# SPYRE THERAPEUTICS INC (SYRE)

> Institutional ownership reported to the SEC as of Q3 2026, from Form 13F filings. Source: https://holderbook.com/stocks/SYRE/

- Reporting holders: 2
- Reported value: $172.3K
- Held through calls: 0.0%
- Held through puts: 0.0%

A 13F reports long US equity positions only. Shorts, bonds, foreign listings and cash are not visible here, and positions are disclosed up to 45 days after the quarter ends.

## Largest holders

| Manager | Value | Shares | Share of their book | Quarters held |
|---|---|---|---|---|
| [Farther Finance Advisors, LLC](https://holderbook.com/funds/1992825-farther-finance-advisors-llc/) | $98.8K | 1,110 | 0.0% | 5 |
| [GAMMA Investing LLC](https://holderbook.com/funds/2010235-gamma-investing-llc/) | $73.5K | 825 | 0.0% | 7 |

## Quarter by quarter

| Quarter | Holders | Reported value |
|---|---|---|
| Q3 2026 | 2 | $172.3K |
| Q2 2026 | 268 | $8.9B |
| Q1 2026 | 197 | $4.2B |
| Q4 2025 | 154 | $2.7B |
| Q3 2025 | 138 | $1.1B |
| Q2 2025 | 129 | $954.3M |
| Q1 2025 | 130 | $1.0B |
| Q4 2024 | 129 | $1.4B |
| Q3 2024 | 118 | $1.5B |
| Q2 2024 | 106 | $1.2B |
| Q1 2024 | 102 | $1.2B |
| Q4 2023 | 55 | $601.0M |