LYELL IMMUNOPHARMA INC (LYEL)
Institutional ownership reported to the SEC as of Q2 2026, across 15 quarters.
84
Reporting holders
$168.7M
Reported value
48.7%
Of shares outstanding
0.6%
Held as options
+11
Holder change
Institutions report 11,936,751 shares against 24,505,141 outstanding. Shares only - option lines are excluded, which is why this can be compared with the company at all. The count comes from the cover page of the company's own most recent report, so it is dated when that was filed rather than at quarter end.
Options share is the part of reported value carried in derivative lines rather than shares. A high figure means institutions are expressing a view on this security without owning much of it.
Holders
| Filer | Value | Shares | Their book | Held | Change |
|---|---|---|---|---|---|
| ARCH Venture Management, LLC | $45.5M | 3,247,162 | 4.14% | 5q | HELD |
| GSK plc | $21.3M | 1,512,659 | 3.53% | 3q | HELD |
| VANGUARD CAPITAL MANAGEMENT LLC | $11.1M | 786,774 | 0.00% | 2q | +9.6%+$964.1K |
| Orland Properties Ltd | $10.6M | 754,698 | 5.25% | 4q | HELD |
| BlackRock, Inc. | $10.2M | 724,342 | 0.00% | 5q | +277.6%+$7.5M |
| Almitas Capital LLC | $8.2M | 581,407 | 1.96% | 5q | +0.6%+$50.6K |
| Foresite Capital Management V, LLC | $6.7M | 476,386 | 1.85% | 5q | HELD |
| MILLENNIUM MANAGEMENT LLC | $5.2M | 367,473 | 0.00% | 5q | -19.9%-$1.3M |
| Opaleye Management Inc. | $4.8M | 344,025 | 0.44% | 2q | +334.9%+$3.7M |
| venBio Partners LLC | $4.7M | 337,697 | 0.91% | 5q | HELD |
| GEODE CAPITAL MANAGEMENT, LLC | $4.4M | 310,636 | 0.00% | 5q | +86.0%+$2.0M |
| Alphabet Inc. | $4.1M | 293,256 | 0.00% | 5q | HELD |
| STATE STREET CORP | $2.6M | 185,322 | 0.00% | 5q | +155.5%+$1.6M |
| HSG Holding Ltd | $2.1M | 152,299 | 0.18% | 5q | HELD |
| RENAISSANCE TECHNOLOGIES LLC | $1.8M | 130,190 | 0.00% | 5q | +11.8%+$193.6K |
| NORTHERN TRUST CORP | $1.7M | 118,500 | 0.00% | 5q | +291.3%+$1.2M |
| Qube Research & Technologies Ltd | $1.6M | 110,531 | 0.00% | 3q | +100.6%+$778.7K |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $1.5M | 107,570 | 0.00% | 5q | +25.1%+$303.5K |
| Sixth Street Partners Management Company, L.P. | $1.5M | 107,570 | 0.00% | new | NEW |
| MARSHALL WACE, LLP | $1.5M | 106,300 | 0.00% | 3q | -28.4%-$593.1K |
| Velan Capital Investment Management LP | $1.5M | 105,000 | 0.90% | 2q | +2.9%+$42.1K |
| VANGUARD FIDUCIARY TRUST CO | $1.3M | 93,095 | 0.00% | 2q | +7.1%+$86.7K |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $1.3M | 91,891 | 0.00% | 2q | +299.3%+$967.7K |
| MIC Capital Management UK LLP | $1.2M | 87,028 | 0.31% | 5q | HELD |
| GOLDMAN SACHS GROUP INC | $1.2M | 86,779 | 0.00% | 3q | -24.2%-$389.4K |
| DIMENSIONAL FUND ADVISORS LP | $957.1K | 68,315 | 0.00% | 2q | +42.7%+$286.2K |
| CITADEL ADVISORS LLC | $753.0K | 18,695 | 0.00% | 5q | -95.1%-$14.6M |
| TWO SIGMA INVESTMENTS, LP | $743.6K | 52,927 | 0.00% | 5q | +356.9%+$580.9K |
