ULTRAGENYX PHARMACEUTICAL IN (RARE)
Institutional ownership reported to the SEC as of Q2 2026, across 31 quarters.
300
Reporting holders
$3.6B
Reported value
107.0%
Of shares outstanding
3.6%
Held as options
+24
Holder change
Institutions report 105,460,949 shares against 98,588,873 outstanding. Shares only - option lines are excluded, which is why this can be compared with the company at all. The count comes from the cover page of the company's own most recent report, so it is dated when that was filed rather than at quarter end. Over 100% because an adviser and a sub-adviser can both report the same shares, and both are counted.
Options share is the part of reported value carried in derivative lines rather than shares. A high figure means institutions are expressing a view on this security without owning much of it.
Holders
| Filer | Value | Shares | Their book | Held | Change |
|---|---|---|---|---|---|
| BlackRock, Inc. | $355.7M | 10,654,276 | 0.01% | 8q | +46.0%+$112.0M |
| RTW INVESTMENTS, LP | $260.3M | 7,796,895 | 2.22% | 19q | +113.7%+$138.5M |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $226.7M | 6,790,135 | 0.01% | 2q | +26.1%+$46.9M |
| AQR CAPITAL MANAGEMENT LLC | $214.1M | 6,560,809 | 0.07% | 11q | +43.3%+$64.7M |
| STATE STREET CORP | $205.6M | 6,158,766 | 0.01% | 31q | +22.6%+$38.0M |
| VANGUARD CAPITAL MANAGEMENT LLC | $143.5M | 4,296,491 | 0.00% | 2q | +2.5%+$3.6M |
| TWO SIGMA INVESTMENTS, LP | $120.9M | 3,621,200 | 0.09% | 18q | +64.2%+$47.3M |
| SANDS CAPITAL MANAGEMENT, LLC | $105.5M | 3,158,368 | 0.39% | 13q | -1.7%-$1.9M |
| JACOBS LEVY EQUITY MANAGEMENT, INC | $98.2M | 2,939,719 | 0.35% | 5q | +105.4%+$50.4M |
| FRONTIER CAPITAL MANAGEMENT CO LLC | $95.1M | 2,847,936 | 0.89% | 5q | +30.0%+$21.9M |
| GEODE CAPITAL MANAGEMENT, LLC | $86.1M | 2,578,828 | 0.00% | 31q | +39.4%+$24.4M |
| Sofinnova Investments, Inc. | $74.0M | 1,717,505 | 3.83% | 3q | -45.4%-$61.6M |
| Bellevue Group AG | $66.2M | 1,982,775 | 1.39% | 3q | -16.7%-$13.3M |
| Palo Alto Investors LP | $59.8M | 1,789,485 | 2.75% | 5q | +200.0%+$39.8M |
| D. E. Shaw & Co., Inc. | $57.8M | 1,730,193 | 0.03% | 9q | +37.2%+$15.7M |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | $52.8M | 1,580,000 | 0.07% | 23q | +229.2%+$36.7M |
| MPM BIOIMPACT LLC | $47.4M | 1,418,215 | 2.89% | new | NEW |
| MORGAN STANLEY | $44.2M | 1,324,805 | 0.00% | 35q | -11.7%-$5.9M |
| Caption Management, LLC | $42.1M | 130,000 | 0.20% | 8q | +18.2%+$6.5M |
| WELLINGTON MANAGEMENT GROUP LLP | $41.8M | 1,250,464 | 0.01% | 31q | -52.6%-$46.4M |
| VOLORIDGE INVESTMENT MANAGEMENT, LLC | $41.5M | 1,241,556 | 0.18% | 4q | -13.0%-$6.2M |
| BANK OF AMERICA CORP /DE/ | $38.3M | 1,148,454 | 0.00% | 31q | +9.7%+$3.4M |
| Candriam S.C.A. | $33.4M | 1,001,841 | 0.15% | 23q | -8.6%-$3.1M |
| Rock Springs Capital Management LP | $32.3M | 967,855 | 1.58% | 31q | -20.6%-$8.4M |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $32.3M | 180,871 | 0.00% | 31q | -65.5%-$61.3M |
| Jefferies Financial Group Inc. | $31.0M | 929,626 | 0.20% | 3q | +5902.2%+$30.5M |
| NORTHERN TRUST CORP | $30.7M | 920,314 | 0.00% | 31q | +71.8%+$12.8M |
| Eagle Health Investments LP | $29.5M | 884,121 | 4.89% | 2q | HELD |
