PYXIS ONCOLOGY INC (PYXS)
Institutional ownership reported to the SEC as of Q2 2026, across 19 quarters.
Institutions report 36,186,154 shares against 83,408,050 outstanding. Shares only - option lines are excluded, which is why this can be compared with the company at all. The count comes from the cover page of the company's own most recent report, so it is dated when that was filed rather than at quarter end.
Calls and puts are the parts of reported value carried in derivative lines rather than shares, and they point in opposite directions: a manager holding calls is positioned for the security, one holding puts against it - or hedging shares they already own, which is why index funds carry so many. Most sites add the two together and report one figure, which averages away the only interesting part.
Holders
| Filer | Value | Shares | Their book | Held | Change |
|---|---|---|---|---|---|
| GordonMD Global Investments LP | $30.2M | 10,024,909 | 14.60% | 3q | +143.2%+$17.8M |
| Pfizer Inc | $19.5M | 7,032,770 | 11.43% | 7q | HELD |
| Laurion Capital Management LP | $14.8M | 4,900,888 | 0.38% | 19q | -1.9%-$290.3K |
| Palo Alto Investors LP | $7.8M | 2,592,831 | 0.36% | 8q | +156.6%+$4.8M |
| VANGUARD CAPITAL MANAGEMENT LLC | $6.2M | 2,075,997 | 0.00% | 2q | +2.1%+$127.9K |
| Atle Fund Management AB | $2.9M | 966,459 | 0.78% | 3q | +390.5%+$2.3M |
| BlackRock, Inc. | $2.6M | 867,934 | 0.00% | 8q | +10.0%+$238.1K |
| MARSHALL WACE, LLP | $2.5M | 830,544 | 0.00% | 3q | +134.3%+$1.4M |
| RENAISSANCE TECHNOLOGIES LLC | $2.3M | 772,232 | 0.00% | 17q | -13.1%-$350.5K |
| GEODE CAPITAL MANAGEMENT, LLC | $1.8M | 591,849 | 0.00% | 19q | -1.0%-$18.9K |
| Woodline Partners LP | $1.6M | 523,999 | 0.00% | new | NEW |
| STATE STREET CORP | $1.5M | 497,674 | 0.00% | 19q | +100.0%+$749.0K |
| 683 Capital Management, LLC | $1.4M | 459,367 | 0.07% | 8q | -48.7%-$1.3M |
| JACOBS LEVY EQUITY MANAGEMENT, INC | $1.3M | 428,606 | 0.00% | 2q | -7.0%-$97.5K |
| DIADEMA PARTNERS LP | $1.2M | options only | 0.15% | new | OPTIONS |
| JANE STREET GROUP, LLC | $1.1M | 290,090 | 0.00% | 5q | -4.7%-$54.2K |
| Longaeva Partners L.P. | $1.1M | 353,582 | 0.02% | 4q | -29.7%-$450.4K |
| Decheng Capital LLC | $983.7K | 326,810 | 0.13% | 11q | HELD |
| VANGUARD FIDUCIARY TRUST CO | $912.0K | 302,986 | 0.00% | 2q | +0.7%+$6.3K |
| MILLENNIUM MANAGEMENT LLC | $701.3K | 233,004 | 0.00% | 11q | -41.4%-$495.5K |
| UBS Group AG | $467.2K | 155,217 | 0.00% | 14q | -38.9%-$297.7K |
| Bank of New York Mellon Corp | $403.3K | 133,996 | 0.00% | 14q | HELD |
| ACADIAN ASSET MANAGEMENT LLC | $380.0K | 126,793 | 0.00% | 2q | -12.1%-$52.3K |
| CITADEL ADVISORS LLC | $373.3K | 94,634 | 0.00% | 4q | +54.5%+$131.7K |
| NORTHERN TRUST CORP | $373.1K | 123,959 | 0.00% | 19q | +21.6%+$66.3K |
| NewEdge Wealth, LLC | $349.2K | 116,006 | 0.00% | 8q | HELD |
| XTX Topco Ltd | $333.9K | 110,939 | 0.00% | 5q | -44.6%-$268.4K |
| TWO SIGMA INVESTMENTS, LP | $252.7K | 83,961 | 0.00% | 4q | +14.5%+$32.1K |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | $244.6K | 81,260 | 0.00% | 17q | HELD |
| BANK OF AMERICA CORP /DE/ | $242.2K | 80,464 | 0.00% | 19q | +378.8%+$191.6K |
| STIFEL FINANCIAL CORP | $212.0K | 70,437 | 0.00% | 2q | +39.4%+$59.9K |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $196.0K | options only | 0.00% | 13q | OPTIONS |
