HolderBook

SILENCE THERAPEUTICS PLC (SLN)

Institutional ownership reported to the SEC as of Q2 2026, across 24 quarters.

69
Reporting holders
$260.0M
Reported value
16.6%
Of shares outstanding
2.9%
Held as options
+17
Holder change

Institutions report 23,503,824 shares against 141,740,037 outstanding. Shares only - option lines are excluded, which is why this can be compared with the company at all. The count comes from the cover page of the company's own most recent report, so it is dated when that was filed rather than at quarter end.

Options share is the part of reported value carried in derivative lines rather than shares. A high figure means institutions are expressing a view on this security without owning much of it.

Holders

FilerValueShares Their book Held Change
Siren, L.L.C.$36.4M3,311,4380.74%8q+13.7%+$4.4M
TCG Crossover Management, LLC$33.3M3,033,5600.80%16qHELD
Nantahala Capital Management, LLC$29.6M2,693,4620.49%10q+25.5%+$6.0M
Redmile Group, LLC$23.8M2,164,7771.60%10qHELD
CITADEL ADVISORS LLC$14.6M1,329,6250.00%4q+7.7%+$1.0M
Tetragon Partners GP Ltd$11.7M764,2561.84%3q+21.3%+$2.1M
Nextech Invest Ltd.$10.5M952,4000.50%6qHELD
MILLENNIUM MANAGEMENT LLC$10.0M909,2790.00%10q-15.4%-$1.8M
Soleus Capital Management, L.P.$6.9M630,0000.24%newNEW
Balyasny Asset Management L.P.$6.7M610,9800.01%newNEW
5AM Venture Management, LLC$5.2M476,2001.82%10qHELD
Caption Management, LLC$5.1M162,4760.02%newNEW
GREAT POINT PARTNERS LLC$4.9M450,0000.93%3q-55.9%-$6.3M
MORGAN STANLEY$4.4M403,1720.00%24q+515.7%+$3.7M
JANE STREET GROUP, LLC$4.3M369,1510.00%3q+265.8%+$3.1M
AMERIPRISE FINANCIAL INC$4.1M370,0520.00%newNEW
ADAR1 Capital Management, LLC$3.7M338,3730.17%11q+96.5%+$1.8M
SummitTX Capital, L.P.$3.6M326,6480.09%newNEW
Schonfeld Strategic Advisors LLC$3.0M269,3480.01%newNEW
UBS Group AG$2.7M243,1520.00%19q-1.5%-$41.6K
SUSQUEHANNA INTERNATIONAL GROUP, LLP$2.6M184,5190.00%3q+60.1%+$962.9K
Ishara Investments LP$2.4M55,3501.79%3q-60.6%-$3.7M
BlackRock, Inc.$2.4M219,9170.00%7q+7.4%+$166.2K
BANK OF MONTREAL /CAN/$2.2M201,7340.00%8q-0.6%-$12.8K
BOOTHBAY FUND MANAGEMENT, LLC$2.2M198,3470.03%10q-5.1%-$117.9K
Propel Bio Management, LLC$2.1M191,7331.10%newNEW
FRED ALGER MANAGEMENT, LLC$1.9M177,0000.01%newNEW
Ikarian Capital, LLC$1.8M830,7840.20%5q-4.0%-$77.0K
Qube Research & Technologies Ltd$1.8M163,9450.00%3q+56.8%+$652.1K
BNP PARIBAS FINANCIAL MARKETS$1.7M158,9500.00%7q+7.6%+$123.9K
GOLDMAN SACHS GROUP INC$1.7M155,9290.00%4q+196.9%+$1.1M
TWO SIGMA INVESTMENTS, LP$1.3M121,0040.00%10q+646.8%+$1.2M
HSBC HOLDINGS PLC$1.3M122,8340.00%19qHELD
Quadrature Capital Ltd$1.3M118,1290.01%newNEW
Squarepoint Ops LLC$1.3M115,9180.00%2q+29.6%+$290.4K
XTX Topco Ltd$1.2M107,5790.02%3q+1.5%+$17.3K
M28 Capital Management LP$1.1M101,2032.36%15qHELD
MARSHALL WACE, LLP$791.0K72,0390.00%10q-57.5%-$1.1M
Birchview Capital, LP$782.0K71,2180.37%newNEW
Seven Fleet Capital Management LP$660.0K60,1070.11%3q-61.7%-$1.1M
GEODE CAPITAL MANAGEMENT, LLC$324.3K29,5380.00%16qHELD
BANK OF AMERICA CORP /DE/$277.6K25,2800.00%14q-15.1%-$49.3K
Trexquant Investment LP$261.8K23,8420.00%newNEW
Verdad Advisers, LP$224.0K20,4000.21%newNEW
Scientech Research LLC$210.1K19,1330.17%newNEW
RENAISSANCE TECHNOLOGIES LLC$185.9K16,9300.00%newNEW
Arrowpoint Investment Partners (Singapore) Pte. Ltd.$179.3K16,3340.04%newNEW
Persistent Asset Partners Ltd$166.6K15,1700.05%newNEW
RAYMOND JAMES FINANCIAL INC$164.7K15,0000.00%3q-40.0%-$109.8K
RHUMBLINE ADVISERS$151.7K13,8150.00%12q-0.9%-$1.3K
SIMPLEX TRADING, LLC$148.2Koptions only0.00%5qOPTIONS
CITIGROUP INC$145.1K13,2170.00%19q+620.3%+$125.0K
AXQ CAPITAL, LP$138.0K12,5660.02%newNEW
GAMMA Investing LLC$121.5K11,0630.00%11q+18.1%+$18.6K
CenterBook Partners LP$114.4K10,4160.01%newNEW
China Universal Asset Management Co., Ltd.$82.1K7,4750.00%7q-10.3%-$9.4K
JPMORGAN CHASE & CO$41.7K3,8630.00%7q-49.4%-$40.7K
BARCLAYS PLC$37.5K3,4180.00%10q+16.4%+$5.3K
JONES FINANCIAL COMPANIES LLLP$25.4K2,5000.00%6qHELD
Mirae Asset Global Investments Co., Ltd.$23.1K2,1010.00%7q-57.1%-$30.7K
Tower Research Capital LLC (TRC)$18.0K1,6390.00%7q-29.1%-$7.4K
Parallel Advisors, LLC$14.3K1,3000.00%6qHELD
Rialto Wealth Management, LLC$11.2K1,0210.00%newNEW
GF FUND MANAGEMENT CO. LTD.$10.7K9750.00%7q-6.9%
Steward Partners Investment Advisory, LLC$1.1K1000.00%19qHELD
Rockefeller Capital Management L.P.$494450.00%4qHELD
Caitong International Asset Management Co., Ltd$450410.00%2q+1266.7%
HRT FINANCIAL LP$33730,7480.00%2q+156.4%
SBI Securities Co., Ltd.$307280.00%7qHELD
Virtu Financial LLC$28225,6410.01%newNEW
SG Americas Securities, LLC$13212,0560.00%11q-95.8%-$3.0K
ACADIAN ASSET MANAGEMENT LLC$12911,8360.00%2q+145.7%
ROYAL BANK OF CANADA$0260.00%newNEW