| Qube Research & Technologies Ltd | $29.5M | 882,219 | 0.03% | 2q | -3.6%-$1.1M |
| Russell Investments Group, Ltd. | $26.2M | 784,099 | 0.02% | 16q | +94.6%+$12.7M |
| MILLENNIUM MANAGEMENT LLC | $25.4M | 760,825 | 0.01% | 26q | -57.1%-$33.8M |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $25.4M | 760,039 | 0.00% | 31q | +36.1%+$6.7M |
| Sixth Street Partners Management Company, L.P. | $25.4M | 760,039 | 0.00% | new | NEW |
| Nuveen, LLC | $23.2M | 693,959 | 0.01% | 6q | +4.8%+$1.1M |
| Pictet Asset Management Holding SA | $23.2M | 753,695 | 0.02% | 12q | +24.9%+$4.6M |
| VANGUARD FIDUCIARY TRUST CO | $22.4M | 671,411 | 0.00% | 2q | +10.4%+$2.1M |
| UBS Group AG | $22.0M | 657,699 | 0.00% | 31q | -21.0%-$5.8M |
| GOLDMAN SACHS GROUP INC | $21.2M | 575,338 | 0.00% | 31q | +62.9%+$8.2M |
| GREAT POINT PARTNERS LLC | $20.0M | options only | 3.79% | new | OPTIONS |
| SPHERA FUNDS MANAGEMENT LTD. | $19.6M | 588,494 | 2.56% | 16q | -27.3%-$7.4M |
| Legal & General Group Plc | $19.6M | 586,520 | 0.00% | 31q | -0.6%-$126.0K |
| PANAGORA ASSET MANAGEMENT INC | $19.6M | 586,230 | 0.06% | new | NEW |
| FMR LLC | $19.3M | 576,849 | 0.00% | 31q | +100.8%+$9.7M |
| Trexquant Investment LP | $18.6M | 556,385 | 0.11% | 18q | +42.9%+$5.6M |
| BNP PARIBAS FINANCIAL MARKETS | $16.6M | 498,167 | 0.01% | 31q | +1.5%+$246.6K |
| Bank of New York Mellon Corp | $15.7M | 470,697 | 0.00% | 31q | +38.0%+$4.3M |
| JPMORGAN CHASE & CO | $15.3M | 493,126 | 0.00% | 31q | +100.5%+$7.7M |
| TORONTO DOMINION BANK | $13.9M | 415,000 | 0.02% | 3q | +256072.8%+$13.9M |
| RENAISSANCE TECHNOLOGIES LLC | $13.8M | 413,700 | 0.02% | 8q | -26.3%-$4.9M |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | $13.7M | 409,255 | 0.01% | 11q | -2.1%-$297.0K |
| ALGERT GLOBAL LLC | $13.0M | 389,964 | 0.15% | 14q | -54.5%-$15.6M |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | $12.7M | 381,420 | 0.01% | 18q | -15.5%-$2.3M |
| Stonepine Capital Management, LLC | $12.7M | 50,000 | 3.24% | new | NEW |
| SummitTX Capital, L.P. | $12.5M | 374,270 | 0.32% | 2q | +7.6%+$885.2K |
| CITADEL ADVISORS LLC | $11.6M | 210,531 | 0.00% | 31q | -90.0%-$105.0M |
| Walleye Capital LLC | $11.6M | 334,854 | 0.04% | 16q | +179.7%+$7.4M |
| Privium Fund Management B.V. | $11.3M | 338,800 | 2.08% | 19q | -7.1%-$868.2K |
| Squarepoint Ops LLC | $11.3M | 338,368 | 0.01% | 7q | -23.9%-$3.5M |
| Catalio Capital Management, LP | $10.6M | 316,252 | 1.98% | 5q | -62.8%-$17.8M |
| FRANKLIN RESOURCES INC | $10.5M | 315,766 | 0.00% | 28q | +1.0%+$104.8K |
| CITIGROUP INC | $10.0M | 298,785 | 0.00% | 31q | -5.3%-$556.1K |
| NOMURA ASSET MANAGEMENT INTERNATIONAL INC. | $9.9M | 297,819 | 0.01% | 3q | +63.8%+$3.9M |
| Ensign Peak Advisors, Inc | $9.7M | 290,818 | 0.02% | 19q | +2063.5%+$9.3M |
| GordonMD Global Investments LP | $9.7M | 289,101 | 4.67% | 3q | HELD |
| Jump Financial, LLC | $9.6M | 286,952 | 0.08% | 9q | -43.1%-$7.3M |
| Corient Private Wealth LP | $9.5M | 285,726 | 0.01% | 2q | +109.3%+$5.0M |
| MASSACHUSETTS FINANCIAL SERVICES CO /MA/ | $9.1M | 272,882 | 0.00% | 10q | +4.8%+$417.3K |
| Invesco Ltd. | $8.4M | 250,533 | 0.00% | 31q | -13.5%-$1.3M |
| Quantinno Capital Management LP | $8.4M | 250,466 | 0.01% | 4q | +33.6%+$2.1M |
