HolderBook

FULCRUM THERAPEUTICS INC (FULC)

Institutional ownership reported to the SEC as of Q2 2026, across 28 quarters.

151
Reporting holders
$315.6M
Reported value
110.9%
Of shares outstanding
1.7%
Held as options
-12
Holder change

Institutions report 84,636,106 shares against 76,297,257 outstanding. Shares only - option lines are excluded, which is why this can be compared with the company at all. The count comes from the cover page of the company's own most recent report, so it is dated when that was filed rather than at quarter end. Over 100% because an adviser and a sub-adviser can both report the same shares, and both are counted.

Options share is the part of reported value carried in derivative lines rather than shares. A high figure means institutions are expressing a view on this security without owning much of it.

Holders

FilerValueShares Their book Held Change
Nantahala Capital Management, LLC$40.1M10,950,0800.67%8q+259.0%+$28.9M
BlackRock, Inc.$32.3M8,824,2590.00%8q+63.7%+$12.6M
EcoR1 Capital, LLC$24.0M6,549,8661.17%newNEW
TANG CAPITAL MANAGEMENT LLC$23.9M6,521,4121.08%newNEW
MONTANOVA CAPITAL, LLC$13.5M3,680,9210.25%22q-43.9%-$10.5M
D. E. Shaw & Co., Inc.$11.1M3,044,3850.01%20q+87.5%+$5.2M
CITADEL ADVISORS LLC$10.8M2,704,5050.00%21q+109.2%+$5.6M
VANGUARD CAPITAL MANAGEMENT LLC$9.9M2,697,2160.00%2qHELD
JANE STREET GROUP, LLC$8.4M2,217,4980.00%15q+614.4%+$7.2M
STATE STREET CORP$7.5M2,037,0250.00%27q+31.4%+$1.8M
ADAGE CAPITAL PARTNERS GP, L.L.C.$7.3M2,000,0000.01%20q+400.0%+$5.9M
GSK plc$6.5M1,785,7141.09%3qHELD
Qube Research & Technologies Ltd$6.4M1,748,4670.01%3q+79.4%+$2.8M
Assenagon Asset Management S.A.$6.1M1,670,4080.00%2q+39.9%+$1.7M
RENAISSANCE TECHNOLOGIES LLC$6.0M1,647,8000.01%6q+12016.2%+$6.0M
ADAR1 Capital Management, LLC$5.7M1,565,0290.26%11q+1098.7%+$5.3M
MILLENNIUM MANAGEMENT LLC$5.4M1,485,8030.00%14q+316.8%+$4.1M
GEODE CAPITAL MANAGEMENT, LLC$5.2M1,432,1330.00%28q-3.7%-$199.2K
SUSQUEHANNA INTERNATIONAL GROUP, LLP$5.2M1,180,9460.00%20q+1065.4%+$4.8M
MARSHALL WACE, LLP$5.0M1,358,4230.00%newNEW
UBS Group AG$4.6M1,253,9090.00%15q+297.8%+$3.4M
AQR CAPITAL MANAGEMENT LLC$4.0M1,103,2610.00%3q+103.1%+$2.0M
GOLDMAN SACHS GROUP INC$4.0M1,094,4250.00%23q+91.4%+$1.9M
Ikarian Capital, LLC$3.8M1,049,1610.41%8qHELD
BANK OF AMERICA CORP /DE/$3.8M1,043,0290.00%28q+724.1%+$3.4M
Jump Financial, LLC$3.7M1,005,0000.03%3q+171.8%+$2.3M
DIMENSIONAL FUND ADVISORS LP$3.5M960,5470.00%22q-15.0%-$621.3K
TWO SIGMA INVESTMENTS, LP$3.0M812,7660.00%2q+484.7%+$2.5M
VANGUARD PORTFOLIO MANAGEMENT LLC$2.9M782,1440.00%2q+30.5%+$668.9K
Connor, Clark & Lunn Investment Management Ltd.$2.7M745,3170.01%8q+1.2%+$31.6K
Balyasny Asset Management L.P.$2.5M692,3720.00%5q-61.1%-$4.0M
Y-Intercept (Hong Kong) Ltd$2.5M681,8320.05%4q+344.6%+$1.9M
Point72 Asset Management, L.P.$2.4M651,4270.00%3q-68.6%-$5.2M
NORTHERN TRUST CORP$1.8M487,8690.00%28q+3.1%+$54.5K
CHARLES SCHWAB INVESTMENT MANAGEMENT INC$1.6M433,2200.00%26q+1.5%+$23.2K
Sixth Street Partners Management Company, L.P.$1.6M433,2200.00%newNEW
SILVERARC CAPITAL MANAGEMENT, LLC$1.4Moptions only0.15%3qOPTIONS
VANGUARD FIDUCIARY TRUST CO$1.3M345,6480.00%2q+4.8%+$57.7K
SIMPLEX TRADING, LLC$1.2Moptions only0.00%newOPTIONS
BOOTHBAY FUND MANAGEMENT, LLC$1.1M303,9880.01%8qHELD
