CYTOKINETICS INC (CYTK)
Institutional ownership reported to the SEC as of Q2 2026, across 31 quarters.
462
Reporting holders
$12.7B
Reported value
101.0%
Of shares outstanding
5.8%
Held as options
+34
Holder change
Institutions report 140,467,457 shares against 139,023,418 outstanding. Shares only - option lines are excluded, which is why this can be compared with the company at all. The count comes from the cover page of the company's own most recent report, so it is dated when that was filed rather than at quarter end. Over 100% because an adviser and a sub-adviser can both report the same shares, and both are counted.
Options share is the part of reported value carried in derivative lines rather than shares. A high figure means institutions are expressing a view on this security without owning much of it.
Holders
| Filer | Value | Shares | Their book | Held | Change |
|---|---|---|---|---|---|
| BlackRock, Inc. | $1.7B | 20,094,362 | 0.03% | 8q | +21.4%+$302.1M |
| WELLINGTON MANAGEMENT GROUP LLP | $590.5M | 6,931,770 | 0.10% | 25q | -13.5%-$91.8M |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $571.8M | 6,711,799 | 0.03% | 2q | +14.9%+$73.9M |
| STATE STREET CORP | $553.2M | 6,494,233 | 0.02% | 31q | +13.0%+$63.8M |
| VANGUARD CAPITAL MANAGEMENT LLC | $521.2M | 6,117,515 | 0.01% | 2q | +11.5%+$53.6M |
| FMR LLC | $428.7M | 5,031,782 | 0.02% | 31q | -53.1%-$484.8M |
| Avoro Capital Advisors LLC | $425.9M | 4,999,999 | 3.82% | 2q | +50.0%+$142.0M |
| BANK OF AMERICA CORP /DE/ | $394.9M | 4,635,709 | 0.03% | 31q | +48.3%+$128.7M |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $317.7M | 1,549,458 | 0.02% | 31q | +72.4%+$133.4M |
| GEODE CAPITAL MANAGEMENT, LLC | $316.3M | 3,712,501 | 0.02% | 31q | +15.5%+$42.4M |
| RTW INVESTMENTS, LP | $243.8M | 2,862,003 | 2.08% | 24q | +5.2%+$12.0M |
| ARMISTICE CAPITAL, LLC | $232.7M | 1,201,342 | 2.85% | 10q | +57.1%+$84.6M |
| Polar Capital Holdings Plc | $192.0M | 2,253,649 | 0.45% | 23q | +35.7%+$50.5M |
| CITADEL ADVISORS LLC | $167.5M | 640,945 | 0.02% | 31q | -41.7%-$120.0M |
| Royalty Pharma Sub-Manager, LLC | $167.0M | 1,960,784 | 34.52% | 3q | HELD |
| GOLDMAN SACHS GROUP INC | $152.9M | 1,761,588 | 0.01% | 31q | -20.1%-$38.5M |
| Capital Research Global Investors | $143.7M | 1,686,625 | 0.02% | 2q | +118.8%+$78.0M |
| JPMORGAN CHASE & CO | $142.2M | 1,588,895 | 0.01% | 31q | +75.8%+$61.3M |
| NORTHERN TRUST CORP | $140.3M | 1,647,345 | 0.02% | 31q | +14.3%+$17.5M |
| WILLIAM BLAIR INVESTMENT MANAGEMENT, LLC | $136.6M | 1,603,442 | 0.41% | 2q | +47.4%+$43.9M |
| Integral Health Asset Management, LLC | $136.3M | 1,600,000 | 5.38% | 26q | HELD |
| Point72 Asset Management, L.P. | $135.3M | 1,587,712 | 0.15% | 13q | +153.6%+$82.0M |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $133.4M | 1,565,781 | 0.02% | 31q | +12.1%+$14.4M |
| Sixth Street Partners Management Company, L.P. | $133.4M | 1,565,781 | 0.02% | new | NEW |
| MORGAN STANLEY | $128.7M | 1,510,318 | 0.01% | 35q | HELD |
| PRINCIPAL FINANCIAL GROUP INC | $111.7M | 1,311,664 | 0.05% | 31q | +20.0%+$18.6M |
| Capital International Investors | $111.2M | 1,305,848 | 0.02% | 7q | -2.5%-$2.8M |
