ARROWHEAD PHARMACEUTICALS IN (ARWR)
Institutional ownership reported to the SEC as of Q2 2026, across 31 quarters.
477
Reporting holders
$9.8B
Reported value
83.4%
Of shares outstanding
2.3%
Held as options
+66
Holder change
Institutions report 117,766,457 shares against 141,254,467 outstanding. Shares only - option lines are excluded, which is why this can be compared with the company at all. The count comes from the cover page of the company's own most recent report, so it is dated when that was filed rather than at quarter end.
Options share is the part of reported value carried in derivative lines rather than shares. A high figure means institutions are expressing a view on this security without owning much of it.
Holders
| Filer | Value | Shares | Their book | Held | Change |
|---|---|---|---|---|---|
| BlackRock, Inc. | $1.2B | 14,830,553 | 0.02% | 8q | -18.3%-$271.5M |
| Avoro Capital Advisors LLC | $925.6M | 11,355,555 | 8.31% | 13q | +6.1%+$53.4M |
| FMR LLC | $655.3M | 8,039,804 | 0.03% | 31q | +10.6%+$63.0M |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $517.7M | 6,351,355 | 0.02% | 2q | -11.1%-$64.8M |
| VANGUARD CAPITAL MANAGEMENT LLC | $498.1M | 6,110,953 | 0.01% | 2q | +1.3%+$6.4M |
| STATE STREET CORP | $464.2M | 5,694,640 | 0.01% | 31q | -12.3%-$65.3M |
| NORGES BANK | $317.6M | 3,896,536 | 0.03% | 26q | +128.6%+$178.7M |
| Invesco Ltd. | $316.6M | 3,883,976 | 0.03% | 31q | +18.4%+$49.2M |
| GEODE CAPITAL MANAGEMENT, LLC | $298.8M | 3,530,612 | 0.02% | 31q | -17.5%-$63.3M |
| FRED ALGER MANAGEMENT, LLC | $269.1M | 3,301,919 | 0.90% | 4q | -1.2%-$3.3M |
| BAKER BROS. ADVISORS LP | $162.4M | 1,992,783 | 0.81% | 5q | HELD |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $153.9M | 596,573 | 0.01% | 31q | +57.5%+$56.2M |
| Siren, L.L.C. | $139.8M | 1,715,476 | 2.83% | 8q | +6.2%+$8.2M |
| Vestal Point Capital, LP | $128.4M | 1,575,000 | 3.00% | 3q | -30.8%-$57.1M |
| DEERFIELD MANAGEMENT COMPANY, L.P. | $113.2M | 1,389,055 | 1.18% | 4q | -11.7%-$15.0M |
| FIRST TRUST ADVISORS LP | $110.3M | 1,352,918 | 0.06% | 4q | +807.1%+$98.1M |
| Driehaus Capital Management LLC | $110.1M | 1,350,556 | 0.64% | 4q | +13.5%+$13.1M |
| Jupiter Topco LLC | $99.6M | 1,221,596 | 0.04% | new | FIRST |
| NORTHERN TRUST CORP | $97.2M | 1,192,868 | 0.01% | 31q | -28.0%-$37.7M |
| DIMENSIONAL FUND ADVISORS LP | $96.3M | 1,181,608 | 0.02% | 5q | +94.2%+$46.7M |
| GOLDMAN SACHS GROUP INC | $93.7M | 1,150,007 | 0.01% | 31q | -33.9%-$48.1M |
| BANK OF AMERICA CORP /DE/ | $92.9M | 1,139,810 | 0.01% | 31q | +7.1%+$6.1M |
| Hood River Capital Management LLC | $91.4M | 1,120,747 | 0.66% | 2q | +6.1%+$5.2M |
| Holocene Advisors, LP | $90.2M | 1,106,177 | 0.20% | new | NEW |
| MORGAN STANLEY | $88.4M | 1,084,835 | 0.00% | 35q | +12.9%+$10.1M |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | $78.6M | 964,479 | 0.01% | 31q | -27.5%-$29.9M |
| Fisher Asset Management, LLC | $78.1M | 957,691 | 0.02% | 9q | -14.0%-$12.7M |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $75.3M | 923,927 | 0.01% | 31q | -22.5%-$21.9M |
| Sixth Street Partners Management Company, L.P. | $75.3M | 923,927 | 0.01% | new | NEW |
