VERTEX PHARMACEUTICALS INC (VRTX)
Institutional ownership reported to the SEC as of Q2 2026, across 31 quarters.
1,671
Reporting holders
$120.0B
Reported value
94.1%
Of shares outstanding
1.4%
Held as options
+60
Holder change
Institutions report 238,567,822 shares against 253,460,924 outstanding. Shares only - option lines are excluded, which is why this can be compared with the company at all. The count comes from the cover page of the company's own most recent report, so it is dated when that was filed rather than at quarter end. A figure this high can overstate: where an adviser and a sub-adviser both report the same shares, both are counted.
Options share is the part of reported value carried in derivative lines rather than shares. A high figure means institutions are expressing a view on this security without owning much of it.
Holders
| Filer | Value | Shares | Their book | Held | Change |
|---|---|---|---|---|---|
| Capital World Investors | $13.0B | 26,115,014 | 1.53% | 31q | +2.9%+$371.0M |
| BlackRock, Inc. | $12.0B | 24,109,373 | 0.18% | 8q | +0.6%+$69.5M |
| Capital Research Global Investors | $9.7B | 19,490,637 | 1.35% | 14q | -7.7%-$812.3M |
| VANGUARD CAPITAL MANAGEMENT LLC | $8.2B | 16,580,713 | 0.18% | 2q | HELD |
| STATE STREET CORP | $5.9B | 11,871,459 | 0.17% | 31q | +1.2%+$70.2M |
| Invesco Ltd. | $4.0B | 8,043,052 | 0.32% | 31q | +1.9%+$74.7M |
| JPMORGAN CHASE & CO | $3.3B | 6,517,600 | 0.18% | 31q | -7.3%-$263.8M |
| GEODE CAPITAL MANAGEMENT, LLC | $3.0B | 6,017,848 | 0.16% | 31q | -2.0%-$60.2M |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $2.4B | 4,878,987 | 0.11% | 2q | -5.2%-$132.4M |
| Capital International Investors | $2.3B | 4,695,144 | 0.48% | 7q | -8.4%-$214.1M |
| LOOMIS SAYLES & CO L P | $1.9B | 3,920,953 | 2.44% | 27q | -2.1%-$41.2M |
| FRANKLIN RESOURCES INC | $1.7B | 3,347,253 | 0.36% | 31q | +507.3%+$1.4B |
| WELLINGTON MANAGEMENT GROUP LLP | $1.6B | 3,247,658 | 0.28% | 31q | +1.1%+$17.4M |
| MORGAN STANLEY | $1.6B | 3,242,139 | 0.09% | 35q | +1.7%+$26.5M |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | $1.5B | 3,086,683 | 0.28% | 31q | +1.0%+$14.5M |
| BANK OF AMERICA CORP /DE/ | $1.5B | 3,039,178 | 0.10% | 31q | +5.6%+$80.0M |
| JENNISON ASSOCIATES LLC | $1.5B | 2,998,530 | 0.89% | 31q | +9.4%+$128.4M |
| NORGES BANK | $1.5B | 2,971,681 | 0.15% | 32q | -6.5%-$101.8M |
| ALLIANCEBERNSTEIN L.P. | $1.3B | 3,019,315 | 0.45% | 31q | -22.8%-$398.1M |
| AMERIPRISE FINANCIAL INC | $1.3B | 2,604,822 | 0.26% | 31q | -50.5%-$1.3B |
| GOLDMAN SACHS GROUP INC | $1.3B | 2,481,761 | 0.11% | 31q | +2.6%+$32.4M |
| NORTHERN TRUST CORP | $1.2B | 2,486,478 | 0.14% | 31q | -3.0%-$38.6M |
| Clearbridge Investments, LLC | $1.2B | 2,342,915 | 0.96% | 31q | -13.3%-$177.9M |
| VICTORY CAPITAL MANAGEMENT INC | $1.1B | 2,173,152 | 0.61% | 31q | +15.1%+$141.4M |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $1.0B | 2,041,282 | 0.13% | 31q | +6.3%+$59.8M |
| Sixth Street Partners Management Company, L.P. | $1.0B | 2,041,282 | 0.13% | new | NEW |
