OPKO HEALTH INC (OPK)
Institutional ownership reported to the SEC as of Q2 2026, across 31 quarters.
221
Reporting holders
$307.8M
Reported value
27.4%
Of shares outstanding
0.3%
Held as options
-2
Holder change
Institutions report 204,720,611 shares against 746,328,225 outstanding. Shares only - option lines are excluded, which is why this can be compared with the company at all. The count comes from the cover page of the company's own most recent report, so it is dated when that was filed rather than at quarter end.
Options share is the part of reported value carried in derivative lines rather than shares. A high figure means institutions are expressing a view on this security without owning much of it.
Holders
| Filer | Value | Shares | Their book | Held | Change |
|---|---|---|---|---|---|
| Rubric Capital Management LP | $71.7M | 47,791,243 | 0.66% | 10q | HELD |
| BlackRock, Inc. | $55.5M | 36,978,893 | 0.00% | 8q | +2.1%+$1.1M |
| VANGUARD CAPITAL MANAGEMENT LLC | $22.5M | 14,968,930 | 0.00% | 2q | +3.2%+$704.6K |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $22.4M | 14,934,924 | 0.00% | 2q | +1.1%+$247.8K |
| GEODE CAPITAL MANAGEMENT, LLC | $17.4M | 11,581,027 | 0.00% | 31q | +2.5%+$419.4K |
| STATE STREET CORP | $15.5M | 10,309,070 | 0.00% | 31q | +8.5%+$1.2M |
| GOLDMAN SACHS GROUP INC | $10.6M | 7,035,492 | 0.00% | 31q | -8.3%-$959.3K |
| UBS Group AG | $7.5M | 5,006,284 | 0.00% | 31q | -17.5%-$1.6M |
| Whitefort Capital Management, LP | $6.8M | 4,511,412 | 1.67% | 5q | +6.1%+$387.1K |
| NORTHERN TRUST CORP | $5.6M | 3,756,163 | 0.00% | 31q | +3.8%+$205.2K |
| HIGHBRIDGE CAPITAL MANAGEMENT LLC | $5.4M | 3,593,925 | 0.13% | new | NEW |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $5.4M | 3,596,980 | 0.00% | 31q | +0.6%+$34.4K |
| Sixth Street Partners Management Company, L.P. | $5.4M | 3,596,980 | 0.00% | new | NEW |
| VANGUARD FIDUCIARY TRUST CO | $4.1M | 2,706,235 | 0.00% | 2q | -1.3%-$53.7K |
| AWM Investment Company, Inc. | $3.2M | 2,110,000 | 0.27% | 25q | HELD |
| MORGAN STANLEY | $3.0M | 1,975,027 | 0.00% | 35q | +65.1%+$1.2M |
| CITADEL ADVISORS LLC | $2.4M | 1,420,922 | 0.00% | 31q | -31.7%-$1.1M |
| WASHINGTON GROWTH STRATEGIES LLC | $2.0M | 1,356,124 | 1.13% | 7q | HELD |
| Bank of New York Mellon Corp | $2.0M | 1,329,974 | 0.00% | 31q | +3.9%+$74.9K |
| DIMENSIONAL FUND ADVISORS LP | $1.9M | 1,267,741 | 0.00% | 31q | -18.7%-$438.5K |
| Y.D. More Investments Ltd | $1.9M | 1,257,568 | 0.06% | 9q | -3.2%-$62.5K |
| AQR CAPITAL MANAGEMENT LLC | $1.9M | 1,239,399 | 0.00% | 12q | +62.3%+$713.7K |
| OP Asset Management Ltd | $1.7M | 1,159,647 | 0.02% | 2q | +5.2%+$86.1K |
| VOYA INVESTMENT MANAGEMENT LLC | $1.6M | 1,094,111 | 0.00% | 31q | -5.8%-$100.2K |
| Clearstead Advisors, LLC | $1.3M | 883,288 | 0.01% | 9q | HELD |
| Nuveen, LLC | $1.3M | 863,035 | 0.00% | 6q | +1.9%+$24.1K |
| BANK OF AMERICA CORP /DE/ | $1.2M | 795,716 | 0.00% | 31q | -30.3%-$519.2K |
| Swiss National Bank | $1.1M | 761,455 | 0.00% | 31q | -10.0%-$126.5K |
