# REPARE THERAPEUTICS INC (RPTX)

> Institutional ownership reported to the SEC as of Q4 2025, from Form 13F filings. Source: https://holderbook.com/stocks/RPTX/

- Reporting holders: 49
- Reported value: $67.2M
- Held through calls: 1.3%
- Held through puts: 0.8%

A 13F reports long US equity positions only. Shorts, bonds, foreign listings and cash are not visible here, and positions are disclosed up to 45 days after the quarter ends.

## Largest holders

| Manager | Value | Shares | Share of their book | Quarters held |
|---|---|---|---|---|
| [BVF INC/IL](https://holderbook.com/funds/1056807-bvf-inc-il/) | $26.9M | 10,333,600 | 0.9% | 23 |
| [Blue Owl Capital Holdings LP](https://holderbook.com/funds/1858703-blue-owl-capital-holdings-lp/) | $9.0M | 3,443,659 | 2.8% | 9 |
| [ORBIMED ADVISORS LLC](https://holderbook.com/funds/1055951-orbimed-advisors-llc/) | $8.6M | 3,322,488 | 0.2% | 23 |
| [Redmile Group, LLC](https://holderbook.com/funds/1425738-redmile-group-llc/) | $4.1M | 1,586,174 | 0.3% | 23 |
| [Rangeley Capital, LLC](https://holderbook.com/funds/1517796-rangeley-capital-llc/) | $3.3M | 1,287,829 | 2.8% | 3 |
| [MARSHALL WACE, LLP](https://holderbook.com/funds/1318757-marshall-wace-llp/) | $2.9M | 1,115,744 | 0.0% | 1 |
| [RENAISSANCE TECHNOLOGIES LLC](https://holderbook.com/funds/1037389-renaissance-technologies-llc/) | $2.6M | 981,360 | 0.0% | 19 |
| [ACADIAN ASSET MANAGEMENT LLC](https://holderbook.com/funds/916542-acadian-asset-management-llc/) | $1.6M | 618,672 | 0.0% | 13 |
| [JANE STREET GROUP, LLC](https://holderbook.com/funds/1595888-jane-street-group-llc/) | $967.2K | 278,304 | 0.0% | 1 |
| [TWO SIGMA INVESTMENTS, LP](https://holderbook.com/funds/1179392-two-sigma-investments-lp/) | $867.6K | 333,694 | 0.0% | 3 |
| [Yakira Capital Management, Inc.](https://holderbook.com/funds/1584639-yakira-capital-management-inc/) | $693.2K | 266,601 | 0.2% | 1 |
| [NORTHERN TRUST CORP](https://holderbook.com/funds/73124-northern-trust-corp/) | $676.8K | 260,311 | 0.0% | 4 |
| [CITADEL ADVISORS LLC](https://holderbook.com/funds/1423053-citadel-advisors-llc/) | $663.8K | 238,912 | 0.0% | 4 |
| [EQUITEC PROPRIETARY MARKETS, LLC](https://holderbook.com/funds/1143261-equitec-proprietary-markets-llc/) | $647.6K | 118,375 | 0.4% | 1 |
| [Militia Capital Partners, LP](https://holderbook.com/funds/1837496-militia-capital-partners-lp/) | $619.7K | 238,352 | 0.1% | 3 |
| [SUSQUEHANNA INTERNATIONAL GROUP, LLP](https://holderbook.com/funds/1446194-susquehanna-international-group-llp/) | $541.8K | 0 | 0.0% | 4 |
| [BlackRock, Inc.](https://holderbook.com/funds/2012383-blackrock-inc/) | $375.0K | 144,219 | 0.0% | 6 |
| [XTX Topco Ltd](https://holderbook.com/funds/1828301-xtx-topco-ltd/) | $304.0K | 116,933 | 0.0% | 3 |
| [Walleye Capital LLC](https://holderbook.com/funds/1758720-walleye-capital-llc/) | $277.4K | 106,683 | 0.0% | 1 |
| [BANK OF MONTREAL /CAN/](https://holderbook.com/funds/927971-bank-of-montreal-can/) | $272.8K | 104,919 | 0.0% | 23 |
| [SIMPLEX TRADING, LLC](https://holderbook.com/funds/1488542-simplex-trading-llc/) | $201.8K | 0 | 0.0% | 3 |
| [TWO SIGMA ADVISERS, LP](https://holderbook.com/funds/1478735-two-sigma-advisers-lp/) | $140.9K | 54,200 | 0.0% | 3 |
| [Point72 Asset Management, L.P.](https://holderbook.com/funds/1603466-point72-asset-management-l-p/) | $133.3K | 51,252 | 0.0% | 1 |
| [HRT FINANCIAL LP](https://holderbook.com/funds/1475597-hrt-financial-lp/) | $109.0K | 42,301 | 0.0% | 1 |
| [Quinn Opportunity Partners LLC](https://holderbook.com/funds/1633275-quinn-opportunity-partners-llc/) | $104.0K | 40,000 | 0.0% | 3 |

## Quarter by quarter

| Quarter | Holders | Reported value |
|---|---|---|
| Q4 2025 | 49 | $67.2M |
| Q3 2025 | 47 | $48.8M |
| Q2 2025 | 50 | $38.9M |
| Q1 2025 | 50 | $29.1M |
| Q4 2024 | 53 | $40.1M |
| Q3 2024 | 56 | $111.4M |
| Q2 2024 | 62 | $111.7M |
| Q1 2024 | 71 | $170.1M |
| Q4 2023 | 69 | $269.6M |
| Q3 2023 | 76 | $451.9M |
| Q2 2023 | 78 | $379.7M |
| Q1 2023 | 77 | $336.3M |