MADRIGAL PHARMACEUTICALS INC (MDGL)
Institutional ownership reported to the SEC as of Q2 2026, across 31 quarters.
392
Reporting holders
$13.2B
Reported value
100.7%
Of shares outstanding
5.4%
Held as options
+30
Holder change
Institutions report 23,264,858 shares against 23,104,126 outstanding. Shares only - option lines are excluded, which is why this can be compared with the company at all. The count comes from the cover page of the company's own most recent report, so it is dated when that was filed rather than at quarter end. Over 100% because an adviser and a sub-adviser can both report the same shares, and both are counted.
Options share is the part of reported value carried in derivative lines rather than shares. A high figure means institutions are expressing a view on this security without owning much of it.
Holders
| Filer | Value | Shares | Their book | Held | Change |
|---|---|---|---|---|---|
| BAKER BROS. ADVISORS LP | $1.2B | 2,143,131 | 5.77% | 31q | HELD |
| RTW INVESTMENTS, LP | $1.1B | 1,993,687 | 9.14% | 13q | HELD |
| Jupiter Topco LLC | $1.0B | 1,936,099 | 0.42% | new | FIRST |
| Avoro Capital Advisors LLC | $984.4M | 1,833,333 | 8.84% | 31q | +0.8%+$8.1M |
| PAULSON & CO. INC. | $719.5M | 1,340,020 | 27.94% | 13q | -3.7%-$28.0M |
| BlackRock, Inc. | $644.8M | 1,200,770 | 0.01% | 8q | -23.0%-$192.9M |
| VANGUARD CAPITAL MANAGEMENT LLC | $448.7M | 835,668 | 0.01% | 2q | +1.0%+$4.6M |
| WELLINGTON MANAGEMENT GROUP LLP | $443.4M | 825,714 | 0.08% | 8q | +18.8%+$70.2M |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $419.8M | 781,731 | 0.02% | 2q | -7.1%-$31.9M |
| CITADEL ADVISORS LLC | $369.5M | 507,233 | 0.04% | 31q | +11.8%+$38.9M |
| STATE STREET CORP | $283.0M | 527,057 | 0.01% | 31q | -13.5%-$44.3M |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $240.0M | 148,610 | 0.02% | 31q | +568.9%+$204.1M |
| UBS Group AG | $215.7M | 401,708 | 0.03% | 31q | +241.1%+$152.5M |
| GEODE CAPITAL MANAGEMENT, LLC | $201.3M | 374,880 | 0.01% | 31q | -17.8%-$43.5M |
| FMR LLC | $191.3M | 356,201 | 0.01% | 31q | -30.4%-$83.5M |
| JANE STREET GROUP, LLC | $190.5M | 191,541 | 0.02% | 15q | +434.5%+$154.9M |
| WILLIAM BLAIR INVESTMENT MANAGEMENT, LLC | $174.0M | 324,123 | 0.52% | 7q | -4.8%-$8.8M |
| Invesco Ltd. | $161.9M | 301,435 | 0.01% | 26q | -8.5%-$15.1M |
| ARMISTICE CAPITAL, LLC | $154.6M | 288,000 | 1.89% | 30q | +8.9%+$12.6M |
| Assenagon Asset Management S.A. | $133.4M | 248,428 | 0.08% | 3q | +1449.5%+$124.8M |
| GOLDMAN SACHS GROUP INC | $132.2M | 246,280 | 0.01% | 31q | -11.2%-$16.7M |
| Polar Capital Holdings Plc | $131.2M | 244,274 | 0.31% | 10q | -15.6%-$24.2M |
| AMERIPRISE FINANCIAL INC | $124.1M | 231,205 | 0.03% | 15q | +17.7%+$18.7M |
| NORGES BANK | $114.8M | 213,886 | 0.01% | 30q | +8.9%+$9.4M |
| Artisan Partners Limited Partnership | $112.9M | 210,205 | 0.18% | 24q | +14.5%+$14.3M |
| Pictet Asset Management Holding SA | $103.5M | 192,896 | 0.10% | 12q | +3.0%+$3.0M |
| ALLIANCEBERNSTEIN L.P. | $99.2M | 189,458 | 0.03% | 31q | +51.0%+$33.5M |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $99.0M | 184,324 | 0.01% | 31q | -14.9%-$17.4M |