| Invesco Ltd. | $1.0M | 685,076 | 0.00% | 31q | -13.6%-$162.1K |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $1.0M | 623,561 | 0.00% | 31q | +59.3%+$381.3K |
| PFG Investments, LLC | $915.7K | 610,491 | 0.04% | 10q | -45.1%-$753.4K |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | $861.2K | 574,107 | 0.00% | 31q | -14.9%-$151.1K |
| Assenagon Asset Management S.A. | $851.0K | 570,678 | 0.00% | 14q | -12.5%-$121.4K |
| Kovack Advisors, Inc. | $804.3K | 536,202 | 0.04% | 2q | +16.6%+$114.8K |
| RHUMBLINE ADVISERS | $748.3K | 498,861 | 0.00% | 31q | HELD |
| VAN ECK ASSOCIATES CORP | $658.0K | 438,645 | 0.00% | 17q | +174.0%+$417.8K |
| COMMONWEALTH EQUITY SERVICES, LLC | $647.8K | 431,894 | 0.00% | 31q | HELD |
| Connor, Clark & Lunn Investment Management Ltd. | $618.1K | 412,051 | 0.00% | 7q | -21.2%-$166.3K |
| DEUTSCHE BANK AG\ | $597.9K | 398,603 | 0.00% | 34q | +7.5%+$41.5K |
| ALGERT GLOBAL LLC | $595.5K | 397,030 | 0.01% | new | NEW |
| WELLS FARGO & COMPANY/MN | $531.1K | 354,039 | 0.00% | 31q | +8.9%+$43.2K |
| Legal & General Group Plc | $520.2K | 346,787 | 0.00% | 31q | +1.0%+$5.0K |
| ALLIANCEBERNSTEIN L.P. | $504.7K | 442,680 | 0.00% | 31q | +4.6%+$22.2K |
| VANGUARD ASSET MANAGEMENT, Ltd | $441.0K | 294,013 | 0.00% | 2q | HELD |
| ROYAL BANK OF CANADA | $435.0K | 289,812 | 0.00% | 31q | +31.7%+$104.8K |
| XTX Topco Ltd | $429.3K | 286,173 | 0.01% | 3q | -33.6%-$217.2K |
| JANE STREET GROUP, LLC | $382.4K | 229,454 | 0.00% | 31q | -79.4%-$1.5M |
| Creative Planning | $369.1K | 246,065 | 0.00% | 31q | +39.0%+$103.6K |
| TUDOR INVESTMENT CORP ET AL | $367.2K | 244,821 | 0.00% | 18q | HELD |
| MetLife Investment Management, LLC | $340.2K | 226,799 | 0.00% | 32q | +10.8%+$33.1K |
| Russell Investments Group, Ltd. | $323.7K | 215,820 | 0.00% | 10q | +578.3%+$276.0K |
| Jupiter Topco LLC | $310.5K | 206,314 | 0.00% | new | FIRST |
| CITIGROUP INC | $299.7K | 199,824 | 0.00% | 31q | +493.4%+$249.2K |
| HSBC HOLDINGS PLC | $298.9K | 199,966 | 0.00% | 2q | -16.1%-$57.3K |
| SIMPLEX TRADING, LLC | $288.5K | 23,233 | 0.00% | 21q | +217.4%+$197.6K |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | $278.3K | 185,564 | 0.00% | 9q | -6.2%-$18.5K |
| Vanguard Global Advisers, LLC | $272.6K | 181,766 | 0.00% | 2q | HELD |
| RPg Family Wealth Advisory, LLC | $265.9K | 177,238 | 0.02% | 4q | +100.0%+$132.9K |
| STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM | $264.4K | 176,260 | 0.00% | 31q | HELD |
| TWO SIGMA INVESTMENTS, LP | $263.7K | 175,801 | 0.00% | 17q | +3.4%+$8.7K |
| GAMCO INVESTORS, INC. ET AL | $262.5K | 175,000 | 0.00% | 31q | HELD |
| FIFTH THIRD BANCORP | $255.0K | 170,000 | 0.00% | 2q | +32.0%+$61.8K |
| GABELLI FUNDS LLC | $255.0K | 170,000 | 0.00% | 31q | HELD |
| JPMORGAN CHASE & CO | $254.1K | 168,305 | 0.00% | 31q | -66.9%-$513.7K |
| IEQ CAPITAL, LLC | $254.1K | 169,425 | 0.00% | 7q | +81.7%+$114.3K |
| MERCER GLOBAL ADVISORS INC /ADV | $230.4K | 153,616 | 0.00% | 24q | +190.8%+$151.2K |
| 360 Financial, Inc. | $225.4K | 150,300 | 0.06% | 27q | +54.5%+$79.5K |
| Point72 Asset Management, L.P. | $217.9K | 145,234 | 0.00% | 2q | +55.6%+$77.8K |