| JANE STREET GROUP, LLC | $646.5K | 46,011 | 0.00% | 3q | -28.0%-$251.2K |
| Squarepoint Ops LLC | $594.6K | 42,322 | 0.00% | 2q | +119.4%+$323.5K |
| Ikarian Capital, LLC | $577.2K | 41,081 | 0.06% | 5q | HELD |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $563.4K | options only | 0.00% | 5q | OPTIONS |
| MORGAN STANLEY | $520.6K | 37,050 | 0.00% | 5q | -34.0%-$268.4K |
| CANADA PENSION PLAN INVESTMENT BOARD | $413.2K | 29,411 | 0.00% | 5q | HELD |
| Point72 Asset Management, L.P. | $366.4K | 26,080 | 0.00% | 3q | +22.5%+$67.3K |
| UBS Group AG | $365.0K | 25,982 | 0.00% | 5q | -18.3%-$81.9K |
| Bank of New York Mellon Corp | $346.7K | 24,673 | 0.00% | new | NEW |
| AMERICAN CENTURY COMPANIES INC | $344.8K | 24,540 | 0.00% | 2q | +53.7%+$120.4K |
| Jump Financial, LLC | $308.5K | 21,956 | 0.00% | 2q | +9.1%+$25.8K |
| Clearstead Advisors, LLC | $280.4K | 19,958 | 0.00% | 2q | -50.0%-$280.4K |
| EntryPoint Capital, LLC | $272.7K | 19,410 | 0.07% | new | NEW |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | $252.9K | 18,000 | 0.00% | 5q | HELD |
| Susquehanna Portfolio Strategies, LLC | $251.1K | 17,875 | 0.00% | 5q | -14.1%-$41.1K |
| Allspring Global Investments Holdings, LLC | $226.8K | 16,145 | 0.00% | new | NEW |
| RHUMBLINE ADVISERS | $217.2K | 15,462 | 0.00% | new | NEW |
| Invesco Ltd. | $195.5K | 13,914 | 0.00% | new | NEW |
| Nuveen, LLC | $177.0K | 12,595 | 0.00% | new | NEW |
| Graham Capital Management, L.P. | $163.0K | 11,602 | 0.00% | new | NEW |
| Brevan Howard Capital Management LP | $162.4K | 11,557 | 0.00% | 2q | -14.0%-$26.4K |
| BANK OF AMERICA CORP /DE/ | $152.7K | 10,871 | 0.00% | 5q | -67.4%-$315.4K |
| Walleye Capital LLC | $146.8K | 10,451 | 0.00% | 2q | -52.9%-$165.2K |
| LOS ANGELES CAPITAL MANAGEMENT LLC | $133.5K | 9,505 | 0.00% | new | NEW |
| DEUTSCHE BANK AG\ | $129.1K | 9,188 | 0.00% | new | NEW |
| WELLS FARGO & COMPANY/MN | $112.5K | 8,005 | 0.00% | 3q | +3102.0%+$109.0K |
| BNP PARIBAS FINANCIAL MARKETS | $110.2K | 7,845 | 0.00% | 5q | +274.1%+$80.8K |
| Vanguard Global Advisers, LLC | $72.6K | 5,165 | 0.00% | 2q | HELD |
| CITIGROUP INC | $70.6K | 5,025 | 0.00% | 5q | -15.0%-$12.5K |
| BARCLAYS PLC | $66.2K | 4,715 | 0.00% | 5q | +182.2%+$42.8K |
| JPMORGAN CHASE & CO | $61.1K | 4,796 | 0.00% | 5q | +226.7%+$42.4K |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | $60.9K | 4,333 | 0.00% | new | NEW |
| NEW YORK STATE COMMON RETIREMENT FUND | $57.6K | 4,100 | 0.00% | new | NEW |
| China Universal Asset Management Co., Ltd. | $52.2K | 3,714 | 0.00% | 5q | -1.5% |
| Police & Firemen's Retirement System of New Jersey | $48.4K | 3,446 | 0.00% | new | NEW |
| FMR LLC | $30.2K | 2,151 | 0.00% | 5q | +18.0%+$4.6K |
| Tower Research Capital LLC (TRC) | $19.2K | 1,364 | 0.00% | 5q | +4.8% |
| Mirae Asset Global Investments Co., Ltd. | $14.7K | 1,044 | 0.00% | 5q | -52.9%-$16.5K |
