# Tekla Capital Management LLC

> Institutional holdings reported to the SEC as of Q2 2023 on Form 13F. CIK 1300336. Source: https://holderbook.com/funds/1300336-tekla-capital-management-llc/

- Reported value: $2.6B
- Positions: 166
- Weight of the ten largest: 40.3%
- Filed: 2023-08-10

A 13F reports long US equity positions only. Short positions, bonds, foreign listings, private holdings and cash are not visible, so this is not the manager's whole book.

## Holdings

| Security | Ticker | Value | Shares | Weight | Quarters held |
|---|---|---|---|---|---|
| AMGEN INC | [AMGN](https://holderbook.com/stocks/AMGN/) | $136.9M | 616,539 | 5.4% | 19 |
| JOHNSON & JOHNSON | [JNJ](https://holderbook.com/stocks/JNJ/) | $119.5M | 721,779 | 4.7% | 19 |
| GILEAD SCIENCES INC | [GILD](https://holderbook.com/stocks/GILD/) | $118.2M | 1,533,884 | 4.6% | 19 |
| REGENERON PHARMACEUTICALS | [REGN](https://holderbook.com/stocks/REGN/) | $116.0M | 161,418 | 4.5% | 19 |
| VERTEX PHARMACEUTICALS INC | [VRTX](https://holderbook.com/stocks/VRTX/) | $111.9M | 318,043 | 4.4% | 19 |
| ELI LILLY & CO | [LLY](https://holderbook.com/stocks/LLY/) | $100.1M | 213,352 | 3.9% | 19 |
| UNITEDHEALTH GROUP INC | [UNH](https://holderbook.com/stocks/UNH/) | $99.5M | 206,961 | 3.9% | 19 |
| MERCK & CO INC | [MRK](https://holderbook.com/stocks/MRK/) | $84.0M | 728,154 | 3.3% | 19 |
| ABBVIE INC | [ABBV](https://holderbook.com/stocks/ABBV/) | $73.5M | 545,629 | 2.9% | 19 |
| BIOGEN INC | [BIIB](https://holderbook.com/stocks/BIIB/) | $70.6M | 247,943 | 2.8% | 19 |
| ASTRAZENECA PLC | [AZN](https://holderbook.com/stocks/AZN/) | $69.9M | 976,676 | 2.7% | 19 |
| ILLUMINA INC | [ILMN](https://holderbook.com/stocks/ILMN/) | $63.2M | 336,979 | 2.5% | 19 |
| ABBOTT LABORATORIES | [ABT](https://holderbook.com/stocks/ABT/) | $60.2M | 552,455 | 2.4% | 19 |
| PFIZER INC | [PFE](https://holderbook.com/stocks/PFE/) | $59.6M | 1,624,476 | 2.3% | 19 |
| THERMO FISHER SCIENTIFIC INC | [TMO](https://holderbook.com/stocks/TMO/) | $51.6M | 98,987 | 2.0% | 19 |
| ELEVANCE HEALTH INC FORMERLY | [ELV](https://holderbook.com/stocks/ELV/) | $50.7M | 114,070 | 2.0% | 19 |
| MODERNA INC | [MRNA](https://holderbook.com/stocks/MRNA/) | $41.8M | 343,695 | 1.6% | 14 |
| BOSTON SCIENTIFIC CORP | [BSX](https://holderbook.com/stocks/BSX/) | $35.6M | 657,790 | 1.4% | 19 |
| DANAHER CORP DEL | [DHR](https://holderbook.com/stocks/DHR/) | $34.3M | 142,813 | 1.3% | 19 |
| MEDTRONIC PLC | [MDT](https://holderbook.com/stocks/MDT/) | $30.3M | 344,417 | 1.2% | 19 |
| IDEXX LABS INC | [IDXX](https://holderbook.com/stocks/IDXX/) | $29.4M | 58,595 | 1.2% | 19 |
| DEXCOM INC | [DXCM](https://holderbook.com/stocks/DXCM/) | $29.4M | 228,747 | 1.2% | 13 |
| BRISTOL-MYERS SQUIBB CO | [BMY](https://holderbook.com/stocks/BMY/) | $29.3M | 458,498 | 1.1% | 19 |
| INTUITIVE SURGICAL INC | [ISRG](https://holderbook.com/stocks/ISRG/) | $28.7M | 83,980 | 1.1% | 19 |
| ALNYLAM PHARMACEUTICALS INC | [ALNY](https://holderbook.com/stocks/ALNY/) | $27.2M | 143,214 | 1.1% | 19 |
| THE CIGNA GROUP | [CI](https://holderbook.com/stocks/CI/) | $27.0M | 96,339 | 1.1% | 19 |
| MCKESSON CORP | [MCK](https://holderbook.com/stocks/MCK/) | $26.5M | 61,955 | 1.0% | 19 |
| ARGENX SE | [ARGX](https://holderbook.com/stocks/ARGX/) | $25.5M | 65,553 | 1.0% | 18 |
| HCA HEALTHCARE INC | [HCA](https://holderbook.com/stocks/HCA/) | $25.0M | 82,403 | 1.0% | 19 |
| STRYKER CORPORATION | [SYK](https://holderbook.com/stocks/SYK/) | $24.8M | 81,128 | 1.0% | 19 |