| VANGUARD FIDUCIARY TRUST CO | $73.1M | 896,738 | 0.02% | 2q | -7.1%-$5.6M |
| UBS Group AG | $70.2M | 861,520 | 0.01% | 31q | -35.5%-$38.7M |
| Bank of New York Mellon Corp | $70.1M | 859,538 | 0.01% | 31q | -10.5%-$8.2M |
| SUMMIT PARTNERS PUBLIC ASSET MANAGEMENT, LLC | $67.7M | 830,247 | 1.19% | 3q | +53.7%+$23.6M |
| Western Financial Corp/CA | $66.9M | 820,239 | 19.58% | 15q | HELD |
| JPMORGAN CHASE & CO | $51.8M | 637,399 | 0.00% | 31q | -6.7%-$3.7M |
| Connor, Clark & Lunn Investment Management Ltd. | $51.0M | 625,569 | 0.10% | 4q | -25.3%-$17.2M |
| TWO SIGMA INVESTMENTS, LP | $47.3M | 580,609 | 0.03% | 2q | +1521.8%+$44.4M |
| Pictet Asset Management Holding SA | $46.7M | 573,419 | 0.04% | 12q | -55.0%-$57.0M |
| BNP PARIBAS FINANCIAL MARKETS | $45.5M | 558,643 | 0.02% | 30q | -14.1%-$7.5M |
| 1832 Asset Management L.P. | $43.9M | 538,500 | 0.02% | new | NEW |
| PRINCIPAL FINANCIAL GROUP INC | $41.9M | 514,658 | 0.02% | 31q | +5.0%+$2.0M |
| VOYA INVESTMENT MANAGEMENT LLC | $39.4M | 483,495 | 0.03% | 31q | -26.3%-$14.1M |
| Balyasny Asset Management L.P. | $38.4M | 470,754 | 0.05% | 4q | +128.1%+$21.5M |
| RENAISSANCE TECHNOLOGIES LLC | $38.2M | 468,921 | 0.05% | 2q | -54.8%-$46.3M |
| FRANKLIN RESOURCES INC | $37.7M | 462,133 | 0.01% | 5q | HELD |
| JANE STREET GROUP, LLC | $35.3M | 196,205 | 0.00% | 28q | +1143.8%+$32.5M |
| D. E. Shaw & Co., Inc. | $35.2M | 431,560 | 0.02% | 6q | -63.5%-$61.3M |
| Nuveen, LLC | $33.9M | 415,883 | 0.01% | 6q | -16.8%-$6.8M |
| MILLENNIUM MANAGEMENT LLC | $33.2M | 329,337 | 0.01% | new | NEW |
| Assenagon Asset Management S.A. | $32.9M | 403,854 | 0.02% | 14q | +587.6%+$28.1M |
| RHUMBLINE ADVISERS | $30.6M | 374,897 | 0.02% | 31q | -7.3%-$2.4M |
| EVENTIDE ASSET MANAGEMENT, LLC | $30.2M | 370,000 | 0.40% | 3q | HELD |
| AMERICAN CENTURY COMPANIES INC | $29.7M | 364,211 | 0.01% | 3q | -44.1%-$23.4M |
| CITIGROUP INC | $26.9M | 264,678 | 0.01% | 31q | +5.2%+$1.3M |
| CITADEL ADVISORS LLC | $26.6M | options only | 0.00% | 31q | OPTIONS |
| Caption Management, LLC | $26.2M | options only | 0.12% | 3q | OPTIONS |
| LPL Financial LLC | $25.3M | 310,761 | 0.01% | 28q | +140.0%+$14.8M |
| Artisan Partners Limited Partnership | $25.3M | 310,706 | 0.04% | new | NEW |
| MARSHALL WACE, LLP | $24.9M | 305,031 | 0.02% | 7q | +69.9%+$10.2M |
| SEI INVESTMENTS CO | $24.5M | 300,619 | 0.02% | 6q | +47.9%+$7.9M |
| NORDEA INVESTMENT MANAGEMENT AB | $23.6M | 284,175 | 0.02% | 22q | -7.3%-$1.8M |
| Russell Investments Group, Ltd. | $23.2M | 284,096 | 0.02% | 30q | +63.3%+$9.0M |
| California Public Employees Retirement System | $20.9M | 256,314 | 0.01% | 2q | HELD |
| Squarepoint Ops LLC | $20.9M | 255,907 | 0.02% | new | NEW |
| ENVESTNET ASSET MANAGEMENT INC | $20.7M | 254,228 | 0.00% | 4q | +280.9%+$15.3M |
| Aberdeen Group plc | $20.5M | 251,968 | 0.03% | 9q | -30.8%-$9.1M |
| Swiss National Bank | $19.5M | 238,900 | 0.01% | 31q | -1.3%-$252.7K |
| Legal & General Group Plc | $19.3M | 237,216 | 0.00% | 31q | +3.5%+$661.8K |
| Privium Fund Management B.V. | $19.1M | 234,222 | 3.51% | 19q | -36.2%-$10.8M |