| Legal & General Group Plc | $928.9M | 1,870,015 | 0.19% | 31q | -4.4%-$42.6M |
| Bank of New York Mellon Corp | $830.8M | 1,672,623 | 0.14% | 31q | +5.4%+$42.8M |
| DEUTSCHE BANK AG\ | $784.4M | 1,579,110 | 0.23% | 34q | +2.7%+$20.6M |
| Amundi | $768.2M | 1,546,509 | 0.19% | 21q | +5.0%+$36.8M |
| Assenagon Asset Management S.A. | $754.6M | 1,519,128 | 0.47% | 31q | +182.8%+$487.7M |
| FMR LLC | $723.8M | 1,457,158 | 0.03% | 31q | -27.9%-$279.7M |
| VANGUARD FIDUCIARY TRUST CO | $708.0M | 1,425,390 | 0.16% | 2q | -2.8%-$20.0M |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $662.5M | 144,174 | 0.05% | 31q | +613.0%+$569.6M |
| Jupiter Topco LLC | $625.8M | 1,259,997 | 0.26% | new | FIRST |
| DIMENSIONAL FUND ADVISORS LP | $580.7M | 1,168,956 | 0.11% | 31q | +18.2%+$89.2M |
| WCM INVESTMENT MANAGEMENT, LLC | $575.6M | 1,152,094 | 1.04% | 7q | +2.7%+$15.4M |
| Nuveen, LLC | $537.3M | 1,081,685 | 0.13% | 6q | HELD |
| ROYAL BANK OF CANADA | $486.9M | 980,259 | 0.07% | 31q | -11.8%-$65.4M |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | $446.0M | 897,893 | 0.45% | 31q | +5.9%+$24.8M |
| CITADEL ADVISORS LLC | $441.9M | 510,430 | 0.05% | 31q | +50.4%+$148.2M |
| UBS Group AG | $399.1M | 712,259 | 0.05% | 31q | +12.9%+$45.7M |
| WELLS FARGO & COMPANY/MN | $372.3M | 749,528 | 0.06% | 31q | -49.7%-$367.8M |
| ARROWSTREET CAPITAL, LIMITED PARTNERSHIP | $366.8M | 738,378 | 0.16% | 5q | +15.6%+$49.4M |
| BARCLAYS PLC | $364.2M | 733,274 | 0.07% | 31q | +10.6%+$34.8M |
| CITIGROUP INC | $361.3M | 706,968 | 0.12% | 31q | +3.5%+$12.3M |
| Swiss National Bank | $356.4M | 717,440 | 0.19% | 31q | -3.6%-$13.5M |
| HSBC HOLDINGS PLC | $335.8M | 676,247 | 0.14% | 31q | +3.2%+$10.3M |
| Mitsubishi UFJ Asset Management Co., Ltd. | $321.5M | 647,193 | 0.18% | 31q | +8.3%+$24.7M |
| Hudson Bay Capital Management LP | $318.1M | 390,440 | 0.86% | 9q | +767.6%+$281.5M |
| AQR CAPITAL MANAGEMENT LLC | $305.0M | 616,170 | 0.11% | 31q | +260.3%+$220.3M |
| Sumitomo Mitsui Trust Group, Inc. | $304.0M | 611,907 | 0.17% | 31q | HELD |
| AMERICAN CENTURY COMPANIES INC | $288.6M | 580,901 | 0.13% | 31q | -28.6%-$115.4M |
| Bellevue Group AG | $287.4M | 578,634 | 6.05% | 31q | -15.1%-$51.3M |
| MILLENNIUM MANAGEMENT LLC | $280.1M | 468,410 | 0.10% | 31q | +1419.7%+$261.6M |
| NEUBERGER BERMAN GROUP LLC | $277.9M | 559,445 | 0.18% | 31q | +1.4%+$3.9M |
| RAYMOND JAMES FINANCIAL INC | $276.6M | 556,876 | 0.07% | 7q | +25.3%+$55.8M |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | $275.2M | 554,085 | 0.21% | 31q | HELD |
| Vanguard Global Advisers, LLC | $271.9M | 547,463 | 0.13% | 2q | -1.5%-$4.1M |
| MARSHALL WACE, LLP | $270.7M | 543,897 | 0.21% | 17q | +71.5%+$112.9M |
| Pictet Asset Management Holding SA | $268.3M | 539,255 | 0.26% | 12q | +59.7%+$100.4M |
| National Pension Service | $268.0M | 539,530 | 0.17% | 31q | +1.4%+$3.7M |
| EDGEWOOD MANAGEMENT LLC | $263.8M | 531,003 | 2.72% | 31q | -41.3%-$185.8M |
| Life Cycle Investment Partners Ltd | $255.4M | 514,179 | 1.19% | 3q | +16.8%+$36.6M |
