PRIME MEDICINE INC (PRME)
Institutional ownership reported to the SEC as of Q2 2026, across 18 quarters.
182
Reporting holders
$377.9M
Reported value
55.6%
Of shares outstanding
1.5%
Held as options
+0
Holder change
Institutions report 100,891,056 shares against 181,376,856 outstanding. Shares only - option lines are excluded, which is why this can be compared with the company at all. The count comes from the cover page of the company's own most recent report, so it is dated when that was filed rather than at quarter end.
Options share is the part of reported value carried in derivative lines rather than shares. A high figure means institutions are expressing a view on this security without owning much of it.
Holders
| Filer | Value | Shares | Their book | Held | Change |
|---|---|---|---|---|---|
| Alphabet Inc. | $61.1M | 16,562,498 | 0.06% | 15q | HELD |
| BlackRock, Inc. | $35.4M | 9,602,041 | 0.00% | 8q | +12.9%+$4.1M |
| ARK Investment Management LLC | $30.8M | 8,348,746 | 0.20% | 15q | +33.6%+$7.8M |
| STATE STREET CORP | $28.0M | 7,576,460 | 0.00% | 15q | +19.4%+$4.5M |
| VANGUARD CAPITAL MANAGEMENT LLC | $16.7M | 4,522,640 | 0.00% | 2q | +1.1%+$178.9K |
| Balyasny Asset Management L.P. | $14.6M | 3,969,082 | 0.02% | 4q | -3.7%-$569.3K |
| GOLDMAN SACHS GROUP INC | $12.7M | 3,430,518 | 0.00% | 12q | +253.5%+$9.1M |
| Casdin Capital, LLC | $11.7M | 3,167,175 | 0.58% | 15q | HELD |
| Woodline Partners LP | $11.1M | 3,003,904 | 0.03% | 4q | HELD |
| UBS Group AG | $10.3M | 2,794,689 | 0.00% | 15q | -3.2%-$345.9K |
| GEODE CAPITAL MANAGEMENT, LLC | $10.0M | 2,712,446 | 0.00% | 15q | -1.1%-$115.4K |
| Sumitomo Mitsui Trust Group, Inc. | $8.9M | 2,412,984 | 0.01% | 15q | -17.9%-$1.9M |
| Amova Asset Management Americas, Inc. | $8.9M | 2,407,018 | 0.11% | 15q | -18.2%-$2.0M |
| CITADEL ADVISORS LLC | $8.7M | 2,054,543 | 0.00% | 12q | +510.8%+$7.3M |
| ADAR1 Capital Management, LLC | $7.4M | 1,997,552 | 0.34% | 2q | +1.2%+$89.6K |
| FMR LLC | $6.5M | 1,761,884 | 0.00% | 15q | HELD |
| TWO SIGMA INVESTMENTS, LP | $5.6M | 1,524,511 | 0.00% | 12q | -3.1%-$178.2K |
| Redmile Group, LLC | $5.1M | 1,389,632 | 0.34% | 2q | -12.6%-$742.4K |
| FARALLON CAPITAL MANAGEMENT, L.L.C. | $4.6M | 1,240,843 | 0.02% | 10q | HELD |
| Jump Financial, LLC | $4.6M | 1,240,429 | 0.04% | new | NEW |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $4.5M | 648,479 | 0.00% | 11q | -9.4%-$469.8K |
| BANK OF AMERICA CORP /DE/ | $3.6M | 981,335 | 0.00% | 15q | +70.1%+$1.5M |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $3.5M | 961,826 | 0.00% | 2q | +11.6%+$367.6K |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $3.4M | 927,538 | 0.00% | 15q | +1.1%+$38.1K |
| Sixth Street Partners Management Company, L.P. | $3.4M | 927,538 | 0.00% | new | NEW |
| NORTHERN TRUST CORP | $3.4M | 912,597 | 0.00% | 15q | +2.9%+$95.5K |
| JPMORGAN CHASE & CO | $3.0M | 810,095 | 0.00% | 15q | -4.0%-$126.7K |
| VANGUARD FIDUCIARY TRUST CO | $2.8M | 764,633 | 0.00% | 2q | +6.6%+$175.8K |
| MORGAN STANLEY | $2.6M | 708,963 | 0.00% | 15q | +10.9%+$256.5K |
| Alessandra Capital Management, LLC | $2.5M | 666,603 | 1.74% | 2q | +56.7%+$889.6K |
| D. E. Shaw & Co., Inc. | $2.4M | 648,940 | 0.00% | 4q | -53.4%-$2.7M |
| Point72 Asset Management, L.P. | $2.0M | 533,553 | 0.00% | new | NEW |
