PYXIS ONCOLOGY INC (PYXS)
Institutional ownership reported to the SEC as of Q2 2026, across 19 quarters.
78
Reporting holders
$107.7M
Reported value
42.9%
Of shares outstanding
1.6%
Held as options
+3
Holder change
Institutions report 35,757,035 shares against 83,408,050 outstanding. Shares only - option lines are excluded, which is why this can be compared with the company at all. The count comes from the cover page of the company's own most recent report, so it is dated when that was filed rather than at quarter end.
Options share is the part of reported value carried in derivative lines rather than shares. A high figure means institutions are expressing a view on this security without owning much of it.
Holders
| Filer | Value | Shares | Their book | Held | Change |
|---|---|---|---|---|---|
| GordonMD Global Investments LP | $30.2M | 10,024,909 | 14.60% | 3q | +143.2%+$17.8M |
| Pfizer Inc | $19.5M | 7,032,770 | 11.43% | 7q | HELD |
| Laurion Capital Management LP | $14.8M | 4,900,888 | 0.38% | 19q | -1.9%-$290.3K |
| Palo Alto Investors LP | $7.8M | 2,592,831 | 0.36% | 8q | +156.6%+$4.8M |
| VANGUARD CAPITAL MANAGEMENT LLC | $6.2M | 2,075,997 | 0.00% | 2q | +2.1%+$127.9K |
| Atle Fund Management AB | $2.9M | 966,459 | 0.78% | 3q | +390.5%+$2.3M |
| BlackRock, Inc. | $2.6M | 867,934 | 0.00% | 8q | +10.0%+$238.1K |
| MARSHALL WACE, LLP | $2.5M | 830,544 | 0.00% | 3q | +134.3%+$1.4M |
| RENAISSANCE TECHNOLOGIES LLC | $2.3M | 772,232 | 0.00% | 17q | -13.1%-$350.5K |
| GEODE CAPITAL MANAGEMENT, LLC | $1.8M | 591,849 | 0.00% | 19q | -1.0%-$18.9K |
| Woodline Partners LP | $1.6M | 523,999 | 0.00% | new | NEW |
| 683 Capital Management, LLC | $1.4M | 459,367 | 0.07% | 8q | -48.7%-$1.3M |
| JACOBS LEVY EQUITY MANAGEMENT, INC | $1.3M | 428,606 | 0.00% | 2q | -7.0%-$97.5K |
| DIADEMA PARTNERS LP | $1.2M | options only | 0.15% | new | OPTIONS |
| JANE STREET GROUP, LLC | $1.1M | 290,090 | 0.00% | 5q | -4.7%-$54.2K |
| Longaeva Partners L.P. | $1.1M | 353,582 | 0.02% | 4q | -29.7%-$450.4K |
| Decheng Capital LLC | $983.7K | 326,810 | 0.13% | 11q | HELD |
| VANGUARD FIDUCIARY TRUST CO | $912.0K | 302,986 | 0.00% | 2q | +0.7%+$6.3K |
| STATE STREET CORP | $749.0K | 248,837 | 0.00% | 19q | HELD |
| MILLENNIUM MANAGEMENT LLC | $701.3K | 233,004 | 0.00% | 11q | -41.4%-$495.5K |
| UBS Group AG | $467.2K | 155,217 | 0.00% | 14q | -38.9%-$297.7K |
| Bank of New York Mellon Corp | $403.3K | 133,996 | 0.00% | 14q | HELD |
| NORTHERN TRUST CORP | $373.1K | 123,959 | 0.00% | 19q | +21.6%+$66.3K |
| NewEdge Wealth, LLC | $349.2K | 116,006 | 0.00% | 8q | HELD |
| XTX Topco Ltd | $333.9K | 110,939 | 0.00% | 5q | -44.6%-$268.4K |
| TWO SIGMA INVESTMENTS, LP | $252.7K | 83,961 | 0.00% | 4q | +14.5%+$32.1K |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | $244.6K | 81,260 | 0.00% | 17q | HELD |
| BANK OF AMERICA CORP /DE/ | $242.2K | 80,464 | 0.00% | 19q | +378.8%+$191.6K |
