HolderBook

ANNEXON INC (ANNX)

Institutional ownership reported to the SEC as of Q2 2026, across 24 quarters.

209
Reporting holders
$1.1B
Reported value
1.0%
Held as options
-2
Holder change

Options share is the part of reported value carried in derivative lines rather than shares. A high figure means institutions are expressing a view on this security without owning much of it.

Holders

FilerValueShares Their book Held Change
FMR LLC$111.5M19,518,4960.00%24q+83.5%+$50.7M
BlackRock, Inc.$77.3M13,539,7440.00%8q+23.8%+$14.9M
Redmile Group, LLC$67.8M11,869,8774.55%24q-18.4%-$15.3M
STATE STREET CORP$56.1M9,824,3210.00%24q+42.0%+$16.6M
Palo Alto Investors LP$50.5M8,844,2702.33%3q+200.0%+$33.7M
BVF INC/IL$49.7M8,698,1731.27%11qHELD
Woodline Partners LP$39.5M6,925,0670.12%17q+196.3%+$26.2M
VANGUARD CAPITAL MANAGEMENT LLC$39.2M6,871,0150.00%2q+15.4%+$5.2M
MAK CAPITAL ONE LLC$33.5M5,862,1804.69%3q+24.1%+$6.5M
GOLDMAN SACHS GROUP INC$33.3M5,825,5790.00%23q+170.6%+$21.0M
Siren, L.L.C.$25.5M4,458,6460.52%2q+12.6%+$2.9M
Bain Capital Life Sciences Investors, LLC$25.3M4,437,7311.51%24q-14.9%-$4.4M
Bellevue Group AG$23.4M4,100,0160.49%10q-20.5%-$6.0M
GEODE CAPITAL MANAGEMENT, LLC$23.1M4,037,1930.00%24q+19.5%+$3.8M
MPM BIOIMPACT LLC$20.2M3,544,3541.23%newNEW
AMERIPRISE FINANCIAL INC$20.0M3,509,6230.00%8q-49.1%-$19.3M
ADAGE CAPITAL PARTNERS GP, L.L.C.$20.0M3,500,0000.03%4q-18.6%-$4.6M
GREAT POINT PARTNERS LLC$20.0M3,500,0003.78%2q+40.0%+$5.7M
MORGAN STANLEY$18.0M3,144,4530.00%24q+14.9%+$2.3M
Balyasny Asset Management L.P.$16.2M2,830,9760.02%4q-27.2%-$6.0M
Nuveen, LLC$15.8M2,765,0800.00%6q-34.9%-$8.5M
Qube Research & Technologies Ltd$15.7M2,749,9610.01%10q-11.7%-$2.1M
VANGUARD PORTFOLIO MANAGEMENT LLC$12.8M2,246,8000.00%2q+51.5%+$4.4M
Opaleye Management Inc.$9.8M1,714,4510.89%4q-26.5%-$3.5M
Logos Global Management LP$8.6M1,500,0000.37%newNEW
DIMENSIONAL FUND ADVISORS LP$8.6M1,497,7560.00%19q+62.1%+$3.3M
Point72 Asset Management, L.P.$7.9M1,382,6990.01%4q-26.1%-$2.8M
NORTHERN TRUST CORP$7.7M1,352,0460.00%24q+24.4%+$1.5M
CHARLES SCHWAB INVESTMENT MANAGEMENT INC$7.2M1,257,7990.00%24q+14.1%+$887.1K
Sixth Street Partners Management Company, L.P.$7.2M1,257,7990.00%newNEW
Tetragon Partners GP Ltd$7.1M1,242,4551.12%9q-3.9%-$285.5K
Candriam S.C.A.$6.8M1,195,1420.03%newNEW
MILLENNIUM MANAGEMENT LLC$6.8M1,184,9310.00%20q-4.3%-$306.9K
VANGUARD FIDUCIARY TRUST CO$6.3M1,105,4500.00%2q+24.4%+$1.2M
MASSACHUSETTS FINANCIAL SERVICES CO /MA/$5.9M1,037,3660.00%24q+14.8%+$765.1K
JPMORGAN CHASE & CO$5.6M1,004,3080.00%24q+210.1%+$3.8M
WELLS FARGO & COMPANY/MN$5.6M978,0550.00%24q-30.0%-$2.4M
PANAGORA ASSET MANAGEMENT INC$5.5M967,9260.02%newNEW
CITADEL ADVISORS LLC$5.3M596,5820.00%24q-0.6%-$31.3K
KENNEDY CAPITAL MANAGEMENT LLC$5.1M898,3940.09%12q-1.5%-$79.5K
Ishara Investments LP$4.7M820,0003.44%3q+370.6%+$3.7M
Ensign Peak Advisors, Inc$4.6M800,5160.01%2q-36.0%-$2.6M
ARROWSTREET CAPITAL, LIMITED PARTNERSHIP$4.2M737,9350.00%newNEW
Y-Intercept (Hong Kong) Ltd$4.2M734,5850.08%2q-44.3%-$3.3M
Russell Investments Group, Ltd.$4.0M705,2910.00%4q-0.9%-$34.8K
AQR CAPITAL MANAGEMENT LLC$4.0M691,8120.00%10q-11.0%-$487.9K
SUSQUEHANNA INTERNATIONAL GROUP, LLP$3.7M39,3940.00%19q-75.2%-$11.1M