| MOORE CAPITAL MANAGEMENT, LP | $1.8M | 500,000 | 0.03% | 10q | HELD |
| CHELSEA COUNSEL CO | $1.7M | 449,060 | 0.70% | 15q | +97.8%+$819.4K |
| MILLENNIUM MANAGEMENT LLC | $1.6M | 427,097 | 0.00% | new | NEW |
| HighTower Advisors, LLC | $1.3M | 340,365 | 0.00% | 13q | HELD |
| DIMENSIONAL FUND ADVISORS LP | $1.1M | 304,678 | 0.00% | 3q | HELD |
| WELLINGTON MANAGEMENT GROUP LLP | $1.1M | 304,444 | 0.00% | 4q | +9.5%+$97.1K |
| Nuveen, LLC | $1.0M | 275,931 | 0.00% | 6q | HELD |
| JANE STREET GROUP, LLC | $1.0M | options only | 0.00% | 5q | OPTIONS |
| WELLS FARGO & COMPANY/MN | $928.9K | 251,747 | 0.00% | 14q | -60.6%-$1.4M |
| SIMPLEX TRADING, LLC | $925.1K | options only | 0.00% | 11q | OPTIONS |
| Bank of New York Mellon Corp | $909.0K | 246,344 | 0.00% | 15q | -7.8%-$77.0K |
| IQ EQ FUND MANAGEMENT (IRELAND) Ltd | $833.2K | 225,799 | 0.05% | 9q | +9.9%+$75.3K |
| MARSHALL WACE, LLP | $800.1K | 216,841 | 0.00% | 2q | +52.8%+$276.3K |
| XTX Topco Ltd | $796.0K | 215,708 | 0.01% | 5q | +37.1%+$215.6K |
| Jain Global LLC | $794.2K | 215,218 | 0.00% | new | NEW |
| JUPITER ASSET MANAGEMENT LTD | $773.0K | 209,490 | 0.00% | new | NEW |
| Swiss National Bank | $768.6K | 208,300 | 0.00% | 3q | +16.6%+$109.6K |
| PEAK6 LLC | $767.7K | 208,057 | 0.00% | new | NEW |
| CITIGROUP INC | $722.0K | 195,664 | 0.00% | 15q | +314.3%+$547.7K |
| Green Alpha Advisors, LLC | $682.7K | 185,023 | 0.46% | 7q | -3.2%-$22.7K |
| Keystone Financial Group | $614.4K | 166,510 | 0.04% | 4q | HELD |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | $599.5K | 162,338 | 0.00% | 9q | +32.6%+$147.3K |
| Rafferty Asset Management, LLC | $536.1K | 145,275 | 0.00% | 3q | -32.6%-$259.4K |
| GROUP ONE TRADING LLC | $527.7K | options only | 0.00% | 11q | OPTIONS |
| ALLIANCEBERNSTEIN L.P. | $523.0K | 150,300 | 0.00% | 13q | +22.7%+$96.9K |
| Invesco Ltd. | $517.7K | 140,308 | 0.00% | 10q | +44.8%+$160.3K |
| Concurrent Investment Advisors, LLC | $486.1K | 131,722 | 0.00% | 2q | +77.6%+$212.3K |
| ExodusPoint Capital Management, LP | $437.1K | 118,464 | 0.00% | new | NEW |
| AQR CAPITAL MANAGEMENT LLC | $435.4K | 117,998 | 0.00% | 7q | -78.7%-$1.6M |
| Virtus Investment Advisers, LLC | $435.1K | 117,909 | 0.10% | 3q | +77.3%+$189.7K |
| RENAISSANCE TECHNOLOGIES LLC | $433.2K | 117,412 | 0.00% | 6q | -84.2%-$2.3M |
| RHUMBLINE ADVISERS | $430.8K | 116,754 | 0.00% | 13q | +2.2%+$9.2K |
| FIL Ltd | $425.1K | 115,206 | 0.00% | 15q | HELD |
| DEUTSCHE BANK AG\ | $422.4K | 114,472 | 0.00% | 15q | -27.3%-$158.6K |
| Steward Partners Investment Advisory, LLC | $399.6K | 108,290 | 0.00% | 4q | -7.8%-$33.8K |
| Palumbo Wealth Management LLC | $383.0K | 103,801 | 0.08% | 6q | +1.5%+$5.7K |
| MILESTONE ASSET MANAGEMENT, LLC | $369.1K | 100,035 | 0.06% | new | NEW |
| TD Asset Management Inc | $347.4K | 94,148 | 0.00% | 15q | HELD |
| LPL Financial LLC | $340.1K | 92,174 | 0.00% | 6q | +38.8%+$95.0K |
| Rockefeller Capital Management L.P. | $334.8K | 90,735 | 0.00% | 4q | -0.7%-$2.5K |
| BARCLAYS PLC | $324.9K | 88,058 | 0.00% | 15q | +38.1%+$89.6K |
| Squarepoint Ops LLC | $324.8K | 88,029 | 0.00% | 5q | -6.4%-$22.3K |
| COMMONWEALTH EQUITY SERVICES, LLC | $322.2K | 87,310 | 0.00% | 5q | +431.2%+$261.5K |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | $314.8K | 85,300 | 0.00% | 3q | HELD |
