C4 THERAPEUTICS INC (CCCC)
Institutional ownership reported to the SEC as of Q2 2026, across 23 quarters.
147
Reporting holders
$581.5M
Reported value
100.7%
Of shares outstanding
0.9%
Held as options
+25
Holder change
Institutions report 123,854,397 shares against 123,025,136 outstanding. Shares only - option lines are excluded, which is why this can be compared with the company at all. The count comes from the cover page of the company's own most recent report, so it is dated when that was filed rather than at quarter end. Over 100% because an adviser and a sub-adviser can both report the same shares, and both are counted.
Options share is the part of reported value carried in derivative lines rather than shares. A high figure means institutions are expressing a view on this security without owning much of it.
Holders
| Filer | Value | Shares | Their book | Held | Change |
|---|---|---|---|---|---|
| Lynx1 Capital Management LP | $68.4M | 14,653,382 | 4.98% | 12q | +109.4%+$35.7M |
| MORGAN STANLEY | $41.4M | 8,867,338 | 0.00% | 23q | -2.3%-$957.6K |
| RA CAPITAL MANAGEMENT, L.P. | $37.4M | 8,000,000 | 0.32% | 3q | HELD |
| BlackRock, Inc. | $36.9M | 7,896,718 | 0.00% | 8q | +285.5%+$27.3M |
| Squadron Capital Management LLC | $35.5M | 7,200,000 | 11.01% | 2q | +220.0%+$24.4M |
| Bain Capital Life Sciences Investors, LLC | $33.5M | 7,171,910 | 1.99% | 23q | HELD |
| JPMORGAN CHASE & CO | $20.7M | 4,747,424 | 0.00% | 23q | +47.3%+$6.6M |
| VANGUARD CAPITAL MANAGEMENT LLC | $20.6M | 4,417,731 | 0.00% | 2q | +14.4%+$2.6M |
| CITADEL ADVISORS LLC | $20.0M | 4,187,580 | 0.00% | 4q | +66.8%+$8.0M |
| GOLDMAN SACHS GROUP INC | $16.5M | 3,530,991 | 0.00% | 21q | +47.9%+$5.3M |
| WASATCH ADVISORS LP | $16.5M | 3,522,644 | 0.11% | 22q | +18.9%+$2.6M |
| TWO SIGMA INVESTMENTS, LP | $16.2M | 3,469,707 | 0.01% | 10q | +14.3%+$2.0M |
| Soleus Capital Management, L.P. | $15.8M | 3,377,981 | 0.54% | 23q | -11.2%-$2.0M |
| SILVERARC CAPITAL MANAGEMENT, LLC | $14.2M | 3,032,060 | 1.47% | 4q | +58.6%+$5.2M |
| BANK OF AMERICA CORP /DE/ | $12.4M | 2,656,359 | 0.00% | 23q | +12.6%+$1.4M |
| GEODE CAPITAL MANAGEMENT, LLC | $11.8M | 2,522,163 | 0.00% | 23q | +165.2%+$7.3M |
| Ikarian Capital, LLC | $11.4M | 2,433,000 | 1.22% | new | NEW |
| STATE STREET CORP | $9.9M | 2,115,621 | 0.00% | 23q | +452.4%+$8.1M |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $9.5M | 1,732,210 | 0.00% | 22q | +34.6%+$2.4M |
| Candriam S.C.A. | $8.4M | 1,796,937 | 0.04% | new | NEW |
| D. E. Shaw & Co., Inc. | $8.1M | 1,740,989 | 0.00% | 17q | +64.2%+$3.2M |
| Patient Square Capital LP | $7.5M | 1,608,815 | 1.16% | new | NEW |
| HighVista Strategies LLC | $6.3M | 1,348,136 | 1.44% | new | NEW |
