Q32 BIO INC (QTTB)
Institutional ownership reported to the SEC as of Q2 2026, across 10 quarters.
70
Reporting holders
$282.7M
Reported value
73.7%
Of shares outstanding
1.2%
Held as options
+19
Holder change
Institutions report 21,926,815 shares against 29,769,466 outstanding. Shares only - option lines are excluded, which is why this can be compared with the company at all. The count comes from the cover page of the company's own most recent report, so it is dated when that was filed rather than at quarter end.
Options share is the part of reported value carried in derivative lines rather than shares. A high figure means institutions are expressing a view on this security without owning much of it.
Holders
| Filer | Value | Shares | Their book | Held | Change |
|---|---|---|---|---|---|
| ORBIMED ADVISORS LLC | $52.6M | 4,127,987 | 0.97% | 10q | +83.2%+$23.9M |
| Boxer Capital Management, LLC | $40.1M | 3,149,310 | 3.02% | new | NEW |
| Atlas Venture Life Science Advisors, LLC | $34.6M | 2,717,106 | 3.93% | 10q | +29.9%+$8.0M |
| BVF INC/IL | $29.9M | 2,350,000 | 0.77% | new | NEW |
| RA CAPITAL MANAGEMENT, L.P. | $29.7M | 2,332,457 | 0.26% | new | NEW |
| Point72 Asset Management, L.P. | $14.9M | 1,173,396 | 0.02% | new | NEW |
| Opaleye Management Inc. | $11.9M | 931,000 | 1.07% | 3q | -25.9%-$4.1M |
| Logos Global Management LP | $10.2M | 800,000 | 0.44% | new | NEW |
| SummitTX Capital, L.P. | $9.3M | 733,774 | 0.24% | new | NEW |
| Ikarian Capital, LLC | $8.0M | 430,000 | 0.86% | new | NEW |
| VANGUARD CAPITAL MANAGEMENT LLC | $6.6M | 518,803 | 0.00% | 2q | +69.3%+$2.7M |
| Woodline Partners LP | $3.6M | 286,212 | 0.01% | new | NEW |
| AMERICAN CENTURY COMPANIES INC | $3.5M | 272,752 | 0.00% | 2q | +1353.1%+$3.2M |
| Sanofi | $3.1M | 244,083 | 0.58% | 7q | HELD |
| ACORN CAPITAL ADVISORS, LLC | $2.8M | 216,171 | 0.75% | 7q | -31.4%-$1.3M |
| BOOTHBAY FUND MANAGEMENT, LLC | $2.4M | 130,427 | 0.03% | new | NEW |
| RENAISSANCE TECHNOLOGIES LLC | $2.3M | 179,600 | 0.00% | 5q | -13.2%-$348.0K |
| JANE STREET GROUP, LLC | $2.1M | 162,747 | 0.00% | 3q | +148.1%+$1.2M |
| MONIMUS CAPITAL MANAGEMENT, LP | $1.7M | 132,036 | 0.39% | 2q | -1.7%-$29.0K |
| GEODE CAPITAL MANAGEMENT, LLC | $1.6M | 122,690 | 0.00% | 10q | +3.8%+$57.8K |
| CITADEL ADVISORS LLC | $1.5M | 120,663 | 0.00% | 5q | +679.4%+$1.3M |
| BlackRock, Inc. | $1.5M | 118,507 | 0.00% | 8q | +37.6%+$412.3K |
| MARSHALL WACE, LLP | $854.2K | 67,045 | 0.00% | 2q | +27.9%+$186.1K |
| VANGUARD FIDUCIARY TRUST CO | $843.6K | 66,217 | 0.00% | 2q | +32.4%+$206.7K |
| Carlyle Group Inc. | $769.0K | 60,363 | 0.01% | 10q | -94.5%-$13.3M |
| STATE STREET CORP | $665.2K | 52,214 | 0.00% | 9q | +25.8%+$136.3K |
| TWO SIGMA INVESTMENTS, LP | $631.7K | 49,582 | 0.00% | 4q | +17.1%+$92.2K |
| Quadrature Capital Ltd | $463.7K | 36,396 | 0.00% | new | NEW |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | $441.0K | 34,613 | 0.01% | 2q | +174.4%+$280.3K |
| DAFNA Capital Management LLC | $419.1K | 32,896 | 0.08% | new | NEW |
| Knott David M Jr | $387.4K | 30,412 | 0.20% | new | NEW |
| Affinity Asset Advisors, LLC | $353.9K | 27,777 | 0.02% | 10q | HELD |
| Squarepoint Ops LLC | $303.1K | 23,790 | 0.00% | new | NEW |
| NORTHERN TRUST CORP | $301.1K | 23,631 | 0.00% | 8q | -5.6%-$17.9K |
| DIMENSIONAL FUND ADVISORS LP | $300.5K | 23,588 | 0.00% | new | NEW |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $297.4K | 23,342 | 0.00% | new | NEW |
| MANGROVE PARTNERS IM, LLC | $282.2K | 22,150 | 0.02% | new | NEW |
| LPL Financial LLC | $231.5K | 18,170 | 0.00% | new | NEW |
| UBS Group AG | $191.2K | 15,008 | 0.00% | 10q | +5458.5%+$187.8K |
| Balyasny Asset Management L.P. | $157.2K | 12,342 | 0.00% | new | NEW |
| ExodusPoint Capital Management, LP | $144.4K | 11,336 | 0.00% | new | NEW |