| Cable Car Capital, LP | $185.4K | 61,606 | 0.00% | 11q | HELD |
| MYDA Advisors LLC | $150.5K | 50,000 | 0.02% | new | NEW |
| Qube Research & Technologies Ltd | $150.3K | 49,932 | 0.00% | 12q | +342.4%+$116.3K |
| UNIVERSITY OF CHICAGO | $146.7K | 48,731 | 0.03% | 15q | HELD |
| Quadrature Capital Ltd | $141.7K | 47,067 | 0.00% | new | NEW |
| GOLDMAN SACHS GROUP INC | $138.2K | 45,900 | 0.00% | 10q | -2.2%-$3.1K |
| Verdad Advisers, LP | $135.1K | 44,899 | 0.13% | new | NEW |
| LPL Financial LLC | $131.1K | 43,554 | 0.00% | 8q | +29.8%+$30.1K |
| COMMONWEALTH EQUITY SERVICES, LLC | $127.8K | 42,455 | 0.00% | 12q | +22.2%+$23.2K |
| J. Derek Lewis & Associates Inc. | $126.4K | 42,000 | 0.02% | 3q | -2.3%-$3.0K |
| SIMPLEX TRADING, LLC | $118.0K | 37,902 | 0.00% | 9q | +14881.0%+$117.2K |
| CITIGROUP INC | $115.0K | 38,205 | 0.00% | 10q | +2095.7%+$109.8K |
| Point72 Asset Management, L.P. | $111.6K | 37,092 | 0.00% | 3q | +15.9%+$15.3K |
| Walleye Capital LLC | $110.7K | 36,778 | 0.00% | new | NEW |
| DIMENSIONAL FUND ADVISORS LP | $108.9K | 36,175 | 0.00% | 14q | +39.6%+$30.9K |
| MORGAN STANLEY | $100.7K | 33,448 | 0.00% | 19q | -52.0%-$109.1K |
| GROUP ONE TRADING LLC | $99.3K | 16,480 | 0.00% | new | NEW |
| MACKENZIE FINANCIAL CORP | $79.3K | 26,343 | 0.00% | new | NEW |
| Cetera Investment Advisers | $75.2K | 25,000 | 0.00% | 13q | -8.3%-$6.8K |
| Graham Capital Management, L.P. | $68.4K | 22,708 | 0.00% | 3q | HELD |
| Vanguard Global Advisers, LLC | $63.9K | 21,242 | 0.00% | 2q | HELD |
| OSAIC HOLDINGS, INC. | $53.3K | 17,721 | 0.00% | 14q | +29.2%+$12.0K |
| Persistent Asset Partners Ltd | $49.5K | options only | 0.01% | new | OPTIONS |
| FMR LLC | $37.3K | 12,383 | 0.00% | 8q | +4.0%+$1.4K |
| PACES FERRY WEALTH ADVISORS, LLC | $34.4K | 11,440 | 0.01% | 3q | HELD |
| NewEdge Advisors, LLC | $30.9K | 10,250 | 0.00% | new | NEW |
| China Universal Asset Management Co., Ltd. | $30.4K | 10,083 | 0.00% | 7q | -8.7%-$2.9K |
| Tower Research Capital LLC (TRC) | $28.3K | 9,398 | 0.00% | 8q | -9.0%-$2.8K |
| MERCER GLOBAL ADVISORS INC /ADV | $27.5K | 9,150 | 0.00% | new | NEW |
| PNC Financial Services Group, Inc. | $19.6K | 6,500 | 0.00% | 2q | HELD |
| Winthrop Capital Management, LLC | $18.0K | 6,000 | 0.00% | 7q | HELD |
| JPMORGAN CHASE & CO | $15.9K | 5,545 | 0.00% | 14q | +7.2%+$1.1K |
| HAGER INVESTMENT MANAGEMENT SERVICES, LLC | $15.1K | 5,000 | 0.01% | 2q | HELD |
| BARCLAYS PLC | $14.1K | 4,669 | 0.00% | 9q | -90.6%-$135.9K |
| Federation des caisses Desjardins du Quebec | $13.5K | 4,500 | 0.00% | new | NEW |
| FEDERATED HERMES, INC. | $8.9K | 2,962 | 0.00% | 3q | -6.9% |
| Mirae Asset Global Investments Co., Ltd. | $8.5K | 2,833 | 0.00% | 7q | -56.4%-$11.0K |
| BNP PARIBAS FINANCIAL MARKETS | $8.1K | 2,689 | 0.00% | 7q | +62.6%+$3.1K |
| FIRST UNITED BANK & TRUST | $7.4K | 2,500 | 0.00% | new | NEW |
| GF FUND MANAGEMENT CO. LTD. | $3.7K | 1,226 | 0.00% | 7q | -6.8% |
| NISA INVESTMENT ADVISORS, LLC | $2.9K | 961 | 0.00% | 6q | HELD |
| Physician Wealth Advisors, Inc. | $2.8K | 943 | 0.00% | 5q | HELD |
| SBI Securities Co., Ltd. | $1.5K | 509 | 0.00% | 7q | +50800.0%+$1.5K |
| JONES FINANCIAL COMPANIES LLLP | $1.4K | 500 | 0.00% | 9q | HELD |
| Cornerstone Financial Management LLC | $1.0K | 344 | 0.00% | 3q | HELD |