| Sixth Street Partners Management Company, L.P. | $99.0M | 184,324 | 0.01% | new | NEW |
| Caption Management, LLC | $98.4M | options only | 0.46% | 2q | OPTIONS |
| TORONTO DOMINION BANK | $97.4M | 181,432 | 0.11% | 2q | +39.1%+$27.4M |
| Rock Springs Capital Management LP | $94.0M | 174,999 | 4.59% | 31q | +2.3%+$2.1M |
| Hood River Capital Management LLC | $90.8M | 169,084 | 0.66% | 7q | -32.2%-$43.2M |
| D. E. Shaw & Co., Inc. | $87.1M | 35,071 | 0.04% | 23q | +16.4%+$12.3M |
| Holocene Advisors, LP | $82.1M | 152,924 | 0.19% | new | NEW |
| Point72 Asset Management, L.P. | $76.6M | 137,029 | 0.08% | 6q | -39.2%-$49.5M |
| MORGAN STANLEY | $74.6M | 139,009 | 0.00% | 35q | -27.3%-$28.1M |
| BANK OF AMERICA CORP /DE/ | $72.0M | 134,036 | 0.00% | 31q | -29.3%-$29.8M |
| Bank of New York Mellon Corp | $69.0M | 128,520 | 0.01% | 31q | -5.4%-$4.0M |
| Woodline Partners LP | $67.6M | 125,899 | 0.21% | 10q | HELD |
| VANGUARD FIDUCIARY TRUST CO | $65.3M | 121,583 | 0.01% | 2q | -5.1%-$3.5M |
| MILLENNIUM MANAGEMENT LLC | $63.6M | 81,196 | 0.02% | 17q | +98.8%+$31.6M |
| Clearbridge Investments, LLC | $58.7M | 109,325 | 0.05% | 2q | +347.2%+$45.6M |
| Erste Asset Management GmbH | $58.1M | 110,210 | 0.45% | 15q | -31.2%-$26.4M |
| MARSHALL WACE, LLP | $54.7M | 101,859 | 0.04% | 9q | +365.1%+$42.9M |
| Fiera Capital Corp | $53.6M | 99,857 | 0.19% | 9q | -42.6%-$39.8M |
| AMERICAN CENTURY COMPANIES INC | $53.4M | 99,396 | 0.02% | 14q | -39.4%-$34.7M |
| NORTHERN TRUST CORP | $52.9M | 98,510 | 0.01% | 31q | -34.0%-$27.2M |
| NEW YORK STATE COMMON RETIREMENT FUND | $50.9M | 94,743 | 0.06% | 31q | +26.1%+$10.5M |
| WESTFIELD CAPITAL MANAGEMENT CO LP | $50.4M | 93,931 | 0.16% | 2q | -0.9%-$473.6K |
| 683 Capital Management, LLC | $48.3M | options only | 2.37% | 14q | OPTIONS |
| DEUTSCHE BANK AG\ | $45.1M | 83,916 | 0.01% | 34q | -14.4%-$7.6M |
| ALKEON CAPITAL MANAGEMENT LLC | $43.0M | 80,000 | 0.06% | 4q | HELD |
| Balyasny Asset Management L.P. | $42.4M | 79,011 | 0.05% | new | NEW |
| Driehaus Capital Management LLC | $41.9M | 78,094 | 0.24% | 4q | -29.6%-$17.6M |
| CITIGROUP INC | $39.3M | 37,255 | 0.01% | 31q | +45.6%+$12.3M |
| Candriam S.C.A. | $38.7M | 72,121 | 0.17% | 6q | -15.1%-$6.9M |
| GROUP ONE TRADING LLC | $37.1M | options only | 0.05% | 25q | OPTIONS |
| JPMORGAN CHASE & CO | $37.1M | 29,473 | 0.00% | new | NEW |
| Tri Locum Partners LP | $36.7M | 68,273 | 4.51% | 15q | -33.9%-$18.8M |
| Vestal Point Capital, LP | $34.9M | 65,000 | 0.82% | 2q | +106.6%+$18.0M |
| Allspring Global Investments Holdings, LLC | $34.8M | 67,668 | 0.05% | 3q | +5548.4%+$34.2M |
| IMC-Chicago, LLC | $33.7M | 10,847 | 0.01% | 3q | +39.2%+$9.5M |
| VOYA INVESTMENT MANAGEMENT LLC | $32.9M | 61,202 | 0.03% | 31q | +2.1%+$661.0K |
| BNP PARIBAS FINANCIAL MARKETS | $31.1M | 57,998 | 0.01% | 31q | +1.4%+$440.8K |
| Jones Hill Capital LP | $28.2M | 52,545 | 6.00% | new | NEW |
| EULAV Asset Management | $27.9M | 52,000 | 0.89% | 11q | +6.1%+$1.6M |
| SCHRODER INVESTMENT MANAGEMENT GROUP | $27.2M | 51,630 | 0.02% | 11q | +29.6%+$6.2M |