Peapod Lane Capital LLC$1.0M285,7980.71%newNEW
WELLINGTON MANAGEMENT GROUP LLP$1.0M285,0840.00%5q+140.4%+$609.3K
Engineers Gate Manager LP$885.7K242,0000.01%2q+91.9%+$424.2K
Hennion & Walsh Asset Management, Inc.$855.9K233,8510.02%newNEW
EntryPoint Capital, LLC$794.9K217,1990.19%3q+380.0%+$629.3K
XTX Topco Ltd$765.8K209,2470.01%3q+192.2%+$503.8K
Quadrature Capital Ltd$692.2K189,1190.01%newNEW
MORGAN STANLEY$674.1K184,1920.00%28q+6.3%+$39.7K
ALLIANCEBERNSTEIN L.P.$639.4K83,3700.00%12q+141.2%+$374.3K
GROUP ONE TRADING LLC$610.7K3,5560.00%20q-93.4%-$8.6M
AMERICAN CENTURY COMPANIES INC$570.5K155,8680.00%14qHELD
Nuveen, LLC$566.8K154,8710.00%6q+19.5%+$92.4K
Bank of New York Mellon Corp$565.5K154,5130.00%9q+3.0%+$16.7K
Simplify Asset Management Inc.$562.9K153,7940.01%14q+32.6%+$138.3K
Fiduciary Trust Co$499.8K136,5550.01%28qHELD
Squarepoint Ops LLC$463.2K126,5580.00%5q-28.1%-$180.8K
Verdad Advisers, LP$458.3K125,2240.44%newNEW
BNP PARIBAS FINANCIAL MARKETS$435.7K119,0380.00%7q+741.4%+$383.9K
HSBC HOLDINGS PLC$426.5K109,3530.00%8q+86.5%+$197.8K
Rangeley Capital, LLC$420.5K114,8900.38%newNEW
Invesco Ltd.$414.7K113,3190.00%11q+2.0%+$8.0K
Russell Investments Group, Ltd.$381.4K104,1990.00%8q+31.6%+$91.7K
CANADA PENSION PLAN INVESTMENT BOARD$374.8K102,4000.00%2q+456.5%+$307.4K
ALGERT GLOBAL LLC$371.0K101,3600.00%2q+53.3%+$129.1K
PANAGORA ASSET MANAGEMENT INC$349.6K95,5210.00%2q-60.8%-$541.8K
FMR LLC$337.9K92,3270.00%28q+51.3%+$114.5K
Headlands Technologies LLC$328.4K89,7230.03%newNEW
Susquehanna Portfolio Strategies, LLC$313.2K85,5800.00%2q+342.9%+$242.5K
BARCLAYS PLC$305.1K83,3730.00%11q-5.7%-$18.6K
AXQ CAPITAL, LP$298.2K81,4830.03%3q+269.7%+$217.6K
RHUMBLINE ADVISERS$268.8K73,4430.00%25q+11.0%+$26.6K
RBF Capital, LLC$256.2K70,0000.01%13qHELD
PRELUDE CAPITAL MANAGEMENT, LLC$248.4K67,8570.02%newNEW
ALPS ADVISORS INC$247.5K67,6320.00%newNEW
CITIGROUP INC$229.8K62,7740.00%28q+167.9%+$144.0K
FOX RUN MANAGEMENT, L.L.C.$206.6K56,4460.03%newNEW
DEUTSCHE BANK AG\$191.7K52,3810.00%11q+7.3%+$13.0K
WELLS FARGO & COMPANY/MN$181.9K49,6960.00%28q+10.2%+$16.8K
STRS OHIO$169.1K46,2000.00%8q-6.3%-$11.3K
IMC-Chicago, LLC$166.9Koptions only0.00%newOPTIONS
MERCER GLOBAL ADVISORS INC /ADV$156.4K42,7400.00%2q+293.3%+$116.7K
JPMORGAN CHASE & CO$154.3K41,3710.00%28q+38.9%+$43.2K
COMMONWEALTH EQUITY SERVICES, LLC$146.4K40,0000.00%11q-0.7%-$1.1K
Marquette Asset Management, LLC$141.1K38,5520.02%newNEW
LMR Partners LLP$128.1K30,0000.00%5qHELD
MetLife Investment Management, LLC$124.7K34,0790.00%9q+2.8%+$3.3K
FRANKLIN RESOURCES INC$124.7K34,0630.00%13q-37.7%-$75.4K
PROFUND ADVISORS LLC$119.0K32,5140.00%2q+109.8%+$62.3K
SEI INVESTMENTS CO$112.3K30,6810.00%newNEW
COUNTRY TRUST BANK$110.0K30,0410.00%26qHELD
Aigen Investment Management, LP$108.0K29,5120.03%newNEW
Scientech Research LLC$104.6K28,5840.08%newNEW
Mariner, LLC$102.9K28,1040.00%2q+20.8%+$17.7K
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd.$100.0K27,3250.00%8q-2.7%-$2.8K
Graham Capital Management, L.P.$91.7K25,0670.00%8q-41.4%-$64.7K
STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM$91.7K25,0520.00%newNEW
Rafferty Asset Management, LLC$89.8K24,5380.00%newNEW
Creative Planning$78.2K21,3730.00%5q-66.7%-$156.3K
Castleview Partners, LLC$69.9K19,1000.03%newNEW
Vanguard Global Advisers, LLC$69.0K18,8580.00%2q-51.0%-$72.0K