Five percent filings

Anyone crossing 5% of a company must say so within days - far sooner than the next quarterly holdings report. A 13D declares an intent to influence the company; a 13G is the passive version. See all activist filings →

FiledFormFiler % of class
2026-08-1313G/ARaymond Debbane INDIVIDUALwith 7 co-filers7.0%

Quarter by quarter

Coverage begins with the quarter ending 2018-12-31. Earlier filings exist only as occasional late amendments, too sparse to describe a market, so they are not shown.

QuarterHoldersValue SharesNewAdded TrimmedOptions
Q2 202669$260.0M23,503,8242019172.9%
Q1 202652$100.8M19,608,419323110.3%
Q4 202556$105.9M18,006,5451314150.3%
Q3 202550$94.7M19,377,964414110.0%
Q2 202553$106.3M19,442,88999180.1%
Q1 202555$59.8M21,615,123516210.0%
Q4 202462$165.8M24,462,7151224110.0%
Q3 202465$469.4M26,890,7491124150.0%
Q2 202467$520.0M28,170,2291121190.0%
Q1 202460$587.9M27,719,142311590.0%
Q4 202330$292.3M17,567,1734760.0%
Q3 202326$163.0M17,219,1653370.0%
Q2 202328$92.4M17,529,83721150.0%
Q1 202327$107.0M17,873,3303760.0%
Q4 202223$269.3M18,216,8972530.0%
Q3 202229$189.8M19,298,5057950.0%
Q2 202225$124.0M11,008,8054560.0%
Q1 202225$230.8M12,844,9776350.0%
Q4 202121$246.6M10,341,28512600.0%
Q3 20217$39.4M1,955,7991220.0%
Q2 20216$56.4M2,261,4330030.0%
Q1 20216$55.9M2,547,0364200.0%
Q4 20203$10.2M542,0931000.0%
Q3 20202$8.1M542,0002000.0%