KRYSTAL BIOTECH INC (KRYS)
Institutional ownership reported to the SEC as of Q2 2026, across 31 quarters.
400
Reporting holders
$11.0B
Reported value
97.8%
Of shares outstanding
1.9%
Held as options
+56
Holder change
Institutions report 28,943,716 shares against 29,598,836 outstanding. Shares only - option lines are excluded, which is why this can be compared with the company at all. The count comes from the cover page of the company's own most recent report, so it is dated when that was filed rather than at quarter end. A figure this high can overstate: where an adviser and a sub-adviser both report the same shares, both are counted.
Options share is the part of reported value carried in derivative lines rather than shares. A high figure means institutions are expressing a view on this security without owning much of it.
Holders
| Filer | Value | Shares | Their book | Held | Change |
|---|---|---|---|---|---|
| FMR LLC | $1.6B | 4,418,197 | 0.07% | 31q | +1.0%+$16.4M |
| BlackRock, Inc. | $1.6B | 4,181,432 | 0.02% | 8q | +6.1%+$89.6M |
| Avoro Capital Advisors LLC | $1.1B | 2,888,888 | 9.64% | 19q | HELD |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $585.3M | 1,574,905 | 0.03% | 2q | +8.1%+$43.9M |
| STATE STREET CORP | $502.2M | 1,351,158 | 0.01% | 30q | +2.8%+$13.6M |
| VANGUARD CAPITAL MANAGEMENT LLC | $461.1M | 1,240,567 | 0.01% | 2q | +6.5%+$28.0M |
| Soleus Capital Management, L.P. | $349.1M | 939,254 | 12.03% | 23q | -18.5%-$79.5M |
| Capital World Investors | $289.1M | 777,843 | 0.03% | 10q | -5.7%-$17.4M |
| GEODE CAPITAL MANAGEMENT, LLC | $259.8M | 698,993 | 0.01% | 31q | +8.5%+$20.5M |
| Hood River Capital Management LLC | $246.6M | 663,375 | 1.79% | 25q | +7.1%+$16.3M |
| Redmile Group, LLC | $234.9M | 632,005 | 15.77% | 31q | -6.2%-$15.4M |
| WILLIAM BLAIR INVESTMENT MANAGEMENT, LLC | $211.9M | 570,153 | 0.64% | 5q | +40.0%+$60.6M |
| Frazier Life Sciences Management, L.P. | $178.9M | 481,307 | 3.90% | 18q | HELD |
| DIMENSIONAL FUND ADVISORS LP | $176.9M | 476,038 | 0.03% | 25q | +1.5%+$2.6M |
| FIRST TRUST ADVISORS LP | $120.8M | 324,900 | 0.07% | 8q | -7.3%-$9.5M |
| Invesco Ltd. | $120.7M | 324,755 | 0.01% | 22q | +29.2%+$27.3M |
| GOLDMAN SACHS GROUP INC | $111.1M | 298,841 | 0.01% | 27q | +39.0%+$31.2M |
| NORTHERN TRUST CORP | $105.5M | 283,784 | 0.01% | 31q | +12.4%+$11.6M |
| FRANKLIN RESOURCES INC | $97.3M | 261,917 | 0.02% | 18q | +46.1%+$30.7M |
| NORGES BANK | $96.3M | 259,030 | 0.01% | 14q | -9.0%-$9.5M |
| Jupiter Topco LLC | $95.4M | 256,665 | 0.04% | new | FIRST |
| BANK OF AMERICA CORP /DE/ | $95.3M | 256,431 | 0.01% | 31q | -1.6%-$1.6M |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $94.7M | 254,828 | 0.01% | 29q | +5.3%+$4.8M |
| Sixth Street Partners Management Company, L.P. | $94.7M | 254,828 | 0.01% | new | NEW |
| MORGAN STANLEY | $87.5M | 235,491 | 0.00% | 33q | +12.6%+$9.8M |