| VOYA INVESTMENT MANAGEMENT LLC | $250.4M | 505,219 | 0.22% | 31q | -4.1%-$10.8M |
| VANGUARD ASSET MANAGEMENT, Ltd | $245.5M | 494,186 | 0.17% | 2q | +11.8%+$25.8M |
| ENVESTNET ASSET MANAGEMENT INC | $242.2M | 487,627 | 0.06% | 31q | -3.2%-$7.9M |
| California Public Employees Retirement System | $222.3M | 447,499 | 0.13% | 31q | -11.1%-$27.8M |
| MASSACHUSETTS FINANCIAL SERVICES CO /MA/ | $214.6M | 423,049 | 0.07% | 31q | +29.2%+$48.5M |
| BANK OF MONTREAL /CAN/ | $212.3M | 427,448 | 0.07% | 31q | +9.5%+$18.4M |
| Chevy Chase Trust Holdings, LLC | $201.8M | 406,303 | 0.52% | 31q | HELD |
| Robeco Institutional Asset Management B.V. | $200.9M | 404,396 | 0.25% | 38q | +0.7%+$1.4M |
| RHUMBLINE ADVISERS | $196.9M | 396,380 | 0.15% | 31q | -6.3%-$13.3M |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | $195.7M | 393,964 | 0.27% | 31q | +56.3%+$70.5M |
| PRINCIPAL FINANCIAL GROUP INC | $193.5M | 389,511 | 0.10% | 31q | -8.7%-$18.4M |
| Zurcher Kantonalbank (Zurich Cantonalbank) | $189.1M | 380,762 | 0.36% | 31q | +1.0%+$1.9M |
| DZ BANK AG Deutsche Zentral Genossenschafts Bank, Frankfurt am Main | $178.5M | 359,332 | 0.14% | 32q | -1.4%-$2.6M |
| CANADA PENSION PLAN INVESTMENT BOARD | $176.4M | 355,082 | 0.10% | 31q | +86.8%+$82.0M |
| Russell Investments Group, Ltd. | $167.5M | 336,990 | 0.15% | 31q | -8.3%-$15.3M |
| Universal- Beteiligungs- und Servicegesellschaft mbH | $160.7M | 323,752 | 0.25% | 7q | -4.3%-$7.2M |
| RENAISSANCE TECHNOLOGIES LLC | $159.0M | 320,008 | 0.22% | 31q | -24.1%-$50.5M |
| Bank Julius Baer & Co. Ltd, Zurich | $158.9M | 319,371 | 0.41% | 26q | +0.6%+$977.8K |
| AMF Tjanstepension AB | $156.4M | 314,765 | 0.93% | 9q | +0.6%+$918.0K |
| JANE STREET GROUP, LLC | $155.2M | 11,231 | 0.01% | 31q | -90.9%-$1.5B |
| BNP PARIBAS FINANCIAL MARKETS | $144.4M | 262,258 | 0.05% | 31q | -36.9%-$84.5M |
| FIRST TRUST ADVISORS LP | $143.6M | 289,179 | 0.08% | 31q | -5.6%-$8.6M |
| LPL Financial LLC | $143.6M | 289,111 | 0.03% | 31q | +7.9%+$10.5M |
| ProShare Advisors LLC | $143.0M | 287,847 | 0.21% | 31q | -22.9%-$42.6M |
| TWO SIGMA INVESTMENTS, LP | $142.8M | 285,000 | 0.10% | 3q | -24.6%-$46.7M |
| Swedbank AB | $140.3M | 282,444 | 0.12% | 21q | +4.0%+$5.4M |
| NEW YORK STATE COMMON RETIREMENT FUND | $137.9M | 277,614 | 0.17% | 31q | -5.1%-$7.4M |
| NATIONAL BANK OF CANADA /FI/ | $137.8M | 172,898 | 0.10% | 19q | -36.5%-$79.1M |
| BAILLIE GIFFORD & CO | $135.4M | 272,561 | 0.12% | 9q | +36.7%+$36.3M |
| Cerity Partners LLC | $127.1M | 255,874 | 0.15% | 31q | -13.7%-$20.3M |
| Nykredit A/S | $123.2M | 248,068 | 0.39% | new | FIRST |
| ROYAL LONDON ASSET MANAGEMENT LTD | $119.9M | 241,280 | 0.22% | 32q | -4.3%-$5.4M |
| B. Metzler seel. Sohn & Co. AG | $114.9M | 231,381 | 0.99% | 19q | -54.7%-$138.9M |
| Corient Private Wealth LP | $112.0M | 225,398 | 0.07% | 15q | +160.6%+$69.0M |
| AVIVA PLC | $111.1M | 223,593 | 0.16% | 31q | +0.5%+$566.8K |
| ING GROEP NV | $110.8M | 223,124 | 0.54% | 4q | +241.0%+$78.3M |
Showing the largest 100 of 1,760 reported holders.