| IQVIA HLDGS INC | [IQV](https://holderbook.com/stocks/IQV/) | $24.5M | 109,129 | 1.0% | 19 |
| ZOETIS INC | [ZTS](https://holderbook.com/stocks/ZTS/) | $23.6M | 136,914 | 0.9% | 19 |
| CHARLES RIV LABS INTL INC | [CRL](https://holderbook.com/stocks/CRL/) | $23.4M | 111,183 | 0.9% | 19 |
| SEAGEN INC | [SGEN](https://holderbook.com/stocks/SGEN/) | $21.6M | 112,331 | 0.8% | 11 |
| SAREPTA THERAPEUTICS INC | [SRPT](https://holderbook.com/stocks/SRPT/) | $20.5M | 179,437 | 0.8% | 19 |
| NOVO-NORDISK A S | [NVO](https://holderbook.com/stocks/NVO/) | $19.9M | 122,777 | 0.8% | 19 |
| Oculis Holding AG | - | $18.8M | 1,690,741 | 0.7% | 2 |
| MOLINA HEALTHCARE INC | [MOH](https://holderbook.com/stocks/MOH/) | $18.6M | 61,856 | 0.7% | 13 |
| JAZZ PHARMACEUTICALS PLC | [JAZZ](https://holderbook.com/stocks/JAZZ/) | $18.3M | 147,779 | 0.7% | 19 |
| BIOMARIN PHARMACEUTICAL INC | [BMRN](https://holderbook.com/stocks/BMRN/) | $18.3M | 210,789 | 0.7% | 19 |
| EDWARDS LIFESCIENCES CORP | [EW](https://holderbook.com/stocks/EW/) | $17.9M | 189,597 | 0.7% | 19 |
| HUMANA INC | [HUM](https://holderbook.com/stocks/HUM/) | $16.5M | 36,794 | 0.6% | 19 |
| APELLIS PHARMACEUTICALS INC | [APLS](https://holderbook.com/stocks/APLS/) | $15.8M | 173,248 | 0.6% | 16 |
| BAXTER INTL INC | [BAX](https://holderbook.com/stocks/BAX/) | $14.8M | 324,370 | 0.6% | 2 |
| EXELIXIS INC | [EXEL](https://holderbook.com/stocks/EXEL/) | $13.9M | 726,639 | 0.5% | 2 |
| NOVARTIS AG | [NVS](https://holderbook.com/stocks/NVS/) | $13.7M | 136,225 | 0.5% | 19 |
| KARUNA THERAPEUTICS INC | [KRTX](https://holderbook.com/stocks/KRTX/) | $12.7M | 58,577 | 0.5% | 13 |
| INSULET CORP | [PODD](https://holderbook.com/stocks/PODD/) | $12.6M | 43,847 | 0.5% | 1 |
| GUARDANT HEALTH INC | [GH](https://holderbook.com/stocks/GH/) | $12.4M | 346,084 | 0.5% | 15 |
| ASCENDIS PHARMA A/S | [ASND](https://holderbook.com/stocks/ASND/) | $12.4M | 138,791 | 0.5% | 19 |
| SPDR SERIES TRUST | [XBI](https://holderbook.com/stocks/XBI/) | $12.3M | 147,677 | 0.5% | 6 |
| PHYSICIANS RLTY TR | [DOCXXXX](https://holderbook.com/stocks/DOCXXXX/) | $12.2M | 873,655 | 0.5% | 19 |
| TENET HEALTHCARE CORP | [THC](https://holderbook.com/stocks/THC/) | $12.1M | 149,070 | 0.5% | 1 |
| BIONTECH SE | [BNTX](https://holderbook.com/stocks/BNTX/) | $11.2M | 103,858 | 0.4% | 10 |
| NEUROCRINE BIOSCIENCES INC | [NBIX](https://holderbook.com/stocks/NBIX/) | $10.6M | 112,908 | 0.4% | 19 |
| ZIMMER BIOMET HOLDINGS INC | [ZBH](https://holderbook.com/stocks/ZBH/) | $9.8M | 67,356 | 0.4% | 19 |
| RALLYBIO CORP | [RLYB](https://holderbook.com/stocks/RLYB/) | $9.8M | 1,727,067 | 0.4% | 8 |
| VAXCYTE INC | [PCVX](https://holderbook.com/stocks/PCVX/) | $9.7M | 194,232 | 0.4% | 3 |
| ALKERMES PLC | [ALKS](https://holderbook.com/stocks/ALKS/) | $9.7M | 309,613 | 0.4% | 8 |
| DENALI THERAPEUTICS INC | [DNLI](https://holderbook.com/stocks/DNLI/) | $9.6M | 324,829 | 0.4% | 11 |
| AVANTOR INC | [AVTR](https://holderbook.com/stocks/AVTR/) | $9.4M | 459,488 | 0.4% | 3 |
| OMEGA HEALTHCARE INVS INC | [OHI](https://holderbook.com/stocks/OHI/) | $9.4M | 306,433 | 0.4% | 19 |
| UNITED THERAPEUTICS CORP DEL | [UTHR](https://holderbook.com/stocks/UTHR/) | $9.2M | 41,465 | 0.4% | 19 |
| INTRA-CELLULAR THERAPIES INC | [ITCI](https://holderbook.com/stocks/ITCI/) | $8.3M | 131,435 | 0.3% | 19 |
| ACADIA HEALTHCARE COMPANY IN | [ACHC](https://holderbook.com/stocks/ACHC/) | $8.0M | 100,912 | 0.3% | 6 |