| Public Sector Pension Investment Board | $78.4M | 211,030 | 0.10% | 9q | +128.7%+$44.1M |
| VANGUARD FIDUCIARY TRUST CO | $70.4M | 189,528 | 0.02% | 2q | +5.8%+$3.9M |
| Nantahala Capital Management, LLC | $63.2M | options only | 1.05% | new | OPTIONS |
| PRINCIPAL FINANCIAL GROUP INC | $63.0M | 169,550 | 0.03% | 17q | +4.6%+$2.8M |
| Bank of New York Mellon Corp | $60.8M | 163,610 | 0.01% | 31q | +9.6%+$5.3M |
| UBS Group AG | $60.2M | 148,316 | 0.01% | 11q | +3.3%+$1.9M |
| RAYMOND JAMES FINANCIAL INC | $59.0M | 158,675 | 0.02% | 7q | +1.7%+$970.4K |
| Woodline Partners LP | $56.0M | 150,616 | 0.17% | 13q | HELD |
| Nuveen, LLC | $54.5M | 146,520 | 0.01% | 6q | +2.2%+$1.2M |
| Caption Management, LLC | $48.5M | options only | 0.23% | 13q | OPTIONS |
| BRAIDWELL LP | $47.9M | 128,975 | 1.77% | 15q | -29.3%-$19.9M |
| VOYA INVESTMENT MANAGEMENT LLC | $46.3M | 124,442 | 0.04% | 28q | +14.8%+$6.0M |
| TimesSquare Capital Management, LLC | $41.5M | 111,545 | 0.61% | 12q | -0.7%-$296.2K |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $40.8M | 1,899 | 0.00% | 26q | -79.0%-$153.5M |
| Pictet Asset Management Holding SA | $40.1M | 107,798 | 0.04% | 12q | -2.6%-$1.1M |
| 1832 Asset Management L.P. | $36.9M | 99,300 | 0.02% | 3q | +133.1%+$21.1M |
| WESTFIELD CAPITAL MANAGEMENT CO LP | $36.7M | 98,707 | 0.12% | new | NEW |
| BNP PARIBAS FINANCIAL MARKETS | $34.3M | 92,234 | 0.01% | 29q | -0.9%-$296.2K |
| JPMORGAN CHASE & CO | $33.5M | 87,342 | 0.00% | 31q | -11.9%-$4.5M |
| ORBIMED ADVISORS LLC | $30.9M | 83,200 | 0.57% | 11q | +20.4%+$5.2M |
| S SQUARED TECHNOLOGY, LLC | $28.8M | 77,545 | 8.94% | 31q | -10.1%-$3.2M |
| Bellevue Group AG | $28.8M | 77,530 | 0.61% | 19q | -83.9%-$150.2M |
| Biondo Investment Advisors, LLC | $26.4M | 70,945 | 3.23% | 5q | -1.5%-$408.8K |
| SEGALL BRYANT & HAMILL, LLC | $24.2M | 65,211 | 0.29% | 9q | -18.0%-$5.3M |
| Corient Private Wealth LP | $24.2M | 65,160 | 0.02% | 10q | +1749.6%+$22.9M |
| RHUMBLINE ADVISERS | $22.8M | 61,236 | 0.02% | 29q | -10.1%-$2.6M |
| RENAISSANCE TECHNOLOGIES LLC | $22.2M | 59,680 | 0.03% | 3q | +521.7%+$18.6M |
| Legal & General Group Plc | $21.8M | 58,580 | 0.00% | 29q | -0.8%-$174.7K |
| CITIGROUP INC | $20.8M | 56,016 | 0.01% | 31q | +79.7%+$9.2M |
| Bridgewater Associates, LP | $20.3M | 54,489 | 0.08% | 4q | +17.5%+$3.0M |
| SEI INVESTMENTS CO | $20.1M | 54,040 | 0.02% | 29q | +16.0%+$2.8M |
| Russell Investments Group, Ltd. | $19.6M | 52,621 | 0.02% | 14q | +100.8%+$9.8M |
| Allspring Global Investments Holdings, LLC | $19.5M | 52,407 | 0.03% | 19q | +2017.5%+$18.6M |
| NEUBERGER BERMAN GROUP LLC | $19.3M | 51,876 | 0.01% | 3q | +56.8%+$7.0M |
| AMERIPRISE FINANCIAL INC | $18.1M | 48,790 | 0.00% | 12q | -51.1%-$18.9M |
| Palisades Investment Partners, LLC | $17.8M | 47,801 | 5.05% | 9q | +5.3%+$890.5K |
| ACT CAPITAL MANAGEMENT, LLC | $16.7M | 45,000 | 10.93% | 9q | -25.6%-$5.8M |
| VICTORY CAPITAL MANAGEMENT INC | $16.7M | 44,935 | 0.01% | 17q | +10.4%+$1.6M |
