ANAPTYSBIO INC (ANAB)
Institutional ownership reported to the SEC as of Q2 2026, across 31 quarters.
206
Reporting holders
$2.1B
Reported value
107.9%
Of shares outstanding
0.5%
Held as options
+9
Holder change
Institutions report 31,394,236 shares against 29,100,902 outstanding. Shares only - option lines are excluded, which is why this can be compared with the company at all. The count comes from the cover page of the company's own most recent report, so it is dated when that was filed rather than at quarter end. Share count carried from an earlier filing (concept 2026-05-07); over 100% because an adviser and a sub-adviser can both report the same shares, and both are counted.
Options share is the part of reported value carried in derivative lines rather than shares. A high figure means institutions are expressing a view on this security without owning much of it.
Holders
| Filer | Value | Shares | Their book | Held | Change |
|---|---|---|---|---|---|
| EcoR1 Capital, LLC | $531.9M | 7,880,094 | 25.86% | 27q | HELD |
| BlackRock, Inc. | $124.5M | 1,844,049 | 0.00% | 8q | +9.7%+$11.0M |
| Palo Alto Investors LP | $122.2M | 1,810,467 | 5.63% | 24q | +183.7%+$79.1M |
| TANG CAPITAL MANAGEMENT LLC | $89.8M | 1,330,879 | 4.08% | 27q | HELD |
| STATE STREET CORP | $86.8M | 1,286,194 | 0.00% | 31q | +29.6%+$19.8M |
| VANGUARD CAPITAL MANAGEMENT LLC | $61.2M | 906,233 | 0.00% | 2q | +6.2%+$3.6M |
| Affinity Asset Advisors, LLC | $55.8M | 826,109 | 2.52% | 3q | -12.1%-$7.7M |
| MILLENNIUM MANAGEMENT LLC | $55.5M | 807,316 | 0.02% | 17q | +69.8%+$22.8M |
| Sanofi | $55.5M | 821,917 | 10.39% | 7q | HELD |
| Woodline Partners LP | $48.4M | 717,014 | 0.15% | 22q | +108.3%+$25.2M |
| 683 Capital Management, LLC | $44.6M | 660,000 | 2.19% | 6q | +5.6%+$2.4M |
| GEODE CAPITAL MANAGEMENT, LLC | $43.1M | 637,873 | 0.00% | 31q | +22.6%+$7.9M |
| GOLDMAN SACHS GROUP INC | $39.4M | 584,070 | 0.00% | 31q | +75.5%+$17.0M |
| First Light Asset Management, LLC | $39.3M | 582,004 | 2.39% | 13q | +2.9%+$1.1M |
| D. E. Shaw & Co., Inc. | $36.4M | 539,666 | 0.02% | 27q | -6.8%-$2.7M |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $35.6M | 527,858 | 0.00% | 2q | +1.5%+$539.2K |
| Apis Capital Advisors, LLC | $33.5M | 497,000 | 3.27% | 2q | +108.8%+$17.5M |
| Sofinnova Investments, Inc. | $33.3M | 493,536 | 1.72% | 7q | +98.8%+$16.6M |
| ARROWSTREET CAPITAL, LIMITED PARTNERSHIP | $33.0M | 488,651 | 0.01% | 5q | -0.7%-$234.2K |
| Nuveen, LLC | $28.4M | 420,664 | 0.01% | 6q | +33.1%+$7.1M |
| BANK OF AMERICA CORP /DE/ | $28.2M | 417,812 | 0.00% | 31q | -16.6%-$5.6M |
| CITADEL ADVISORS LLC | $27.9M | 394,373 | 0.00% | 31q | +68.9%+$11.4M |
| FEDERATED HERMES, INC. | $26.4M | 391,667 | 0.04% | 31q | +7.6%+$1.9M |
| Squarepoint Ops LLC | $21.9M | 324,446 | 0.02% | 5q | +21.2%+$3.8M |
| TWO SIGMA INVESTMENTS, LP | $17.8M | 262,995 | 0.01% | 15q | -43.5%-$13.6M |
| FIRST TRUST ADVISORS LP | $17.5M | 258,989 | 0.01% | new | NEW |
| MORGAN STANLEY | $17.4M | 257,091 | 0.00% | 35q | -74.1%-$49.7M |
| Coppell Advisory Solutions LLC | $16.6M | 3,638 | 1.37% | new | NEW |