| Teton Advisors, LLC | $210.0K | 140,000 | 0.12% | 4q | HELD |
| IMC-Chicago, LLC | $205.3K | options only | 0.00% | 2q | OPTIONS |
| Police & Firemen's Retirement System of New Jersey | $198.7K | 132,463 | 0.00% | 7q | +29.4%+$45.1K |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | $178.7K | 119,132 | 0.00% | 31q | -2.5%-$4.5K |
| HIGHLINE WEALTH PARTNERS LLC | $175.0K | 116,680 | 0.04% | 16q | HELD |
| State of Wyoming | $174.7K | 116,489 | 0.02% | 2q | -30.3%-$75.8K |
| NEW YORK STATE COMMON RETIREMENT FUND | $171.5K | 114,301 | 0.00% | 31q | HELD |
| GLENMEDE TRUST CO NA | $169.1K | 112,750 | 0.00% | 3q | HELD |
| Vanguard Investments Australia, Ltd. | $166.4K | 110,958 | 0.00% | 2q | HELD |
| Headlands Technologies LLC | $162.0K | 107,989 | 0.02% | 6q | +91.2%+$77.3K |
| ARIZONA STATE RETIREMENT SYSTEM | $157.1K | 104,725 | 0.00% | 26q | -9.7%-$16.9K |
| ZAZOVE ASSOCIATES LLC | $150.0K | 100,000 | 0.01% | 6q | -33.3%-$75.0K |
| BARCLAYS PLC | $149.4K | 99,596 | 0.00% | 31q | -28.0%-$58.1K |
| GROUP ONE TRADING LLC | $148.4K | 50,547 | 0.00% | 2q | +24.3%+$29.0K |
| AMERIPRISE FINANCIAL INC | $141.1K | 94,061 | 0.00% | 31q | -51.4%-$149.1K |
| Arax Advisory Partners | $140.4K | 93,616 | 0.00% | 2q | +31850.9%+$140.0K |
| Cerity Partners LLC | $136.7K | 91,099 | 0.00% | 4q | +288.1%+$101.4K |
| KLP KAPITALFORVALTNING AS | $136.1K | 90,700 | 0.00% | 7q | HELD |
| INTECH INVESTMENT MANAGEMENT LLC | $128.8K | 85,883 | 0.00% | 8q | -31.7%-$59.9K |
| Allied Private Wealth LLC | $128.5K | 91,137 | 0.08% | new | FIRST |
| WEALTH ENHANCEMENT ADVISORY SERVICES, LLC | $113.4K | 83,994 | 0.00% | 9q | +34.7%+$29.2K |
| MILLENNIUM MANAGEMENT LLC | $108.5K | 72,301 | 0.00% | new | NEW |
| OSAIC HOLDINGS, INC. | $104.3K | 69,567 | 0.00% | 26q | +45.9%+$32.8K |
| PRUDENTIAL FINANCIAL INC | $103.5K | 68,976 | 0.00% | 31q | +5.2%+$5.1K |
| Cascade Financial Partners, LLC | $99.7K | 66,490 | 0.01% | 10q | HELD |
| Pictet Asset Management Holding SA | $98.2K | 65,495 | 0.00% | 12q | HELD |
| CAPTRUST FINANCIAL ADVISORS | $95.6K | 63,704 | 0.00% | 14q | +58.1%+$35.1K |
| Cetera Investment Advisers | $91.4K | 60,947 | 0.00% | 23q | +2.7%+$2.4K |
| KESTRA PRIVATE WEALTH SERVICES, LLC | $87.7K | 58,450 | 0.00% | 14q | HELD |
| BNP PARIBAS FINANCIAL MARKETS | $86.3K | 57,528 | 0.00% | 31q | -35.9%-$48.3K |
| Private Advisor Group, LLC | $83.0K | 55,301 | 0.00% | 15q | HELD |
| Zurcher Kantonalbank (Zurich Cantonalbank) | $82.7K | 55,140 | 0.00% | 31q | HELD |
Five percent filings
Anyone crossing 5% of a company must say so within days - far sooner than the next quarterly holdings report. A 13D declares an intent to influence the company; a 13G is the passive version. See all activist filings →
| Filed | Form | Filer | % of class |
|---|---|---|---|
| 2026-07-01 | 13D/A | FROST PHILLIP MD ET AL INDIVIDUALwith 2 co-filers | 34.1% |
Quarter by quarter
Coverage begins with the quarter ending 2018-12-31. Earlier filings exist only as occasional late amendments, too sparse to describe a market, so they are not shown.
