MAZE THERAPEUTICS INC (MAZE)
Institutional ownership reported to the SEC as of Q2 2026, across 6 quarters.
160
Reporting holders
$1.7B
Reported value
100.0%
Of shares outstanding
0.2%
Held as options
-6
Holder change
Institutions report 55,551,107 shares against 55,549,168 outstanding. Shares only - option lines are excluded, which is why this can be compared with the company at all. The count comes from the cover page of the company's own most recent report, so it is dated when that was filed rather than at quarter end. Over 100% because an adviser and a sub-adviser can both report the same shares, and both are counted.
Options share is the part of reported value carried in derivative lines rather than shares. A high figure means institutions are expressing a view on this security without owning much of it.
Holders
| Filer | Value | Shares | Their book | Held | Change |
|---|---|---|---|---|---|
| Frazier Life Sciences Management, L.P. | $150.2M | 5,032,915 | 3.27% | 6q | +10.2%+$13.9M |
| TRV GP IV, LLC | $133.5M | 4,473,958 | 52.63% | 6q | HELD |
| ARCH Venture Management, LLC | $123.0M | 4,120,053 | 11.18% | 6q | HELD |
| Deep Track Capital, LP | $111.4M | 3,732,569 | 1.62% | 6q | +7.3%+$7.6M |
| BlackRock, Inc. | $104.5M | 3,502,841 | 0.00% | 6q | +36.3%+$27.8M |
| Jupiter Topco LLC | $101.8M | 3,408,045 | 0.04% | new | FIRST |
| Logos Global Management LP | $57.7M | 1,935,000 | 2.49% | 6q | +56.7%+$20.9M |
| VANGUARD CAPITAL MANAGEMENT LLC | $53.1M | 1,778,222 | 0.00% | 2q | +23.9%+$10.2M |
| a16z Capital Management, L.L.C. | $50.8M | 1,702,225 | 0.36% | 6q | HELD |
| Venrock Adviser, LLC | $47.8M | 1,602,034 | 1.45% | 4q | HELD |
| Alphabet Inc. | $41.4M | 1,388,583 | 0.04% | 6q | HELD |
| BRAIDWELL LP | $34.0M | 1,140,040 | 1.26% | new | NEW |
| FARALLON CAPITAL MANAGEMENT, L.L.C. | $33.1M | 1,107,814 | 0.15% | 2q | +197.0%+$21.9M |
| FMR LLC | $31.5M | 1,056,959 | 0.00% | 6q | +22.3%+$5.8M |
| General Catalyst Group Management, LLC | $30.9M | 1,035,910 | 16.40% | 6q | HELD |
| STATE STREET CORP | $29.8M | 997,533 | 0.00% | 6q | +56.7%+$10.8M |
| Driehaus Capital Management LLC | $28.5M | 954,886 | 0.17% | 6q | +50.1%+$9.5M |
| TRV GP V, LLC | $28.4M | 950,800 | 5.69% | 6q | HELD |
| JPMORGAN CHASE & CO | $28.0M | 964,011 | 0.00% | 6q | +1549.4%+$26.3M |
| MARSHALL WACE, LLP | $27.3M | 914,572 | 0.02% | 6q | +194.4%+$18.0M |
| CITADEL ADVISORS LLC | $26.1M | 852,676 | 0.00% | 3q | +9.9%+$2.4M |
| GEODE CAPITAL MANAGEMENT, LLC | $25.6M | 858,054 | 0.00% | 6q | +43.0%+$7.7M |
| Casdin Capital, LLC | $25.2M | 843,857 | 1.26% | 6q | +11.2%+$2.5M |
| ArrowMark Colorado Holdings LLC | $22.9M | 767,383 | 0.95% | 4q | HELD |
| Woodline Partners LP | $22.0M | 736,216 | 0.07% | 6q | +13.2%+$2.6M |
| SPHERA FUNDS MANAGEMENT LTD. | $12.5M | 417,564 | 1.63% | 6q | +83.7%+$5.7M |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $11.7M | 393,107 | 0.00% | 2q | +101.0%+$5.9M |
| Aberdeen Group plc | $11.5M | 383,773 | 0.02% | 2q | +69.6%+$4.7M |
| Ikarian Capital, LLC | $11.3M | 378,999 | 1.22% | 6q | HELD |
| HHLR ADVISORS, LTD. | $10.9M | 366,028 | 1.31% | 6q | HELD |
| ADAR1 Capital Management, LLC | $10.1M | 339,276 | 0.46% | 4q | +577.3%+$8.6M |