| FMR LLC | $16.2M | 240,511 | 0.00% | 31q | -49.1%-$15.7M |
| Qube Research & Technologies Ltd | $15.4M | 228,777 | 0.01% | 3q | -10.2%-$1.8M |
| HSBC HOLDINGS PLC | $14.9M | 216,949 | 0.01% | 2q | +72.6%+$6.3M |
| Empowered Funds, LLC | $13.9M | 206,010 | 0.07% | new | NEW |
| NORTHERN TRUST CORP | $13.7M | 202,767 | 0.00% | 31q | +10.5%+$1.3M |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $13.7M | 202,305 | 0.00% | 31q | +5.0%+$649.2K |
| Sixth Street Partners Management Company, L.P. | $13.7M | 202,305 | 0.00% | new | NEW |
| Invesco Ltd. | $13.6M | 202,056 | 0.00% | 13q | +66.8%+$5.5M |
| DIMENSIONAL FUND ADVISORS LP | $12.5M | 185,444 | 0.00% | new | NEW |
| Greenhaven Road Investment Management, L.P. | $11.5M | 171,059 | 7.50% | new | NEW |
| VICTORY CAPITAL MANAGEMENT INC | $11.4M | 169,227 | 0.01% | 12q | +56.4%+$4.1M |
| MACKENZIE FINANCIAL CORP | $10.2M | 150,979 | 0.01% | 3q | +347.7%+$7.9M |
| UBS Group AG | $9.9M | 146,832 | 0.00% | 31q | +84.3%+$4.5M |
| VANGUARD FIDUCIARY TRUST CO | $9.9M | 146,724 | 0.00% | 2q | +8.6%+$785.8K |
| Connor, Clark & Lunn Investment Management Ltd. | $9.5M | 141,026 | 0.02% | 3q | -11.1%-$1.2M |
| Ensign Peak Advisors, Inc | $7.2M | 107,096 | 0.01% | 20q | -57.4%-$9.7M |
| FRANKLIN RESOURCES INC | $7.2M | 106,949 | 0.00% | 2q | +62.5%+$2.8M |
| CITIGROUP INC | $6.7M | 99,114 | 0.00% | 31q | +35.0%+$1.7M |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $6.5M | options only | 0.00% | 31q | OPTIONS |
| NOMURA ASSET MANAGEMENT INTERNATIONAL INC. | $6.3M | 93,732 | 0.01% | 3q | HELD |
| PRUDENTIAL FINANCIAL INC | $5.8M | 85,932 | 0.01% | 2q | +34.2%+$1.5M |
| DZ BANK AG Deutsche Zentral Genossenschafts Bank, Frankfurt am Main | $5.7M | 83,942 | 0.00% | new | NEW |
| JPMORGAN CHASE & CO | $5.3M | 80,236 | 0.00% | 31q | +589.0%+$4.5M |
| Granahan Investment Management, LLC | $5.1M | 75,962 | 0.18% | 7q | +14.8%+$660.1K |
| Irenic Capital Management LP | $4.8M | 70,447 | 0.23% | new | NEW |
| Eversept Partners, LP | $4.7M | 69,983 | 0.25% | 3q | +158.3%+$2.9M |
| JACOBS LEVY EQUITY MANAGEMENT, INC | $4.2M | 62,336 | 0.02% | 14q | +117.8%+$2.3M |
| STATE OF WISCONSIN INVESTMENT BOARD | $4.2M | 61,753 | 0.01% | 3q | +123.6%+$2.3M |
| RENAISSANCE TECHNOLOGIES LLC | $3.9M | 58,300 | 0.01% | 14q | -35.9%-$2.2M |
| VOLORIDGE INVESTMENT MANAGEMENT, LLC | $3.9M | 57,555 | 0.02% | 4q | -27.1%-$1.4M |
| Bank of New York Mellon Corp | $3.8M | 56,401 | 0.00% | 31q | +10.3%+$356.8K |
| DEUTSCHE BANK AG\ | $3.2M | 46,884 | 0.00% | 34q | -9.9%-$347.9K |
| AQR CAPITAL MANAGEMENT LLC | $3.1M | 46,323 | 0.00% | 8q | +42.7%+$935.3K |
| MARSHALL WACE, LLP | $3.0M | 43,822 | 0.00% | 2q | -35.6%-$1.6M |
| Bleakley Financial Group, LLC | $2.9M | 42,761 | 0.04% | 5q | -0.8%-$24.2K |
| WELLINGTON MANAGEMENT GROUP LLP | $2.8M | 41,796 | 0.00% | 10q | -10.8%-$343.2K |
| WELLS FARGO & COMPANY/MN | $2.8M | 41,707 | 0.00% | 14q | -37.2%-$1.7M |
| HighMark Wealth Management LLC | $2.7M | 39,716 | 0.90% | 6q | -57.8%-$3.7M |
| CAPITAL FUND MANAGEMENT S.A. | $2.6M | 39,142 | 0.01% | new | NEW |