| FEDERATED HERMES, INC. | $16.3M | 43,848 | 0.02% | 8q | +23.5%+$3.1M |
| CITADEL ADVISORS LLC | $16.0M | 2,725 | 0.00% | 31q | HELD |
| Swiss National Bank | $15.4M | 41,360 | 0.01% | 29q | -3.8%-$609.5K |
| GILDER GAGNON HOWE & CO LLC | $15.0M | 40,296 | 0.15% | 2q | HELD |
| CONGRESS ASSET MANAGEMENT CO | $14.9M | 40,134 | 0.09% | new | NEW |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | $14.4M | 38,697 | 0.00% | 27q | +4.8%+$654.1K |
| SEB Asset Management AB | $14.0M | 37,731 | 0.05% | 2q | -18.6%-$3.2M |
| WELLINGTON MANAGEMENT GROUP LLP | $13.7M | 36,936 | 0.00% | 10q | +261.2%+$9.9M |
| Life Cycle Investment Partners Ltd | $13.1M | 35,124 | 0.06% | new | NEW |
| WELLS FARGO & COMPANY/MN | $12.8M | 34,502 | 0.00% | 31q | +15.1%+$1.7M |
| NEW YORK STATE COMMON RETIREMENT FUND | $12.6M | 34,033 | 0.02% | 31q | +8.6%+$1.0M |
| Granite Investment Partners, LLC | $12.2M | 32,837 | 0.63% | 3q | +35.2%+$3.2M |
| PRUDENTIAL FINANCIAL INC | $12.1M | 32,662 | 0.01% | 13q | +10.2%+$1.1M |
| MUTUAL OF AMERICA CAPITAL MANAGEMENT LLC | $11.9M | 31,998 | 0.12% | 27q | -10.8%-$1.4M |
| DEUTSCHE BANK AG\ | $11.8M | 31,836 | 0.00% | 30q | +28.2%+$2.6M |
| JANE STREET GROUP, LLC | $10.6M | 956 | 0.00% | 14q | HELD |
| Fisher Asset Management, LLC | $10.3M | 27,676 | 0.00% | 3q | HELD |
| D. E. Shaw & Co., Inc. | $10.2M | options only | 0.00% | 18q | OPTIONS |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | $9.6M | 25,867 | 0.01% | 29q | -28.3%-$3.8M |
| Aberdeen Group plc | $9.3M | 25,141 | 0.01% | 10q | -16.6%-$1.9M |
| Atle Fund Management AB | $8.9M | 24,019 | 2.40% | 12q | -36.1%-$5.0M |
| ALLIANCEBERNSTEIN L.P. | $8.8M | 34,039 | 0.00% | 29q | +6.6%+$545.1K |
| TD Asset Management Inc | $8.4M | 22,712 | 0.01% | 13q | -47.6%-$7.7M |
| Elmind Capital, LP | $8.2M | 22,000 | 2.05% | 3q | HELD |
| VANGUARD ASSET MANAGEMENT, Ltd | $8.0M | 21,390 | 0.01% | 2q | +3.8%+$291.4K |
| Creative Planning | $7.6M | 20,318 | 0.00% | 10q | +27.5%+$1.6M |
| Pinnacle Financial Partners, Inc. | $7.5M | 20,243 | 0.05% | 3q | HELD |
| Tetragon Partners GP Ltd | $7.3M | 19,668 | 1.15% | 4q | HELD |
| Louisiana State Employees Retirement System | $7.2M | 22,900 | 0.06% | 9q | +100.9%+$3.6M |
| Lisanti Capital Growth, LLC | $7.1M | 19,050 | 1.56% | 2q | +2.9%+$198.8K |
| VAN ECK ASSOCIATES CORP | $6.3M | 17,071 | 0.00% | new | NEW |
| ADAR1 Capital Management, LLC | $6.1M | 16,420 | 0.28% | 4q | -18.0%-$1.3M |
| Cinctive Capital Management LP | $6.1M | 16,367 | 0.22% | 2q | +469.5%+$5.0M |
| Rhenman & Partners Asset Management AB | $6.1M | 16,325 | 0.57% | 10q | -2.1%-$130.1K |
| Informed Momentum Co LLC | $6.0M | 16,227 | 0.54% | 3q | -1.6%-$95.1K |
| Mediolanum International Funds Ltd | $6.0M | 15,940 | 0.05% | new | NEW |
| CASTLEARK MANAGEMENT LLC | $6.0M | 16,150 | 0.16% | 3q | -48.9%-$5.8M |
Showing the largest 100 of 430 reported holders.
