# VYNE THERAPEUTICS INC (VYNE)

> Institutional ownership reported to the SEC as of Q2 2026, from Form 13F filings. Source: https://holderbook.com/stocks/VYNE/

- Reporting holders: 47
- Reported value: $12.1M
- Held through calls: 0.0%
- Held through puts: 0.0%

A 13F reports long US equity positions only. Shorts, bonds, foreign listings and cash are not visible here, and positions are disclosed up to 45 days after the quarter ends.

## Largest holders

| Manager | Value | Shares | Share of their book | Quarters held |
|---|---|---|---|---|
| [Nantahala Capital Management, LLC](https://holderbook.com/funds/1472322-nantahala-capital-management-llc/) | $2.6M | 4,000,000 | 0.0% | 3 |
| [Lynx1 Capital Management LP](https://holderbook.com/funds/1910456-lynx1-capital-management-lp/) | $2.1M | 3,257,400 | 0.2% | 2 |
| [ADAR1 Capital Management, LLC](https://holderbook.com/funds/1940272-adar1-capital-management-llc/) | $1.9M | 2,950,000 | 0.1% | 3 |
| [Shay Capital LLC](https://holderbook.com/funds/1723643-shay-capital-llc/) | $947.8K | 1,456,651 | 0.1% | 4 |
| [Deeter Investments LLP](https://holderbook.com/funds/1675711-deeter-investments-llp/) | $650.7K | 1,000,000 | 0.1% | 3 |
| [T3 Companies, LLC](https://holderbook.com/funds/2052441-t3-companies-llc/) | $614.9K | 945,000 | 0.7% | 3 |
| [CITADEL ADVISORS LLC](https://holderbook.com/funds/1423053-citadel-advisors-llc/) | $609.6K | 936,914 | 0.0% | 3 |
| [BRAIDWELL LP](https://holderbook.com/funds/1920938-braidwell-lp/) | $596.1K | 916,077 | 0.0% | 2 |
| [KVP Capital Advisors, LP](https://holderbook.com/funds/1858198-kvp-capital-advisors-lp/) | $325.7K | 500,551 | 0.2% | 3 |
| [TWO SIGMA INVESTMENTS, LP](https://holderbook.com/funds/1179392-two-sigma-investments-lp/) | $285.5K | 438,818 | 0.0% | 4 |
| [ACADIAN ASSET MANAGEMENT LLC](https://holderbook.com/funds/916542-acadian-asset-management-llc/) | $248.0K | 381,797 | 0.0% | 5 |
| [Ikarian Capital, LLC](https://holderbook.com/funds/1778253-ikarian-capital-llc/) | $172.4K | 264,912 | 0.0% | 5 |
| [VANGUARD CAPITAL MANAGEMENT LLC](https://holderbook.com/funds/2100119-vanguard-capital-management-llc/) | $172.2K | 264,557 | 0.0% | 2 |
| [GEODE CAPITAL MANAGEMENT, LLC](https://holderbook.com/funds/1214717-geode-capital-management-llc/) | $168.0K | 258,203 | 0.0% | 14 |
| [VANGUARD FIDUCIARY TRUST CO](https://holderbook.com/funds/933478-vanguard-fiduciary-trust-co/) | $119.4K | 183,443 | 0.0% | 2 |
| [SUSQUEHANNA INTERNATIONAL GROUP, LLP](https://holderbook.com/funds/1446194-susquehanna-international-group-llp/) | $77.4K | 118,957 | 0.0% | 14 |
| [Rangeley Capital, LLC](https://holderbook.com/funds/1517796-rangeley-capital-llc/) | $73.6K | 113,064 | 0.1% | 4 |
| [XTX Topco Ltd](https://holderbook.com/funds/1828301-xtx-topco-ltd/) | $51.2K | 78,721 | 0.0% | 3 |
| [GSA CAPITAL PARTNERS LLP](https://holderbook.com/funds/1362033-gsa-capital-partners-llp/) | $47.0K | 71,533 | 0.0% | 1 |
| [SUPERSTRING CAPITAL MANAGEMENT LP](https://holderbook.com/funds/1931118-superstring-capital-management-lp/) | $39.9K | 61,269 | 0.0% | 1 |
| [UBS Group AG](https://holderbook.com/funds/1610520-ubs-group-ag/) | $38.1K | 58,597 | 0.0% | 4 |
| [STALEY CAPITAL ADVISERS INC](https://holderbook.com/funds/1106565-staley-capital-advisers-inc/) | $33.5K | 51,472 | 0.0% | 22 |
| [BlackRock, Inc.](https://holderbook.com/funds/2012383-blackrock-inc/) | $28.9K | 44,405 | 0.0% | 8 |
| [NORTHERN TRUST CORP](https://holderbook.com/funds/73124-northern-trust-corp/) | $28.4K | 43,677 | 0.0% | 11 |
| [JANE STREET GROUP, LLC](https://holderbook.com/funds/1595888-jane-street-group-llc/) | $26.7K | 40,974 | 0.0% | 5 |

## Quarter by quarter

| Quarter | Holders | Reported value |
|---|---|---|
| Q2 2026 | 47 | $12.1M |
| Q1 2026 | 44 | $9.2M |
| Q4 2025 | 42 | $5.4M |
| Q3 2025 | 34 | $1.3M |
| Q2 2025 | 46 | $13.4M |
| Q1 2025 | 38 | $11.5M |
| Q4 2024 | 35 | $23.4M |
| Q3 2024 | 33 | $15.0M |
| Q2 2024 | 32 | $16.1M |
| Q1 2024 | 32 | $22.9M |
| Q4 2023 | 33 | $18.4M |
| Q3 2023 | 21 | $1.5M |