Parkman Healthcare Partners LLC$3.7M641,0290.37%10q-4.9%-$188.3K
UBS Group AG$3.6M623,0940.00%13q-50.0%-$3.6M
DEUTSCHE BANK AG\$3.5M616,4890.00%11q+9.7%+$310.1K
BANK OF AMERICA CORP /DE/$3.5M614,1860.00%24q-85.6%-$20.8M
DEERFIELD MANAGEMENT COMPANY, L.P.$3.3M583,9130.03%24qHELD
SIRIOS CAPITAL MANAGEMENT L P$3.3M569,2760.40%6q-1.0%-$33.0K
Schonfeld Strategic Advisors LLC$3.0M533,5670.01%18q+332.8%+$2.3M
TWO SIGMA INVESTMENTS, LP$2.9M512,7960.00%5q+8.8%+$236.4K
Hennion & Walsh Asset Management, Inc.$2.9M507,0500.08%9q-0.5%-$15.1K
Bank of New York Mellon Corp$2.9M501,4420.00%16q+26.9%+$607.7K
Board of Trustees of The Leland Stanford Junior University$2.8M482,5500.52%24qHELD
RENAISSANCE TECHNOLOGIES LLC$2.6M459,0000.00%19q-15.7%-$487.1K
Ikarian Capital, LLC$2.5M430,2440.26%3q-25.9%-$856.5K
MOORE CAPITAL MANAGEMENT, LP$2.4M425,3320.04%newNEW
Trexquant Investment LP$2.3M409,6670.01%2q+1.5%+$34.3K
WELLINGTON MANAGEMENT GROUP LLP$2.3M406,7950.00%3q-22.0%-$654.3K
Susquehanna Portfolio Strategies, LLC$2.3M395,2300.04%5q+9.7%+$199.3K
MUTUAL OF AMERICA CAPITAL MANAGEMENT LLC$2.3M394,6000.02%9q-5.3%-$126.2K
DIADEMA PARTNERS LP$2.2M27,5160.27%3q-79.3%-$8.3M
Invesco Ltd.$1.9M330,7290.00%13q-56.7%-$2.5M
SIMPLEX TRADING, LLC$1.8Moptions only0.00%10qOPTIONS
Engineers Gate Manager LP$1.8M319,0570.02%2q+83.2%+$827.5K
DAFNA Capital Management LLC$1.7M297,8120.32%3q+152.8%+$1.0M
Jump Financial, LLC$1.7M297,8000.01%newNEW
STATE OF WISCONSIN INVESTMENT BOARD$1.6M286,3750.00%2q+475.7%+$1.4M
D. E. Shaw & Co., Inc.$1.5M265,2840.00%3q-62.3%-$2.5M
VOLORIDGE INVESTMENT MANAGEMENT, LLC$1.4M250,0250.01%2q-45.9%-$1.2M
Swiss National Bank$1.4M244,6000.00%2q+3.6%+$49.1K
CITIGROUP INC$1.3M235,9900.00%24q+665.8%+$1.2M
Cinctive Capital Management LP$1.2M215,7480.05%10q-19.7%-$302.0K
MARSHALL WACE, LLP$1.2M210,6070.00%3q-75.6%-$3.7M
RHUMBLINE ADVISERS$1.1M189,5780.00%13q+18.7%+$170.8K
SEI INVESTMENTS CO$1.0M183,8170.00%3q-9.6%-$110.9K
UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC$1.0M180,6470.00%2q+38.3%+$285.5K
Squarepoint Ops LLC$989.5K173,2850.00%2q+155.0%+$601.4K
Rafferty Asset Management, LLC$989.4K173,2790.00%3q-14.8%-$171.2K
OSAIC HOLDINGS, INC.$842.9K147,6240.00%5q+11533.1%+$835.7K
ALLIANCEBERNSTEIN L.P.$815.7K147,2400.00%13q+23.7%+$156.2K
VICTORY CAPITAL MANAGEMENT INC$727.1K127,3380.00%9q+10.2%+$67.4K
BOOTHBAY FUND MANAGEMENT, LLC$685.9K120,1290.01%3q-27.7%-$262.9K
IEQ CAPITAL, LLC$685.3K120,0100.00%6q-38.7%-$432.6K
J. Goldman & Co LP$662.6K116,0460.02%4q-32.1%-$312.7K
XTX Topco Ltd$640.4K112,1470.01%4q+39.3%+$180.7K
Vanguard Global Advisers, LLC$582.8K102,0670.00%2q+88.8%+$274.2K
JANE STREET GROUP, LLC$573.9Koptions only0.00%11qOPTIONS
Quarry LP$571.0K100,0000.05%8q+370.6%+$449.7K
SCS Capital Management LLC$565.3K99,0000.01%2qHELD
Legal & General Group Plc$560.3K98,1180.00%13q+22.6%+$103.2K
GROUP ONE TRADING LLC$527.0K10,0870.00%10qHELD
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd.$520.6K91,6610.00%9q+20.2%+$87.5K
MetLife Investment Management, LLC$519.6K91,0050.00%10q+25.6%+$106.0K
J. Safra Sarasin Holding AG$516.7K90,4870.01%7qHELD
Zurcher Kantonalbank (Zurich Cantonalbank)$505.4K88,5180.00%2q+64.3%+$197.9K