| Invesco Ltd. | $105.2M | 1,235,323 | 0.01% | 31q | +154.7%+$63.9M |
| UBS Group AG | $99.8M | 1,171,287 | 0.01% | 31q | -43.6%-$77.2M |
| Pictet Asset Management Holding SA | $99.0M | 1,160,463 | 0.09% | 12q | +54.5%+$34.9M |
| Frazier Life Sciences Management, L.P. | $98.8M | 1,159,879 | 2.15% | 5q | HELD |
| Bank of New York Mellon Corp | $98.0M | 1,150,697 | 0.02% | 31q | +14.4%+$12.3M |
| Holocene Advisors, LP | $97.5M | 1,144,579 | 0.22% | new | NEW |
| Woodline Partners LP | $93.8M | 1,100,708 | 0.29% | 9q | +10.0%+$8.5M |
| D. E. Shaw & Co., Inc. | $89.3M | 1,048,103 | 0.04% | 10q | +48.3%+$29.1M |
| NORGES BANK | $86.5M | 1,015,522 | 0.01% | 16q | +25.8%+$17.8M |
| NOMURA ASSET MANAGEMENT INTERNATIONAL INC. | $81.9M | 961,815 | 0.12% | 3q | +1883.8%+$77.8M |
| VANGUARD FIDUCIARY TRUST CO | $77.2M | 906,423 | 0.02% | 2q | +13.4%+$9.1M |
| FRANKLIN RESOURCES INC | $75.9M | 891,087 | 0.02% | 20q | +117.5%+$41.0M |
| JANE STREET GROUP, LLC | $72.9M | 6,084 | 0.01% | 27q | HELD |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | $70.5M | 827,810 | 0.07% | 23q | +15.9%+$9.7M |
| GROUP ONE TRADING LLC | $67.3M | options only | 0.09% | 31q | OPTIONS |
| Melqart Asset Management (UK) Ltd | $65.4M | 767,525 | 6.22% | 10q | -9.1%-$6.5M |
| Siren, L.L.C. | $64.7M | 758,952 | 1.31% | 2q | +23.6%+$12.4M |
| Fisher Asset Management, LLC | $63.4M | 743,697 | 0.02% | 11q | -3.2%-$2.1M |
| Balyasny Asset Management L.P. | $62.3M | 711,676 | 0.08% | 4q | -28.3%-$24.6M |
| Foresite Capital Management IV, LLC | $60.9M | 714,695 | 20.98% | 4q | +42.0%+$18.0M |
| Deep Track Capital, LP | $59.6M | 700,000 | 0.87% | 9q | -49.1%-$57.4M |
| BNP PARIBAS FINANCIAL MARKETS | $58.7M | 689,077 | 0.02% | 31q | -19.3%-$14.1M |
| Nationale-Nederlanden Powszechne Towarzystwo Emerytalne S.A. | $56.3M | 660,310 | 3.08% | 7q | HELD |
| Qube Research & Technologies Ltd | $48.8M | 572,535 | 0.05% | 7q | -26.5%-$17.6M |
| BROWN ADVISORY INC | $48.6M | 570,664 | 0.08% | 10q | -7.2%-$3.7M |
| EVENTIDE ASSET MANAGEMENT, LLC | $48.1M | 564,398 | 0.64% | 15q | +17.8%+$7.3M |
| Affinity Asset Advisors, LLC | $46.9M | 550,000 | 2.12% | 4q | -21.5%-$12.8M |
| MASSACHUSETTS FINANCIAL SERVICES CO /MA/ | $46.8M | 549,348 | 0.01% | 9q | +76.3%+$20.2M |
| FEDERATED HERMES, INC. | $45.8M | 538,022 | 0.07% | 10q | -23.1%-$13.8M |
| First Turn Management, LLC | $44.9M | 527,412 | 4.81% | 4q | +85.9%+$20.8M |
| AMERICAN CENTURY COMPANIES INC | $44.2M | 518,398 | 0.02% | 20q | +16.8%+$6.3M |
| Caption Management, LLC | $43.7M | options only | 0.20% | 12q | OPTIONS |
| Checkpoint Capital L.P. | $40.5M | 475,000 | 10.38% | 4q | +163.9%+$25.1M |
| Hood River Capital Management LLC | $40.0M | 469,273 | 0.29% | new | NEW |
| EMERALD ADVISERS, LLC | $39.0M | 457,956 | 0.92% | 2q | +130.3%+$22.1M |
| ADAR1 Capital Management, LLC | $39.0M | 457,907 | 1.79% | 11q | -27.6%-$14.9M |
| AMERIPRISE FINANCIAL INC | $38.7M | 454,851 | 0.01% | 31q | -24.9%-$12.8M |
| MARSHALL WACE, LLP | $38.5M | 451,467 | 0.03% | 19q | -31.2%-$17.5M |
| Nuveen, LLC | $38.1M | 447,185 | 0.01% | 6q | +27.1%+$8.1M |
| Candriam S.C.A. | $37.7M | 443,066 | 0.17% | 3q | +32.2%+$9.2M |