| ARROWSTREET CAPITAL, LIMITED PARTNERSHIP | $17.8M | 218,133 | 0.01% | 5q | -62.8%-$30.1M |
| Life Cycle Investment Partners Ltd | $17.0M | 209,068 | 0.08% | new | NEW |
| HSBC HOLDINGS PLC | $16.8M | 203,800 | 0.01% | 2q | +34.9%+$4.3M |
| Woodline Partners LP | $16.3M | 200,184 | 0.05% | 14q | HELD |
| Integral Health Asset Management, LLC | $16.3M | 200,000 | 0.64% | 4q | -33.3%-$8.2M |
| AQR CAPITAL MANAGEMENT LLC | $15.8M | 198,842 | 0.01% | 6q | +18.9%+$2.5M |
| MUTUAL OF AMERICA CAPITAL MANAGEMENT LLC | $15.6M | 191,432 | 0.15% | 29q | +3.9%+$581.0K |
| PINNACLE ASSOCIATES LTD | $13.9M | 170,131 | 0.15% | 6q | -3.0%-$434.0K |
| RAYMOND JAMES FINANCIAL INC | $13.8M | 169,913 | 0.00% | 7q | -6.9%-$1.0M |
| WCM INVESTMENT MANAGEMENT, LLC | $13.8M | 171,232 | 0.02% | 3q | HELD |
| SEB Asset Management AB | $12.9M | 158,205 | 0.05% | 2q | HELD |
| Clearbridge Investments, LLC | $12.8M | 157,110 | 0.01% | 6q | -22.4%-$3.7M |
| AMERIPRISE FINANCIAL INC | $12.7M | 155,908 | 0.00% | 29q | -59.2%-$18.4M |
| Affinity Asset Advisors, LLC | $12.2M | 150,000 | 0.55% | 3q | -25.0%-$4.1M |
| DEUTSCHE BANK AG\ | $12.2M | 149,240 | 0.00% | 34q | -42.6%-$9.0M |
| WEALTH EFFECTS LLC | $12.0M | 147,300 | 3.24% | 19q | +2.8%+$326.0K |
| Retirement Systems of Alabama | $11.9M | 145,687 | 0.04% | 2q | -15.1%-$2.1M |
| TORONTO DOMINION BANK | $11.8M | 144,928 | 0.01% | 2q | -3.6%-$436.1K |
| HighTower Advisors, LLC | $11.4M | 140,394 | 0.01% | 31q | -4.1%-$494.6K |
| Ikarian Capital, LLC | $11.3M | 38,278 | 1.21% | 2q | HELD |
| Weiss Asset Management LP | $10.9M | 134,014 | 0.11% | new | NEW |
| BANK OF NOVA SCOTIA | $10.9M | 133,805 | 0.02% | 2q | -1.6%-$175.7K |
| ALLIANCEBERNSTEIN L.P. | $10.9M | 173,265 | 0.00% | 31q | -38.2%-$6.7M |
| PFM Health Sciences, LP | $10.7M | 131,667 | 0.92% | 2q | +104.8%+$5.5M |
| Tetragon Partners GP Ltd | $10.6M | 130,484 | 1.67% | 4q | +2.6%+$267.8K |
| WELLS FARGO & COMPANY/MN | $10.5M | 128,789 | 0.00% | 31q | -59.3%-$15.3M |
| Rhenman & Partners Asset Management AB | $10.4M | 128,000 | 0.98% | 3q | -11.4%-$1.3M |
| VANGUARD ASSET MANAGEMENT, Ltd | $9.7M | 119,102 | 0.01% | 2q | +5.4%+$499.7K |
| Catalyst Funds Management Pty Ltd | $9.6M | 117,600 | 0.54% | new | NEW |
| Universal- Beteiligungs- und Servicegesellschaft mbH | $9.5M | 116,393 | 0.01% | 4q | -3.2%-$313.4K |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | $9.1M | 111,955 | 0.01% | 31q | -30.2%-$4.0M |
Five percent filings
Anyone crossing 5% of a company must say so within days - far sooner than the next quarterly holdings report. A 13D declares an intent to influence the company; a 13G is the passive version. See all activist filings →
| Filed | Form | Filer | % of class |
|---|---|---|---|
| 2026-08-14 | 13G/A | Avoro Capital Advisors LLCwith 1 co-filers | 9.6% |
| 2026-07-31 | 13G/A | Vanguard Portfolio Management | 4.5% |
| 2026-07-27 | 13G/A | BlackRock, Inc. | 10.1% |
Quarter by quarter
Coverage begins with the quarter ending 2018-12-31. Earlier filings exist only as occasional late amendments, too sparse to describe a market, so they are not shown.