| Russell Investments Group, Ltd. | $26.5M | 49,294 | 0.02% | 10q | +10.8%+$2.6M |
| RENAISSANCE TECHNOLOGIES LLC | $24.7M | 45,942 | 0.03% | 8q | -36.1%-$13.9M |
| Affinity Asset Advisors, LLC | $21.5M | 40,000 | 0.97% | 19q | -27.3%-$8.1M |
| Mirae Asset Global Investments Co., Ltd. | $17.9M | 33,420 | 0.03% | 13q | -59.2%-$26.0M |
| Nuveen, LLC | $17.5M | 32,631 | 0.00% | 6q | -47.4%-$15.8M |
| SEGALL BRYANT & HAMILL, LLC | $17.4M | 32,444 | 0.21% | 4q | +1.8%+$308.2K |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | $17.4M | 32,403 | 0.00% | 14q | +36.2%+$4.6M |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | $17.2M | 31,998 | 0.02% | 5q | -2.7%-$473.1K |
| GROUPAMA ASSET MANAGMENT | $16.6M | 30,941 | 0.21% | 11q | -12.2%-$2.3M |
| Swiss National Bank | $16.1M | 29,940 | 0.01% | 31q | +2.5%+$386.6K |
| PFM Health Sciences, LP | $15.7M | 29,313 | 1.35% | 3q | -14.2%-$2.6M |
| CANADA PENSION PLAN INVESTMENT BOARD | $15.6M | 29,080 | 0.01% | 7q | +137.2%+$9.0M |
| Rockefeller Capital Management L.P. | $15.6M | 29,015 | 0.02% | 14q | -14.3%-$2.6M |
| GILDER GAGNON HOWE & CO LLC | $15.3M | 28,573 | 0.16% | 10q | -2.8%-$439.2K |
| SIMPLEX TRADING, LLC | $15.1M | options only | 0.01% | 2q | OPTIONS |
| WELLS FARGO & COMPANY/MN | $14.2M | 26,536 | 0.00% | 31q | -58.8%-$20.3M |
| SEI INVESTMENTS CO | $13.9M | 25,826 | 0.01% | 15q | +6.7%+$874.1K |
| Integral Health Asset Management, LLC | $13.4M | 25,000 | 0.53% | 2q | HELD |
| California Public Employees Retirement System | $13.0M | 24,277 | 0.01% | 14q | +4.7%+$579.4K |
| WCM INVESTMENT MANAGEMENT, LLC | $12.1M | 22,985 | 0.02% | 4q | -2.4%-$303.2K |
| Susquehanna Portfolio Strategies, LLC | $11.8M | 22,003 | 0.19% | 5q | +252.0%+$8.5M |
| Tao Capital Management LP | $11.3M | 21,000 | 0.58% | 24q | HELD |
| HSBC HOLDINGS PLC | $10.9M | 20,240 | 0.00% | 3q | +1738.3%+$10.3M |
| FIRST TRUST ADVISORS LP | $10.6M | 19,826 | 0.01% | 8q | -10.8%-$1.3M |
| Weiss Asset Management LP | $10.4M | 19,325 | 0.11% | new | NEW |
| RAYMOND JAMES FINANCIAL INC | $10.4M | 19,305 | 0.00% | 7q | -71.0%-$25.4M |
| ArrowMark Colorado Holdings LLC | $10.0M | 18,624 | 0.42% | 10q | -70.2%-$23.5M |
| RHUMBLINE ADVISERS | $9.7M | 18,154 | 0.01% | 31q | -16.6%-$1.9M |
| SPHERA FUNDS MANAGEMENT LTD. | $9.4M | 17,419 | 1.22% | 3q | +92.7%+$4.5M |
| AQR CAPITAL MANAGEMENT LLC | $8.5M | 15,827 | 0.00% | 15q | -0.8%-$67.7K |
| SILVERCREST ASSET MANAGEMENT GROUP LLC | $8.4M | 15,655 | 0.06% | 2q | -1.9%-$165.4K |
| VANGUARD ASSET MANAGEMENT, Ltd | $8.2M | 15,204 | 0.01% | 2q | +7.9%+$598.2K |
Five percent filings
Anyone crossing 5% of a company must say so within days - far sooner than the next quarterly holdings report. A 13D declares an intent to influence the company; a 13G is the passive version. See all activist filings →
| Filed | Form | Filer | % of class |
|---|---|---|---|
| 2026-07-29 | 13G/A | BlackRock, Inc. | 4.6% |
Quarter by quarter
Coverage begins with the quarter ending 2018-12-31. Earlier filings exist only as occasional late amendments, too sparse to describe a market, so they are not shown.