| MADRIGAL PHARMACEUTICALS INC | [MDGL](https://holderbook.com/stocks/MDGL/) | $8.0M | 34,434 | 0.3% | 2 |
| RESMED INC | [RMD](https://holderbook.com/stocks/RMD/) | $7.6M | 34,704 | 0.3% | 19 |
| HORIZON THERAPEUTICS PUB L | [HZNP](https://holderbook.com/stocks/HZNP/) | $7.4M | 72,425 | 0.3% | 1 |
| INSPIRE MED SYS INC | [INSP](https://holderbook.com/stocks/INSP/) | $7.1M | 22,018 | 0.3% | 1 |
| CYTOKINETICS INC | [CYTK](https://holderbook.com/stocks/CYTK/) | $7.1M | 219,025 | 0.3% | 7 |
| STERIS PLC | [STE](https://holderbook.com/stocks/STE/) | $7.0M | 31,072 | 0.3% | 18 |
| SANOFI SA | [SNY](https://holderbook.com/stocks/SNY/) | $6.7M | 123,454 | 0.3% | 19 |
| R1 RCM INC | [RCM](https://holderbook.com/stocks/RCM/) | $6.6M | 356,851 | 0.3% | 5 |
| CVS HEALTH CORP | [CVS](https://holderbook.com/stocks/CVS/) | $6.5M | 93,621 | 0.3% | 19 |
| MEDPACE HLDGS INC | [MEDP](https://holderbook.com/stocks/MEDP/) | $6.5M | 26,918 | 0.3% | 15 |
| IMMUNOVANT INC | [IMVT](https://holderbook.com/stocks/IMVT/) | $6.4M | 336,200 | 0.2% | 2 |
| INTELLIA THERAPEUTICS INC | [NTLA](https://holderbook.com/stocks/NTLA/) | $6.3M | 154,269 | 0.2% | 10 |
| LTC PPTYS INC | [LTC](https://holderbook.com/stocks/LTC/) | $6.0M | 182,293 | 0.2% | 19 |
| SABRA HEALTH CARE REIT INC | [SBRA](https://holderbook.com/stocks/SBRA/) | $6.0M | 510,660 | 0.2% | 19 |
| SMITH & NEPHEW PLC | [SNN](https://holderbook.com/stocks/SNN/) | $5.9M | 181,710 | 0.2% | 19 |
| CHINOOK THERAPEUTICS INC | [KDNY](https://holderbook.com/stocks/KDNY/) | $5.8M | 150,863 | 0.2% | 2 |
| WEST PHARMACEUTICAL SVSC INC | [WST](https://holderbook.com/stocks/WST/) | $5.8M | 15,036 | 0.2% | 2 |
| CEREVEL THERAPEUTICS HLDNG I | [CERE](https://holderbook.com/stocks/CERE/) | $5.6M | 176,483 | 0.2% | 7 |
| LIVANOVA PLC | [LIVN](https://holderbook.com/stocks/LIVN/) | $5.6M | 108,480 | 0.2% | 2 |
| ALLSCRIPTS HEALTHCARE SOLUTN | [MDRX](https://holderbook.com/stocks/MDRX/) | $5.4M | 428,580 | 0.2% | 4 |
| AGILENT TECHNOLOGIES INC | [A](https://holderbook.com/stocks/A/) | $5.2M | 43,191 | 0.2% | 17 |
| MARINUS PHARMACEUTICALS INC | [MRNS](https://holderbook.com/stocks/MRNS/) | $4.5M | 411,101 | 0.2% | 2 |
| UNIQURE NV | [QURE](https://holderbook.com/stocks/QURE/) | $4.1M | 356,280 | 0.2% | 19 |
| CENCORA INC | [COR](https://holderbook.com/stocks/COR/) | $3.9M | 20,417 | 0.2% | 3 |
| MEDICAL PROPERTIES TRUST INC | [MPT](https://holderbook.com/stocks/MPT/) | $3.8M | 411,743 | 0.1% | 19 |
| BEONE MEDICINES LTD | [ONC](https://holderbook.com/stocks/ONC/) | $3.7M | 20,952 | 0.1% | 19 |
| IONIS PHARMACEUTICALS INC | [IONS](https://holderbook.com/stocks/IONS/) | $3.6M | 87,840 | 0.1% | 19 |
| BIOCRYST PHARMACEUTICALS INC | [BCRX](https://holderbook.com/stocks/BCRX/) | $3.6M | 504,528 | 0.1% | 6 |
| REATA PHARMACEUTICALS INC | [RETA](https://holderbook.com/stocks/RETA/) | $3.5M | 34,250 | 0.1% | 2 |
| TEVA PHARMACEUTICAL INDS LTD | [TEVA](https://holderbook.com/stocks/TEVA/) | $3.5M | 459,651 | 0.1% | 19 |
| WELLTOWER INC | [WELL](https://holderbook.com/stocks/WELL/) | $3.4M | 41,484 | 0.1% | 19 |
| HEALTHCARE RLTY TR | [HR](https://holderbook.com/stocks/HR/) | $3.3M | 174,686 | 0.1% | 4 |
| VENTAS INC | [VTR](https://holderbook.com/stocks/VTR/) | $3.2M | 66,681 | 0.1% | 19 |
| ISHARES TR | [IBB](https://holderbook.com/stocks/IBB/) | $3.1M | 24,569 | 0.1% | 4 |
| HEALTHPEAK PROPERTIES INC | [DOC](https://holderbook.com/stocks/DOC/) | $3.0M | 150,392 | 0.1% | 15 |