Quarter by quarter
Coverage begins with the quarter ending 2018-12-31. Earlier filings exist only as occasional late amendments, too sparse to describe a market, so they are not shown.
| Quarter | Holders | Value | Shares | New | Added | Trimmed | Options |
|---|---|---|---|---|---|---|---|
| Q2 2026 | 400 | $11.0B | 28,943,716 | 88 | 162 | 100 | 1.9% |
| Q1 2026 | 344 | $7.2B | 27,632,299 | 67 | 127 | 84 | 1.6% |
| Q4 2025 | 311 | $6.9B | 27,540,330 | 59 | 94 | 93 | 1.1% |
| Q3 2025 | 263 | $5.0B | 27,393,556 | 44 | 93 | 72 | 3.2% |
| Q2 2025 | 254 | $3.8B | 27,061,572 | 41 | 86 | 85 | 3.3% |
| Q1 2025 | 274 | $4.9B | 26,534,029 | 59 | 79 | 95 | 1.5% |
| Q4 2024 | 242 | $4.3B | 26,586,737 | 23 | 82 | 82 | 2.3% |
| Q3 2024 | 259 | $5.1B | 27,222,132 | 49 | 90 | 78 | 3.0% |
| Q2 2024 | 224 | $5.1B | 27,233,844 | 44 | 89 | 61 | 1.9% |
| Q1 2024 | 218 | $4.5B | 24,172,879 | 65 | 57 | 67 | 5.3% |
| Q4 2023 | 178 | $3.0B | 23,191,153 | 20 | 62 | 51 | 5.0% |
| Q3 2023 | 168 | $2.6B | 22,072,846 | 15 | 73 | 41 | 2.3% |
| Q2 2023 | 166 | $2.5B | 20,781,788 | 39 | 51 | 52 | 1.8% |
| Q1 2023 | 138 | $1.7B | 20,803,167 | 21 | 45 | 41 | 1.2% |
| Q4 2022 | 126 | $1.3B | 16,538,658 | 18 | 48 | 33 | 1.9% |
| Q3 2022 | 151 | $1.5B | 20,883,747 | 22 | 54 | 40 | 1.1% |
| Q2 2022 | 136 | $1.4B | 20,785,500 | 19 | 42 | 49 | 0.9% |
| Q1 2022 | 134 | $1.4B | 20,596,194 | 21 | 49 | 46 | 0.6% |
| Q4 2021 | 140 | $1.4B | 19,348,973 | 34 | 55 | 21 | 3.6% |
| Q3 2021 | 123 | $908.8M | 16,292,481 | 15 | 45 | 35 | 6.4% |
| Q2 2021 | 119 | $1.1B | 16,402,641 | 17 | 51 | 30 | 1.2% |
| Q1 2021 | 116 | $1.3B | 16,476,350 | 15 | 49 | 28 | 0.5% |
| Q4 2020 | 109 | $841.4M | 13,937,271 | 19 | 34 | 31 | 0.4% |
| Q3 2020 | 99 | $624.9M | 14,446,600 | 4 | 44 | 32 | 0.2% |
| Q2 2020 | 111 | $595.2M | 14,278,543 | 32 | 47 | 22 | 0.4% |
| Q1 2020 | 90 | $501.9M | 11,571,591 | 14 | 34 | 28 | 0.0% |
| Q4 2019 | 90 | $643.2M | 11,600,820 | 12 | 30 | 31 | 0.0% |
| Q3 2019 | 85 | $400.4M | 11,469,827 | 14 | 35 | 19 | 0.0% |
| Q2 2019 | 76 | $397.7M | 9,833,504 | 30 | 26 | 14 | 0.0% |
| Q1 2019 | 57 | $223.1M | 6,714,667 | 17 | 17 | 16 | 0.0% |
| Q4 2018 | 45 | $130.3M | 6,269,192 | 2 | 1 | 1 | 0.0% |