Five percent filings

Anyone crossing 5% of a company must say so within days - far sooner than the next quarterly holdings report. A 13D declares an intent to influence the company; a 13G is the passive version. See all activist filings →

FiledFormFiler % of class
2026-08-0713GSTATE STREET CORPORATION6.0%
2026-07-2713G/ABlackRock, Inc.8.0%
2026-07-0813G/AFMR LLCwith 1 co-filers11.9%
2026-07-0813G/ARedmile Group, LLCwith 2 co-filers9.9%

Quarter by quarter

Coverage begins with the quarter ending 2018-12-31. Earlier filings exist only as occasional late amendments, too sparse to describe a market, so they are not shown.

QuarterHoldersValue SharesNewAdded TrimmedOptions
Q2 2026209$1.1B184,418,4782775801.0%
Q1 2026211$890.5M159,571,6965682450.8%
Q4 2025159$687.4M135,548,5453968271.0%
Q3 2025136$306.2M100,164,2173047340.2%
Q2 2025120$236.5M98,473,0171546310.1%
Q1 2025137$190.2M98,594,8822246330.1%
Q4 2024142$568.5M110,593,0032058330.3%
Q3 2024132$651.1M109,725,2561850360.4%
Q2 2024135$576.0M110,477,8094250316.1%
Q1 2024117$694.3M94,083,5523936222.8%
Q4 202390$358.8M79,201,9681433230.1%
Q3 202386$122.3M51,891,7011226240.3%
Q2 202388$185.3M52,387,4962832170.9%
Q1 202386$170.3M43,935,3912826110.9%
Q4 202269$205.9M38,875,2051318152.4%
Q3 202274$299.0M47,562,8251123202.2%
Q2 202277$148.2M38,411,0322210332.3%
Q1 202299$106.0M38,728,5012333240.1%
Q4 202194$448.2M38,812,0122432210.4%
Q3 202182$708.6M38,056,6511626250.0%
Q2 202174$873.7M38,854,7341333130.0%
Q1 202172$1.0B37,426,974736120.0%
Q4 202070$904.3M36,208,9351430130.0%
Q3 202065$1.0B34,842,57465000.0%