| Trexquant Investment LP | $2.4M | 35,404 | 0.01% | 12q | -58.4%-$3.4M |
| Atom Investors LP | $2.3M | 33,917 | 0.20% | new | NEW |
| Swiss National Bank | $2.1M | 31,700 | 0.00% | 31q | +14.9%+$276.8K |
| Voleon Capital Management LP | $2.1M | 31,425 | 0.04% | new | NEW |
| Tidal Investments LLC | $2.1M | 31,270 | 0.00% | 2q | -14.0%-$343.0K |
| Tema ETFs LLC | $2.1M | 31,270 | 0.07% | 5q | +0.6%+$13.6K |
| Moody Aldrich Partners LLC | $2.1M | 30,926 | 0.38% | 6q | -21.6%-$575.7K |
| Aquatic Capital Management LLC | $2.1M | 30,813 | 0.07% | new | NEW |
| SummitTX Capital, L.P. | $1.9M | 28,779 | 0.05% | new | NEW |
| ALLIANCEBERNSTEIN L.P. | $1.8M | 32,820 | 0.00% | 31q | +4.8%+$83.2K |
| RHUMBLINE ADVISERS | $1.8M | 26,346 | 0.00% | 31q | +10.5%+$168.6K |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | $1.6M | 23,310 | 0.00% | 14q | -24.1%-$500.6K |
| BURNEY CO/ | $1.5M | 22,557 | 0.04% | new | NEW |
| Rafferty Asset Management, LLC | $1.5M | 21,864 | 0.00% | 10q | -19.8%-$363.5K |
| XTX Topco Ltd | $1.4M | 21,411 | 0.02% | 5q | -57.6%-$2.0M |
| HUSSMAN STRATEGIC ADVISORS, INC. | $1.4M | 21,000 | 0.33% | 2q | HELD |
| TUDOR INVESTMENT CORP ET AL | $1.4M | 20,019 | 0.00% | 8q | +303.4%+$1.0M |
| CREDIT AGRICOLE S A | $1.4M | 20,000 | 0.00% | 3q | HELD |
| MARTINGALE ASSET MANAGEMENT L P | $1.3M | 19,942 | 0.03% | 2q | -29.1%-$553.5K |
| Creative Planning | $1.3M | 18,773 | 0.00% | 6q | +11.5%+$130.7K |
| Y-Intercept (Hong Kong) Ltd | $1.2M | 18,468 | 0.02% | 3q | -18.6%-$285.7K |
| LOS ANGELES CAPITAL MANAGEMENT LLC | $1.2M | 17,536 | 0.00% | 5q | +12.0%+$126.4K |
| Diametric Capital, LP | $1.1M | 16,868 | 0.12% | new | NEW |
| CANADA PENSION PLAN INVESTMENT BOARD | $1.1M | 16,500 | 0.00% | 2q | +10.7%+$108.0K |
| Legal & General Group Plc | $1.1M | 16,415 | 0.00% | 31q | +18.7%+$174.4K |
| SIMPLEX TRADING, LLC | $1.1M | 1,267 | 0.00% | 8q | HELD |
| Russell Investments Group, Ltd. | $1.1M | 16,301 | 0.00% | 5q | +22.7%+$203.4K |
| MASSACHUSETTS FINANCIAL SERVICES CO /MA/ | $1.1M | 15,870 | 0.00% | new | NEW |
| Verition Fund Management LLC | $1.0M | 15,000 | 0.00% | new | NEW |
| Cresset Asset Management, LLC | $972.8K | 14,412 | 0.00% | 6q | +3.9%+$36.7K |
| Vanguard Global Advisers, LLC | $939.5K | 13,919 | 0.00% | 2q | +18.4%+$146.1K |
| Zurcher Kantonalbank (Zurich Cantonalbank) | $904.8K | 13,405 | 0.00% | 31q | +39.6%+$256.9K |
| Brevan Howard Capital Management LP | $899.7K | 13,329 | 0.01% | 2q | +20.9%+$155.3K |
Five percent filings
Anyone crossing 5% of a company must say so within days - far sooner than the next quarterly holdings report. A 13D declares an intent to influence the company; a 13G is the passive version. See all activist filings →
| Filed | Form | Filer | % of class |
|---|---|---|---|
| 2026-08-14 | 13G/A | Sirenia Capital Management LPwith 1 co-filers | 5.0% |
Quarter by quarter
Coverage begins with the quarter ending 2018-12-31. Earlier filings exist only as occasional late amendments, too sparse to describe a market, so they are not shown.
