TAYSHA GENE THERAPIES INC (TSHA)
Institutional ownership reported to the SEC as of Q2 2026, across 24 quarters.
202
Reporting holders
$2.1B
Reported value
93.3%
Of shares outstanding
0.3%
Held as options
+13
Holder change
Institutions report 303,886,741 shares against 325,833,545 outstanding. Shares only - option lines are excluded, which is why this can be compared with the company at all. The count comes from the cover page of the company's own most recent report, so it is dated when that was filed rather than at quarter end. A figure this high can overstate: where an adviser and a sub-adviser both report the same shares, both are counted.
Options share is the part of reported value carried in derivative lines rather than shares. A high figure means institutions are expressing a view on this security without owning much of it.
Holders
| Filer | Value | Shares | Their book | Held | Change |
|---|---|---|---|---|---|
| Avoro Capital Advisors LLC | $162.7M | 23,888,888 | 1.46% | 12q | +10.1%+$14.9M |
| RA CAPITAL MANAGEMENT, L.P. | $160.4M | 23,555,648 | 1.39% | 12q | HELD |
| GOLDMAN SACHS GROUP INC | $154.7M | 22,713,118 | 0.01% | 11q | +1.5%+$2.3M |
| BlackRock, Inc. | $140.9M | 20,691,927 | 0.00% | 8q | +12.7%+$15.8M |
| Vestal Point Capital, LP | $132.2M | 19,415,000 | 3.09% | 5q | +7.9%+$9.6M |
| MORGAN STANLEY | $112.3M | 16,487,479 | 0.01% | 23q | -8.2%-$10.1M |
| RTW INVESTMENTS, LP | $92.3M | 13,560,258 | 0.79% | 12q | -0.9%-$817.1K |
| FMR LLC | $90.8M | 13,336,413 | 0.00% | 24q | -6.9%-$6.7M |
| VANGUARD CAPITAL MANAGEMENT LLC | $85.0M | 12,478,595 | 0.00% | 2q | +22.0%+$15.3M |
| STATE STREET CORP | $77.8M | 11,421,920 | 0.00% | 23q | +1.9%+$1.4M |
| Siren, L.L.C. | $67.1M | 9,846,579 | 1.36% | 8q | +11.5%+$6.9M |
| Octagon Capital Advisors LP | $66.0M | 9,693,244 | 5.93% | 10q | +9.4%+$5.7M |
| GEODE CAPITAL MANAGEMENT, LLC | $44.7M | 6,560,394 | 0.00% | 23q | +18.6%+$7.0M |
| Polar Capital Holdings Plc | $34.8M | 5,117,133 | 0.08% | 12q | -9.5%-$3.7M |
| MPM BIOIMPACT LLC | $30.6M | 4,500,000 | 1.87% | new | NEW |
| D. E. Shaw & Co., Inc. | $30.0M | 4,398,652 | 0.01% | 5q | -0.6%-$195.1K |
| Palo Alto Investors LP | $28.4M | 4,174,146 | 1.31% | 11q | +200.0%+$19.0M |
| BAKER BROS. ADVISORS LP | $27.3M | 4,004,756 | 0.14% | 12q | HELD |
| WELLINGTON MANAGEMENT GROUP LLP | $27.1M | 3,975,605 | 0.00% | 8q | +534.7%+$22.8M |
| HEALTHCARE OF ONTARIO PENSION PLAN TRUST FUND | $26.5M | 3,885,501 | 0.04% | 3q | +34.8%+$6.8M |
| GordonMD Global Investments LP | $24.5M | 723,185 | 11.86% | 3q | -1.9%-$486.7K |
| Casdin Capital, LLC | $22.1M | 3,250,000 | 1.11% | 3q | HELD |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $21.4M | 3,140,009 | 0.00% | 2q | +55.3%+$7.6M |