| Quarter | Holders | Value | Shares | New | Added | Trimmed | Options |
|---|---|---|---|---|---|---|---|
| Q2 2026 | 392 | $13.2B | 23,264,858 | 71 | 130 | 128 | 5.4% |
| Q1 2026 | 362 | $12.8B | 23,338,882 | 61 | 118 | 115 | 4.7% |
| Q4 2025 | 364 | $14.0B | 22,985,821 | 67 | 125 | 108 | 4.3% |
| Q3 2025 | 332 | $11.1B | 22,982,540 | 77 | 95 | 101 | 5.1% |
| Q2 2025 | 286 | $7.4B | 22,916,884 | 32 | 96 | 100 | 6.0% |
| Q1 2025 | 305 | $8.1B | 22,999,933 | 66 | 97 | 81 | 6.2% |
| Q4 2024 | 271 | $7.5B | 22,192,662 | 51 | 85 | 71 | 8.8% |
| Q3 2024 | 242 | $5.0B | 21,834,464 | 39 | 77 | 75 | 7.6% |
| Q2 2024 | 244 | $6.6B | 21,845,351 | 42 | 90 | 67 | 7.6% |
| Q1 2024 | 252 | $6.2B | 20,613,475 | 70 | 79 | 69 | 11.8% |
| Q4 2023 | 209 | $4.9B | 19,364,351 | 41 | 81 | 49 | 9.5% |
| Q3 2023 | 185 | $2.8B | 16,953,345 | 30 | 83 | 47 | 11.6% |
| Q2 2023 | 190 | $4.0B | 14,333,002 | 31 | 75 | 54 | 17.1% |
| Q1 2023 | 195 | $3.8B | 13,547,736 | 59 | 58 | 47 | 13.5% |
| Q4 2022 | 170 | $4.4B | 12,259,022 | 81 | 41 | 34 | 19.4% |
| Q3 2022 | 139 | $819.7M | 11,832,772 | 19 | 49 | 29 | 6.2% |
| Q2 2022 | 139 | $889.9M | 12,005,509 | 26 | 42 | 39 | 3.6% |
| Q1 2022 | 139 | $1.2B | 12,258,493 | 20 | 44 | 45 | 2.0% |
| Q4 2021 | 144 | $1.0B | 12,108,405 | 21 | 45 | 34 | 2.2% |
| Q3 2021 | 132 | $892.2M | 10,979,057 | 9 | 45 | 40 | 1.8% |
| Q2 2021 | 147 | $1.1B | 11,229,236 | 28 | 59 | 35 | 1.0% |
| Q1 2021 | 135 | $1.4B | 12,210,464 | 16 | 48 | 34 | 0.8% |
| Q4 2020 | 133 | $1.4B | 12,307,692 | 17 | 46 | 39 | 1.1% |
| Q3 2020 | 125 | $1.4B | 11,637,067 | 12 | 38 | 46 | 3.4% |
| Q2 2020 | 125 | $1.3B | 11,265,397 | 29 | 42 | 34 | 3.3% |
| Q1 2020 | 108 | $752.1M | 11,090,655 | 15 | 45 | 26 | 1.4% |
| Q4 2019 | 123 | $995.9M | 10,597,833 | 19 | 41 | 36 | 3.0% |
| Q3 2019 | 113 | $852.6M | 9,642,956 | 13 | 45 | 27 | 2.5% |
| Q2 2019 | 123 | $1.1B | 9,791,642 | 14 | 58 | 23 | 7.9% |
| Q1 2019 | 139 | $1.3B | 9,625,714 | 21 | 47 | 31 | 8.6% |
| Q4 2018 | 142 | $1.1B | 9,072,632 | 1 | 3 | 2 | 10.0% |