| RENAISSANCE TECHNOLOGIES LLC | $5.6M | 1,189,828 | 0.01% | 6q | -51.7%-$5.9M |
| DIMENSIONAL FUND ADVISORS LP | $5.5M | 1,188,507 | 0.00% | 16q | +168.6%+$3.5M |
| NORTHERN TRUST CORP | $5.4M | 1,160,547 | 0.00% | 23q | +512.5%+$4.5M |
| CONGRESS ASSET MANAGEMENT CO | $4.7M | 1,003,437 | 0.03% | 2q | +20.8%+$807.0K |
| FMR LLC | $4.2M | 894,054 | 0.00% | 23q | +228.3%+$2.9M |
| UBS Group AG | $3.9M | 828,970 | 0.00% | 23q | +284.0%+$2.9M |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $3.6M | 781,060 | 0.00% | 23q | +72.7%+$1.5M |
| Sixth Street Partners Management Company, L.P. | $3.6M | 781,060 | 0.00% | new | NEW |
| BOOTHBAY FUND MANAGEMENT, LLC | $3.4M | 736,331 | 0.05% | new | NEW |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $3.2M | 680,094 | 0.00% | new | NEW |
| VANGUARD FIDUCIARY TRUST CO | $2.8M | 609,146 | 0.00% | 2q | +25.8%+$583.8K |
| ExodusPoint Capital Management, LP | $2.7M | 580,195 | 0.02% | 3q | +1121.3%+$2.5M |
| Velan Capital Investment Management LP | $2.7M | 570,000 | 1.62% | new | NEW |
| STEMPOINT CAPITAL LP | $2.4M | 523,648 | 0.42% | 2q | -42.2%-$1.8M |
| Rockefeller Capital Management L.P. | $2.3M | 495,817 | 0.00% | new | NEW |
| Nuveen, LLC | $2.3M | 484,010 | 0.00% | new | NEW |
| WELLS FARGO & COMPANY/MN | $2.1M | 452,701 | 0.00% | 14q | -73.9%-$6.0M |
| Man Group plc | $1.9M | 408,648 | 0.00% | 6q | +59.3%+$710.7K |
| PLATINUM INVESTMENT MANAGEMENT LTD | $1.8M | 384,766 | 0.44% | 2q | HELD |
| Seven Fleet Capital Management LP | $1.8M | 381,169 | 0.29% | 2q | +567.8%+$1.5M |
| Qube Research & Technologies Ltd | $1.7M | 370,554 | 0.00% | 4q | -50.7%-$1.8M |
| Atom Investors LP | $1.7M | 364,351 | 0.15% | 3q | +167.8%+$1.1M |
| JANE STREET GROUP, LLC | $1.6M | 302,750 | 0.00% | 11q | -75.7%-$5.1M |
| Susquehanna Portfolio Strategies, LLC | $1.6M | 335,079 | 0.02% | 5q | +28.7%+$349.3K |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | $1.5M | 325,000 | 0.00% | new | NEW |
| Connor, Clark & Lunn Investment Management Ltd. | $1.4M | 300,734 | 0.00% | 3q | +8.5%+$110.0K |
| ADAR1 Capital Management, LLC | $1.4M | 291,957 | 0.06% | 2q | +579.0%+$1.2M |
| Invesco Ltd. | $1.4M | 290,226 | 0.00% | 23q | +18.7%+$213.5K |
| PANAGORA ASSET MANAGEMENT INC | $1.2M | 264,947 | 0.00% | 2q | +205.4%+$832.1K |
| LPL Financial LLC | $1.2M | 253,165 | 0.00% | 9q | +2.6%+$29.7K |
| Bank of New York Mellon Corp | $1.2M | 249,517 | 0.00% | new | NEW |
| WELLINGTON MANAGEMENT GROUP LLP | $1.1M | 227,768 | 0.00% | new | NEW |
| MARSHALL WACE, LLP | $1.1M | 227,003 | 0.00% | 4q | +46.0%+$333.9K |
| MILLENNIUM MANAGEMENT LLC | $1.0M | 215,386 | 0.00% | 14q | -84.5%-$5.5M |
| Caption Management, LLC | $989.1K | 35,000 | 0.00% | new | NEW |
| Verition Fund Management LLC | $887.3K | 190,000 | 0.00% | new | NEW |