| ADAR1 Capital Management, LLC | $20.7M | 3,040,466 | 0.95% | 11q | +2.0%+$415.7K |
| Pictet Asset Management Holding SA | $18.9M | 2,770,701 | 0.02% | 3q | +14242.6%+$18.7M |
| Aberdeen Group plc | $15.8M | 2,327,152 | 0.02% | 3q | +127.9%+$8.9M |
| FARALLON CAPITAL MANAGEMENT, L.L.C. | $15.3M | 2,250,000 | 0.07% | new | NEW |
| NORGES BANK | $15.2M | 2,233,600 | 0.00% | 2q | +21.5%+$2.7M |
| NORTHERN TRUST CORP | $15.2M | 2,226,210 | 0.00% | 23q | +22.7%+$2.8M |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $15.0M | 2,200,695 | 0.00% | 23q | +21.7%+$2.7M |
| Sixth Street Partners Management Company, L.P. | $15.0M | 2,200,695 | 0.00% | new | NEW |
| MILLENNIUM MANAGEMENT LLC | $14.5M | 2,126,838 | 0.01% | 7q | -35.2%-$7.9M |
| ORBIMED ADVISORS LLC | $13.6M | 2,000,000 | 0.25% | new | NEW |
| RICE HALL JAMES & ASSOCIATES, LLC | $13.6M | 1,992,229 | 0.66% | 4q | +2.4%+$323.9K |
| VANGUARD FIDUCIARY TRUST CO | $12.9M | 1,896,474 | 0.00% | 2q | +23.9%+$2.5M |
| B Group, Inc. | $12.3M | 1,800,556 | 5.76% | 7q | HELD |
| Affinity Asset Advisors, LLC | $11.9M | 1,750,000 | 0.54% | 5q | +75.0%+$5.1M |
| CITADEL ADVISORS LLC | $11.7M | 1,535,287 | 0.00% | 19q | +273.4%+$8.5M |
| BARCLAYS PLC | $11.1M | 1,630,659 | 0.00% | 9q | -42.0%-$8.0M |
| HEIGHTS CAPITAL MANAGEMENT, INC | $10.2M | 1,500,000 | 2.36% | new | NEW |
| Seven Fleet Capital Management LP | $9.9M | 1,504,400 | 1.64% | 3q | +140.4%+$5.8M |
| BANK OF AMERICA CORP /DE/ | $9.3M | 1,372,845 | 0.00% | 23q | -18.1%-$2.1M |
| Granahan Investment Management, LLC | $8.9M | 1,305,177 | 0.32% | 9q | +47.8%+$2.9M |
| Quantum Private Wealth, LLC | $5.5M | 812,027 | 1.42% | 19q | -4.4%-$253.2K |
| FIRST TRUST ADVISORS LP | $5.4M | 791,169 | 0.00% | new | NEW |
| JPMORGAN CHASE & CO | $5.2M | 766,282 | 0.00% | 23q | +1.5%+$77.4K |
| Sands Capital Alternatives, LLC | $4.9M | 724,873 | 0.80% | 20q | HELD |
| Bank of New York Mellon Corp | $4.8M | 697,971 | 0.00% | 9q | +14.8%+$611.9K |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $4.6M | 27,164 | 0.00% | 12q | -76.6%-$15.3M |
| BNP PARIBAS FINANCIAL MARKETS | $4.4M | 640,035 | 0.00% | 7q | +432.5%+$3.5M |
| PANAGORA ASSET MANAGEMENT INC | $4.0M | 590,387 | 0.01% | 3q | +224.1%+$2.8M |
| UBS Group AG | $4.0M | 588,427 | 0.00% | 24q | +13.7%+$481.7K |
| AFFINITY WEALTH MANAGEMENT LLC | $3.9M | 576,808 | 0.51% | new | NEW |
| Squarepoint Ops LLC | $3.9M | 569,269 | 0.00% | 5q | +38.8%+$1.1M |
| ACUTA CAPITAL PARTNERS, LLC | $3.8M | 561,808 | 2.67% | 5q | +27.8%+$833.2K |
| Nuveen, LLC | $3.8M | 555,693 | 0.00% | 6q | +1.2%+$44.5K |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | $3.8M | 553,000 | 0.01% | new | NEW |
| DIADEMA PARTNERS LP | $3.6M | 522,619 | 0.45% | new | NEW |