| Assenagon Asset Management S.A. | $8.1M | 241,728 | 0.01% | 17q | -89.3%-$67.3M |
| KENNEDY CAPITAL MANAGEMENT LLC | $7.2M | 215,997 | 0.13% | 2q | -1.5%-$110.0K |
| WORLDQUANT MILLENNIUM ADVISORS LLC | $7.2M | 214,374 | 0.02% | 3q | +42.4%+$2.1M |
| SEI INVESTMENTS CO | $7.1M | 211,833 | 0.01% | 19q | +130.0%+$4.0M |
| Ishara Investments LP | $6.8M | 205,000 | 5.03% | 3q | +17.6%+$1.0M |
| Man Group plc | $6.5M | 195,110 | 0.01% | 18q | -8.6%-$609.1K |
| FIFTH THIRD BANCORP | $6.5M | 193,236 | 0.01% | 2q | +75.2%+$2.8M |
| Connor, Clark & Lunn Investment Management Ltd. | $6.4M | 191,578 | 0.01% | 17q | -61.8%-$10.3M |
| Blue Owl Capital Holdings LP | $6.1M | 182,638 | 0.92% | 11q | -39.7%-$4.0M |
| Woodline Partners LP | $5.7M | 171,805 | 0.02% | 13q | HELD |
| Atom Investors LP | $5.7M | 171,771 | 0.51% | 2q | +83.5%+$2.6M |
| Swiss National Bank | $5.6M | 167,652 | 0.00% | 31q | -2.0%-$113.5K |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | $5.6M | 167,226 | 0.00% | 31q | -25.0%-$1.9M |
| Ikarian Capital, LLC | $5.5M | 165,617 | 0.60% | 8q | -65.7%-$10.6M |
| DEUTSCHE BANK AG\ | $5.5M | 164,813 | 0.00% | 34q | +129.3%+$3.1M |
| MARSHALL WACE, LLP | $5.3M | 159,889 | 0.00% | 21q | +1.5%+$78.9K |
| SCHRODER INVESTMENT MANAGEMENT GROUP | $5.3M | 172,086 | 0.00% | 11q | -3.9%-$215.1K |
| WELLS FARGO & COMPANY/MN | $5.3M | 157,643 | 0.00% | 31q | +14.6%+$671.6K |
| BOOTHBAY FUND MANAGEMENT, LLC | $5.2M | 156,612 | 0.07% | 8q | +10.3%+$488.6K |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | $5.2M | 156,809 | 0.01% | 9q | +119.3%+$2.8M |
| BARCLAYS PLC | $5.2M | 154,876 | 0.00% | 31q | -38.0%-$3.2M |
| Eversept Partners, LP | $5.1M | 154,130 | 0.27% | 3q | +146.3%+$3.1M |
| Ghisallo Capital Management LLC | $5.0M | 150,000 | 0.10% | new | NEW |
| Mariner, LLC | $4.9M | 146,400 | 0.01% | 3q | +138.8%+$2.8M |
| FRED ALGER MANAGEMENT, LLC | $4.8M | 143,155 | 0.02% | 31q | -52.0%-$5.2M |
| MERCER GLOBAL ADVISORS INC /ADV | $4.7M | 142,113 | 0.00% | 4q | +320.6%+$3.6M |
| SR One Capital Management, LP | $4.6M | 137,753 | 0.44% | 3q | HELD |
| B Group, Inc. | $4.5M | 135,000 | 2.12% | 7q | HELD |
| PINNACLE ASSOCIATES LTD | $4.4M | 131,104 | 0.05% | 28q | +27.6%+$948.1K |
| MOORE CAPITAL MANAGEMENT, LP | $4.3M | 128,035 | 0.06% | 14q | -18.5%-$971.5K |
| RHUMBLINE ADVISERS | $4.1M | 124,125 | 0.00% | 31q | +20.0%+$691.8K |
Five percent filings
Anyone crossing 5% of a company must say so within days - far sooner than the next quarterly holdings report. A 13D declares an intent to influence the company; a 13G is the passive version. See all activist filings →
| Filed | Form | Filer | % of class |
|---|---|---|---|
| 2026-08-14 | 13G | RTW Investments, LPwith 1 co-filers | 7.9% |
| 2026-08-13 | 13G | AQR Capital Management, LLCwith 1 co-filers | 6.7% |
| 2026-08-07 | 13G | STATE STREET CORPORATION | 6.3% |
| 2026-07-31 | 13G | Vanguard Capital Management | 5.1% |
| 2026-07-31 | 13G/A | Vanguard Portfolio Management | 7.0% |
| 2026-07-30 | 13G/A | BlackRock, Inc. | 8.3% |
Quarter by quarter
Coverage begins with the quarter ending 2018-12-31. Earlier filings exist only as occasional late amendments, too sparse to describe a market, so they are not shown.