| Quarter | Holders | Value | Shares | New | Added | Trimmed | Options |
|---|---|---|---|---|---|---|---|
| Q2 2026 | 477 | $9.8B | 117,766,457 | 117 | 149 | 138 | 2.3% |
| Q1 2026 | 411 | $7.6B | 119,203,841 | 92 | 153 | 102 | 2.1% |
| Q4 2025 | 377 | $7.8B | 114,454,267 | 106 | 107 | 108 | 2.5% |
| Q3 2025 | 284 | $3.9B | 110,891,479 | 61 | 84 | 76 | 1.2% |
| Q2 2025 | 258 | $1.7B | 104,586,133 | 52 | 85 | 72 | 1.0% |
| Q1 2025 | 240 | $1.3B | 101,837,873 | 37 | 75 | 74 | 0.8% |
| Q4 2024 | 245 | $1.8B | 96,441,708 | 28 | 77 | 75 | 1.1% |
| Q3 2024 | 246 | $1.9B | 95,538,907 | 31 | 77 | 79 | 0.6% |
| Q2 2024 | 243 | $2.6B | 96,691,940 | 30 | 79 | 77 | 2.1% |
| Q1 2024 | 246 | $2.9B | 98,963,245 | 36 | 92 | 65 | 1.4% |
| Q4 2023 | 237 | $2.5B | 80,234,461 | 29 | 64 | 78 | 1.1% |
| Q3 2023 | 224 | $2.0B | 73,456,283 | 18 | 73 | 79 | 0.7% |
| Q2 2023 | 241 | $2.5B | 71,070,913 | 41 | 59 | 87 | 1.0% |
| Q1 2023 | 218 | $1.8B | 71,702,355 | 24 | 67 | 76 | 0.9% |
| Q4 2022 | 227 | $2.6B | 63,877,604 | 37 | 70 | 75 | 1.5% |
| Q3 2022 | 274 | $2.4B | 71,640,450 | 26 | 93 | 86 | 1.4% |
| Q2 2022 | 270 | $2.6B | 72,438,337 | 21 | 98 | 91 | 1.3% |
| Q1 2022 | 301 | $3.2B | 69,433,456 | 36 | 111 | 93 | 1.5% |
| Q4 2021 | 311 | $4.7B | 68,429,078 | 41 | 94 | 98 | 3.2% |
| Q3 2021 | 291 | $4.3B | 66,619,841 | 27 | 100 | 96 | 2.3% |
| Q2 2021 | 315 | $5.7B | 67,274,849 | 56 | 88 | 106 | 2.4% |
| Q1 2021 | 286 | $4.6B | 68,549,375 | 25 | 80 | 120 | 1.8% |
| Q4 2020 | 313 | $5.6B | 69,830,621 | 60 | 84 | 106 | 4.6% |
| Q3 2020 | 266 | $3.0B | 68,275,524 | 40 | 75 | 96 | 2.8% |
| Q2 2020 | 250 | $3.1B | 68,961,548 | 39 | 90 | 79 | 3.0% |
| Q1 2020 | 240 | $2.0B | 66,593,144 | 32 | 84 | 85 | 2.6% |
| Q4 2019 | 293 | $4.4B | 66,633,056 | 79 | 81 | 87 | 4.2% |
| Q3 2019 | 225 | $1.9B | 65,836,362 | 41 | 82 | 59 | 2.8% |
| Q2 2019 | 216 | $1.9B | 68,610,467 | 65 | 75 | 51 | 4.5% |
| Q1 2019 | 177 | $1.1B | 59,133,872 | 36 | 52 | 60 | 2.1% |
| Q4 2018 | 160 | $755.4M | 59,638,630 | 2 | 4 | 2 | 2.0% |