| STIFEL FINANCIAL CORP | $212.0K | 70,437 | 0.00% | 2q | +39.4%+$59.9K |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $196.0K | options only | 0.00% | 13q | OPTIONS |
| CITADEL ADVISORS LLC | $186.7K | 47,317 | 0.00% | 4q | -22.7%-$55.0K |
| Cable Car Capital, LP | $185.4K | 61,606 | 0.00% | 11q | HELD |
| MYDA Advisors LLC | $150.5K | 50,000 | 0.02% | new | NEW |
| Qube Research & Technologies Ltd | $150.3K | 49,932 | 0.00% | 12q | +342.4%+$116.3K |
| UNIVERSITY OF CHICAGO | $146.7K | 48,731 | 0.03% | 15q | HELD |
| Quadrature Capital Ltd | $141.7K | 47,067 | 0.00% | new | NEW |
| GOLDMAN SACHS GROUP INC | $138.2K | 45,900 | 0.00% | 10q | -2.2%-$3.1K |
| Verdad Advisers, LP | $135.1K | 44,899 | 0.13% | new | NEW |
| LPL Financial LLC | $131.1K | 43,554 | 0.00% | 8q | +29.8%+$30.1K |
| COMMONWEALTH EQUITY SERVICES, LLC | $127.8K | 42,455 | 0.00% | 12q | +22.2%+$23.2K |
| J. Derek Lewis & Associates Inc. | $126.4K | 42,000 | 0.02% | 3q | -2.3%-$3.0K |
| SIMPLEX TRADING, LLC | $118.0K | 37,902 | 0.00% | 9q | +14881.0%+$117.2K |
| CITIGROUP INC | $115.0K | 38,205 | 0.00% | 10q | +2095.7%+$109.8K |
| Point72 Asset Management, L.P. | $111.6K | 37,092 | 0.00% | 3q | +15.9%+$15.3K |
| Walleye Capital LLC | $110.7K | 36,778 | 0.00% | new | NEW |
| DIMENSIONAL FUND ADVISORS LP | $108.9K | 36,175 | 0.00% | 14q | +39.6%+$30.9K |
| MORGAN STANLEY | $100.7K | 33,448 | 0.00% | 19q | -52.0%-$109.1K |
| GROUP ONE TRADING LLC | $99.3K | 16,480 | 0.00% | new | NEW |
| MACKENZIE FINANCIAL CORP | $79.3K | 26,343 | 0.00% | new | NEW |
| Cetera Investment Advisers | $75.2K | 25,000 | 0.00% | 13q | -8.3%-$6.8K |
| Graham Capital Management, L.P. | $68.4K | 22,708 | 0.00% | 3q | HELD |
| Vanguard Global Advisers, LLC | $63.9K | 21,242 | 0.00% | 2q | HELD |
| OSAIC HOLDINGS, INC. | $53.3K | 17,721 | 0.00% | 14q | +29.2%+$12.0K |
| Persistent Asset Partners Ltd | $49.5K | options only | 0.01% | new | OPTIONS |
| FMR LLC | $37.3K | 12,383 | 0.00% | 8q | +4.0%+$1.4K |
| PACES FERRY WEALTH ADVISORS, LLC | $34.4K | 11,440 | 0.01% | 3q | HELD |
| NewEdge Advisors, LLC | $30.9K | 10,250 | 0.00% | new | NEW |
| China Universal Asset Management Co., Ltd. | $30.4K | 10,083 | 0.00% | 7q | -8.7%-$2.9K |
| Tower Research Capital LLC (TRC) | $28.3K | 9,398 | 0.00% | 8q | -9.0%-$2.8K |
| MERCER GLOBAL ADVISORS INC /ADV | $27.5K | 9,150 | 0.00% | new | NEW |
| PNC Financial Services Group, Inc. | $19.6K | 6,500 | 0.00% | 2q | HELD |
| JPMORGAN CHASE & CO | $15.9K | 5,545 | 0.00% | 14q | +7.2%+$1.1K |
| HAGER INVESTMENT MANAGEMENT SERVICES, LLC | $15.1K | 5,000 | 0.01% | 2q | HELD |
| BARCLAYS PLC | $14.1K | 4,669 | 0.00% | 9q | -90.6%-$135.9K |
| Federation des caisses Desjardins du Quebec | $13.5K | 4,500 | 0.00% | new | NEW |
| FEDERATED HERMES, INC. | $8.9K | 2,962 | 0.00% | 3q | -6.9% |