Five percent filings

Anyone crossing 5% of a company must say so within days - far sooner than the next quarterly holdings report. A 13D declares an intent to influence the company; a 13G is the passive version. See all activist filings →

FiledFormFiler % of class
2026-08-1413G/AMontanova Capital, LLCwith 2 co-filers5.5%
2026-08-1413GNantahala Capital Management, LLCwith 2 co-filers8.2%
2026-08-1413G/ATCG Crossover GP II, LLCwith 2 co-filers0.0%
2026-08-1413G/ARA Capital Management, L.P.with 3 co-filers0.0%
2026-08-0313GBANK OF AMERICA CORP /DE/6.7%
2026-07-2813G/ABlackRock, Inc.7.2%
2026-07-1713GBlackRock Portfolio Management LLC6.0%
2026-07-1513G/ATANG CAPITAL MANAGEMENT, LLCwith 5 co-filers10.4%

Quarter by quarter

Coverage begins with the quarter ending 2018-12-31. Earlier filings exist only as occasional late amendments, too sparse to describe a market, so they are not shown.

QuarterHoldersValue SharesNewAdded TrimmedOptions
Q2 2026151$315.6M84,636,1063170291.7%
Q1 2026163$549.6M70,532,8083170381.6%
Q4 2025163$761.5M66,307,2835641451.5%
Q3 2025119$484.9M52,532,0722438380.4%
Q2 2025114$372.9M53,192,7722530441.8%
Q1 2025106$145.5M50,487,6821627380.1%
Q4 2024113$246.4M51,361,9451630362.1%
Q3 2024125$225.1M54,381,24944303413.8%
Q2 2024116$434.7M64,043,3913238268.7%
Q1 2024116$617.5M62,206,6873234275.0%
Q4 202393$422.4M61,819,7342123201.3%
Q3 202374$252.7M56,071,5061316221.5%
Q2 202382$182.2M54,507,1681525261.3%
Q1 2023102$183.6M63,713,5212248191.1%
Q4 202297$356.7M48,403,4372135231.2%
Q3 2022105$427.6M52,182,8702536231.3%
Q2 2022102$201.5M40,132,2181940202.4%
Q1 2022110$937.4M39,474,7112126390.8%
Q4 2021112$667.0M37,494,0253137200.7%
Q3 2021102$1.0B36,552,2864534170.6%
Q2 202167$283.9M27,092,7491030160.0%
Q1 202168$317.0M26,913,1101024160.0%
Q4 202066$259.6M22,170,8771324120.0%
Q3 202053$163.3M20,593,815817120.0%
Q2 202060$373.6M20,456,011182290.0%
Q1 202047$201.2M16,847,956122450.0%
Q4 201938$263.0M15,843,636215110.0%
Q3 201939$105.1M15,906,36339000.0%