MINERALYS THERAPEUTICS INC (MLYS)
Institutional ownership reported to the SEC as of Q2 2026, across 14 quarters.
219
Reporting holders
$2.7B
Reported value
111.5%
Of shares outstanding
2.9%
Held as options
+11
Holder change
Institutions report 98,543,863 shares against 88,406,885 outstanding. Shares only - option lines are excluded, which is why this can be compared with the company at all. The count comes from the cover page of the company's own most recent report, so it is dated when that was filed rather than at quarter end. Over 100% because an adviser and a sub-adviser can both report the same shares, and both are counted.
Options share is the part of reported value carried in derivative lines rather than shares. A high figure means institutions are expressing a view on this security without owning much of it.
Holders
| Filer | Value | Shares | Their book | Held | Change |
|---|---|---|---|---|---|
| Catalys Pacific, LLC | $213.2M | 7,903,838 | 92.94% | 11q | HELD |
| RA CAPITAL MANAGEMENT, L.P. | $207.6M | 7,692,750 | 1.80% | 14q | HELD |
| BlackRock, Inc. | $158.8M | 5,887,038 | 0.00% | 8q | +31.4%+$37.9M |
| SAMSARA BIOCAPITAL, LLC | $158.4M | 5,871,018 | 13.01% | 14q | HELD |
| FMR LLC | $121.7M | 4,511,689 | 0.01% | 14q | -7.2%-$9.4M |
| STATE STREET CORP | $111.7M | 4,141,636 | 0.00% | 14q | +41.1%+$32.5M |
| DEERFIELD MANAGEMENT COMPANY, L.P. | $106.8M | 3,958,000 | 1.11% | new | NEW |
| ARMISTICE CAPITAL, LLC | $74.9M | 1,736,000 | 0.92% | 5q | +47.6%+$24.2M |
| VANGUARD CAPITAL MANAGEMENT LLC | $74.4M | 2,756,770 | 0.00% | 2q | +12.3%+$8.2M |
| Laurion Capital Management LP | $67.6M | 2,506,152 | 1.73% | 14q | +12.3%+$7.4M |
| ORBIMED ADVISORS LLC | $56.9M | 2,110,300 | 1.05% | 5q | +2.8%+$1.5M |
| Capital World Investors | $53.9M | 1,997,607 | 0.01% | 2q | +401.7%+$43.2M |
| Troluce Capital Advisors LLC | $48.0M | 1,728,753 | 4.94% | 2q | +163.9%+$29.8M |
| Nantahala Capital Management, LLC | $44.3M | 1,640,962 | 0.74% | 10q | +83.2%+$20.1M |
| FRANKLIN RESOURCES INC | $44.1M | 1,635,520 | 0.01% | 14q | -8.4%-$4.0M |
| ANDERA PARTNERS | $42.9M | 1,591,917 | 20.80% | 3q | HELD |
| GEODE CAPITAL MANAGEMENT, LLC | $42.8M | 1,584,326 | 0.00% | 14q | +21.8%+$7.6M |
| SR One Capital Management, LP | $42.2M | 1,563,966 | 4.06% | 14q | HELD |
| BANK OF AMERICA CORP /DE/ | $40.6M | 1,505,547 | 0.00% | 14q | +36.8%+$10.9M |
| GOLDMAN SACHS GROUP INC | $40.3M | 1,458,676 | 0.00% | 11q | +85.8%+$18.6M |
| SPHERA FUNDS MANAGEMENT LTD. | $39.7M | 1,469,971 | 5.17% | 14q | +9.7%+$3.5M |