| Mirae Asset Global Investments Co., Ltd. | $8.5K | 2,833 | 0.00% | 7q | -56.4%-$11.0K |
| BNP PARIBAS FINANCIAL MARKETS | $8.1K | 2,689 | 0.00% | 7q | +62.6%+$3.1K |
| FIRST UNITED BANK & TRUST | $7.4K | 2,500 | 0.00% | new | NEW |
| GF FUND MANAGEMENT CO. LTD. | $3.7K | 1,226 | 0.00% | 7q | -6.8% |
| NISA INVESTMENT ADVISORS, LLC | $2.9K | 961 | 0.00% | 6q | HELD |
| Physician Wealth Advisors, Inc. | $2.8K | 943 | 0.00% | 5q | HELD |
| SBI Securities Co., Ltd. | $1.5K | 509 | 0.00% | 7q | +50800.0%+$1.5K |
| JONES FINANCIAL COMPANIES LLLP | $1.4K | 500 | 0.00% | 9q | HELD |
| WELLS FARGO & COMPANY/MN | $858 | 285 | 0.00% | 15q | -50.0% |
| Cornerstone Financial Management LLC | $518 | 172 | 0.00% | 3q | HELD |
| ACADIAN ASSET MANAGEMENT LLC | $380 | 126,793 | 0.00% | 2q | -12.1% |
| Caitong International Asset Management Co., Ltd | $105 | 35 | 0.00% | 2q | +775.0% |
| Arax Advisory Partners | $42 | 14 | 0.00% | 4q | +1300.0% |
| Winthrop Capital Management, LLC | $18 | 6,000 | 0.00% | 7q | HELD |
Five percent filings
Anyone crossing 5% of a company must say so within days - far sooner than the next quarterly holdings report. A 13D declares an intent to influence the company; a 13G is the passive version. See all activist filings →
| Filed | Form | Filer | % of class |
|---|---|---|---|
| 2026-07-10 | 13G | BVF PARTNERS L P/ILwith 9 co-filers | 10.0% |
| 2026-07-02 | 13G/A | GordonMD Global Investments LPwith 3 co-filers | 12.1% |
Quarter by quarter
Coverage begins with the quarter ending 2018-12-31. Earlier filings exist only as occasional late amendments, too sparse to describe a market, so they are not shown.
| Quarter | Holders | Value | Shares | New | Added | Trimmed | Options |
|---|---|---|---|---|---|---|---|
| Q2 2026 | 78 | $107.7M | 35,757,035 | 14 | 25 | 23 | 1.6% |
| Q1 2026 | 75 | $40.6M | 27,412,901 | 11 | 10 | 34 | 0.7% |
| Q4 2025 | 77 | $35.3M | 30,150,296 | 21 | 23 | 18 | 1.9% |
| Q3 2025 | 69 | $59.8M | 26,700,626 | 15 | 9 | 28 | 0.5% |
| Q2 2025 | 68 | $30.1M | 27,388,176 | 14 | 18 | 21 | 0.1% |
| Q1 2025 | 84 | $29.6M | 30,096,156 | 10 | 16 | 23 | 0.2% |
| Q4 2024 | 96 | $50.7M | 31,501,503 | 21 | 28 | 18 | 3.1% |
| Q3 2024 | 84 | $104.3M | 27,825,388 | 19 | 27 | 14 | 2.1% |
| Q2 2024 | 75 | $94.2M | 27,949,623 | 19 | 19 | 21 | 1.7% |
| Q1 2024 | 66 | $96.9M | 22,594,560 | 27 | 21 | 4 | 0.7% |
| Q4 2023 | 48 | $15.2M | 8,411,217 | 7 | 9 | 10 | 0.2% |
| Q3 2023 | 44 | $14.1M | 7,079,813 | 10 | 14 | 10 | 0.3% |
| Q2 2023 | 43 | $23.3M | 9,069,541 | 16 | 16 | 6 | 0.3% |
| Q1 2023 | 39 | $39.3M | 9,791,101 | 21 | 5 | 5 | 0.0% |
| Q4 2022 | 24 | $25.0M | 18,682,983 | 3 | 8 | 2 | 0.0% |
| Q3 2022 | 35 | $38.3M | 19,443,728 | 4 | 11 | 5 | 0.0% |
| Q2 2022 | 37 | $47.7M | 20,034,321 | 11 | 8 | 11 | 0.0% |
| Q1 2022 | 45 | $76.1M | 18,946,126 | 4 | 13 | 14 | 0.0% |
| Q4 2021 | 51 | $221.2M | 20,282,742 | 50 | 0 | 0 | 0.0% |