AGIOS PHARMACEUTICALS INC (AGIO)
Institutional ownership reported to the SEC as of Q2 2026, across 31 quarters.
224
Reporting holders
$2.7B
Reported value
115.0%
Of shares outstanding
5.6%
Held as options
+4
Holder change
Institutions report 68,663,907 shares against 59,701,882 outstanding. Shares only - option lines are excluded, which is why this can be compared with the company at all. The count comes from the cover page of the company's own most recent report, so it is dated when that was filed rather than at quarter end. Over 100% because an adviser and a sub-adviser can both report the same shares, and both are counted.
Options share is the part of reported value carried in derivative lines rather than shares. A high figure means institutions are expressing a view on this security without owning much of it.
Holders
| Filer | Value | Shares | Their book | Held | Change |
|---|---|---|---|---|---|
| Lynx1 Capital Management LP | $253.0M | 6,817,874 | 18.43% | 3q | +161.1%+$156.1M |
| BlackRock, Inc. | $239.6M | 6,455,997 | 0.00% | 8q | +12.2%+$26.0M |
| FARALLON CAPITAL MANAGEMENT, L.L.C. | $219.6M | 5,917,400 | 1.01% | 27q | +4.1%+$8.7M |
| ARMISTICE CAPITAL, LLC | $193.3M | 2,400,000 | 2.37% | 16q | -11.6%-$25.5M |
| STATE STREET CORP | $131.1M | 3,533,633 | 0.00% | 31q | +5.0%+$6.3M |
| D. E. Shaw & Co., Inc. | $115.3M | 3,107,005 | 0.05% | 31q | +15.9%+$15.8M |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $107.6M | 2,898,197 | 0.00% | 2q | +11.0%+$10.7M |
| VANGUARD CAPITAL MANAGEMENT LLC | $99.5M | 2,681,845 | 0.00% | 2q | +1.9%+$1.8M |
| Erste Asset Management GmbH | $82.0M | 2,154,900 | 0.64% | 31q | -20.3%-$20.9M |
| NOMURA ASSET MANAGEMENT INTERNATIONAL INC. | $78.3M | 2,110,809 | 0.12% | 3q | +41.2%+$22.9M |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $62.5M | 1,375,558 | 0.00% | 31q | +2.3%+$1.4M |
| GEODE CAPITAL MANAGEMENT, LLC | $58.4M | 1,574,268 | 0.00% | 31q | +7.2%+$3.9M |
| ADAR1 Capital Management, LLC | $47.8M | 1,288,053 | 2.19% | 6q | +815.6%+$42.6M |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | $47.5M | 1,280,044 | 0.05% | 31q | -19.0%-$11.2M |
| DIMENSIONAL FUND ADVISORS LP | $46.3M | 1,248,738 | 0.01% | 31q | +8.4%+$3.6M |
| GOLDMAN SACHS GROUP INC | $42.7M | 1,150,932 | 0.00% | 31q | +42.8%+$12.8M |
| UBS Group AG | $36.6M | 985,831 | 0.00% | 31q | +643.8%+$31.7M |
| MORGAN STANLEY | $35.7M | 963,256 | 0.00% | 35q | HELD |
| CITADEL ADVISORS LLC | $33.9M | 732,687 | 0.00% | 31q | +18.2%+$5.2M |
| Nuveen, LLC | $32.4M | 873,560 | 0.01% | 6q | +20.9%+$5.6M |
| ARROWSTREET CAPITAL, LIMITED PARTNERSHIP | $30.1M | 810,530 | 0.01% | 2q | +223.6%+$20.8M |
| Foresite Capital Management VI LLC | $29.1M | 785,000 | 4.53% | 3q | +49.5%+$9.6M |
| JANE STREET GROUP, LLC | $27.7M | 492,598 | 0.00% | 15q | -28.1%-$10.8M |
| AQR CAPITAL MANAGEMENT LLC | $25.4M | 684,340 | 0.01% | 10q | +1779.5%+$24.0M |
| Parkman Healthcare Partners LLC | $24.8M | 669,046 | 2.54% | 4q | +65.8%+$9.9M |
| Palo Alto Investors LP | $23.8M | 640,803 | 1.10% | 6q | +200.0%+$15.9M |
| SCS Capital Management LLC | $22.7M | 612,850 | 0.21% | 6q | HELD |