| Pictet Asset Management Holding SA | $38.6M | 1,430,649 | 0.04% | 6q | +38.3%+$10.7M |
| Polar Capital Holdings Plc | $38.3M | 1,420,854 | 0.09% | 4q | -5.3%-$2.2M |
| Caption Management, LLC | $38.0M | 413,087 | 0.18% | 6q | HELD |
| MILLENNIUM MANAGEMENT LLC | $33.8M | 1,221,758 | 0.01% | 12q | +132.6%+$19.3M |
| Ghisallo Capital Management LLC | $30.4M | 1,125,000 | 0.60% | new | NEW |
| Invesco Ltd. | $29.4M | 1,091,180 | 0.00% | 6q | +2479.0%+$28.3M |
| ALLIANCEBERNSTEIN L.P. | $28.9M | 1,067,541 | 0.01% | 13q | +9.4%+$2.5M |
| Logos Global Management LP | $28.3M | 1,050,000 | 1.22% | new | NEW |
| AMERICAN CENTURY COMPANIES INC | $28.0M | 1,036,767 | 0.01% | 14q | +17.3%+$4.1M |
| MORGAN STANLEY | $24.7M | 917,213 | 0.00% | 14q | +8.0%+$1.8M |
| Davern Capital Partners, LP | $23.2M | 858,753 | 3.95% | 3q | +92.0%+$11.1M |
| Candriam S.C.A. | $23.1M | 857,037 | 0.10% | 7q | +6.9%+$1.5M |
| WELLINGTON MANAGEMENT GROUP LLP | $21.8M | 806,716 | 0.00% | 8q | -76.0%-$68.9M |
| Affinity Asset Advisors, LLC | $20.2M | 750,000 | 0.91% | 10q | HELD |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $20.2M | 747,657 | 0.00% | 2q | +5.8%+$1.1M |
| TUDOR INVESTMENT CORP ET AL | $20.1M | 738,370 | 0.03% | 3q | +374.1%+$15.9M |
| Aberdeen Group plc | $18.6M | 689,235 | 0.03% | new | NEW |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $18.0M | 355,570 | 0.00% | 7q | +2154.7%+$17.2M |
| ALGERT GLOBAL LLC | $17.5M | 649,027 | 0.21% | 4q | +24.7%+$3.5M |
| Catalio Capital Management, LP | $17.5M | 648,722 | 3.29% | 3q | +47.8%+$5.7M |
| Pale Fire Capital SE | $16.6M | 614,284 | 1.17% | 11q | +68.0%+$6.7M |
| STEMPOINT CAPITAL LP | $16.3M | 602,686 | 2.80% | 7q | -43.5%-$12.5M |
| CITADEL ADVISORS LLC | $16.1M | 467,598 | 0.00% | 6q | -22.1%-$4.6M |
| NORTHERN TRUST CORP | $14.9M | 551,491 | 0.00% | 14q | +24.5%+$2.9M |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $14.1M | 521,216 | 0.00% | 14q | +17.4%+$2.1M |
| Sixth Street Partners Management Company, L.P. | $14.1M | 521,216 | 0.00% | new | NEW |
| Rock Springs Capital Management LP | $13.1M | 484,951 | 0.64% | 6q | +10.3%+$1.2M |
| DIMENSIONAL FUND ADVISORS LP | $12.5M | 463,387 | 0.00% | 7q | +237.2%+$8.8M |
| VANGUARD FIDUCIARY TRUST CO | $12.2M | 450,370 | 0.00% | 2q | +20.0%+$2.0M |
| Integral Health Asset Management, LLC | $12.1M | 450,000 | 0.48% | 8q | -40.0%-$8.1M |
| Prosight Management, LP | $12.1M | 449,795 | 2.09% | new | NEW |
| Rhenman & Partners Asset Management AB | $11.2M | 416,371 | 1.06% | 4q | +58.3%+$4.1M |
