HolderBook

TCG Crossover Management, LLC

Reported holdings as of Q2 2026, from 19 quarterly filings.

CIK
1839948
Reported value
$4.2B
Positions
54
Top 10 weight
57.4%
Filed
2026-08-14
Days after quarter end
45

Holdings

SecurityTickerValue SharesWeightWeight change Held Change
ABIVAX SAABVX$800.6M6,007,83419.24%-1.40pp11q-7.3%-$63.1M
TANGO THERAPEUTICS INCTNGX$283.9M9,081,2016.82%+0.52pp7q-13.8%-$45.3M
CG ONCOLOGY INCCGON$260.8M3,670,2066.27%-0.84pp10qHELD
COGENT BIOSCIENCES INCCOGT$187.9M4,854,4364.52%-0.93pp19q-1.9%-$3.6M
IMMUNOVANT INCIMVT$171.8M4,457,9884.13%+0.96pp3qHELD
SPYRE THERAPEUTICS INCSYRE$168.7M1,900,5824.06%+1.31pp4qHELD
DIANTHUS THERAPEUTICS INCDNTH$163.4M1,676,6243.93%-0.10pp7qHELD
MIRUM PHARMACEUTICALS INCMIRM$124.3M1,062,0492.99%+0.18pp3qHELD
ZAI LAB LTDZLAB$116.6M6,137,6272.80%-newNEW
AMYLYX PHARMACEUTICALS INCAMLX$112.1M6,243,8122.70%+0.21pp8qHELD
MONTE ROSA THERAPEUTICS INCGLUE$111.9M4,622,1512.69%+0.51pp3qHELD
BIOCRYST PHARMACEUTICALS INCBCRX$110.2M11,020,9682.65%-0.35pp2qHELD
VOR BIOPHARMA INCVOR$104.4M5,673,0782.51%-0.25pp2qHELD
TYRA BIOSCIENCES INCTYRA$103.8M3,248,9802.49%-1.07pp19qHELD
DYNE THERAPEUTICS INCDYN$102.5M4,615,1442.46%+0.07pp14qHELD
DISC MEDICINE INCIRON$98.1M1,341,8622.36%-0.10pp2qHELD
RELAY THERAPEUTICS INCRLAY$80.0M4,273,3561.92%+0.71pp4qHELD
SAVARA INCSVRA$76.2M12,362,2051.83%-0.10pp12qHELD
AURA BIOSCIENCES INCAURA$67.7M9,533,3331.63%-newNEW
REVOLUTION MEDICINES INCRVMD$63.8M340,8991.53%-0.07pp4q-40.9%-$44.1M
FIRST TRACKS BIOTHERAPEUTICSTRAX$58.3M2,895,3041.40%-newNEW
KODIAK SCIENCES INCKOD$56.3M1,445,5381.35%-0.22pp11qHELD
AVALO THERAPEUTICS INCAVTX$55.8M3,017,1201.34%+1.02pp8q+308.6%+$42.1M
LB PHARMACEUTICALS INCLBRX$47.0M1,447,3101.13%-0.17pp4q-21.3%-$12.7M
CENTURY THERAPEUTICS INCIPSC$43.4M17,754,4301.04%-0.07pp2qHELD
TECTONIC THERAPEUTIC INCTECX$41.4M1,204,8911.00%-0.07pp2qHELD
XENCOR INCXNCR$39.5M2,452,1380.95%+0.10pp8qHELD
SURROZEN INCSRZN$38.2M1,473,1010.92%-0.31pp2qHELD
EDITAS MEDICINE INCEDIT$36.0M11,111,1110.87%-newNEW
MBX BIOSCIENCES INCMBX$35.9M650,0000.86%+0.31pp8qHELD
PHARVARIS N VPHVS$34.9M1,008,2290.84%-newNEW
SILENCE THERAPEUTICS PLCSLN$33.3M3,033,5600.80%+0.34pp16qHELD
INFLARX NVIFRX$32.5M14,500,0000.78%-newNEW
ALTIMMUNE INCALT$30.4M10,000,0000.73%-newNEW
JANUX THERAPEUTICS INCJANX$27.5M1,789,6170.66%-0.05pp3qHELD
PERSPECTIVE THERAPEUTICS INCCATX$27.0M7,915,5670.65%-0.30pp2qHELD
AGOMAB THERAPEUTICS NVAGMB$26.7M2,053,2330.64%+0.02pp2qHELD
BIOHAVEN LTDBHVN$26.5M1,779,9520.64%-0.48pp3q-61.6%-$42.4M
AKTIS ONCOLOGY INCAKTS$22.5M696,5600.54%-newNEW
ALECTOR INCALEC$20.1M10,000,0000.48%-0.13pp3qHELD
FORTE BIOSCIENCES INCFBRX$19.6M920,0000.47%-newNEW
MONOPAR THERAPEUTICS INCMNPR$18.8M203,3270.45%+0.25pp4q+53.9%+$6.6M
OCULAR THERAPEUTIX INCOCUL$16.2M1,647,7520.39%-0.01pp10qHELD
ADC THERAPEUTICS SAADCT$12.2M11,390,1750.29%-0.93pp4qHELD
ALX ONCOLOGY HLDGS INCALXO$11.7M5,655,4870.28%-0.46pp2q-56.5%-$15.2M
ENTRADA THERAPEUTICS INCTRDA$7.8M1,060,2300.19%-0.64pp19q-53.7%-$9.0M
CULLINAN THERAPEUTICS INCCGEM$7.4M406,7860.18%+0.01pp2qHELD
ARVINAS INCARVN$5.9M707,0980.14%-0.58pp4q-70.4%-$14.0M
KORRO BIO INCKRRO$5.5M416,3010.13%flat4qHELD
RESEARCH ALLIANCE CORP IIIRACC$5.3M500,0000.13%-newNEW
LEONABIO INCLONA$4.3M464,3980.10%-0.03pp3qHELD
JATT II ACQUISITION CORP$2.3M200,0000.05%-newNEW
CONTEXT THERAPEUTICS INCCNTX$1.5M2,682,6960.04%-0.17pp2qHELD
EIKON THERAPEUTICS INCEIKN$494.6K37,9020.01%-newNEW