| Legal & General Group Plc | $12.9K | 917 | 0.00% | new | NEW |
| Zurcher Kantonalbank (Zurich Cantonalbank) | $12.7K | 905 | 0.00% | 2q | +102.5%+$6.4K |
| Ameritas Investment Partners, Inc. | $12.0K | 854 | 0.00% | new | NEW |
| JONES FINANCIAL COMPANIES LLLP | $11.9K | 1,025 | 0.00% | 5q | HELD |
| SIMPLEX TRADING, LLC | $11.6K | 226 | 0.00% | 5q | -67.4%-$24.0K |
| Russell Investments Group, Ltd. | $10.6K | 752 | 0.00% | new | NEW |
| ROYAL BANK OF CANADA | $10.0K | 742 | 0.00% | 4q | +195.6%+$6.6K |
| GF FUND MANAGEMENT CO. LTD. | $6.4K | 452 | 0.00% | 4q | -3.8% |
| Truvestments Capital LLC | $4.2K | 300 | 0.00% | new | NEW |
| Sterling Capital Management LLC | $2.7K | 190 | 0.00% | new | NEW |
| GROUP ONE TRADING LLC | $2.6K | 88 | 0.00% | 5q | -12.0% |
| Quarry LP | $2.5K | 179 | 0.00% | new | NEW |
| Caitong International Asset Management Co., Ltd | $955 | 68 | 0.00% | new | NEW |
| ACADIAN ASSET MANAGEMENT LLC | $836 | 59,748 | 0.00% | new | NEW |
| US BANCORP \DE\ | $815 | 58 | 0.00% | 5q | HELD |
| Cornerstone Financial Management LLC | $646 | 46 | 0.00% | 3q | HELD |
| HRT FINANCIAL LP | $513 | 36,575 | 0.00% | new | NEW |
| GAMMA Investing LLC | $492 | 35 | 0.00% | 5q | HELD |
| PRICE T ROWE ASSOCIATES INC /MD/ | $431 | 30,657 | 0.00% | 5q | +133.5% |
| GSA CAPITAL PARTNERS LLP | $368 | 26,225 | 0.02% | new | NEW |
| NISA INVESTMENT ADVISORS, LLC | $351 | 25 | 0.00% | 5q | HELD |
| Optiver Holding B.V. | $281 | 20 | 0.00% | new | NEW |
Five percent filings
Anyone crossing 5% of a company must say so within days - far sooner than the next quarterly holdings report. A 13D declares an intent to influence the company; a 13G is the passive version. See all activist filings →
| Filed | Form | Filer | % of class |
|---|---|---|---|
| 2026-08-14 | 13G/A | James B. Tananbaum INDIVIDUALwith 6 co-filers | 2.7% |
Quarter by quarter
Coverage begins with the quarter ending 2018-12-31. Earlier filings exist only as occasional late amendments, too sparse to describe a market, so they are not shown.
| Quarter | Holders | Value | Shares | New | Added | Trimmed | Options |
|---|---|---|---|---|---|---|---|
| Q2 2026 | 84 | $168.7M | 11,936,751 | 22 | 27 | 19 | 0.6% |
| Q1 2026 | 73 | $237.4M | 11,810,351 | 15 | 25 | 8 | 0.2% |
| Q4 2025 | 66 | $353.3M | 11,465,829 | 14 | 19 | 14 | 0.3% |
| Q3 2025 | 53 | $163.7M | 10,051,301 | 8 | 17 | 11 | 0.3% |
| Q2 2025 | 60 | $57.7M | 6,484,261 | 61 | 0 | 0 | 0.6% |
| Q4 2024 | 2 | $1.9K | 0 | 0 | 0 | 0 | 100.0% |
| Q3 2024 | 2 | $4.2K | 0 | 1 | 0 | 0 | 100.0% |
| Q2 2024 | 2 | $12.9K | 0 | 0 | 0 | 0 | 100.0% |
| Q1 2024 | 2 | $462 | 0 | 3 | 0 | 0 | 100.0% |
| Q3 2023 | 1 | $1 | 0 | 1 | 0 | 0 | 100.0% |
| Q4 2022 | 2 | $35.1K | 0 | 2 | 0 | 0 | 100.0% |
| Q3 2022 | 1 | $15.0K | 0 | 0 | 0 | 0 | 100.0% |
| Q2 2022 | 2 | $57.0K | 0 | 1 | 0 | 0 | 100.0% |
| Q1 2022 | 1 | $46.0K | 0 | 1 | 0 | 0 | 100.0% |
| Q4 2021 | 1 | $30.0K | 0 | 1 | 0 | 0 | 100.0% |