| JENNISON ASSOCIATES LLC | $10.3M | 382,747 | 0.01% | 9q | -69.8%-$23.8M |
| Parkman Healthcare Partners LLC | $10.3M | 380,354 | 1.05% | 6q | HELD |
| RENAISSANCE TECHNOLOGIES LLC | $10.2M | 378,300 | 0.01% | 12q | -1.2%-$121.4K |
| CenterBook Partners LP | $9.9M | 365,630 | 0.48% | 3q | +309.3%+$7.5M |
| UBS Group AG | $9.8M | 361,596 | 0.00% | 13q | +268.9%+$7.1M |
| D. E. Shaw & Co., Inc. | $9.5M | 352,729 | 0.00% | 6q | -60.2%-$14.4M |
| Eversept Partners, LP | $8.4M | 309,689 | 0.43% | new | NEW |
| SCHRODER INVESTMENT MANAGEMENT GROUP | $8.3M | 307,214 | 0.01% | 3q | +135.2%+$4.7M |
| ADAR1 Capital Management, LLC | $8.1M | 298,886 | 0.37% | 10q | +93.2%+$3.9M |
| Longaeva Partners L.P. | $7.6M | 281,104 | 0.17% | new | NEW |
| Nuveen, LLC | $7.4M | 274,843 | 0.00% | 6q | +145.4%+$4.4M |
| Qube Research & Technologies Ltd | $6.7M | 249,776 | 0.01% | 5q | -72.7%-$17.9M |
| TimesSquare Capital Management, LLC | $6.4M | 235,858 | 0.09% | 3q | -30.4%-$2.8M |
| MONTANOVA CAPITAL, LLC | $4.7M | 173,886 | 0.09% | 6q | -88.7%-$36.8M |
| Trexquant Investment LP | $4.6M | 169,715 | 0.03% | 6q | +196.7%+$3.0M |
| TWO SIGMA INVESTMENTS, LP | $4.4M | 162,082 | 0.00% | 3q | -48.0%-$4.0M |
| Bank of New York Mellon Corp | $4.3M | 158,550 | 0.00% | 14q | +22.0%+$771.3K |
| Brevan Howard Capital Management LP | $4.1M | 153,722 | 0.03% | 3q | +69.1%+$1.7M |
| AQR CAPITAL MANAGEMENT LLC | $4.1M | 152,504 | 0.00% | 6q | +2.3%+$92.2K |
| GROUP ONE TRADING LLC | $4.1M | 25,471 | 0.01% | 6q | HELD |
| Burkehill Global Management, LP | $4.0M | 150,000 | 0.15% | 4q | HELD |
| BOOTHBAY FUND MANAGEMENT, LLC | $4.0M | 147,402 | 0.05% | 9q | -85.3%-$23.0M |
| Artia Global Partners LP | $3.7M | 137,800 | 0.69% | 5q | HELD |
| JANE STREET GROUP, LLC | $3.6M | options only | 0.00% | 4q | OPTIONS |
| Russell Investments Group, Ltd. | $3.5M | 128,247 | 0.00% | 5q | -37.0%-$2.0M |
| VOYA INVESTMENT MANAGEMENT LLC | $3.4M | 125,991 | 0.00% | 6q | -41.7%-$2.4M |
| SIMPLEX TRADING, LLC | $3.2M | 35,979 | 0.00% | 9q | +83.9%+$1.5M |
| Ensign Peak Advisors, Inc | $3.2M | 118,382 | 0.01% | 6q | -47.2%-$2.9M |
| 22NW, LP | $3.1M | 113,840 | 2.93% | 6q | -74.4%-$8.9M |
| Swiss National Bank | $3.0M | 111,600 | 0.00% | 5q | +23.9%+$580.1K |
| Ishara Investments LP | $2.8M | 102,500 | 2.03% | 2q | +25.0%+$553.1K |
| MARK ASSET MANAGEMENT LP | $2.7M | 101,289 | 0.18% | 2q | -30.1%-$1.2M |
| ExodusPoint Capital Management, LP | $2.7M | 101,052 | 0.02% | new | NEW |
| Timothy G. Youngquist 2020 Irrevocable Trust | $2.7M | 100,869 | 0.53% | new | NEW |