| Qube Research & Technologies Ltd | $22.2M | 597,638 | 0.02% | 3q | +218.5%+$15.2M |
| NORTHERN TRUST CORP | $20.6M | 554,709 | 0.00% | 31q | +8.9%+$1.7M |
| Defilade Capital Management, L.P. | $20.3M | 546,848 | 2.72% | new | NEW |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $20.0M | 538,128 | 0.00% | 31q | +12.8%+$2.3M |
| Sixth Street Partners Management Company, L.P. | $20.0M | 538,128 | 0.00% | new | NEW |
| TWO SIGMA INVESTMENTS, LP | $19.9M | 536,380 | 0.01% | 4q | +113.2%+$10.6M |
| Rock Springs Capital Management LP | $19.8M | 532,563 | 0.96% | 30q | -33.4%-$9.9M |
| Schonfeld Strategic Advisors LLC | $19.3M | 520,083 | 0.07% | 2q | +160.0%+$11.9M |
| BANK OF AMERICA CORP /DE/ | $18.8M | 507,869 | 0.00% | 31q | HELD |
| Point72 Asset Management, L.P. | $18.8M | 506,344 | 0.02% | 4q | HELD |
| Legal & General Group Plc | $16.1M | 434,719 | 0.00% | 31q | +2.5%+$400.9K |
| VANGUARD FIDUCIARY TRUST CO | $14.7M | 395,868 | 0.00% | 2q | +3.6%+$513.9K |
| PANAGORA ASSET MANAGEMENT INC | $13.9M | 373,931 | 0.04% | 3q | +56.8%+$5.0M |
| KENNEDY CAPITAL MANAGEMENT LLC | $13.9M | 373,230 | 0.25% | 10q | +35.5%+$3.6M |
| JPMORGAN CHASE & CO | $13.8M | 359,756 | 0.00% | 31q | +137.4%+$8.0M |
| Connor, Clark & Lunn Investment Management Ltd. | $13.3M | 359,550 | 0.03% | 9q | -20.1%-$3.4M |
| Squarepoint Ops LLC | $11.9M | 321,138 | 0.01% | 3q | +53.7%+$4.2M |
| GROUP ONE TRADING LLC | $11.5M | 151,994 | 0.02% | 3q | -12.3%-$1.6M |
| Ensign Peak Advisors, Inc | $11.0M | 297,630 | 0.02% | 19q | +2165.1%+$10.6M |
| BNP PARIBAS FINANCIAL MARKETS | $10.0M | 269,383 | 0.00% | 31q | -17.7%-$2.2M |
| Tetragon Partners GP Ltd | $9.5M | 205,579 | 1.49% | 3q | +24.7%+$1.9M |
| ALGERT GLOBAL LLC | $9.2M | 248,007 | 0.11% | 10q | -53.8%-$10.7M |
| Assenagon Asset Management S.A. | $7.7M | 207,910 | 0.00% | 4q | +209.6%+$5.2M |
| Bank of New York Mellon Corp | $7.4M | 198,685 | 0.00% | 31q | +6.4%+$441.4K |
| Jump Financial, LLC | $6.8M | 182,773 | 0.05% | new | NEW |
| BOOTHBAY FUND MANAGEMENT, LLC | $6.5M | 149,886 | 0.09% | 11q | HELD |
| Invesco Ltd. | $6.2M | 168,153 | 0.00% | 31q | +11.0%+$620.6K |
| FIRST TRUST ADVISORS LP | $6.1M | 165,587 | 0.00% | new | NEW |
| Ishara Investments LP | $6.1M | 164,000 | 4.47% | new | NEW |
| CITIGROUP INC | $5.8M | 89,167 | 0.00% | 31q | +421.6%+$4.7M |
| MARSHALL WACE, LLP | $5.2M | 138,800 | 0.00% | 10q | -69.0%-$11.5M |
| AMERICAN CENTURY COMPANIES INC | $5.0M | 134,512 | 0.00% | 16q | +11.9%+$529.2K |
| Man Group plc | $4.6M | 124,466 | 0.01% | 2q | -13.7%-$735.9K |
| ArrowMark Colorado Holdings LLC | $4.4M | 117,714 | 0.18% | 31q | -70.8%-$10.6M |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | $4.3M | 116,909 | 0.00% | 31q | +5.6%+$231.2K |
| Pictet Asset Management Holding SA | $4.2M | 111,861 | 0.00% | 12q | -13.2%-$643.7K |
| Swiss National Bank | $4.1M | 111,660 | 0.00% | 31q | +2.6%+$103.9K |
| CAPITAL FUND MANAGEMENT S.A. | $3.9M | 104,080 | 0.02% | 3q | -19.6%-$944.5K |
| Universal- Beteiligungs- und Servicegesellschaft mbH | $3.7M | 99,726 | 0.01% | 6q | +64.4%+$1.4M |
| Knott David M Jr | $3.5M | 95,058 | 1.86% | 3q | +2.1%+$74.2K |