| Squadron Capital Management LLC | $10.0M | 335,000 | 3.10% | 3q | +30.1%+$2.3M |
| BANK OF AMERICA CORP /DE/ | $9.6M | 321,227 | 0.00% | 6q | +64.7%+$3.8M |
| NORTHERN TRUST CORP | $8.8M | 294,742 | 0.00% | 6q | +39.4%+$2.5M |
| GOLDMAN SACHS GROUP INC | $8.7M | 293,144 | 0.00% | 3q | +4.8%+$400.8K |
| Candriam S.C.A. | $8.2M | 273,932 | 0.04% | 2q | -1.5%-$126.3K |
| Hudson Bay Capital Management LP | $8.1M | 270,000 | 0.02% | 2q | +3212.9%+$7.8M |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $7.8M | 260,566 | 0.00% | 6q | +39.8%+$2.2M |
| Sixth Street Partners Management Company, L.P. | $7.8M | 260,566 | 0.00% | new | NEW |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | $7.4M | 248,000 | 0.01% | 2q | -78.9%-$27.8M |
| Mass General Brigham, Inc | $7.2M | 239,994 | 1.98% | 3q | HELD |
| AMERIPRISE FINANCIAL INC | $6.8M | 227,425 | 0.00% | 3q | +5.8%+$371.6K |
| VANGUARD FIDUCIARY TRUST CO | $6.6M | 219,938 | 0.00% | 2q | +45.7%+$2.1M |
| RTW INVESTMENTS, LP | $6.3M | 212,000 | 0.05% | new | NEW |
| SCHRODER INVESTMENT MANAGEMENT GROUP | $5.8M | 199,872 | 0.00% | 2q | +437.6%+$4.7M |
| TWO SIGMA INVESTMENTS, LP | $5.8M | 192,952 | 0.00% | 4q | +1117.7%+$5.3M |
| BOOTHBAY FUND MANAGEMENT, LLC | $5.6M | 188,857 | 0.07% | 6q | -33.6%-$2.9M |
| ExodusPoint Capital Management, LP | $5.5M | 183,264 | 0.04% | new | NEW |
| SummitTX Capital, L.P. | $5.3M | 176,291 | 0.14% | 3q | +110.5%+$2.8M |
| HighVista Strategies LLC | $4.1M | 136,572 | 0.93% | 3q | +36.8%+$1.1M |
| MORGAN STANLEY | $4.0M | 135,168 | 0.00% | 6q | -34.0%-$2.1M |
| Qube Research & Technologies Ltd | $3.9M | 131,043 | 0.00% | 2q | -2.9%-$116.6K |
| Walleye Capital LLC | $3.8M | 128,006 | 0.01% | 2q | +358.1%+$3.0M |
| Exome Asset Management LLC | $3.4M | 114,692 | 2.11% | 2q | +29.6%+$781.3K |
| Ensign Peak Advisors, Inc | $3.0M | 101,644 | 0.00% | 5q | -72.6%-$8.1M |
| Alyeska Investment Group, L.P. | $3.0M | 100,000 | 0.01% | 6q | HELD |
| Bank of New York Mellon Corp | $2.9M | 97,588 | 0.00% | 6q | +31.4%+$695.9K |
| ALGERT GLOBAL LLC | $2.8M | 93,357 | 0.03% | new | NEW |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $2.6M | 23,677 | 0.00% | 6q | -6.4%-$180.5K |
| UBS Group AG | $2.5M | 84,679 | 0.00% | 6q | -9.8%-$275.1K |
| WELLINGTON MANAGEMENT GROUP LLP | $2.5M | 82,724 | 0.00% | 3q | +36.5%+$660.6K |
| Trexquant Investment LP | $2.4M | 81,668 | 0.01% | new | NEW |
| FRANKLIN RESOURCES INC | $2.4M | 80,216 | 0.00% | 4q | +34.5%+$614.1K |
| Nuveen, LLC | $2.3M | 78,468 | 0.00% | 6q | +23.8%+$450.8K |
| OSAIC HOLDINGS, INC. | $2.3M | 77,850 | 0.00% | 5q | +29.9%+$534.3K |
| BNP PARIBAS FINANCIAL MARKETS | $2.3M | 77,251 | 0.00% | 6q | +1093.1%+$2.1M |
| XTX Topco Ltd | $2.2M | 75,317 | 0.03% | 4q | +180.5%+$1.4M |
| LOS ANGELES CAPITAL MANAGEMENT LLC | $2.2M | 74,384 | 0.01% | 3q | +689.6%+$1.9M |
| RAYMOND JAMES FINANCIAL INC | $2.0M | 66,353 | 0.00% | 3q | -4.4%-$90.2K |
| JACOBS LEVY EQUITY MANAGEMENT, INC | $2.0M | 65,468 | 0.01% | new | NEW |
| DAFNA Capital Management LLC | $1.9M | 65,000 | 0.37% | 2q | +85.7%+$895.2K |
| ALPS ADVISORS INC | $1.7M | 55,970 | 0.01% | 2q | +42.9%+$501.3K |
