2%47
Q4 2020$336.1M741016261656.9%47
Q3 2020$307.6M801119201853.0%47
Q2 2020$346.5M871710341048.5%45
Q1 2020$239.6M801029111150.2%45
Q4 2019$291.3M8178271554.0%45
Q3 2019$265.9M89102513848.5%45
Q2 2019$266.0M87172713946.6%45
Q1 2019$231.8M79721191146.1%45
Q4 2018$201.1M83000047.8%45

Rows marked UNVERIFIED ID, PLACEHOLDER ID, TICKER AS ID or NON-CUSIP ID carry an identifier that is not a valid CUSIP. They are shown because the filer reported that money, but treat the security named with caution - hover the chip for what is wrong with it, and see the methodology.

Held counts consecutive filings in which this manager reported the position, and can reach further back than the quarters listed above: the tabs begin at Q4 2018 because earlier coverage is too sparse to describe a market, but tenure is counted over every filing we hold, some reaching to 2007. A position sold and later rebought starts again from one.

Weight change is the shift in this position's share of the whole book, in percentage points. It is the more useful column: when money flows into or out of a broad fund, almost every holding is bought or sold at once, so added and trimmed largely track flows. A weight that rose while the book shrank is a decision. Both compare with the previous quarter this filer reported, not the previous calendar quarter.