| Trexquant Investment LP | $3.5M | 93,539 | 0.02% | 3q | +24.2%+$676.9K |
| Jain Global LLC | $3.4M | 91,647 | 0.01% | new | NEW |
| Caligan Partners LP | $3.3M | options only | 0.16% | 15q | OPTIONS |
| Caption Management, LLC | $3.3M | 39,249 | 0.02% | 10q | +217.8%+$2.3M |
| RHUMBLINE ADVISERS | $2.9M | 79,441 | 0.00% | 31q | +8.3%+$225.3K |
| Campbell & CO Investment Adviser LLC | $2.7M | 73,095 | 0.14% | new | NEW |
| Exome Asset Management LLC | $2.6M | 70,500 | 1.61% | 3q | -43.6%-$2.0M |
| Edgestream Partners, L.P. | $2.6M | 70,195 | 0.08% | 3q | -51.2%-$2.7M |
| Russell Investments Group, Ltd. | $2.5M | 66,856 | 0.00% | 26q | +68.4%+$1.0M |
| TUDOR INVESTMENT CORP ET AL | $2.4M | 65,779 | 0.00% | 3q | +13.1%+$283.1K |
| DEUTSCHE BANK AG\ | $2.3M | 62,228 | 0.00% | 34q | +23.5%+$439.5K |
| ALPS ADVISORS INC | $2.2M | 60,059 | 0.01% | 23q | +25.9%+$458.6K |
| Seven Fleet Capital Management LP | $2.1M | 56,900 | 0.35% | 3q | -72.8%-$5.7M |
| ALLIANCEBERNSTEIN L.P. | $2.1M | 61,864 | 0.00% | 31q | +0.6%+$12.5K |
| Rafferty Asset Management, LLC | $2.1M | 55,580 | 0.00% | 30q | -45.9%-$1.8M |
| Engineers Gate Manager LP | $2.0M | 53,912 | 0.03% | 3q | +86.4%+$927.5K |
| WELLS FARGO & COMPANY/MN | $2.0M | 53,240 | 0.00% | 31q | +16.9%+$286.3K |
| VANGUARD ASSET MANAGEMENT, Ltd | $1.9M | 52,050 | 0.00% | 2q | -11.3%-$244.9K |
| XTX Topco Ltd | $1.9M | 50,366 | 0.02% | 3q | -68.7%-$4.1M |
| SIMPLEX TRADING, LLC | $1.9M | options only | 0.00% | 31q | OPTIONS |
| DZ BANK AG Deutsche Zentral Genossenschafts Bank, Frankfurt am Main | $1.8M | 49,764 | 0.00% | new | NEW |
| BARCLAYS PLC | $1.8M | 48,300 | 0.00% | 31q | -7.9%-$153.6K |
| Quantinno Capital Management LP | $1.6M | 43,514 | 0.00% | 3q | +57.7%+$590.9K |
| MARTINGALE ASSET MANAGEMENT L P | $1.6M | 43,009 | 0.04% | 2q | +20.1%+$267.0K |
| MERCER GLOBAL ADVISORS INC /ADV | $1.6M | 42,590 | 0.00% | new | NEW |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | $1.5M | 41,455 | 0.00% | 9q | -1.5%-$22.9K |
| IEQ CAPITAL, LLC | $1.5M | 40,404 | 0.01% | new | NEW |
| Virtus Investment Advisers, LLC | $1.5M | 39,473 | 0.34% | 6q | +27.5%+$316.0K |
| FMR LLC | $1.4M | 39,072 | 0.00% | 31q | +328.4%+$1.1M |
| Aquatic Capital Management LLC | $1.4M | 38,627 | 0.05% | 3q | +241.2%+$1.0M |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | $1.4M | 37,727 | 0.00% | 21q | -24.6%-$457.2K |
| SEI INVESTMENTS CO | $1.3M | 35,089 | 0.00% | 9q | -44.8%-$1.1M |
| EDGEWOOD MANAGEMENT LLC | $1.3M | 35,000 | 0.01% | 16q | HELD |
Five percent filings
Anyone crossing 5% of a company must say so within days - far sooner than the next quarterly holdings report. A 13D declares an intent to influence the company; a 13G is the passive version. See all activist filings →
| Filed | Form | Filer | % of class |
|---|---|---|---|
| 2026-08-03 | 13G/A | Farallon Capital Management, L.L.C.with 28 co-filers | 9.9% |
| 2026-07-02 | 13G | D. E. Shaw & Co., L.P.with 1 co-filers | 5.1% |
Quarter by quarter
Coverage begins with the quarter ending 2018-12-31. Earlier filings exist only as occasional late amendments, too sparse to describe a market, so they are not shown.