Quarter by quarter
Coverage begins with the quarter ending 2018-12-31. Earlier filings exist only as occasional late amendments, too sparse to describe a market, so they are not shown.
| Quarter | Holders | Value | Shares | New | Added | Trimmed | Options |
|---|---|---|---|---|---|---|---|
| Q2 2026 | 1,671 | $120.0B | 238,567,822 | 166 | 650 | 541 | 1.4% |
| Q1 2026 | 1,611 | $106.9B | 235,998,259 | 120 | 602 | 545 | 1.4% |
| Q4 2025 | 1,590 | $108.5B | 236,016,118 | 166 | 555 | 498 | 1.4% |
| Q3 2025 | 1,436 | $92.1B | 231,785,798 | 120 | 500 | 537 | 1.6% |
| Q2 2025 | 1,476 | $105.8B | 234,290,750 | 96 | 534 | 536 | 1.4% |
| Q1 2025 | 1,513 | $112.4B | 229,019,809 | 176 | 564 | 502 | 1.2% |
| Q4 2024 | 1,458 | $92.5B | 226,099,659 | 96 | 487 | 526 | 1.5% |
| Q3 2024 | 1,439 | $109.4B | 231,868,570 | 100 | 544 | 491 | 1.5% |
| Q2 2024 | 1,427 | $109.5B | 230,398,397 | 139 | 575 | 446 | 1.4% |
| Q1 2024 | 1,356 | $97.9B | 230,926,493 | 145 | 527 | 419 | 1.5% |
| Q4 2023 | 1,311 | $94.3B | 227,170,383 | 140 | 481 | 398 | 1.9% |
| Q3 2023 | 1,142 | $76.8B | 216,964,223 | 72 | 437 | 361 | 1.6% |
| Q2 2023 | 1,115 | $77.4B | 217,853,859 | 106 | 398 | 390 | 1.1% |
| Q1 2023 | 1,032 | $74.1B | 234,298,214 | 88 | 367 | 371 | 0.9% |
| Q4 2022 | 958 | $58.5B | 200,632,613 | 103 | 325 | 320 | 1.2% |
| Q3 2022 | 1,131 | $69.9B | 238,121,401 | 107 | 409 | 385 | 1.3% |
| Q2 2022 | 1,113 | $67.0B | 234,512,936 | 125 | 341 | 426 | 1.4% |
| Q1 2022 | 1,077 | $62.5B | 234,270,943 | 148 | 393 | 364 | 2.3% |
| Q4 2021 | 1,033 | $52.1B | 230,535,615 | 140 | 332 | 350 | 2.9% |
| Q3 2021 | 935 | $42.9B | 230,900,578 | 89 | 333 | 335 | 2.4% |
| Q2 2021 | 978 | $48.3B | 232,691,588 | 107 | 383 | 320 | 3.0% |
| Q1 2021 | 998 | $52.1B | 236,202,473 | 135 | 410 | 294 | 2.6% |
| Q4 2020 | 970 | $58.0B | 240,325,954 | 113 | 374 | 303 | 1.3% |
| Q3 2020 | 949 | $66.6B | 242,791,277 | 81 | 380 | 306 | 0.8% |
| Q2 2020 | 966 | $71.5B | 244,260,789 | 161 | 391 | 266 | 0.9% |
| Q1 2020 | 863 | $59.6B | 248,231,294 | 130 | 318 | 268 | 1.0% |
| Q4 2019 | 816 | $55.1B | 248,092,218 | 113 | 254 | 253 | 1.4% |
| Q3 2019 | 713 | $42.6B | 248,418,992 | 59 | 268 | 226 | 1.3% |
| Q2 2019 | 721 | $46.1B | 247,452,048 | 66 | 262 | 233 | 1.7% |
| Q1 2019 | 746 | $45.9B | 246,853,826 | 83 | 278 | 215 | 1.2% |
| Q4 2018 | 714 | $41.8B | 247,159,031 | 9 | 12 | 13 | 2.0% |