| MILLENNIUM MANAGEMENT LLC | $139.2K | 10,928 | 0.00% | new | NEW |
| XTX Topco Ltd | $138.5K | 10,874 | 0.00% | new | NEW |
| MORGAN STANLEY | $82.3K | 6,456 | 0.00% | 10q | -32.5%-$39.5K |
| Vanguard Global Advisers, LLC | $61.5K | 4,824 | 0.00% | 2q | +151.9%+$37.1K |
| FMR LLC | $43.2K | 3,388 | 0.00% | 10q | HELD |
| CITIGROUP INC | $36.8K | 2,888 | 0.00% | new | NEW |
| Private Wealth Asset Management, LLC | $21.7K | 1,700 | 0.00% | new | NEW |
| Arax Advisory Partners | $14.2K | 1,111 | 0.00% | 5q | -3.2% |
| FEDERATED HERMES, INC. | $13.4K | 1,050 | 0.00% | 8q | -53.8%-$15.6K |
| Rockefeller Capital Management L.P. | $7.4K | 577 | 0.00% | 4q | HELD |
| JONES FINANCIAL COMPANIES LLLP | $6.6K | 500 | 0.00% | 3q | HELD |
| Russell Investments Group, Ltd. | $5.8K | 454 | 0.00% | 8q | HELD |
| BNP PARIBAS FINANCIAL MARKETS | $3.9K | 303 | 0.00% | 9q | HELD |
| EverSource Wealth Advisors, LLC | $3.1K | 240 | 0.00% | 7q | -94.8%-$56.1K |
| ACADIAN ASSET MANAGEMENT LLC | $2.8K | 218,234 | 0.00% | 6q | +26.4% |
| SIMPLEX TRADING, LLC | $2.5K | options only | 0.00% | new | OPTIONS |
| NISA INVESTMENT ADVISORS, LLC | $2.1K | 166 | 0.00% | 5q | HELD |
| Truvestments Capital LLC | $2.1K | 162 | 0.00% | new | NEW |
| OSAIC HOLDINGS, INC. | $1.6K | 124 | 0.00% | 10q | HELD |
| Allworth Financial LP | $1.4K | 108 | 0.00% | 7q | +10.2% |
| SBI Securities Co., Ltd. | $1.2K | 94 | 0.00% | 7q | -9.6% |
| Federation des caisses Desjardins du Quebec | $888 | 70 | 0.00% | 10q | HELD |
| Clearstead Advisors, LLC | $854 | 67 | 0.00% | new | NEW |
| Caitong International Asset Management Co., Ltd | $573 | 45 | 0.00% | new | NEW |
| Cambridge Investment Research Advisors, Inc. | $460 | 36,162 | 0.00% | 2q | +3.2% |
| GROUP ONE TRADING LLC | $433 | 34 | 0.00% | 4q | HELD |
| HRT FINANCIAL LP | $203 | 15,949 | 0.00% | new | NEW |
| HARBOUR INVESTMENTS, INC. | $140 | 11 | 0.00% | 9q | HELD |
| MERCER GLOBAL ADVISORS INC /ADV | $25 | 2 | 0.00% | new | NEW |
| AdvisorNet Financial, Inc | $25 | 2 | 0.00% | 10q | HELD |
| DANSKE BANK A/S | $13 | 1 | 0.00% | 8q | HELD |
| ROYAL BANK OF CANADA | $0 | 43 | 0.00% | 10q | -98.4% |
Five percent filings
Anyone crossing 5% of a company must say so within days - far sooner than the next quarterly holdings report. A 13D declares an intent to influence the company; a 13G is the passive version. See all activist filings →
| Filed | Form | Filer | % of class |
|---|---|---|---|
| 2026-08-14 | 13G/A | Sirenia Capital Management LPwith 1 co-filers | 0.0% |
| 2026-08-14 | 13G/A | Point72 Asset Management, L.P.with 2 co-filers | 5.0% |
| 2026-07-31 | 13G/A | Opaleye Management Inc.with 2 co-filers | 5.5% |
| 2026-07-20 | 13D/A | ORBIMED ADVISORS LLCwith 2 co-filers | 13.9% |
| 2026-07-10 | 13G | Boxer Capital Management, LLCwith 3 co-filers | 13.3% |
| 2026-07-06 | 13G/A | The Carlyle Group Inc.with 9 co-filers | 4.1% |
Quarter by quarter
Coverage begins with the quarter ending 2018-12-31. Earlier filings exist only as occasional late amendments, too sparse to describe a market, so they are not shown.
| Quarter | Holders | Value | Shares | New | Added | Trimmed | Options |
|---|---|---|---|---|---|---|---|
| Q2 2026 | 70 | $282.7M | 21,926,815 | 28 | 16 | 12 | 1.2% |
| Q1 2026 | 51 | $59.3M | 9,221,361 | 8 | 13 | 8 | 0.0% |
| Q4 2025 | 49 | $26.4M | 7,970,775 | 7 | 7 | 19 | 0.0% |
| Q3 2025 | 50 | $16.5M | 8,384,029 | 6 | 8 | 17 | 0.0% |
| Q2 2025 | 60 | $13.3M | 8,949,663 | 9 | 10 | 18 | 0.1% |
| Q1 2025 | 72 | $15.5M | 9,372,116 | 7 | 15 | 19 | 0.1% |
| Q4 2024 | 92 | $38.4M | 10,995,153 | 32 | 21 | 9 | 1.4% |
| Q3 2024 | 72 | $406.0M | 9,111,893 | 26 | 18 | 8 | 0.0% |
| Q2 2024 | 54 | $144.2M | 8,067,739 | 18 | 16 | 6 | 0.0% |
| Q1 2024 | 38 | $126.1M | 7,428,092 | 38 | 0 | 0 | 0.2% |