| Quarter | Holders | Value | Shares | New | Added | Trimmed | Options |
|---|---|---|---|---|---|---|---|
| Q2 2026 | 206 | $2.1B | 31,394,236 | 45 | 67 | 62 | 0.5% |
| Q1 2026 | 197 | $1.6B | 28,203,939 | 43 | 52 | 61 | 0.1% |
| Q4 2025 | 169 | $1.5B | 29,450,300 | 32 | 47 | 59 | 2.9% |
| Q3 2025 | 155 | $1.0B | 31,674,032 | 31 | 40 | 53 | 2.4% |
| Q2 2025 | 138 | $806.7M | 35,986,127 | 24 | 40 | 48 | 1.0% |
| Q1 2025 | 143 | $736.2M | 39,047,490 | 39 | 39 | 39 | 1.4% |
| Q4 2024 | 134 | $491.6M | 33,219,925 | 16 | 47 | 34 | 10.5% |
| Q3 2024 | 152 | $1.2B | 32,679,169 | 39 | 59 | 29 | 5.6% |
| Q2 2024 | 125 | $724.7M | 28,870,602 | 21 | 38 | 44 | 0.2% |
| Q1 2024 | 123 | $682.9M | 30,207,684 | 21 | 35 | 36 | 0.4% |
| Q4 2023 | 109 | $652.7M | 30,355,315 | 11 | 30 | 38 | 0.4% |
| Q3 2023 | 109 | $541.8M | 30,066,606 | 13 | 31 | 34 | 0.4% |
| Q2 2023 | 107 | $586.1M | 28,710,526 | 12 | 37 | 33 | 0.4% |
| Q1 2023 | 97 | $641.6M | 29,357,933 | 12 | 28 | 32 | 0.4% |
| Q4 2022 | 96 | $927.8M | 29,864,521 | 11 | 23 | 30 | 0.2% |
| Q3 2022 | 113 | $836.8M | 32,557,662 | 9 | 36 | 35 | 0.7% |
| Q2 2022 | 125 | $637.9M | 31,164,476 | 19 | 36 | 39 | 0.8% |
| Q1 2022 | 130 | $735.7M | 29,691,314 | 14 | 30 | 49 | 0.0% |
| Q4 2021 | 137 | $967.8M | 27,800,140 | 24 | 33 | 40 | 0.2% |
| Q3 2021 | 127 | $749.8M | 27,612,413 | 15 | 29 | 41 | 0.1% |
| Q2 2021 | 121 | $725.2M | 27,831,902 | 14 | 25 | 51 | 0.5% |
| Q1 2021 | 122 | $644.2M | 29,170,732 | 13 | 38 | 39 | 2.4% |
| Q4 2020 | 134 | $608.3M | 28,001,385 | 24 | 35 | 44 | 1.0% |
| Q3 2020 | 129 | $430.8M | 29,117,638 | 22 | 27 | 49 | 0.3% |
| Q2 2020 | 120 | $676.8M | 30,112,042 | 25 | 29 | 45 | 0.6% |
| Q1 2020 | 114 | $448.0M | 31,285,036 | 17 | 42 | 37 | 1.3% |
| Q4 2019 | 122 | $484.5M | 28,629,420 | 37 | 47 | 19 | 4.0% |
| Q3 2019 | 122 | $1.1B | 29,110,158 | 17 | 49 | 30 | 3.7% |
| Q2 2019 | 129 | $1.7B | 30,290,350 | 24 | 61 | 21 | 2.1% |
| Q1 2019 | 129 | $2.2B | 29,116,728 | 25 | 51 | 26 | 1.4% |
| Q4 2018 | 122 | $1.9B | 29,225,022 | 3 | 4 | 2 | 1.0% |