DISC MEDICINE INC (IRON)
Institutional ownership reported to the SEC as of Q2 2026, across 15 quarters.
212
Reporting holders
$3.1B
Reported value
109.7%
Of shares outstanding
1.0%
Held as options
+14
Holder change
Institutions report 42,112,054 shares against 38,392,844 outstanding. Shares only - option lines are excluded, which is why this can be compared with the company at all. The count comes from the cover page of the company's own most recent report, so it is dated when that was filed rather than at quarter end. Over 100% because an adviser and a sub-adviser can both report the same shares, and both are counted.
Options share is the part of reported value carried in derivative lines rather than shares. A high figure means institutions are expressing a view on this security without owning much of it.
Holders
| Filer | Value | Shares | Their book | Held | Change |
|---|---|---|---|---|---|
| FMR LLC | $358.0M | 4,894,473 | 0.02% | 15q | -12.4%-$50.6M |
| BlackRock, Inc. | $180.5M | 2,467,899 | 0.00% | 8q | +8.5%+$14.2M |
| RA CAPITAL MANAGEMENT, L.P. | $179.2M | 2,450,221 | 1.56% | 6q | HELD |
| JPMORGAN CHASE & CO | $139.9M | 1,875,795 | 0.01% | 13q | +36.8%+$37.6M |
| WELLINGTON MANAGEMENT GROUP LLP | $127.4M | 1,741,351 | 0.02% | 13q | HELD |
| STATE STREET CORP | $120.6M | 1,648,836 | 0.00% | 15q | -2.9%-$3.6M |
| Vestal Point Capital, LP | $113.4M | 1,550,000 | 2.65% | 5q | +121.4%+$62.2M |
| Atlas Venture Life Science Advisors, LLC | $110.7M | 1,513,875 | 12.56% | 15q | HELD |
| VANGUARD CAPITAL MANAGEMENT LLC | $100.1M | 1,369,027 | 0.00% | 2q | HELD |
| Frazier Life Sciences Management, L.P. | $99.1M | 1,354,852 | 2.16% | 13q | HELD |
| TCG Crossover Management, LLC | $98.1M | 1,341,862 | 2.36% | 2q | HELD |
| Palo Alto Investors LP | $91.4M | 1,249,938 | 4.21% | 5q | +211.1%+$62.0M |
| BVF INC/IL | $84.4M | 1,153,612 | 2.16% | 3q | -9.3%-$8.7M |
| Woodline Partners LP | $70.1M | 958,281 | 0.22% | 9q | HELD |
| Siren, L.L.C. | $65.0M | 888,401 | 1.31% | 6q | -10.1%-$7.3M |
| Logos Global Management LP | $64.0M | 875,000 | 2.76% | 9q | +56.2%+$23.0M |
| Opaleye Management Inc. | $62.5M | 855,000 | 5.66% | 6q | +103.1%+$31.7M |
| GEODE CAPITAL MANAGEMENT, LLC | $57.8M | 789,724 | 0.00% | 15q | +6.1%+$3.3M |
| Assenagon Asset Management S.A. | $56.2M | 768,316 | 0.04% | 4q | +40.7%+$16.2M |
| DEERFIELD MANAGEMENT COMPANY, L.P. | $48.1M | 657,000 | 0.50% | 13q | HELD |
| DIMENSIONAL FUND ADVISORS LP | $41.6M | 569,018 | 0.01% | 8q | +44.3%+$12.8M |
| Bellevue Group AG | $41.0M | 560,000 | 0.86% | 2q | +21.9%+$7.4M |
| Saturn V Capital Management LP | $38.4M | 524,730 | 5.50% | 11q | +16.6%+$5.5M |
| ARMISTICE CAPITAL, LLC | $33.6M | 460,000 | 0.41% | 8q | -14.2%-$5.6M |
| JENNISON ASSOCIATES LLC | $32.1M | 439,520 | 0.02% | 3q | -28.0%-$12.5M |
| Aberdeen Group plc | $32.0M | 438,174 | 0.04% | 5q | +16.7%+$4.6M |
| EVENTIDE ASSET MANAGEMENT, LLC | $28.9M | 395,651 | 0.39% | 6q | HELD |
| Pictet Asset Management Holding SA | $28.2M | 385,375 | 0.03% | 4q | HELD |
| LOOMIS SAYLES & CO L P | $27.9M | 381,864 | 0.04% | 3q | +20.4%+$4.7M |
| Foresite Capital Management V, LLC | $27.4M | 374,069 | 7.55% | 15q | HELD |
| ORBIMED ADVISORS LLC | $26.2M | 357,535 | 0.48% | 15q | -66.5%-$51.9M |
| BAKER BROS. ADVISORS LP | $25.6M | 349,657 | 0.13% | 7q | HELD |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $20.6M | 281,937 | 0.00% | 2q | +14.0%+$2.5M |