By sector

Industry comes from the SIC code on each company's own SEC filings, which is self-reported and sometimes out of date. Derivative exposure is counted with the shares. Securities the SEC assigns no industry - funds, trusts, foreign issues - are shown as not classified rather than dropped.

Biotech & Pharma 98.4%Not classified 1.6%
 
SectorValueShare
Biotech & Pharma$4.1B98.4%
Not classified$65.9M1.6%

Quarter by quarter

QuarterValuePositions NewAddedTrimmed ExitedTop 10 Days to file
Q2 2026$4.2B541229757.4%45
Q1 2026$3.5B4911810560.9%45
Q4 2025$3.0B43896564.3%48
Q3 2025$2.0B401175865.9%48
Q2 2025$875.5M37513556.3%45
Q1 2025$733.1M37022155.3%44
Q4 2024$1.0B38542352.0%45
Q3 2024$1.2B36924558.4%45
Q2 2024$959.5M32264364.7%45
Q1 2024$1.3B33957558.3%45
Q4 2023$901.7M29521261.3%45
Q3 2023$679.1M26832461.8%45
Q2 2023$609.8M22241280.7%45
Q1 2023$513.0M22335278.0%45
Q4 2022$566.6M21574579.5%45
Q3 2022$333.4M21345483.4%45
Q2 2022$235.4M22244080.2%46
Q1 2022$249.1M20572078.8%46
Q4 2021$213.6M15000083.5%49

Rows marked UNVERIFIED ID, PLACEHOLDER ID, TICKER AS ID or NON-CUSIP ID carry an identifier that is not a valid CUSIP. They are shown because the filer reported that money, but treat the security named with caution - hover the chip for what is wrong with it, and see the methodology.

Held counts consecutive filings in which this manager reported the position, and can reach further back than the quarters listed above: the tabs begin at Q4 2018 because earlier coverage is too sparse to describe a market, but tenure is counted over every filing we hold, some reaching to 2007. A position sold and later rebought starts again from one.

Weight change is the shift in this position's share of the whole book, in percentage points. It is the more useful column: when money flows into or out of a broad fund, almost every holding is bought or sold at once, so added and trimmed largely track flows. A weight that rose while the book shrank is a decision. Both compare with the previous quarter this filer reported, not the previous calendar quarter.