| Jump Financial, LLC | $853.2K | 182,700 | 0.01% | new | NEW |
| Point72 Asset Management, L.P. | $812.4K | 173,965 | 0.00% | 3q | +2.9%+$22.7K |
| Squarepoint Ops LLC | $797.8K | 170,834 | 0.00% | 5q | +320.1%+$607.9K |
| Headlands Technologies LLC | $719.0K | 153,972 | 0.08% | new | NEW |
| AMERICAN CENTURY COMPANIES INC | $703.7K | 150,681 | 0.00% | 4q | +76.4%+$304.7K |
| XTX Topco Ltd | $632.5K | 135,438 | 0.01% | 6q | +187.2%+$412.3K |
| Palumbo Wealth Management LLC | $618.4K | 132,417 | 0.13% | new | NEW |
| RHUMBLINE ADVISERS | $615.9K | 131,877 | 0.00% | 23q | +4755.6%+$603.2K |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | $612.2K | 131,100 | 0.01% | 6q | HELD |
| Walleye Capital LLC | $539.0K | 115,125 | 0.00% | 4q | -51.9%-$580.6K |
| ALPS ADVISORS INC | $524.0K | 112,214 | 0.00% | new | NEW |
| CANADA PENSION PLAN INVESTMENT BOARD | $474.0K | 101,500 | 0.00% | 3q | -25.1%-$159.2K |
| DEUTSCHE BANK AG\ | $461.7K | 98,873 | 0.00% | new | NEW |
| Vienna Powszechne Towarzystwo Emerytalne S.A. Vienna Insurance Group | $396.9K | 85,000 | 0.10% | 19q | HELD |
| BARCLAYS PLC | $348.0K | 74,516 | 0.00% | 18q | -76.6%-$1.1M |
| BNP PARIBAS FINANCIAL MARKETS | $347.3K | 74,373 | 0.00% | 7q | -60.9%-$541.6K |
| Crestwood Advisors Group, LLC | $310.7K | 66,536 | 0.00% | 5q | HELD |
| INTREPID FAMILY OFFICE LLC | $303.6K | 65,000 | 0.22% | 7q | +8.3%+$23.4K |
| CV Advisors LLC | $303.6K | 65,000 | 0.06% | new | NEW |
| MetLife Investment Management, LLC | $286.7K | 61,393 | 0.00% | new | NEW |
| Jain Global LLC | $268.8K | 57,562 | 0.00% | 3q | -7.7%-$22.5K |
| CITIGROUP INC | $230.6K | 49,389 | 0.00% | 23q | +16.4%+$32.5K |
| GROUP ONE TRADING LLC | $224.0K | 21,773 | 0.00% | new | NEW |
| SIMPLEX TRADING, LLC | $221.4K | options only | 0.00% | 19q | OPTIONS |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | $217.0K | 46,474 | 0.00% | new | NEW |
| Corient Private Wealth LP | $199.8K | 42,774 | 0.00% | 12q | +100.0%+$99.9K |
| SEI INVESTMENTS CO | $197.9K | 42,376 | 0.00% | 2q | +68.6%+$80.5K |
| Quadrature Capital Ltd | $171.5K | 36,726 | 0.00% | 3q | -41.5%-$121.6K |
| ALLIANCEBERNSTEIN L.P. | $170.4K | 64,780 | 0.00% | new | NEW |
| Vanguard Global Advisers, LLC | $158.0K | 33,832 | 0.00% | 2q | HELD |
| Dynamic Technology Lab Private Ltd | $153.0K | 32,828 | 0.03% | new | NEW |
| PRUDENTIAL FINANCIAL INC | $145.9K | 31,235 | 0.00% | 4q | +95.8%+$71.4K |
| Police & Firemen's Retirement System of New Jersey | $139.6K | 29,893 | 0.00% | new | NEW |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | $128.5K | 27,513 | 0.00% | new | NEW |
| JACOBS LEVY EQUITY MANAGEMENT, INC | $117.3K | 25,111 | 0.00% | 2q | -90.5%-$1.1M |