| Octagon Capital Advisors LP | $19.7M | 270,000 | 1.78% | 2q | HELD |
| NORTHERN TRUST CORP | $19.4M | 264,990 | 0.00% | 13q | +7.2%+$1.3M |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $18.8M | 257,382 | 0.00% | 13q | +2.5%+$452.5K |
| Sixth Street Partners Management Company, L.P. | $18.8M | 257,382 | 0.00% | new | NEW |
| CITADEL ADVISORS LLC | $17.7M | 209,308 | 0.00% | 15q | +113.7%+$9.4M |
| Checkpoint Capital L.P. | $17.6M | 240,125 | 4.51% | 8q | -16.2%-$3.4M |
| VANGUARD FIDUCIARY TRUST CO | $16.5M | 225,198 | 0.00% | 2q | +3.6%+$567.7K |
| Bank of New York Mellon Corp | $15.0M | 204,727 | 0.00% | 13q | HELD |
| BNP PARIBAS FINANCIAL MARKETS | $13.5M | 184,695 | 0.00% | 7q | +44.6%+$4.2M |
| Catalio Capital Management, LP | $11.7M | 159,384 | 2.19% | 5q | +29.6%+$2.7M |
| Caption Management, LLC | $11.0M | options only | 0.05% | 2q | OPTIONS |
| Sofinnova Investments, Inc. | $10.7M | 146,239 | 0.55% | 10q | +86.7%+$5.0M |
| Bain Capital Life Sciences Investors, LLC | $10.3M | 141,234 | 0.61% | 2q | HELD |
| TWO SIGMA INVESTMENTS, LP | $10.0M | 136,750 | 0.01% | new | NEW |
| BANK OF AMERICA CORP /DE/ | $9.9M | 135,111 | 0.00% | 15q | -19.0%-$2.3M |
| Alyeska Investment Group, L.P. | $9.1M | 125,000 | 0.02% | 3q | HELD |
| Ensign Peak Advisors, Inc | $8.9M | 122,111 | 0.01% | 13q | -68.1%-$19.1M |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | $8.3M | 114,109 | 0.00% | 10q | +2.9%+$235.4K |
| UBS Group AG | $8.1M | 110,971 | 0.00% | 15q | +12.5%+$903.3K |
| Trexquant Investment LP | $7.9M | 107,699 | 0.05% | new | NEW |
| KENNEDY CAPITAL MANAGEMENT LLC | $7.8M | 106,769 | 0.14% | 4q | -1.4%-$111.0K |
| MILLENNIUM MANAGEMENT LLC | $7.8M | 106,248 | 0.00% | 7q | +27.6%+$1.7M |
| GOLDMAN SACHS GROUP INC | $7.1M | 97,383 | 0.00% | 12q | -84.8%-$39.7M |
| MORGAN STANLEY | $6.7M | 91,595 | 0.00% | 15q | -2.8%-$195.2K |
| SILVERARC CAPITAL MANAGEMENT, LLC | $6.1M | 82,800 | 0.63% | 2q | -57.8%-$8.3M |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $6.0M | 2,914 | 0.00% | 11q | -81.1%-$25.6M |
| RAYMOND JAMES FINANCIAL INC | $5.7M | 77,980 | 0.00% | 7q | +74.5%+$2.4M |
| Squarepoint Ops LLC | $5.5M | 75,872 | 0.01% | 4q | +139.3%+$3.2M |
| DNB Asset Management AS | $5.3M | 73,127 | 0.01% | 5q | -24.4%-$1.7M |
| Casdin Capital, LLC | $4.8M | 65,000 | 0.24% | 2q | HELD |
| SPHERA FUNDS MANAGEMENT LTD. | $4.6M | 63,538 | 0.61% | 2q | +18.7%+$731.4K |
| Nuveen, LLC | $4.4M | 60,357 | 0.00% | 6q | +17.5%+$656.6K |
| PEAK6 LLC | $4.4M | options only | 0.01% | new | OPTIONS |
| KVP Capital Advisors, LP | $4.3M | 58,250 | 3.13% | 3q | HELD |
| MOORE CAPITAL MANAGEMENT, LP | $4.2M | 57,796 | 0.06% | 2q | HELD |
| XTX Topco Ltd | $4.1M | 56,710 | 0.05% | 3q | +64.8%+$1.6M |
| NEXTBio Capital Management LP | $3.9M | 52,655 | 1.77% | 3q | HELD |
| ALGERT GLOBAL LLC | $3.8M | 51,850 | 0.04% | 2q | +14.3%+$474.7K |
| ExodusPoint Capital Management, LP | $3.8M | 51,623 | 0.02% | new | NEW |
| SCHRODER INVESTMENT MANAGEMENT GROUP | $3.7M | 50,000 | 0.00% | 11q | -1.9%-$71.4K |
| Burkehill Global Management, LP | $3.7M | 50,000 | 0.13% | 3q | HELD |
| Brevan Howard Capital Management LP | $3.7M | 49,996 | 0.03% | 3q | +54.3%+$1.3M |
| Swiss National Bank | $3.6M | 49,800 | 0.00% | 12q | +3.8%+$131.7K |