| Quarter | Holders | Value | Shares | New | Added | Trimmed | Options |
|---|---|---|---|---|---|---|---|
| Q2 2026 | 221 | $307.8M | 204,720,611 | 25 | 69 | 47 | 0.3% |
| Q1 2026 | 223 | $228.1M | 199,471,281 | 38 | 49 | 59 | 0.3% |
| Q4 2025 | 207 | $250.3M | 196,886,211 | 20 | 35 | 73 | 0.9% |
| Q3 2025 | 220 | $305.9M | 194,836,543 | 26 | 70 | 48 | 1.3% |
| Q2 2025 | 205 | $270.2M | 202,022,065 | 12 | 46 | 60 | 1.3% |
| Q1 2025 | 234 | $393.8M | 234,275,472 | 39 | 59 | 51 | 1.2% |
| Q4 2024 | 219 | $307.2M | 191,464,762 | 21 | 58 | 49 | 8.4% |
| Q3 2024 | 217 | $314.0M | 184,997,500 | 29 | 44 | 57 | 12.2% |
| Q2 2024 | 215 | $253.7M | 180,379,200 | 36 | 36 | 62 | 11.1% |
| Q1 2024 | 200 | $271.7M | 157,512,140 | 38 | 42 | 55 | 30.3% |
| Q4 2023 | 191 | $262.4M | 170,305,062 | 18 | 46 | 50 | 2.0% |
| Q3 2023 | 203 | $267.7M | 164,183,983 | 21 | 43 | 57 | 1.9% |
| Q2 2023 | 207 | $375.4M | 170,482,486 | 28 | 48 | 45 | 1.7% |
| Q1 2023 | 195 | $240.7M | 163,079,063 | 28 | 49 | 46 | 1.2% |
| Q4 2022 | 180 | $191.5M | 149,147,885 | 24 | 53 | 41 | 2.7% |
| Q3 2022 | 211 | $366.2M | 185,337,017 | 19 | 64 | 53 | 4.3% |
| Q2 2022 | 219 | $502.1M | 189,946,121 | 29 | 55 | 68 | 4.3% |
| Q1 2022 | 225 | $703.7M | 195,416,737 | 30 | 46 | 71 | 4.4% |
| Q4 2021 | 234 | $1.0B | 194,641,092 | 37 | 53 | 60 | 10.2% |
| Q3 2021 | 207 | $708.3M | 183,229,583 | 15 | 50 | 56 | 5.6% |
| Q2 2021 | 236 | $814.7M | 191,268,721 | 30 | 55 | 69 | 4.9% |
| Q1 2021 | 241 | $852.1M | 190,507,836 | 39 | 78 | 63 | 4.1% |
| Q4 2020 | 240 | $823.2M | 190,756,737 | 47 | 58 | 69 | 8.5% |
| Q3 2020 | 214 | $761.6M | 195,514,416 | 38 | 70 | 58 | 5.3% |
| Q2 2020 | 209 | $709.9M | 200,565,144 | 52 | 55 | 44 | 3.7% |
| Q1 2020 | 178 | $225.7M | 161,869,455 | 21 | 49 | 51 | 3.9% |
| Q4 2019 | 193 | $278.5M | 182,273,664 | 28 | 64 | 50 | 3.8% |
| Q3 2019 | 179 | $320.6M | 147,511,177 | 15 | 53 | 51 | 3.8% |
| Q2 2019 | 192 | $406.2M | 156,758,889 | 24 | 53 | 56 | 5.9% |
| Q1 2019 | 194 | $441.4M | 161,120,958 | 28 | 62 | 48 | 4.8% |
| Q4 2018 | 197 | $478.3M | 146,574,561 | 4 | 2 | 4 | 8.0% |