## What the disclosed book did

Not the fund's return. This is the change in value of the positions disclosed on Form 13F, had they been left untouched, against SPY over the same quarter ends.

| Quarter | Book | Market | Difference | Priced |
|---|---|---|---|---|
| Q2 2023 | +1.0% | +8.3% | -7.3% | 100% |
| Q1 2023 | -2.0% | +7.0% | -9.1% | 100% |
| Q4 2022 | +11.4% | +7.1% | +4.4% | 100% |
| Q3 2022 | -2.0% | -5.3% | +3.3% | 100% |
| Q2 2022 | -8.2% | -16.5% | +8.3% | 100% |
| Q1 2022 | -6.3% | -4.9% | -1.4% | 99% |
| Q4 2021 | +0.9% | +10.7% | -9.8% | 100% |
| Q3 2021 | -0.3% | +0.3% | -0.6% | 100% |

## Quarter by quarter

| Quarter | Value | Positions |
|---|---|---|
| Q2 2023 | $2.6B | 166 |
| Q1 2023 | $2.6B | 177 |
| Q4 2022 | $2.6B | 172 |
| Q3 2022 | $2.4B | 168 |
| Q2 2022 | $2.5B | 177 |
| Q1 2022 | $2.8B | 175 |
| Q4 2021 | $3.1B | 171 |
| Q3 2021 | $3.1B | 172 |
| Q2 2021 | $3.1B | 189 |
| Q1 2021 | $2.9B | 196 |
| Q4 2020 | $2.8B | 200 |
| Q3 2020 | $2.7B | 204 |