| Quarter | Holders | Value | Shares | New | Added | Trimmed | Options |
|---|---|---|---|---|---|---|---|
| Q2 2026 | 224 | $2.7B | 68,663,907 | 34 | 91 | 54 | 5.6% |
| Q1 2026 | 220 | $2.1B | 59,933,283 | 27 | 74 | 79 | 6.7% |
| Q4 2025 | 222 | $1.8B | 58,155,342 | 54 | 71 | 62 | 10.2% |
| Q3 2025 | 214 | $2.6B | 60,167,603 | 41 | 62 | 64 | 6.3% |
| Q2 2025 | 203 | $1.9B | 57,492,834 | 24 | 79 | 69 | 1.0% |
| Q1 2025 | 203 | $1.7B | 55,841,761 | 31 | 66 | 70 | 1.3% |
| Q4 2024 | 209 | $1.8B | 55,158,775 | 30 | 75 | 62 | 1.1% |
| Q3 2024 | 192 | $2.5B | 54,731,714 | 23 | 64 | 67 | 1.5% |
| Q2 2024 | 189 | $2.4B | 55,302,810 | 43 | 42 | 75 | 0.9% |
| Q1 2024 | 172 | $1.8B | 62,174,120 | 41 | 55 | 49 | 1.5% |
| Q4 2023 | 154 | $1.3B | 59,188,908 | 22 | 56 | 36 | 0.8% |
| Q3 2023 | 133 | $1.4B | 55,573,495 | 9 | 45 | 46 | 1.2% |
| Q2 2023 | 137 | $1.6B | 55,886,563 | 12 | 59 | 41 | 1.0% |
| Q1 2023 | 137 | $1.3B | 55,010,977 | 14 | 49 | 46 | 1.0% |
| Q4 2022 | 131 | $1.4B | 50,042,072 | 18 | 47 | 36 | 1.2% |
| Q3 2022 | 162 | $1.7B | 58,329,207 | 29 | 52 | 51 | 1.8% |
| Q2 2022 | 151 | $1.3B | 59,216,301 | 21 | 58 | 45 | 0.9% |
| Q1 2022 | 152 | $1.8B | 60,097,087 | 18 | 40 | 55 | 1.1% |
| Q4 2021 | 157 | $2.0B | 59,362,514 | 25 | 45 | 57 | 1.2% |
| Q3 2021 | 165 | $2.8B | 60,901,103 | 16 | 42 | 66 | 1.1% |
| Q2 2021 | 188 | $3.7B | 65,931,593 | 37 | 50 | 62 | 1.7% |
| Q1 2021 | 181 | $3.4B | 65,256,350 | 16 | 57 | 66 | 1.7% |
| Q4 2020 | 202 | $2.9B | 65,293,976 | 31 | 62 | 70 | 2.5% |
| Q3 2020 | 209 | $2.3B | 65,866,073 | 32 | 77 | 55 | 0.8% |
| Q2 2020 | 216 | $3.7B | 67,941,984 | 46 | 63 | 59 | 1.3% |
| Q1 2020 | 195 | $2.5B | 69,638,267 | 30 | 55 | 67 | 2.1% |
| Q4 2019 | 203 | $3.4B | 69,995,847 | 39 | 88 | 47 | 1.7% |
| Q3 2019 | 184 | $2.1B | 62,184,956 | 29 | 68 | 52 | 2.1% |
| Q2 2019 | 188 | $3.1B | 61,148,193 | 27 | 66 | 58 | 2.7% |
| Q1 2019 | 204 | $4.1B | 60,134,638 | 41 | 74 | 48 | 2.0% |
| Q4 2018 | 194 | $2.8B | 58,608,870 | 2 | 5 | 2 | 2.2% |