| Quarter | Holders | Value | Shares | New | Added | Trimmed | Options |
|---|---|---|---|---|---|---|---|
| Q2 2026 | 300 | $3.6B | 105,460,949 | 59 | 109 | 95 | 3.6% |
| Q1 2026 | 276 | $2.0B | 94,996,439 | 49 | 117 | 76 | 2.5% |
| Q4 2025 | 276 | $2.2B | 88,695,698 | 42 | 101 | 90 | 5.7% |
| Q3 2025 | 289 | $3.0B | 94,657,637 | 51 | 121 | 84 | 4.1% |
| Q2 2025 | 295 | $3.5B | 89,135,043 | 52 | 104 | 98 | 6.6% |
| Q1 2025 | 278 | $3.1B | 83,923,665 | 28 | 109 | 91 | 2.7% |
| Q4 2024 | 294 | $3.6B | 83,134,275 | 40 | 99 | 92 | 1.9% |
| Q3 2024 | 277 | $4.6B | 82,470,577 | 55 | 92 | 87 | 1.2% |
| Q2 2024 | 250 | $3.5B | 84,429,414 | 40 | 102 | 69 | 1.1% |
| Q1 2024 | 248 | $3.6B | 76,549,092 | 47 | 86 | 61 | 1.4% |
| Q4 2023 | 219 | $3.7B | 76,660,944 | 35 | 85 | 68 | 1.2% |
| Q3 2023 | 202 | $2.4B | 67,683,952 | 8 | 86 | 66 | 1.0% |
| Q2 2023 | 219 | $3.0B | 65,266,579 | 38 | 77 | 67 | 0.9% |
| Q1 2023 | 199 | $2.6B | 64,815,296 | 25 | 75 | 62 | 0.7% |
| Q4 2022 | 189 | $2.8B | 59,724,100 | 31 | 81 | 44 | 1.2% |
| Q3 2022 | 232 | $2.9B | 68,244,741 | 45 | 87 | 56 | 1.2% |
| Q2 2022 | 224 | $4.1B | 67,866,079 | 32 | 81 | 70 | 0.7% |
| Q1 2022 | 241 | $4.9B | 67,691,029 | 40 | 84 | 67 | 0.5% |
| Q4 2021 | 230 | $5.7B | 67,702,032 | 30 | 89 | 66 | 0.2% |
| Q3 2021 | 220 | $6.0B | 66,670,403 | 20 | 80 | 75 | 0.1% |
| Q2 2021 | 240 | $6.3B | 65,674,919 | 41 | 75 | 85 | 0.2% |
| Q1 2021 | 260 | $7.8B | 67,910,803 | 40 | 86 | 95 | 0.8% |
| Q4 2020 | 259 | $9.5B | 67,678,732 | 59 | 95 | 69 | 1.1% |
| Q3 2020 | 208 | $5.2B | 63,233,931 | 33 | 76 | 66 | 0.2% |
| Q2 2020 | 195 | $5.0B | 63,450,840 | 36 | 63 | 66 | 0.7% |
| Q1 2020 | 175 | $2.7B | 60,787,801 | 29 | 67 | 45 | 0.9% |
| Q4 2019 | 171 | $2.6B | 59,390,862 | 23 | 71 | 47 | 0.6% |
| Q3 2019 | 171 | $2.5B | 59,089,580 | 26 | 70 | 45 | 0.4% |
| Q2 2019 | 169 | $3.9B | 60,877,924 | 21 | 73 | 41 | 1.2% |
| Q1 2019 | 178 | $4.1B | 58,385,474 | 37 | 86 | 32 | 0.8% |
| Q4 2018 | 160 | $2.2B | 51,221,038 | 4 | 3 | 3 | 0.2% |