| Hennion & Walsh Asset Management, Inc. | $3.5M | 519,120 | 0.10% | 3q | +32.6%+$869.3K |
| Woodline Partners LP | $3.5M | 513,828 | 0.01% | 9q | HELD |
| Holocene Advisors, LP | $3.5M | 510,000 | 0.01% | new | NEW |
| Ghisallo Capital Management LLC | $3.4M | 505,000 | 0.07% | new | NEW |
| Burkehill Global Management, LP | $3.4M | 500,000 | 0.12% | new | NEW |
| POLEN CAPITAL MANAGEMENT LLC | $3.3M | 489,219 | 0.03% | 3q | +53.0%+$1.2M |
| DIMENSIONAL FUND ADVISORS LP | $3.2M | 464,771 | 0.00% | 4q | -5.2%-$174.9K |
| VOYA INVESTMENT MANAGEMENT LLC | $2.9M | 425,363 | 0.00% | 9q | -16.9%-$589.9K |
| Trexquant Investment LP | $2.6M | 379,577 | 0.02% | new | NEW |
| Swiss National Bank | $2.5M | 369,000 | 0.00% | 3q | +37.3%+$682.4K |
| MOORE CAPITAL MANAGEMENT, LP | $2.4M | 358,374 | 0.04% | 2q | +9.0%+$201.2K |
| WELLS FARGO & COMPANY/MN | $2.3M | 333,314 | 0.00% | 19q | -9.1%-$227.1K |
| Jefferies Financial Group Inc. | $2.2M | 328,800 | 0.01% | 6q | -31.4%-$1.0M |
| CITIGROUP INC | $2.1M | 306,907 | 0.00% | 12q | +437.7%+$1.7M |
| RHUMBLINE ADVISERS | $2.0M | 299,975 | 0.00% | 9q | +16.0%+$282.2K |
| ALPS ADVISORS INC | $2.0M | 290,543 | 0.01% | 3q | +30.3%+$460.1K |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | $1.9M | 272,600 | 0.00% | 3q | +2.6%+$46.3K |
| JANE STREET GROUP, LLC | $1.8M | 228,355 | 0.00% | 5q | HELD |
| Invesco Ltd. | $1.8M | 264,379 | 0.00% | 9q | -28.2%-$705.8K |
| Ensign Peak Advisors, Inc | $1.8M | 262,896 | 0.00% | 3q | -52.2%-$2.0M |
| Qube Research & Technologies Ltd | $1.8M | 259,605 | 0.00% | new | NEW |
| SPHERA FUNDS MANAGEMENT LTD. | $1.7M | 250,000 | 0.22% | new | NEW |
| DEUTSCHE BANK AG\ | $1.7M | 243,379 | 0.00% | 9q | +33.9%+$419.6K |
| TWO SIGMA INVESTMENTS, LP | $1.6M | 234,716 | 0.00% | 5q | -68.4%-$3.5M |
| Monashee Investment Management LLC | $1.4M | 200,000 | 2.29% | new | NEW |
| Privium Fund Management B.V. | $1.4M | 198,900 | 0.25% | 9q | +9.3%+$115.8K |
| VICTORY CAPITAL MANAGEMENT INC | $1.3M | 197,578 | 0.00% | 11q | +0.9%+$12.5K |
| Chicago Partners Investment Group LLC | $1.3M | 222,347 | 0.03% | 12q | +30.2%+$300.8K |
| Balyasny Asset Management L.P. | $1.3M | 189,332 | 0.00% | 3q | +128.1%+$724.0K |
| STATE OF WISCONSIN INVESTMENT BOARD | $1.2M | 177,089 | 0.00% | 4q | -32.8%-$587.3K |
| RAYMOND JAMES FINANCIAL INC | $1.1M | 166,042 | 0.00% | 3q | +653.7%+$980.7K |
| ALLIANCEBERNSTEIN L.P. | $1.1M | 247,680 | 0.00% | 9q | +30.9%+$261.2K |
| WEXFORD CAPITAL LP | $1.1M | 160,654 | 0.14% | 4q | HELD |
| Rafferty Asset Management, LLC | $1.1M | 154,706 | 0.00% | 5q | -48.4%-$988.8K |
| Palumbo Wealth Management LLC | $1.0M | 149,173 | 0.21% | 4q | +1.7%+$16.8K |
| MetLife Investment Management, LLC | $959.2K | 140,846 | 0.00% | 9q | +17.3%+$141.2K |
