# SPARK THERAPEUTICS INC (ONCE)

> Institutional ownership reported to the SEC as of Q3 2019, from Form 13F filings. Source: https://holderbook.com/stocks/ONCE/

- Reporting holders: 190
- Reported value: $3.8B
- Held through calls: 2.9%
- Held through puts: 5.4%

A 13F reports long US equity positions only. Shorts, bonds, foreign listings and cash are not visible here, and positions are disclosed up to 45 days after the quarter ends.

## Largest holders

| Manager | Value | Shares | Share of their book | Quarters held |
|---|---|---|---|---|
| [VANGUARD GROUP INC](https://holderbook.com/funds/102909-vanguard-group-inc/) | $314.0M | 3,237,616 | 0.0% | 4 |
| [Pentwater Capital Management LP](https://holderbook.com/funds/1425851-pentwater-capital-management-lp/) | $300.8M | 2,103,545 | 4.7% | 2 |
| [BlackRock Inc.](https://holderbook.com/funds/1364742-blackrock-inc/) | $278.3M | 2,869,885 | 0.0% | 4 |
| [BOXER CAPITAL, LLC](https://holderbook.com/funds/1465837-boxer-capital-llc/) | $160.0M | 1,650,000 | 11.6% | 2 |
| [PAULSON & CO. INC.](https://holderbook.com/funds/1035674-paulson-co-inc/) | $139.4M | 1,437,666 | 2.8% | 2 |
| [STATE STREET CORP](https://holderbook.com/funds/93751-state-street-corp/) | $128.4M | 1,324,061 | 0.0% | 4 |
| [CITADEL ADVISORS LLC](https://holderbook.com/funds/1423053-citadel-advisors-llc/) | $102.6M | 654,852 | 0.0% | 4 |
| [Casdin Capital, LLC](https://holderbook.com/funds/1534261-casdin-capital-llc/) | $83.7M | 863,300 | 8.7% | 4 |
| [CNH PARTNERS LLC](https://holderbook.com/funds/1167456-cnh-partners-llc/) | $83.2M | 857,478 | 1.2% | 3 |
| [ALPINE ASSOCIATES MANAGEMENT INC.](https://holderbook.com/funds/1396835-alpine-associates-management-inc/) | $78.4M | 808,900 | 2.6% | 3 |
| [Magnetar Financial LLC](https://holderbook.com/funds/1352851-magnetar-financial-llc/) | $75.8M | 782,108 | 1.9% | 3 |
| [BAKER BROS. ADVISORS LP](https://holderbook.com/funds/1263508-baker-bros-advisors-lp/) | $72.9M | 751,927 | 0.5% | 4 |
| [EcoR1 Capital, LLC](https://holderbook.com/funds/1587114-ecor1-capital-llc/) | $69.3M | 714,789 | 8.8% | 4 |
| [TIG Advisors, LLC](https://holderbook.com/funds/1358253-tig-advisors-llc/) | $64.2M | 633,734 | 2.9% | 2 |
| [JPMORGAN CHASE & CO](https://holderbook.com/funds/19617-jpmorgan-chase-co/) | $57.2M | 499,936 | 0.0% | 4 |
| [ADAGE CAPITAL PARTNERS GP, L.L.C.](https://holderbook.com/funds/1165408-adage-capital-partners-gp-l-l-c/) | $56.7M | 584,332 | 0.1% | 3 |
| [GABELLI FUNDS LLC](https://holderbook.com/funds/1081407-gabelli-funds-llc/) | $52.4M | 540,240 | 0.3% | 3 |
| [Verition Fund Management LLC](https://holderbook.com/funds/1454027-verition-fund-management-llc/) | $52.1M | 0 | 1.4% | 1 |
| [Rock Springs Capital Management LP](https://holderbook.com/funds/1595725-rock-springs-capital-management-lp/) | $49.0M | 505,371 | 2.0% | 4 |
| [GOLDMAN SACHS GROUP INC](https://holderbook.com/funds/886982-goldman-sachs-group-inc/) | $47.9M | 494,248 | 0.0% | 4 |
| [MILLENNIUM MANAGEMENT LLC](https://holderbook.com/funds/1273087-millennium-management-llc/) | $47.9M | 493,633 | 0.1% | 3 |
| [Sofinnova Investments, Inc.](https://holderbook.com/funds/1631134-sofinnova-investments-inc/) | $46.7M | 481,270 | 4.2% | 4 |
| [GEODE CAPITAL MANAGEMENT, LLC](https://holderbook.com/funds/1214717-geode-capital-management-llc/) | $45.6M | 470,631 | 0.0% | 4 |
| [NORTHERN TRUST CORP](https://holderbook.com/funds/73124-northern-trust-corp/) | $43.5M | 448,257 | 0.0% | 4 |
| [IndexIQ Advisors LLC](https://holderbook.com/funds/1415996-indexiq-advisors-llc/) | $40.5M | 417,350 | 1.4% | 3 |

## Quarter by quarter

| Quarter | Holders | Reported value |
|---|---|---|
| Q3 2019 | 190 | $3.8B |
| Q2 2019 | 198 | $3.8B |
| Q1 2019 | 206 | $4.2B |
| Q4 2018 | 157 | $1.6B |