| WELLS FARGO & COMPANY/MN | $858 | 285 | 0.00% | 15q | -50.0% |
| Caitong International Asset Management Co., Ltd | $105 | 35 | 0.00% | 2q | +775.0% |
| Arax Advisory Partners | $42 | 14 | 0.00% | 4q | +1300.0% |
Five percent filings
Anyone crossing 5% of a company must say so within days - far sooner than the next quarterly holdings report. A 13D declares an intent to influence the company; a 13G is the passive version. See all activist filings →
| Filed | Form | Filer | % of class |
|---|---|---|---|
| 2026-10-09 | 13G/A | GordonMD Global Investments LPwith 3 co-filers | 16.4% |
| 2026-10-05 | 13G | Coastlands Capital LPwith 4 co-filers | 5.4% |
| 2026-10-02 | 13G/A | GordonMD Global Investments LPwith 3 co-filers | 17.5% |
| 2026-07-10 | 13G | BVF PARTNERS L P/ILwith 9 co-filers | 10.0% |
| 2026-07-02 | 13G/A | GordonMD Global Investments LPwith 3 co-filers | 12.1% |
What the company announced
Form 8-K filings from the last 120 days, showing only the items worth a reader's attention. Earnings releases, exhibit attachments and general disclosures are filed constantly and are left out. Filed is when the SEC received it; event is the date the company says the thing happened.
| Filed | Event date | What | Source |
|---|---|---|---|
| 2026-10-01 | 2026-09-29 | Material agreement entered | filing |
| 2026-09-08 | 2026-09-03 | Directors or officers departed or appointed | filing |
What the insiders did
Open market purchases and sales reported on Form 4 in the last 180 days. Grants, option exercises and shares surrendered to cover tax are left out: they are compensation rather than a decision to buy or sell. Where a broker filled one order in tranches the lines are summed, because it was one decision.
Officers and directors
| Date | Insider | Role | Side | Shares | Value |
|---|---|---|---|---|---|
| 2026-06-30 | Dupont Jakob | Director | Sold | 35,000 | $107.1K |
Quarter by quarter
Coverage begins with the quarter ending 2018-12-31. Earlier filings exist only as occasional late amendments, too sparse to describe a market, so they are not shown.
| Quarter | Holders | Value | Shares | New | Added | Trimmed | Options |
|---|---|---|---|---|---|---|---|
| Q2 2026 | 80 | $109.0M | 36,186,154 | 14 | 27 | 23 | 1.6% |
| Q1 2026 | 77 | $40.8M | 27,563,329 | 12 | 10 | 34 | 0.7% |
| Q4 2025 | 79 | $35.4M | 30,196,117 | 21 | 24 | 18 | 1.9% |
| Q3 2025 | 74 | $60.1M | 26,834,108 | 15 | 10 | 31 | 0.6% |
| Q2 2025 | 74 | $30.3M | 27,544,092 | 15 | 21 | 22 | 0.1% |
| Q1 2025 | 90 | $29.7M | 30,265,629 | 12 | 19 | 23 | 0.3% |
| Q4 2024 | 99 | $50.3M | 31,195,278 | 21 | 29 | 19 | 3.3% |
| Q3 2024 | 90 | $104.7M | 27,904,031 | 22 | 27 | 16 | 2.2% |
| Q2 2024 | 79 | $94.8M | 28,138,911 | 22 | 20 | 22 | 1.8% |
| Q1 2024 | 71 | $98.8M | 23,015,232 | 30 | 22 | 5 | 0.8% |
| Q4 2023 | 51 | $15.9M | 8,799,595 | 7 | 10 | 11 | 0.2% |
| Q3 2023 | 49 | $15.3M | 7,689,414 | 11 | 15 | 13 | 0.3% |
| Q2 2023 | 46 | $24.7M | 9,605,170 | 18 | 18 | 6 | 0.3% |
| Q1 2023 | 47 | $41.5M | 10,354,999 | 24 | 7 | 7 | 0.0% |
| Q4 2022 | 31 | $26.5M | 19,762,209 | 3 | 10 | 5 | 0.0% |
| Q3 2022 | 35 | $38.3M | 19,443,728 | 4 | 11 | 5 | 0.0% |
| Q2 2022 | 37 | $47.7M | 20,034,321 | 11 | 8 | 11 | 0.0% |
| Q1 2022 | 45 | $76.1M | 18,946,126 | 4 | 13 | 14 | 0.0% |
| Q4 2021 | 51 | $221.2M | 20,282,742 | 50 | 0 | 0 | 0.0% |