# AYTU BIOPHARMA INC (AYTU)

> Institutional ownership reported to the SEC as of Q2 2026, from Form 13F filings. Source: https://holderbook.com/stocks/AYTU/

- Reporting holders: 38
- Reported value: $20.3M
- Shares held by institutions: 9,962,522 of 10,733,208 outstanding
- Held through calls: 0.0%
- Held through puts: 0.0%

A 13F reports long US equity positions only. Shorts, bonds, foreign listings and cash are not visible here, and positions are disclosed up to 45 days after the quarter ends.

## Largest holders

| Manager | Value | Shares | Share of their book | Quarters held |
|---|---|---|---|---|
| [Stonepine Capital Management, LLC](https://holderbook.com/funds/1440771-stonepine-capital-management-llc/) | $11.6M | 5,903,159 | 3.0% | 13 |
| [Nantahala Capital Management, LLC](https://holderbook.com/funds/1472322-nantahala-capital-management-llc/) | $4.7M | 2,173,624 | 0.1% | 14 |
| [AWM Investment Company, Inc.](https://holderbook.com/funds/1535264-awm-investment-company-inc/) | $1.3M | 619,574 | 0.1% | 5 |
| [VANGUARD CAPITAL MANAGEMENT LLC](https://holderbook.com/funds/2100119-vanguard-capital-management-llc/) | $561.5K | 261,146 | 0.0% | 2 |
| [CROWN ADVISORS MANAGEMENT, INC.](https://holderbook.com/funds/1733248-crown-advisors-management-inc/) | $430.0K | 200,000 | 0.2% | 2 |
| [DIADEMA PARTNERS LP](https://holderbook.com/funds/2026172-diadema-partners-lp/) | $319.4K | 148,546 | 0.0% | 4 |
| [TWO SIGMA INVESTMENTS, LP](https://holderbook.com/funds/1179392-two-sigma-investments-lp/) | $226.5K | 105,326 | 0.0% | 5 |
| [RENAISSANCE TECHNOLOGIES LLC](https://holderbook.com/funds/1037389-renaissance-technologies-llc/) | $225.4K | 104,823 | 0.0% | 14 |
| [CITADEL ADVISORS LLC](https://holderbook.com/funds/1423053-citadel-advisors-llc/) | $212.5K | 98,828 | 0.0% | 3 |
| [GEODE CAPITAL MANAGEMENT, LLC](https://holderbook.com/funds/1214717-geode-capital-management-llc/) | $201.4K | 93,647 | 0.0% | 14 |
| [VANGUARD FIDUCIARY TRUST CO](https://holderbook.com/funds/933478-vanguard-fiduciary-trust-co/) | $101.2K | 47,048 | 0.0% | 2 |
| [DIMENSIONAL FUND ADVISORS LP](https://holderbook.com/funds/354204-dimensional-fund-advisors-lp/) | $97.5K | 45,326 | 0.0% | 4 |
| [Persistent Asset Partners Ltd](https://holderbook.com/funds/2056052-persistent-asset-partners-ltd/) | $81.7K | 37,984 | 0.0% | 4 |
| [NORTHERN TRUST CORP](https://holderbook.com/funds/73124-northern-trust-corp/) | $60.0K | 27,925 | 0.0% | 3 |
| [BELLEVUE ASSET MANAGEMENT, LLC](https://holderbook.com/funds/1801619-bellevue-asset-management-llc/) | $53.8K | 25,013 | 0.0% | 3 |
| [BlackRock, Inc.](https://holderbook.com/funds/2012383-blackrock-inc/) | $49.0K | 22,793 | 0.0% | 8 |
| [XTX Topco Ltd](https://holderbook.com/funds/1828301-xtx-topco-ltd/) | $46.0K | 21,416 | 0.0% | 3 |
| [Daytona Street Capital LLC](https://holderbook.com/funds/2101936-daytona-street-capital-llc/) | $22.4K | 10,000 | 0.0% | 3 |
| [ACADIAN ASSET MANAGEMENT LLC](https://holderbook.com/funds/916542-acadian-asset-management-llc/) | $22.0K | 10,237 | 0.0% | 14 |
| [UBS Group AG](https://holderbook.com/funds/1610520-ubs-group-ag/) | $5.1K | 2,377 | 0.0% | 14 |
| [Tower Research Capital LLC (TRC)](https://holderbook.com/funds/1533421-tower-research-capital-llc-trc/) | $4.8K | 2,232 | 0.0% | 14 |
| [ROYAL BANK OF CANADA](https://holderbook.com/funds/1000275-royal-bank-of-canada/) | $1.0K | 378 | 0.0% | 1 |
| [OSAIC HOLDINGS, INC.](https://holderbook.com/funds/1677044-osaic-holdings-inc/) | $991 | 462 | 0.0% | 14 |
| [JPMORGAN CHASE & CO](https://holderbook.com/funds/19617-jpmorgan-chase-co/) | $337 | 154 | 0.0% | 2 |
| [WELLS FARGO & COMPANY/MN](https://holderbook.com/funds/72971-wells-fargo-company-mn/) | $273 | 127 | 0.0% | 14 |

## Quarter by quarter

| Quarter | Holders | Reported value |
|---|---|---|
| Q2 2026 | 38 | $20.3M |
| Q1 2026 | 33 | $10.7M |
| Q4 2025 | 37 | $9.8M |
| Q3 2025 | 31 | $6.7M |
| Q2 2025 | 31 | $7.4M |
| Q1 2025 | 30 | $2.5M |
| Q4 2024 | 28 | $3.2M |
| Q3 2024 | 23 | $4.8M |
| Q2 2024 | 27 | $9.4M |
| Q1 2024 | 26 | $5.5M |
| Q4 2023 | 22 | $8.4M |
| Q3 2023 | 19 | $4.7M |