| LOS ANGELES CAPITAL MANAGEMENT LLC | $303.7K | 82,305 | 0.00% | 2q | +56.4%+$109.6K |
| Corient Private Wealth LP | $286.9K | 77,762 | 0.00% | 4q | +88.6%+$134.8K |
| PROFUND ADVISORS LLC | $268.0K | 72,624 | 0.01% | 3q | -24.2%-$85.5K |
| Legal & General Group Plc | $245.2K | 66,444 | 0.00% | 15q | HELD |
| BNP PARIBAS FINANCIAL MARKETS | $243.9K | 66,101 | 0.00% | 7q | +92.1%+$116.9K |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | $239.1K | 64,800 | 0.00% | 5q | -51.9%-$258.3K |
| Jupiter Topco LLC | $224.4K | 60,900 | 0.00% | new | FIRST |
| Engineers Gate Manager LP | $218.2K | 59,133 | 0.00% | 4q | -46.4%-$189.0K |
| VANGUARD ASSET MANAGEMENT, Ltd | $217.8K | 59,021 | 0.00% | 2q | HELD |
| &PARTNERS | $210.6K | 57,460 | 0.00% | 4q | -3.4%-$7.4K |
| MetLife Investment Management, LLC | $207.3K | 56,192 | 0.00% | 5q | +27.1%+$44.2K |
| Russell Investments Group, Ltd. | $188.2K | 50,994 | 0.00% | 9q | -20.7%-$49.0K |
| AMERIPRISE FINANCIAL INC | $184.3K | 49,941 | 0.00% | 4q | -49.6%-$181.6K |
| Mutual Advisors, LLC | $166.1K | 45,000 | 0.00% | 5q | HELD |
| Vanguard Global Advisers, LLC | $163.4K | 44,269 | 0.00% | 2q | HELD |
| Quadrature Capital Ltd | $161.1K | 43,663 | 0.00% | 4q | -6.9%-$11.9K |
| IvyRock Asset Management (HK) Ltd | $154.2K | 41,800 | 0.09% | 4q | HELD |
| JONES FINANCIAL COMPANIES LLLP | $140.2K | 40,867 | 0.00% | 4q | +1.4%+$1.9K |
| State of New Jersey Common Pension Fund D | $123.9K | 33,569 | 0.00% | 2q | +8.8%+$10.1K |
| Crestwood Advisors Group, LLC | $118.2K | 32,041 | 0.00% | 7q | -1.0%-$1.2K |
| Police & Firemen's Retirement System of New Jersey | $113.5K | 30,751 | 0.00% | 7q | HELD |
| OPPENHEIMER & CO INC | $109.4K | 29,650 | 0.00% | 3q | -11.9%-$14.8K |
| RAYMOND JAMES FINANCIAL INC | $107.7K | 29,184 | 0.00% | 5q | +142.3%+$63.2K |
| SEI INVESTMENTS CO | $107.7K | 29,183 | 0.00% | 2q | HELD |
Showing the largest 100 of 191 reported holders.
Quarter by quarter
Coverage begins with the quarter ending 2018-12-31. Earlier filings exist only as occasional late amendments, too sparse to describe a market, so they are not shown.
| Quarter | Holders | Value | Shares | New | Added | Trimmed | Options |
|---|---|---|---|---|---|---|---|
| Q2 2026 | 182 | $377.9M | 100,891,056 | 23 | 54 | 62 | 1.5% |
| Q1 2026 | 182 | $323.9M | 91,297,555 | 30 | 65 | 44 | 2.0% |
| Q4 2025 | 173 | $316.2M | 88,957,374 | 41 | 57 | 42 | 2.4% |
| Q3 2025 | 156 | $466.9M | 81,578,539 | 53 | 58 | 27 | 3.2% |
| Q2 2025 | 110 | $127.0M | 50,569,465 | 24 | 31 | 30 | 1.6% |
| Q1 2025 | 117 | $106.6M | 53,275,927 | 22 | 32 | 31 | 0.3% |
| Q4 2024 | 120 | $168.3M | 57,384,776 | 26 | 33 | 30 | 0.4% |
| Q3 2024 | 105 | $242.8M | 62,132,140 | 11 | 36 | 28 | 1.0% |
| Q2 2024 | 108 | $322.1M | 62,497,081 | 22 | 38 | 26 | 0.3% |
| Q1 2024 | 99 | $420.3M | 59,929,041 | 17 | 35 | 26 | 0.2% |
| Q4 2023 | 93 | $405.7M | 45,681,133 | 21 | 21 | 23 | 0.2% |
| Q3 2023 | 75 | $447.1M | 46,866,116 | 10 | 30 | 12 | 0.0% |
| Q2 2023 | 70 | $638.3M | 43,574,669 | 16 | 31 | 11 | 0.0% |
| Q1 2023 | 62 | $591.9M | 48,228,134 | 12 | 27 | 3 | 0.0% |
| Q4 2022 | 55 | $704.6M | 37,923,219 | 54 | 0 | 0 | 0.0% |
| Q2 2019 | 4 | $1.1M | 53,032 | 1 | 2 | 0 | 0.0% |
| Q1 2019 | 4 | $882.0K | 42,217 | 1 | 0 | 1 | 0.0% |
| Q4 2018 | 5 | $494.0K | 27,533 | 0 | 0 | 0 | 0.0% |