| Cresset Asset Management, LLC | $116.8K | 25,000 | 0.00% | 9q | HELD |
| NEW YORK STATE COMMON RETIREMENT FUND | $112.5K | 24,100 | 0.00% | new | NEW |
| Aster Capital Management (DIFC) Ltd | $111.2K | 77,734 | 0.01% | new | NEW |
| StoneX Group Inc. | $102.3K | 22,420 | 0.00% | new | NEW |
| Scientech Research LLC | $99.3K | 21,260 | 0.08% | new | NEW |
| Quantbot Technologies LP | $97.3K | 20,827 | 0.00% | new | NEW |
Five percent filings
Anyone crossing 5% of a company must say so within days - far sooner than the next quarterly holdings report. A 13D declares an intent to influence the company; a 13G is the passive version. See all activist filings →
| Filed | Form | Filer | % of class |
|---|---|---|---|
| 2026-08-14 | 13G/A | Lynx1 Capital Management LPwith 1 co-filers | 10.0% |
| 2026-08-14 | 13G/A | RA Capital Management, L.P.with 3 co-filers | 9.9% |
| 2026-08-14 | 13G/A | Squadron Master Fund LPwith 3 co-filers | 6.9% |
| 2026-08-12 | 13G/A | Morgan Stanleywith 2 co-filers | 8.0% |
| 2026-07-27 | 13G | BlackRock, Inc. | 6.9% |
Quarter by quarter
Coverage begins with the quarter ending 2018-12-31. Earlier filings exist only as occasional late amendments, too sparse to describe a market, so they are not shown.
| Quarter | Holders | Value | Shares | New | Added | Trimmed | Options |
|---|---|---|---|---|---|---|---|
| Q2 2026 | 147 | $581.5M | 123,854,397 | 52 | 53 | 28 | 0.9% |
| Q1 2026 | 122 | $220.3M | 83,803,044 | 30 | 37 | 30 | 0.5% |
| Q4 2025 | 98 | $152.1M | 79,173,101 | 21 | 42 | 18 | 0.6% |
| Q3 2025 | 96 | $117.6M | 52,480,870 | 24 | 26 | 34 | 1.1% |
| Q2 2025 | 96 | $78.2M | 54,638,707 | 24 | 29 | 27 | 0.1% |
| Q1 2025 | 107 | $101.7M | 63,527,615 | 21 | 36 | 26 | 0.1% |
| Q4 2024 | 110 | $234.0M | 64,241,814 | 17 | 37 | 29 | 1.2% |
| Q3 2024 | 112 | $367.4M | 63,552,072 | 29 | 35 | 27 | 1.4% |
| Q2 2024 | 108 | $283.5M | 60,520,383 | 32 | 28 | 30 | 1.4% |
| Q1 2024 | 96 | $471.7M | 56,445,361 | 37 | 25 | 22 | 2.2% |
| Q4 2023 | 85 | $261.0M | 43,955,780 | 26 | 25 | 22 | 4.9% |
| Q3 2023 | 79 | $59.7M | 32,123,158 | 7 | 29 | 24 | 0.1% |
| Q2 2023 | 91 | $83.6M | 30,432,291 | 14 | 33 | 33 | 0.1% |
| Q1 2023 | 101 | $99.1M | 31,513,761 | 16 | 37 | 29 | 0.1% |
| Q4 2022 | 94 | $192.7M | 32,619,488 | 12 | 31 | 23 | 0.1% |
| Q3 2022 | 115 | $353.3M | 40,259,262 | 16 | 44 | 30 | 0.1% |
| Q2 2022 | 116 | $300.2M | 39,435,871 | 28 | 34 | 34 | 0.8% |
| Q1 2022 | 123 | $923.2M | 37,323,144 | 27 | 44 | 31 | 2.0% |
| Q4 2021 | 120 | $1.2B | 38,139,891 | 19 | 42 | 30 | 0.2% |
| Q3 2021 | 112 | $1.5B | 34,492,145 | 18 | 51 | 21 | 0.3% |
| Q2 2021 | 107 | $1.3B | 34,204,438 | 37 | 44 | 12 | 0.3% |
| Q1 2021 | 83 | $926.8M | 25,097,449 | 17 | 27 | 20 | 0.0% |
| Q4 2020 | 75 | $743.5M | 22,706,751 | 70 | 0 | 0 | 0.0% |