| AMERIPRISE FINANCIAL INC | $3.4M | 45,874 | 0.00% | 7q | -50.0%-$3.3M |
| Atle Fund Management AB | $3.2M | 43,682 | 0.86% | 5q | -59.3%-$4.6M |
| Quadrature Capital Ltd | $3.1M | 42,419 | 0.03% | new | NEW |
| Invesco Ltd. | $3.1M | 42,057 | 0.00% | 13q | +37.3%+$835.2K |
| ALPS ADVISORS INC | $2.8M | 38,565 | 0.01% | 13q | +24.2%+$549.1K |
| CITIGROUP INC | $2.8M | 38,317 | 0.00% | 15q | +394.9%+$2.2M |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | $2.8M | 38,262 | 0.00% | 5q | -4.1%-$120.5K |
| Universal- Beteiligungs- und Servicegesellschaft mbH | $2.7M | 36,634 | 0.00% | 6q | -3.6%-$100.3K |
| RHUMBLINE ADVISERS | $2.6M | 35,844 | 0.00% | 13q | +8.4%+$203.8K |
| LAZARD ASSET MANAGEMENT LLC | $2.6M | 35,034 | 0.00% | 3q | -11.1%-$319.3K |
| SEVEN GRAND MANAGERS, LLC | $2.6M | 35,000 | 0.10% | 3q | HELD |
| MARSHALL WACE, LLP | $2.5M | 34,394 | 0.00% | new | NEW |
| Jump Financial, LLC | $2.4M | 32,549 | 0.02% | 2q | -60.2%-$3.6M |
| JANE STREET GROUP, LLC | $2.4M | 16,011 | 0.00% | 4q | HELD |
| BANK OF MONTREAL /CAN/ | $2.4M | 32,308 | 0.00% | 6q | +12.3%+$258.5K |
| DEUTSCHE BANK AG\ | $2.2M | 30,643 | 0.00% | 13q | +25.6%+$456.5K |
| ALLIANCEBERNSTEIN L.P. | $2.2M | 34,670 | 0.00% | 13q | +41.3%+$647.7K |
| RTW INVESTMENTS, LP | $2.2M | 30,000 | 0.02% | 3q | HELD |
| Squadron Capital Management LLC | $2.2M | options only | 0.68% | new | OPTIONS |
| VICTORY CAPITAL MANAGEMENT INC | $2.1M | 29,117 | 0.00% | 12q | HELD |
| WELLS FARGO & COMPANY/MN | $2.1M | 28,924 | 0.00% | 14q | -1.6%-$33.4K |
| TUDOR INVESTMENT CORP ET AL | $2.1M | 28,663 | 0.00% | 3q | -7.5%-$171.1K |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | $2.0M | 27,771 | 0.00% | 13q | -14.5%-$345.4K |
| Y-Intercept (Hong Kong) Ltd | $2.0M | 26,888 | 0.04% | new | NEW |
Five percent filings
Anyone crossing 5% of a company must say so within days - far sooner than the next quarterly holdings report. A 13D declares an intent to influence the company; a 13G is the passive version. See all activist filings →
| Filed | Form | Filer | % of class |
|---|---|---|---|
| 2026-08-06 | 13G/A | FMR LLCwith 1 co-filers | 12.8% |
Quarter by quarter
Coverage begins with the quarter ending 2018-12-31. Earlier filings exist only as occasional late amendments, too sparse to describe a market, so they are not shown.
| Quarter | Holders | Value | Shares | New | Added | Trimmed | Options |
|---|---|---|---|---|---|---|---|
| Q2 2026 | 212 | $3.1B | 42,112,054 | 37 | 70 | 58 | 1.0% |
| Q1 2026 | 198 | $2.6B | 40,523,492 | 41 | 75 | 39 | 1.1% |
| Q4 2025 | 185 | $2.9B | 36,620,213 | 36 | 78 | 48 | 0.4% |
| Q3 2025 | 160 | $2.2B | 33,733,670 | 25 | 55 | 40 | 0.2% |
| Q2 2025 | 142 | $1.7B | 32,471,551 | 23 | 63 | 35 | 1.4% |
| Q1 2025 | 149 | $1.6B | 31,771,756 | 26 | 70 | 26 | 0.1% |
| Q4 2024 | 142 | $1.6B | 25,151,616 | 29 | 43 | 42 | 0.4% |
| Q3 2024 | 120 | $1.3B | 26,236,158 | 19 | 51 | 26 | 0.1% |
| Q2 2024 | 114 | $1.2B | 27,524,245 | 25 | 51 | 26 | 0.2% |
| Q1 2024 | 127 | $1.4B | 21,447,008 | 32 | 53 | 26 | 6.2% |
| Q4 2023 | 105 | $1.2B | 19,644,281 | 25 | 35 | 28 | 2.1% |
| Q3 2023 | 88 | $922.1M | 19,337,300 | 18 | 37 | 16 | 1.5% |
| Q2 2023 | 85 | $2.7B | 18,651,406 | 56 | 17 | 9 | 69.6% |
| Q1 2023 | 39 | $265.6M | 12,534,843 | 11 | 12 | 6 | 0.0% |
| Q4 2022 | 25 | $211.4M | 10,535,966 | 24 | 0 | 0 | 1.0% |