| RHUMBLINE ADVISERS | $35.9M | 421,799 | 0.03% | 31q | +14.1%+$4.4M |
| ALLIANCEBERNSTEIN L.P. | $35.3M | 535,993 | 0.01% | 31q | +16.8%+$5.1M |
| GILDER GAGNON HOWE & CO LLC | $34.1M | 400,245 | 0.35% | 16q | +20.9%+$5.9M |
| TD Asset Management Inc | $32.8M | 385,130 | 0.03% | 19q | -8.5%-$3.0M |
| CITIGROUP INC | $32.3M | 322,932 | 0.01% | 31q | +29.6%+$7.4M |
| VOYA INVESTMENT MANAGEMENT LLC | $31.4M | 368,698 | 0.03% | 31q | +42.1%+$9.3M |
| GSK plc | $29.0M | 340,434 | 4.82% | 3q | HELD |
| SPHERA FUNDS MANAGEMENT LTD. | $27.3M | 219,987 | 3.56% | 12q | +452.5%+$22.3M |
| TWO SIGMA INVESTMENTS, LP | $27.0M | 317,411 | 0.02% | 3q | +11.4%+$2.8M |
| BANK OF MONTREAL /CAN/ | $26.0M | 285,688 | 0.01% | 31q | +1855.2%+$24.7M |
| E. Ohman J:or Asset Management AB | $25.9M | 304,611 | 0.60% | 6q | +1.3%+$327.9K |
| Russell Investments Group, Ltd. | $25.7M | 301,566 | 0.02% | 27q | +73.3%+$10.9M |
| Trails Edge Capital Partners, LP | $24.5M | 288,089 | 3.90% | 2q | -4.0%-$1.0M |
| EMERALD MUTUAL FUND ADVISERS TRUST | $23.8M | 279,769 | 0.84% | 2q | +106.5%+$12.3M |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | $23.3M | 273,031 | 0.00% | 31q | +13.5%+$2.8M |
| Walleye Capital LLC | $23.1M | 239,728 | 0.08% | 6q | HELD |
| Polaris Capital Management, LLC | $22.7M | 266,900 | 2.14% | new | NEW |
| SEGALL BRYANT & HAMILL, LLC | $21.9M | 257,063 | 0.26% | 9q | +42.7%+$6.5M |
| Alyeska Investment Group, L.P. | $21.3M | 250,000 | 0.05% | 2q | +66.7%+$8.5M |
| ExodusPoint Capital Management, LP | $21.2M | 249,259 | 0.14% | 3q | +377.3%+$16.8M |
| Capital World Investors | $21.2M | 248,815 | 0.00% | 2q | +2.8%+$577.1K |
| TUDOR INVESTMENT CORP ET AL | $21.1M | 92,680 | 0.03% | 4q | HELD |
| Jupiter Topco LLC | $20.8M | 244,417 | 0.01% | new | FIRST |
| Sarissa Capital Management LP | $19.5M | 228,623 | 10.95% | 10q | HELD |
| Swiss National Bank | $18.9M | 222,400 | 0.01% | 31q | -3.2%-$630.4K |
| DEUTSCHE BANK AG\ | $18.4M | 216,540 | 0.01% | 34q | +15.7%+$2.5M |
| PRUDENTIAL FINANCIAL INC | $18.3M | 214,535 | 0.02% | 31q | +261.0%+$13.2M |
| BAKER BROS. ADVISORS LP | $18.0M | 211,267 | 0.09% | new | NEW |
| California Public Employees Retirement System | $18.0M | 211,052 | 0.01% | 16q | +6.3%+$1.1M |
| MILLENNIUM MANAGEMENT LLC | $17.9M | 109,717 | 0.01% | 31q | +12.0%+$1.9M |
| Nicholas Investment Partners, LP | $17.8M | 209,071 | 1.00% | 4q | +199.3%+$11.9M |
| PINNACLE ASSOCIATES LTD | $17.2M | 202,440 | 0.19% | 31q | +14.3%+$2.2M |
| Mirador Capital Partners LP | $17.2M | 202,370 | 2.11% | 27q | HELD |
Five percent filings
Anyone crossing 5% of a company must say so within days - far sooner than the next quarterly holdings report. A 13D declares an intent to influence the company; a 13G is the passive version. See all activist filings →
| Filed | Form | Filer | % of class |
|---|---|---|---|
| 2026-08-13 | 13G/A | Wellington Management Group LLPwith 2 co-filers | 5.1% |
| 2026-07-08 | 13G/A | FMR LLCwith 1 co-filers | 3.9% |
Quarter by quarter
Coverage begins with the quarter ending 2018-12-31. Earlier filings exist only as occasional late amendments, too sparse to describe a market, so they are not shown.