| CITIGROUP INC | $2.7M | 99,332 | 0.00% | 13q | +558.5%+$2.3M |
| Schonfeld Strategic Advisors LLC | $2.6M | 95,242 | 0.01% | 6q | -46.4%-$2.2M |
| ALPS ADVISORS INC | $2.4M | 88,976 | 0.01% | 3q | +38.1%+$662.5K |
| Squarepoint Ops LLC | $2.3M | 86,327 | 0.00% | 5q | -18.2%-$517.0K |
| HighVista Strategies LLC | $2.3M | 86,085 | 0.53% | 5q | +84.0%+$1.1M |
| BlueCrest Capital Management Ltd | $2.3M | 85,157 | 0.08% | new | NEW |
| KVP Capital Advisors, LP | $2.3M | 84,168 | 1.67% | new | NEW |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | $2.1M | 79,199 | 0.00% | 6q | HELD |
| Rafferty Asset Management, LLC | $2.1M | 78,186 | 0.00% | 5q | -17.1%-$436.3K |
| STATE OF WISCONSIN INVESTMENT BOARD | $2.0M | 73,265 | 0.00% | 6q | +14.2%+$246.2K |
| RHUMBLINE ADVISERS | $1.9M | 70,205 | 0.00% | 14q | +22.2%+$344.3K |
| Hennion & Walsh Asset Management, Inc. | $1.9M | 69,580 | 0.05% | 5q | -0.9%-$16.4K |
| Verition Fund Management LLC | $1.9M | 69,464 | 0.00% | 4q | -27.0%-$692.3K |
Five percent filings
Anyone crossing 5% of a company must say so within days - far sooner than the next quarterly holdings report. A 13D declares an intent to influence the company; a 13G is the passive version. See all activist filings →
| Filed | Form | Filer | % of class |
|---|---|---|---|
| 2026-08-06 | 13G/A | FMR LLCwith 1 co-filers | 5.1% |
Quarter by quarter
Coverage begins with the quarter ending 2018-12-31. Earlier filings exist only as occasional late amendments, too sparse to describe a market, so they are not shown.
| Quarter | Holders | Value | Shares | New | Added | Trimmed | Options |
|---|---|---|---|---|---|---|---|
| Q2 2026 | 219 | $2.7B | 98,543,863 | 35 | 83 | 62 | 2.9% |
| Q1 2026 | 208 | $2.6B | 89,700,158 | 25 | 91 | 47 | 7.8% |
| Q4 2025 | 216 | $3.5B | 86,666,659 | 44 | 76 | 69 | 9.2% |
| Q3 2025 | 186 | $3.0B | 79,406,988 | 43 | 65 | 57 | 0.7% |
| Q2 2025 | 156 | $884.8M | 65,312,471 | 36 | 70 | 28 | 0.1% |
| Q1 2025 | 144 | $979.3M | 60,767,325 | 54 | 48 | 25 | 1.5% |
| Q4 2024 | 104 | $571.8M | 46,448,175 | 12 | 38 | 15 | 0.0% |
| Q3 2024 | 100 | $540.3M | 44,397,988 | 16 | 36 | 22 | 0.0% |
| Q2 2024 | 89 | $519.9M | 44,413,850 | 13 | 46 | 12 | 0.0% |
| Q1 2024 | 84 | $552.3M | 42,761,598 | 16 | 23 | 30 | 0.0% |
| Q4 2023 | 79 | $302.2M | 35,141,978 | 17 | 35 | 11 | 0.0% |
| Q3 2023 | 72 | $249.6M | 26,249,868 | 20 | 23 | 10 | 0.0% |
| Q2 2023 | 65 | $425.9M | 24,989,432 | 11 | 27 | 8 | 0.0% |
| Q1 2023 | 60 | $382.1M | 24,400,880 | 60 | 0 | 0 | 0.0% |