| Jump Financial, LLC | $1.4M | 47,129 | 0.01% | new | NEW |
| Swiss National Bank | $1.4M | 47,100 | 0.00% | new | NEW |
| FIRST TRUST ADVISORS LP | $1.4M | 46,227 | 0.00% | 2q | +81.4%+$618.9K |
| Propel Bio Management, LLC | $1.3M | 43,798 | 0.68% | 2q | HELD |
| RHUMBLINE ADVISERS | $1.3M | 42,873 | 0.00% | 6q | +36.0%+$339.0K |
| NOMURA HOLDINGS INC | $1.3M | options only | 0.00% | 2q | OPTIONS |
| ALLIANCEBERNSTEIN L.P. | $1.1M | 37,800 | 0.00% | 6q | -41.6%-$804.8K |
| Verition Fund Management LLC | $1.1M | 36,402 | 0.00% | 3q | +90.2%+$515.3K |
| DEUTSCHE BANK AG\ | $1.0M | 34,993 | 0.00% | 6q | +72.7%+$439.5K |
| WELLS FARGO & COMPANY/MN | $956.3K | 32,047 | 0.00% | 6q | +54.5%+$337.5K |
| CITIGROUP INC | $903.1K | 30,265 | 0.00% | 6q | +253.4%+$647.6K |
| Quadrature Capital Ltd | $896.6K | 30,047 | 0.01% | new | NEW |
| Invesco Ltd. | $846.6K | 28,372 | 0.00% | 6q | -67.2%-$1.7M |
| AQR CAPITAL MANAGEMENT LLC | $810.5K | 27,161 | 0.00% | 5q | -2.8%-$23.4K |
| STATE OF WISCONSIN INVESTMENT BOARD | $711.4K | 23,840 | 0.00% | new | NEW |
| BARCLAYS PLC | $708.2K | 23,733 | 0.00% | 6q | +156.2%+$431.8K |
| TD Asset Management Inc | $661.7K | 22,174 | 0.00% | new | NEW |
| MetLife Investment Management, LLC | $623.6K | 20,899 | 0.00% | 4q | +43.7%+$189.7K |
| Balyasny Asset Management L.P. | $602.5K | 20,190 | 0.00% | 4q | -95.6%-$13.2M |
| Squarepoint Ops LLC | $579.9K | 19,434 | 0.00% | 2q | +42.8%+$173.7K |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | $529.3K | 17,739 | 0.00% | 3q | +4054.3%+$516.6K |
| VANGUARD ASSET MANAGEMENT, Ltd | $490.4K | 16,436 | 0.00% | new | NEW |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | $489.4K | 16,402 | 0.00% | 3q | +12.6%+$54.7K |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | $484.8K | 16,248 | 0.00% | 6q | +30.9%+$114.3K |
| Legal & General Group Plc | $470.9K | 15,781 | 0.00% | 6q | +172.6%+$298.1K |
| AXQ CAPITAL, LP | $453.4K | 15,193 | 0.05% | 2q | +114.1%+$241.6K |
| Russell Investments Group, Ltd. | $432.9K | 14,508 | 0.00% | 5q | -55.4%-$537.7K |
| Y-Intercept (Hong Kong) Ltd | $428.8K | 14,370 | 0.01% | 2q | -33.9%-$219.6K |
Five percent filings
Anyone crossing 5% of a company must say so within days - far sooner than the next quarterly holdings report. A 13D declares an intent to influence the company; a 13G is the passive version. See all activist filings →
| Filed | Form | Filer | % of class |
|---|---|---|---|
| 2026-08-14 | 13G/A | Paradigm BioCapital Advisors LPwith 3 co-filers | 0.0% |
| 2026-07-29 | 13G | BlackRock, Inc. | 5.4% |
Quarter by quarter
Coverage begins with the quarter ending 2018-12-31. Earlier filings exist only as occasional late amendments, too sparse to describe a market, so they are not shown.
| Quarter | Holders | Value | Shares | New | Added | Trimmed | Options |
|---|---|---|---|---|---|---|---|
| Q2 2026 | 160 | $1.7B | 55,551,107 | 41 | 64 | 36 | 0.2% |
| Q1 2026 | 166 | $1.5B | 51,379,145 | 49 | 56 | 36 | 1.0% |
| Q4 2025 | 140 | $2.0B | 47,943,605 | 52 | 42 | 20 | 0.1% |
| Q3 2025 | 90 | $1.1B | 42,549,473 | 22 | 38 | 13 | 0.1% |
| Q2 2025 | 72 | $470.8M | 38,353,169 | 12 | 24 | 12 | 0.0% |
| Q1 2025 | 66 | $436.1M | 39,556,579 | 65 | 0 | 0 | 0.0% |