| Quarter | Holders | Value | Shares | New | Added | Trimmed | Options |
|---|---|---|---|---|---|---|---|
| Q2 2026 | 462 | $12.7B | 140,467,457 | 87 | 216 | 94 | 5.8% |
| Q1 2026 | 428 | $9.2B | 127,496,105 | 75 | 160 | 123 | 8.4% |
| Q4 2025 | 407 | $8.1B | 118,834,589 | 82 | 132 | 121 | 7.3% |
| Q3 2025 | 360 | $7.0B | 119,328,055 | 98 | 109 | 98 | 6.3% |
| Q2 2025 | 292 | $4.1B | 117,278,772 | 28 | 133 | 93 | 6.2% |
| Q1 2025 | 328 | $5.2B | 123,076,072 | 50 | 127 | 96 | 4.3% |
| Q4 2024 | 324 | $5.8B | 116,880,068 | 29 | 102 | 119 | 4.6% |
| Q3 2024 | 320 | $6.9B | 123,537,811 | 38 | 122 | 87 | 6.0% |
| Q2 2024 | 324 | $7.1B | 125,005,573 | 38 | 134 | 91 | 4.4% |
| Q1 2024 | 361 | $8.6B | 110,206,297 | 87 | 118 | 103 | 10.8% |
| Q4 2023 | 331 | $11.1B | 107,601,520 | 110 | 63 | 97 | 19.1% |
| Q3 2023 | 220 | $3.1B | 102,563,478 | 22 | 84 | 65 | 2.7% |
| Q2 2023 | 216 | $3.2B | 98,895,173 | 22 | 82 | 60 | 0.6% |
| Q1 2023 | 221 | $3.9B | 110,183,694 | 34 | 62 | 75 | 0.5% |
| Q4 2022 | 211 | $4.3B | 92,841,536 | 25 | 86 | 60 | 1.3% |
| Q3 2022 | 283 | $5.1B | 104,640,679 | 39 | 109 | 81 | 1.2% |
| Q2 2022 | 267 | $4.2B | 105,962,147 | 49 | 99 | 69 | 0.9% |
| Q1 2022 | 240 | $3.5B | 95,541,183 | 20 | 93 | 82 | 0.5% |
| Q4 2021 | 251 | $4.2B | 91,624,447 | 48 | 77 | 75 | 0.5% |
| Q3 2021 | 214 | $3.2B | 90,256,628 | 51 | 94 | 41 | 0.7% |
| Q2 2021 | 189 | $1.5B | 75,598,374 | 23 | 59 | 60 | 1.0% |
| Q1 2021 | 190 | $1.7B | 74,834,886 | 30 | 58 | 61 | 0.5% |
| Q4 2020 | 181 | $1.5B | 72,981,036 | 31 | 55 | 57 | 1.6% |
| Q3 2020 | 185 | $1.6B | 68,820,682 | 45 | 85 | 36 | 7.1% |
| Q2 2020 | 162 | $1.4B | 57,903,070 | 30 | 60 | 48 | 1.0% |
| Q1 2020 | 150 | $680.7M | 55,741,078 | 26 | 56 | 40 | 3.4% |
| Q4 2019 | 142 | $597.9M | 55,822,602 | 24 | 50 | 40 | 0.9% |
| Q3 2019 | 148 | $517.8M | 45,120,017 | 20 | 53 | 36 | 2.3% |
| Q2 2019 | 135 | $515.3M | 44,898,046 | 17 | 67 | 24 | 4.0% |
| Q1 2019 | 135 | $324.8M | 40,008,462 | 15 | 60 | 26 | 2.4% |
| Q4 2018 | 133 | $255.8M | 40,338,714 | 4 | 3 | 1 | 0.3% |