| Vanguard Global Advisers, LLC | $911.3K | 133,821 | 0.00% | 2q | +14.7%+$116.7K |
| Persistent Asset Partners Ltd | $908.5K | 133,411 | 0.27% | new | NEW |
| VANGUARD ASSET MANAGEMENT, Ltd | $903.1K | 132,614 | 0.00% | 2q | +46.6%+$287.0K |
| AQR CAPITAL MANAGEMENT LLC | $876.9K | 128,764 | 0.00% | 8q | -27.4%-$330.6K |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | $869.7K | 127,915 | 0.00% | 8q | +2.6%+$21.7K |
| Mariner, LLC | $793.9K | 116,582 | 0.00% | new | NEW |
Five percent filings
Anyone crossing 5% of a company must say so within days - far sooner than the next quarterly holdings report. A 13D declares an intent to influence the company; a 13G is the passive version. See all activist filings →
| Filed | Form | Filer | % of class |
|---|---|---|---|
| 2026-08-14 | 13G/A | RA Capital Management, L.P.with 3 co-filers | 9.9% |
| 2026-08-13 | 13G/A | Morgan Stanleywith 1 co-filers | 5.1% |
Quarter by quarter
Coverage begins with the quarter ending 2018-12-31. Earlier filings exist only as occasional late amendments, too sparse to describe a market, so they are not shown.
| Quarter | Holders | Value | Shares | New | Added | Trimmed | Options |
|---|---|---|---|---|---|---|---|
| Q2 2026 | 202 | $2.1B | 303,886,741 | 38 | 96 | 41 | 0.3% |
| Q1 2026 | 189 | $1.2B | 263,776,221 | 24 | 66 | 46 | 0.2% |
| Q4 2025 | 188 | $1.5B | 267,741,807 | 62 | 57 | 40 | 0.6% |
| Q3 2025 | 144 | $866.8M | 264,248,068 | 25 | 53 | 30 | 0.3% |
| Q2 2025 | 141 | $595.1M | 257,375,144 | 41 | 42 | 32 | 0.1% |
| Q1 2025 | 121 | $231.8M | 166,588,441 | 20 | 31 | 29 | 0.1% |
| Q4 2024 | 123 | $289.4M | 167,194,133 | 22 | 40 | 24 | 0.1% |
| Q3 2024 | 108 | $320.6M | 159,468,002 | 26 | 39 | 14 | 0.0% |
| Q2 2024 | 99 | $357.8M | 159,589,848 | 31 | 27 | 20 | 0.1% |
| Q1 2024 | 100 | $427.1M | 148,564,513 | 32 | 28 | 22 | 0.2% |
| Q4 2023 | 79 | $219.5M | 123,864,122 | 22 | 29 | 8 | 0.1% |
| Q3 2023 | 60 | $394.2M | 124,427,986 | 36 | 9 | 7 | 0.3% |
| Q2 2023 | 34 | $7.9M | 11,925,474 | 3 | 8 | 7 | 0.0% |
| Q1 2023 | 33 | $13.6M | 17,079,441 | 3 | 10 | 8 | 0.0% |
| Q4 2022 | 41 | $35.2M | 15,484,137 | 12 | 14 | 7 | 0.6% |
| Q3 2022 | 53 | $27.2M | 13,929,748 | 2 | 11 | 21 | 0.7% |
| Q2 2022 | 58 | $54.8M | 14,701,866 | 15 | 14 | 23 | 0.2% |
| Q1 2022 | 71 | $111.2M | 17,015,374 | 14 | 26 | 15 | 0.2% |
| Q4 2021 | 64 | $215.6M | 18,503,405 | 20 | 22 | 6 | 0.0% |
| Q3 2021 | 48 | $361.9M | 19,436,846 | 4 | 19 | 11 | 0.0% |
| Q2 2021 | 48 | $395.2M | 18,641,071 | 10 | 26 | 3 | 0.0% |
| Q1 2021 | 46 | $358.5M | 17,661,042 | 3 | 16 | 13 | 0.0% |
| Q4 2020 | 51 | $475.2M | 17,998,603 | 23 | 8 | 8 | 0.0% |
| Q3 2020 | 46 | $366.7M | 16,580,732 | 46 | 0 | 0 | 0.0% |