# BB BIOTECH AG

> Institutional holdings reported to the SEC as of Q1 2019 on Form 13F. CIK 924223. Source: https://holderbook.com/funds/924223-bb-biotech-ag/

- Reported value: $4.0B
- Positions: 35
- Weight of the ten largest: 64.7%
- Filed: 2019-05-13

A 13F reports long US equity positions only. Short positions, bonds, foreign listings, private holdings and cash are not visible, so this is not the manager's whole book.

## Holdings

| Security | Ticker | Value | Shares | Weight | Quarters held |
|---|---|---|---|---|---|
| IONIS PHARMACEUTICALS INC | [IONS](https://holderbook.com/stocks/IONS/) | $627.0M | 7,725,000 | 15.8% | 2 |
| INCYTE CORP | [INCY](https://holderbook.com/stocks/INCY/) | $311.4M | 3,620,000 | 7.8% | 2 |
| NEUROCRINE BIOSCIENCES INC | [NBIX](https://holderbook.com/stocks/NBIX/) | $296.6M | 3,366,786 | 7.5% | 2 |
| VERTEX PHARMACEUTICALS INC | [VRTX](https://holderbook.com/stocks/VRTX/) | $239.1M | 1,300,000 | 6.0% | 2 |
| SAGE THERAPEUTICS INC | [SAGE](https://holderbook.com/stocks/SAGE/) | $218.7M | 1,375,229 | 5.5% | 2 |
| CELGENE CORP | [CELG](https://holderbook.com/stocks/CELG/) | $207.5M | 2,200,000 | 5.2% | 2 |
| AGIOS PHARMACEUTICALS INC | [AGIO](https://holderbook.com/stocks/AGIO/) | $200.8M | 2,978,134 | 5.0% | 2 |
| ALEXION PHARMACEUTICALS INC | [ALXN](https://holderbook.com/stocks/ALXN/) | $177.7M | 1,314,428 | 4.5% | 2 |
| ALNYLAM PHARMACEUTICALS INC | [ALNY](https://holderbook.com/stocks/ALNY/) | $152.4M | 1,631,089 | 3.8% | 2 |
| ESPERION THERAPEUTICS INC NE | [ESPR](https://holderbook.com/stocks/ESPR/) | $141.4M | 3,522,964 | 3.6% | 2 |
| RADIUS HEALTH INC | [RDUS](https://holderbook.com/stocks/RDUS/) | $135.2M | 6,781,685 | 3.4% | 2 |
| HALOZYME THERAPEUTICS INC | [HALO](https://holderbook.com/stocks/HALO/) | $134.0M | 8,322,860 | 3.4% | 2 |
| ARGENX SE | [ARGX](https://holderbook.com/stocks/ARGX/) | $112.9M | 904,739 | 2.8% | 2 |
| MODERNA INC | [MRNA](https://holderbook.com/stocks/MRNA/) | $97.4M | 4,785,681 | 2.4% | 2 |
| MYOVANT SCIENCES LTD | [MYOV](https://holderbook.com/stocks/MYOV/) | $85.9M | 3,597,882 | 2.2% | 2 |
| INTERCEPT PHARMACEUTICALS IN | [ICPT](https://holderbook.com/stocks/ICPT/) | $78.0M | 696,976 | 2.0% | 2 |
| GILEAD SCIENCES INC | [GILD](https://holderbook.com/stocks/GILD/) | $74.3M | 1,142,204 | 1.9% | 2 |
| NEKTAR THERAPEUTICS | [NKTR](https://holderbook.com/stocks/NKTR/) | $67.9M | 2,020,676 | 1.7% | 2 |
| EXELIXIS INC | [EXEL](https://holderbook.com/stocks/EXEL/) | $67.5M | 2,835,000 | 1.7% | 2 |
| AKCEA THERAPEUTICS INC | [AKCA](https://holderbook.com/stocks/AKCA/) | $67.4M | 2,377,638 | 1.7% | 2 |
| MYOKARDIA INC | [MYOK](https://holderbook.com/stocks/MYOK/) | $65.8M | 1,264,913 | 1.7% | 2 |
| MACROGENICS INC | [MGNX](https://holderbook.com/stocks/MGNX/) | $61.1M | 3,400,000 | 1.5% | 2 |
| WAVE LIFE SCIENCES LTD | [WVE](https://holderbook.com/stocks/WVE/) | $56.9M | 1,465,002 | 1.4% | 2 |
| VOYAGER THERAPEUTICS INC | [VYGR](https://holderbook.com/stocks/VYGR/) | $54.9M | 2,865,841 | 1.4% | 2 |
| AUDENTES THERAPEUTICS INC | [BOLD](https://holderbook.com/stocks/BOLD/) | $53.4M | 1,369,604 | 1.3% | 2 |
| ALDER BIOPHARMACEUTICALS INC | [ALDR](https://holderbook.com/stocks/ALDR/) | $37.8M | 2,766,008 | 0.9% | 2 |
| CRISPR THERAPEUTICS AG | [CRSP](https://holderbook.com/stocks/CRSP/) | $28.9M | 810,462 | 0.7% | 1 |
| SCHOLAR ROCK HLDG CORP | [SRRK](https://holderbook.com/stocks/SRRK/) | $27.8M | 1,476,839 | 0.7% | 2 |
| INTRA-CELLULAR THERAPIES INC | [ITCI](https://holderbook.com/stocks/ITCI/) | $26.8M | 2,200,000 | 0.7% | 2 |
| SANGAMO THERAPEUTICS INC | [SGMOQ](https://holderbook.com/stocks/SGMOQ/) | $25.3M | 2,650,000 | 0.6% | 2 |
| KEZAR LIFE SCIENCES INC | [KZR](https://holderbook.com/stocks/KZR/) | $21.7M | 1,220,503 | 0.5% | 2 |
| G1 THERAPEUTICS INC | [GTHX](https://holderbook.com/stocks/GTHX/) | $11.2M | 671,925 | 0.3% | 2 |
| CIDARA THERAPEUTICS INC COM NEW | [CDTXXXXX](https://holderbook.com/stocks/CDTXXXXX/) | $6.1M | 2,295,272 | 0.2% | 2 |
| NOVAVAX INC | [NVAXXXXX](https://holderbook.com/stocks/NVAXXXXX/) | $4.6M | 8,330,000 | 0.1% | 2 |
| HOMOLOGY MEDICINES INC | [FIXX](https://holderbook.com/stocks/FIXX/) | $2.5M | 91,336 | 0.1% | 1 |

## What the disclosed book did

Not the fund's return. This is the change in value of the positions disclosed on Form 13F, had they been left untouched, against SPY over the same quarter ends.

| Quarter | Book | Market | Difference | Priced |
|---|---|---|---|---|
| Q1 2019 | +27.5% | +13.0% | +14.5% | 100% |

## Quarter by quarter

| Quarter | Value | Positions |
|---|---|---|
| Q1 2019 | $4.0B | 35 |
| Q4 2018 | $3.1B | 34 |